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Scopus Author ID: 8703141300

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United Kingdom, Greece

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Employment (2)

Imperial College London: London, GB

(School of Public Health)
Employment
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Imperial College London

Biomedical Research Foundation of the Academy of Athens: Athens, GR

2023-05-01 to present | Research Director
Employment
Source: Self-asserted source
Ioanna Tzoulaki

Works (50 of 183)

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Cross-platform metabolomics imputation using importance-weighted autoencoders

2025-03-06 | Preprint
DOI: 10.1101/2025.03.06.25323475
Contributors: Alexander Smith; Rui Pinto; Loukas Zagkos; Ioanna Tzoulaki; Paul Elliott; Abbas Dehghan
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Identifying clusters of people with Multiple Long-Term Conditions using Large Language Models: a population-based study

2025-02-16 | Preprint
DOI: 10.1101/2025.02.14.25322277
Contributors: Alexander Smith; Thomas Beaney; Carinna Hockham; Bowen Su; Paul Elliott; Laura Downey; Spiros Denaxas; Payam Barnaghi; Abbas Dehghan; Ioanna Tzoulaki
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Sex-specific metabolic signatures of adiposity associated with clinical biomarkers in the UK Biobank

2025-01-28 | Preprint
DOI: 10.1101/2025.01.23.25321010
Contributors: Christos K. Papagiannopoulos; Georgios Markozannes; Christos V. Chalitsios; Sofia Christakoudi; Marc J Gunter; Laure Dossus; Richard M. Martin; Ioanna Tzoulaki; Christopher Papandreou; Konstantinos K. Tsilidis
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Crossref

Metabolic Signatures of Blood Pressure and Risk of Cardiovascular Diseases

Journal of the American Heart Association
2024-11-22 | Journal article
DOI: 10.1161/JAHA.124.036573
Contributors: Maria Manou; Christos Papagiannopoulos; Christos V. Chalitsios; Alexandros‐Georgios Asimakopoulos; Georgios Markozannes; Monica Bulló; Konstantinos K. Tsilidis; Christopher Papandreou; Ioanna Tzoulaki
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PDE5 inhibition and Alzheimer’s disease risk: a mendelian randomisation study

2024-11-18 | Preprint
DOI: 10.1101/2024.11.16.24317338
Contributors: Marta Alcalde-Herraiz; Benjamin Woolf; Junqing Xie; Emma Anderson; Dipender Gill; Ioanna Tzoulaki; Laura M Winchester; James Yarmolinsky; Daniel Prieto-Alhambra; Danielle Newby
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Multi-trait association analysis reveals shared genetic loci between Alzheimer’s disease and cardiovascular traits

Nature Communications
2024-11-13 | Journal article
DOI: 10.1038/s41467-024-53452-6
Contributors: Fotios Koskeridis; Nurun Fancy; Pei Fang Tan; Devendra Meena; Evangelos Evangelou; Paul Elliott; Dennis Wang; Paul M. Matthews; Abbas Dehghan; Ioanna Tzoulaki
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Genome-wide scan of Flortaucipir PET levels findsJARID2associated with cerebral tau deposition

2024-10-06 | Preprint
DOI: 10.1101/2024.10.04.24314853
Contributors: Tamil Iniyan Gunasekaran; Devendra Meena; Annie J Lee; Siwei Wu; Logan Dumitrescu; Reisa Sperling; Timothy J Hohman; Jingxian Huang; Abbas Dehghan; Ioanna Tzoulaki et al.
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Sex inequalities in cardiovascular risk prediction

Cardiovascular Research
2024-09-21 | Journal article
DOI: 10.1093/cvr/cvae123
Contributors: Joshua Elliott; Barbara Bodinier; Matthew Whitaker; Rin Wada; Graham Cooke; Helen Ward; Ioanna Tzoulaki; Paul Elliott; Marc Chadeau-Hyam
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Crossref

Mendelian Randomization and Bayesian Colocalization Analysis Implicate Glycoprotein VI as a Potential Drug Target for Cardioembolic Stroke in South Asian Populations

Journal of the American Heart Association
2024-08-20 | Journal article
DOI: 10.1161/JAHA.124.035008
Contributors: Siwei Wu; Devendra Meena; James Yarmolinsky; Dipender Gill; Alexander Smith; Marie‐Joe Dib; Ganesh Chauhan; Anand Rohatgi; Abbas Dehghan; Ioanna Tzoulaki
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Crossref

Body Mass Index and Hypertension as Mediators of the Association Between Age at Menarche and Subclinical Atherosclerosis: A Sex‐Specific Mendelian Randomization Analysis

Journal of the American Heart Association
2024-07-16 | Journal article
DOI: 10.1161/JAHA.123.032192
Contributors: Devendra Meena; Jian Huang; Marie‐Joe Dib; Julio Chirinos; Manyi Jia; Ganesh Chauhan; Dipender Gill; Paul Elliott; Abbas Dehghan; Ioanna Tzoulaki
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Crossref

RE: Exploring the cross-cancer effect of circulating proteins and discovering potential intervention targets for 13 site-specific cancers

JNCI: Journal of the National Cancer Institute
2024-05-08 | Journal article
DOI: 10.1093/jnci/djae064
Contributors: James Yarmolinsky; Ioanna Tzoulaki; Marc J Gunter; Ruth C Travis; George Davey Smith; Karl Smith-Byrne
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Crossref

Unravelling genetic architecture of circulatory amino acid levels, and their effect on risk of complex disorders

NAR Genomics and Bioinformatics
2024-04-04 | Journal article
DOI: 10.1093/nargab/lqae046
Contributors: Leila Abar; Verena Zuber; Georg W Otto; Ioanna Tzoulaki; Abbas Dehghan
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Crossref

Multiple long-term conditions in people with psoriasis: a latent class and bidirectional Mendelian randomization analysis

British Journal of Dermatology
2024-02-16 | Journal article
DOI: 10.1093/bjd/ljad410
Contributors: Christos V Chalitsios; Devendra Meena; Maria Manou; Christos Papagiannopoulos; Georgios Markozannes; Dipender Gill; Bowen Su; Konstantinos K Tsilidis; Evangelos Evangelou; Ioanna Tzoulaki
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Pleiotropic effects of PLEC and C1Q on Alzheimer’s disease and cardiovascular traits

2024-01-31 | Preprint
DOI: 10.21203/rs.3.rs-3851905/v1
Contributors: Fotios Koskeridis; Nurun Fancy; Pei Fang Tan; Evangelos Evangelou; Devendra Meena; Paul Elliott; Dennis Wang; Paul Matthews; Abbas Dehghan; Ioanna Tzoulaki
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Crossref

Blood DNA methylation signature of diet quality and association with cardiometabolic traits

European Journal of Preventive Cardiology
2024-01-25 | Journal article
DOI: 10.1093/eurjpc/zwad317
Contributors: Jorge Domínguez-Barragán; Alba Fernández-Sanlés; Álvaro Hernáez; Joana Llauradó-Pont; Jaume Marrugat; Oliver Robinson; Ioanna Tzoulaki; Roberto Elosua; Camille Lassale
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Crossref

Cerebrospinal Fluid C1-Esterase Inhibitor and Tie-1 Levels Affect Cognitive Performance: Evidence from Proteome-Wide Mendelian Randomization

Genes
2024-01-04 | Journal article
DOI: 10.3390/genes15010071
Contributors: Loukas Zagkos; Marie-Joe Dib; Héléne T. Cronjé; Paul Elliott; Abbas Dehghan; Ioanna Tzoulaki; Dipender Gill; Iyas Daghlas
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Cardiovascular Efficacy of Lipid-Lowering Drug Targets Is Not Entirely Explained by Apolipoprotein B Reduction: Mendelian Randomization Evidence

Circulation: Genomic and Precision Medicine
2023-10 | Journal article
DOI: 10.1161/CIRCGEN.123.004204
Contributors: Dipender Gill; Benjamin Woolf; Loukas Zagkos; Héléne T. Cronjé; Ioanna Tzoulaki
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Crossref

Psoriasis and COVID-19: A bidirectional Mendelian randomization study

Journal of the American Academy of Dermatology
2023-04 | Journal article
DOI: 10.1016/j.jaad.2022.10.019
Contributors: Christos V. Chalitsios; Kostas K. Tsilidis; Ioanna Tzoulaki
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Crossref

Evidence for Involvement of the Alcohol Consumption WDPCP Gene in Lipid Metabolism, and Liver Cirrhosis

2023-04-17 | Preprint
DOI: 10.21203/rs.3.rs-2823633/v1
Contributors: Raha Pazoki; Felix O’Farrel; Benjamin Aleyakpo; Rima Mustafa; Xiyun Jiang; Rui Pinto; Paul Elliott; Ioanna Tzoulaki; Dehghan Abbas; Samantha Loh et al.
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Crossref

Investigating modifiable pathways in psoriasis: A Mendelian randomization study

Journal of the American Academy of Dermatology
2023-03 | Journal article
DOI: 10.1016/j.jaad.2022.11.010
Contributors: Christos V. Chalitsios; Andrea Georgiou; Emmanouil Bouras; Evangelos Evangelou; Dipender Gill; Kostas K. Tsilidis; Ioanna Tzoulaki
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Crossref

Response to comment on “Psoriasis and COVID-19: A bidirectional Mendelian randomization study”

Journal of the American Academy of Dermatology
2023-03 | Journal article
DOI: 10.1016/j.jaad.2022.11.037
Contributors: Christos V. Chalitsios; Kostas K. Tsilidis; Ioanna Tzoulaki
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Crossref

Improving cardiovascular risk prediction beyond pooled cohort equations: a prospective cohort of 304,356 participants

2023-01-11 | Preprint
DOI: 10.1101/2023.01.09.23284368
Contributors: Joshua Elliott; Barbara Bodinier; Matthew Whitaker; Ioanna Tzoulaki; Paul Elliott; Marc Chadeau-Hyam
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Crossref

Associations of Genetically Predicted Vitamin B12 Status across the Phenome

Nutrients
2022-11-26 | Journal article
DOI: 10.3390/nu14235031
Contributors: Marie-Joe Dib; Kourosh R. Ahmadi; Loukas Zagkos; Dipender Gill; Brooke Morris; Paul Elliott; Abbas Dehghan; Ioanna Tzoulaki
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Pleiotropic genetic architecture and novel loci for C-reactive protein levels

Nature Communications
2022-11-14 | Journal article
DOI: 10.1038/s41467-022-34688-6
Contributors: Fotios Koskeridis; Evangelos Evangelou; Saredo Said; Joseph J. Boyle; Paul Elliott; Abbas Dehghan; Ioanna Tzoulaki
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Crossref

Genetic Evidence for Protective Effects of Angiotensin-Converting Enzyme Against Alzheimer Disease But Not Other Neurodegenerative Diseases in European Populations

Neurology Genetics
2022-10 | Journal article
DOI: 10.1212/NXG.0000000000200014
Contributors: David K. Ryan; Ville Karhunen; Bowen Su; Matthew Traylor; Tom G. Richardson; Stephen Burgess; Ioanna Tzoulaki; Dipender Gill
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Prognostic factors for adverse outcomes in patients with COVID-19: a field-wide systematic review and meta-analysis

European Respiratory Journal
2022-02 | Journal article
DOI: 10.1183/13993003.02964-2020
Contributors: Vanesa Bellou; Ioanna Tzoulaki; Maarten van Smeden; Karel G.M. Moons; Evangelos Evangelou; Lazaros Belbasis
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Crossref

Endogenous sex steroid hormones and colorectal cancer risk: a systematic review and meta-analysis

Discover Oncology
2021-12 | Journal article
DOI: 10.1007/s12672-021-00402-z
Contributors: Emmanouil Bouras; Christopher Papandreou; Ioanna Tzoulaki; Konstantinos K. Tsilidis
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Crossref

Global assessment of C-reactive protein and health-related outcomes: an umbrella review of evidence from observational studies and Mendelian randomization studies

European Journal of Epidemiology
2021-01-25 | Journal article
DOI: 10.1007/s10654-020-00681-w
Contributors: Georgios Markozannes; Charalampia Koutsioumpa; Sofia Cividini; Grace Monori; Konstantinos K. Tsilidis; Nikolaos Kretsavos; Evropi Theodoratou; Dipender Gill; John PA Ioannidis; Ioanna Tzoulaki
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Crossref

Sleep, major depressive disorder, and Alzheimer disease

Neurology
2020-10-06 | Journal article
DOI: 10.1212/WNL.0000000000010463
Contributors: Jian Huang; Verena Zuber; Paul M. Matthews; Paul Elliott; Joanna Tzoulaki; Abbas Dehghan
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Crossref

Risk factors for positive and negative COVID-19 tests: a cautious and in-depth analysis of UK biobank data

International Journal of Epidemiology
2020-10-01 | Journal article
DOI: 10.1093/ije/dyaa134
Contributors: Marc Chadeau-Hyam; Barbara Bodinier; Joshua Elliott; Matthew D Whitaker; Ioanna Tzoulaki; Roel Vermeulen; Michelle Kelly-Irving; Cyrille Delpierre; Paul Elliott
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Crossref

Genetically determined blood pressure, antihypertensive drug classes, and risk of stroke subtypes

Neurology
2020-07-28 | Journal article
DOI: 10.1212/WNL.0000000000009814
Contributors: Marios K. Georgakis; Dipender Gill; Alastair J.S. Webb; Evangelos Evangelou; Paul Elliott; Cathie L.M. Sudlow; Abbas Dehghan; Rainer Malik; Ioanna Tzoulaki; Martin Dichgans
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Crossref

The consequences of adjustment, correction and selection in genome-wide association studies used for two-sample Mendelian randomization

2020-07-14 | Other
DOI: 10.1101/2020.07.13.20152413
Contributors: Venexia M Walker; Sean Harrison; Alice R Carter; Dipender Gill; Ioanna Tzoulaki; Neil M Davies
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Crossref

Dopaminergic stimulants and risk of Parkinson’s disease

2020-05-11 | Other
DOI: 10.1101/2020.05.06.20089748
Contributors: Michael Wainberg; Dipender Gill; Bowen Su; Mike A. Nalls; Robert R. Graham; Sudeshna Das; Ioanna Tzoulaki; Nasa Sinnott-Armstrong; Manuel A. Rivas
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Crossref

Comparison of prognostic models to predict the occurrence of colorectal cancer in asymptomatic individuals: A systematic literature review and external validation in the EPIC and UK Biobank prospective cohort studies

Gut
2019 | Journal article
DOI: 10.1136/gutjnl-2017-315730
EID:

2-s2.0-85054448458
Contributors: Smith, T.; Muller, D.C.; Moons, K.G.M.; Cross, A.J.; Johansson, M.; Ferrari, P.; Fagherazzi, G.; Peeters, P.H.M.; Severi, G.; Hüsing, A. et al.
Source: Self-asserted source
Ioanna Tzoulaki via Scopus - Elsevier

Scientific Opinion on the setting of health-based reference values for metabolites of the active substance terbuthylazine

EFSA Journal
2019 | Journal article
DOI: 10.2903/j.efsa.2019.5712
EID:

2-s2.0-85068079145
Contributors: Hernandez-Jerez, A.F.; Adriaanse, P.; Aldrich, A.P.; Berny, P.; Duquesne, S.; Gimsing, A.L.; Millet, M.; Pelkonen, O.; Pieper, S.; Tiktak, A. et al.
Source: Self-asserted source
Ioanna Tzoulaki via Scopus - Elsevier

Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study

PLOS Medicine
2019-10-18 | Journal article
DOI: 10.1371/journal.pmed.1002937
Contributors: Xue Li; Kazem Rahimi; Xiangrui Meng; Yazhou He; Athina Spiliopoulou; Maria Timofeeva; Wei-Qi Wei; Aliya Gifford; Tian Yang; Tim Varley et al.
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Crossref

Serum metabolic signatures of coronary and carotid atherosclerosis and subsequent cardiovascular disease

European Heart Journal
2019-09-07 | Journal article
DOI: 10.1093/eurheartj/ehz235
Contributors: Ioanna Tzoulaki; Raphaële Castagné; Claire L Boulangé; Ibrahim Karaman; Elena Chekmeneva; Evangelos Evangelou; Timothy M D Ebbels; Manuja R Kaluarachchi; Marc Chadeau-Hyam; David Mosen et al.
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Crossref

GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits

Nature Communications
2019-08-13 | Journal article
DOI: 10.1038/s41467-019-11451-y
Contributors: Raha Pazoki; Evangelos Evangelou; David Mosen-Ansorena; Rui Climaco Pinto; Ibrahim Karaman; Paul Blakeley; Dipender Gill; Verena Zuber; Paul Elliott; Ioanna Tzoulaki et al.
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Crossref

Associations of genetically determined iron status across the phenome: A mendelian randomization study.

PLoS medicine
2019-06 | Journal article
DOI: 10.1371/journal.pmed.1002833
PMID: 31220083
PMC: PMC6586257
Contributors: Gill D; Benyamin B; Moore LSP; Monori G; Zhou A; Koskeridis F; Evangelou E; Laffan M; Walker AP; Tsilidis KK et al.
Source: Self-asserted source
Ioanna Tzoulaki via Europe PubMed Central
grade
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Circulating concentrations of micro-nutrients and risk of breast cancer: A Mendelian randomization study

2019-06 | Other
DOI: 10.1101/668186
OTHER-ID:

PPR82537
Contributors: Papadimitriou N; Dimou N; Gill D; Tzoulaki I; Murphy N; Riboli E; Lewis SJ; Martin RM; Gunter MJ; Tsilidis KK
Source: Self-asserted source
Ioanna Tzoulaki via Europe PubMed Central

Cortisol, Amyloid-β, and Reserve Predicts Alzheimer's Disease Progression for Cognitively Normal Older Adults.

Journal of Alzheimer's disease : JAD
2019-06 | Journal article
DOI: 10.3233/jad-181030
PMID: 31256117
Contributors: Udeh-Momoh CT; Su B; Evans S; Zheng B; Sindi S; Tzoulaki I; Perneczky R; Middleton LT; Alzheimer’s Disease Neuroimaging Initiative
Source: Self-asserted source
Ioanna Tzoulaki via Europe PubMed Central

The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies.

American journal of epidemiology
2019-06 | Journal article
DOI: 10.1093/aje/kwz028
PMID: 31155658
Contributors: Yu B; Zanetti KA; Temprosa M; Albanes D; Appel N; Barrera CB; Ben-Shlomo Y; Boerwinkle E; Casas JP; Clish C et al.
Source: Self-asserted source
Ioanna Tzoulaki via Europe PubMed Central
grade
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Use of Genetic Variants Related to Antihypertensive Drugs to Inform on Efficacy and Side Effects.

Circulation
2019-06 | Journal article
DOI: 10.1161/circulationaha.118.038814
PMID: 31234639
Contributors: Gill D; Georgakis MK; Koskeridis F; Jiang L; Feng Q; Wei WQ; Theodoratou E; Elliott P; Denny JC; Malik R et al.
Source: Self-asserted source
Ioanna Tzoulaki via Europe PubMed Central

A catalog of genetic loci associated with kidney function from analyses of a million individuals.

Nature genetics
2019-05 | Journal article
DOI: 10.1038/s41588-019-0407-x
PMID: 31152163
Contributors: Wuttke M; Li Y; Li M; Sieber KB; Feitosa MF; Gorski M; Tin A; Wang L; Chu AY; Hoppmann A et al.
Source: Self-asserted source
Ioanna Tzoulaki via Europe PubMed Central
grade
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A Phenome-wide Mendelian Randomisation study on genetically determined serum urate levels in UK Biobank cohort

2019-05 | Other
DOI: 10.1101/630293
OTHER-ID:

PPR78829
Contributors: Li X; Meng X; He Y; Spiliopoulou A; Timofeeva M; Wei W; Gifford A; Yang T; Varley T; Tzoulaki I et al.
Source: Self-asserted source
Ioanna Tzoulaki via Europe PubMed Central

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

Nature communications
2019-05 | Journal article
DOI: 10.1038/s41467-019-10160-w
PMID: 31043617
PMC: PMC6494826
Contributors: Davies G; Lam M; Harris SE; Trampush JW; Luciano M; Hill WD; Hagenaars SP; Ritchie SJ; Marioni RE; Fawns-Ritchie C et al.
Source: Self-asserted source
Ioanna Tzoulaki via Europe PubMed Central
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Importance of vitamin D in acute and critically ill children with subgroup analyses of sepsis and respiratory tract infections: a systematic review and meta-analysis

BMJ Open
2019-05 | Journal article
DOI: 10.1136/bmjopen-2018-027666
Contributors: Margarita Cariolou; Meghan A Cupp; Evangelos Evangelou; Ioanna Tzoulaki; Antonio J Berlanga-Taylor
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Metabolomics Profiling of Visceral Adipose Tissue: Results From MESA and the NEO Study.

Journal of the American Heart Association
2019-05 | Journal article
DOI: 10.1161/JAHA.118.010810
PMID: 31017036
PMC: PMC6512086
Contributors: Neeland IJ; Boone SC; Mook-Kanamori DO; Ayers C; Smit RAJ; Tzoulaki I; Karaman I; Boulange C; Vaidya D; Punjabi N et al.
Source: Self-asserted source
Ioanna Tzoulaki via Europe PubMed Central
grade
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Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study.

BMJ (Clinical research ed.)
2019-05 | Journal article
DOI: 10.1136/bmj.l1855
PMID: 31122926
PMC: PMC6529852
Contributors: Carter AR; Gill D; Davies NM; Taylor AE; Tillmann T; Vaucher J; Wootton RE; Munafò MR; Hemani G; Malik R et al.
Source: Self-asserted source
Ioanna Tzoulaki via Europe PubMed Central
grade
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Consumption of Meat, Fish, Dairy Products, and Eggs and Risk of Ischemic Heart Disease.

Circulation
2019-04 | Journal article
DOI: 10.1161/circulationaha.118.038813
PMID: 31006335
Contributors: Key TJ; Appleby PN; Bradbury KE; Sweeting M; Wood A; Johansson I; Kühn T; Steur M; Weiderpass E; Wennberg M et al.
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Ioanna Tzoulaki via Europe PubMed Central
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Peer review (16 reviews for 9 publications/grants)

Review activity for American journal of human genetics. (1)
Review activity for Cell genomics. (1)
Review activity for EBioMedicine. (1)
Review activity for Genome medicine. (1)
Review activity for Nature communications (5)
Review activity for Nature medicine. (4)
Review activity for Nature reviews methods primers. (1)
Review activity for npj digital medicine. (1)
Review activity for PLoS medicine. (1)
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