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Works (10)

Target Class Profiling of Small-Molecule Methyltransferases

ACS Chemical Biology
2023-04-21 | Journal article
DOI: 10.1021/acschembio.3c00124
Contributors: Quinlin M. Hanson; Nate Hoxie; Min Shen; Hui Guo; Ig-Jun Cho; Ipsita Chakraborty; Brooklyn M. Aragon; Ganesha Rai; Samarjit Patnaik; John S. Janiszewski et al.
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Selective Inhibitors of Autophagy Reveal New Link between the Cell Cycle and Autophagy and Lead to Discovery of Novel Synergistic Drug Combinations

ACS Chemical Biology
2022-12-16 | Journal article
DOI: 10.1021/acschembio.2c00710
Contributors: Kisa Sung; Agata Kurowski; Carisse Lansiquot; Kanny K. Wan; Samarjit Patnaik; Martin J. Walsh; Michael B. Lazarus
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Discovery and Optimization of Pyrrolopyrimidine Derivatives as Selective Disruptors of the Perinucleolar Compartment, a Marker of Tumor Progression toward Metastasis

Journal of Medicinal Chemistry
2022-06-23 | Journal article
DOI: 10.1021/acs.jmedchem.2c00204
Contributors: Kevin J. Frankowski; Samarjit Patnaik; Chen Wang; Noel Southall; Dipannita Dutta; Soumitta De; Dandan Li; Christopher Dextras; Yi-Han Lin; Marthe Bryant-Connah et al.
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Virtual Screening for the Discovery of Microbiome β-Glucuronidase Inhibitors to Alleviate Cancer Drug Toxicity

Journal of Chemical Information and Modeling
2022-04-11 | Journal article
DOI: 10.1021/acs.jcim.1c01414
Contributors: Anup P. Challa; Xin Hu; Ya-Qin Zhang; Jeffrey Hymes; Bret D. Wallace; Surendra Karavadhi; Hongmao Sun; Samarjit Patnaik; Matthew D. Hall; Min Shen
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Discovery of Small-Molecule VapC1 Nuclease Inhibitors by Virtual Screening and Scaffold Hopping from an Atomic Structure Revealing Protein–Protein Interactions with a Native VapB1 Inhibitor

Journal of Chemical Information and Modeling
2022-03-14 | Journal article
DOI: 10.1021/acs.jcim.1c01188
Contributors: Hongmao Sun; Nathan P. Coussens; Carina Danchik; Leah M. Wachsmuth; Mark J. Henderson; Samarjit Patnaik; Matthew D. Hall; Ashley L. Molinaro; Dayle A. Daines; Min Shen
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The HIV protease inhibitor, ritonavir, corrects diverse brain phenotypes across development in mouse model of DYT-TOR1A dystonia

Science Translational Medicine
2021-08-18 | Journal article
DOI: 10.1126/scitranslmed.abd3904
Contributors: Zachary F. Caffall; Bradley J. Wilkes; Ricardo Hernández-Martinez; Joseph E. Rittiner; Jennifer T. Fox; Kanny K. Wan; Miranda K. Shipman; Steven A. Titus; Ya-Qin Zhang; Samarjit Patnaik et al.
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Correction to Remdesivir: A Review of Its Discovery and Development Leading to Human Clinical Trials for Treatment of COVID-19

ACS Central Science
2020-06-24 | Journal article
DOI: 10.1021/acscentsci.0c00747
Contributors: Richard T. Eastman; Jacob S. Roth; Kyle R. Brimacombe; Anton Simeonov; Min Shen; Samarjit Patnaik; Matthew D. Hall
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Identification, design and synthesis of novel pyrazolopyridine influenza virus nonstructural protein 1 antagonists

Bioorganic & Medicinal Chemistry Letters
2019-05 | Journal article
DOI: 10.1016/j.bmcl.2019.02.027
Contributors: Samarjit Patnaik; Dipanwita Basu; Noel Southall; Seameen Dehdashti; Kanny K. Wan; Wei Zheng; Marc Ferrer; Mercedes Taylor; Daniel A. Engel; Juan Jose Marugan
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Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis

Science Translational Medicine
2018-05-16 | Journal article
DOI: 10.1126/scitranslmed.aap8307
Contributors: Kevin J. Frankowski; Chen Wang; Samarjit Patnaik; Frank J. Schoenen; Noel Southall; Dandan Li; Yaroslav Teper; Wei Sun; Irawati Kandela; Deqing Hu et al.
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Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein

eLife
2017-12-26 | Journal article
DOI: 10.7554/eLife.29123
Contributors: Ismael Al-Ramahi; Sai Srinivas Panapakkam Giridharan; Yu-Chi Chen; Samarjit Patnaik; Nathaniel Safren; Junya Hasegawa; Maria de Haro; Amanda K Wagner Gee; Steven A Titus; Hyunkyung Jeong et al.
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Peer review (8 reviews for 2 publications/grants)

Review activity for Journal of medicinal chemistry. (7)
Review activity for Nature communications (1)
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