Markus Hafner

ORCID iD
https://orcid.org/0000-0002-4336-6518
  • Keywords
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Posttranscriptional Gene Regulation, RNA, RNAi, Aptamers

Sources:
Markus Hafner (2014-03-17)

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Lab Homepage

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Markus Hafner (2015-10-21)

Mendeley profile

Sources:
Elsevier - Mendeley (2018-03-16)

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Scopus Author ID: 23094493800

Sources:
Scopus - Elsevier (2014-03-17)

ResearcherID: O-7100-2018

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ResearcherID (2018-07-31)

Biography

I joined the Laboratory of Muscle Stem Cells and Gene Regulation as an Investigator in 2014. Before my appointment at NIAMS, I was a Postdoctoral Fellow in the Laboratory of Dr. Thomas Tuschl at the Rockefeller University in New York. There I worked on mechanisms of gene silencing by small RNAs, and developed methods to characterize posttranscriptional gene regulation by RNA binding proteins. I obtained a M.Sc. in Chemistry in 2002 and a Ph.D. in Biochemistry in 2007 from the University of Bonn, Germany. My graduate work under Dr. Michael Famulok focused on the use of RNA aptamers to select small molecule inhibitors for cytohesins, a family of guanosine exchange factors, which revealed their role in the insulin signaling pathway. In my own laboratory at NIAMS, I will focus on dissecting the composition of ribonucleoproteins (RNPs) involved in cellular RNA transport and control of RNA stability. This is a prerequisite for understanding the consequences of dysregulation and/or mutation of RNA-binding proteins (RBPs), and/or their target RNA-binding sites in disease.
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