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Upon completion of her doctorate in Medical Biochemistry & Molecular Biology [Thesis titled “Biochemical Studies Based on Signal Transduction by C-erbB-2 gene Product”, Laboratory of Breast and Ovarian Cancer Biology, Duke University Medical Center, Durham, NC, USA.], Dr. Samar Kamal Kassim at Ain Shams Faculty of Medicine directed research in basic cancer research. This led to the publication of many articles in cancer diagnosis and follow up (Eissa et al, 2011, Eissa et al, 2005, Kassim et al, 2004, Eissa et al, 2003 etc.) where she helped establishing detection systems for many epithelial cancers using tumor and genetic markers. At 2002, she joined Glasgow Caledonian University where she identified the differences between breast and ovarian cancers in the Androgen receptor gene methylation and exon one CAG repeat length (Kassim et al, 2004-2). Dr. Kassim also joined important research in molecular events accompanying hepatitis C viral infections among Egyptian patients, which led to the publications of many articles as (Hassan et al, 2007, and Hassan et al, 2002 etc.) She directed Bioinformatics research of breast cancer for the development of an Association system for breast cancer microarray (Darweesh et al, 2014). She also directed the presentation of An Ensemble Feature Extraction Classifier for the Analysis of Integrated Data of HCV-HCC Related DNA Microarray (Eid et al, 2014). This feature enables the prediction of hepatocellular carcinoma among chronic HCV infected patients. She published a large longitudinal study in the American Journal of Gastroenterology about the Host and viral determinants of the outcome of exposure to HCV infection genotype 4 (Kamal et al, 2014). Dr. Kassim helped the development of Bioinformatics Master and undergraduate programs in Helwan and Ain Shams Universities. She is the Co-PI of the Egyptian node of the H3ABioNet granted by the NIH through which published in Science Magazine (H3Africa consortium, 2014)”, Genome research (Mulder et al, 2015), and Global Heart (Mulder et al, 2017). She was the Co-Chair of the ECTWG of A3Africa since May 2016 till March 2018. ECTWG published their experience in designing and successfully delivering the eGenomic Medicine for African Medical and Paramedical professionals in Front Genet., 2019 (Nembaware V et al, 2019). Dr. Kassim contributed in the development of recommended Bioinformatics curricula by H3ABioNet. She Currently leads the Precision Medicine Portal Working group of H3ABioNet through which they published their first review article about Pharmacogenetics in African in Precision Medicine (Radouani et al, 2020). And lastly she contributed in Nature publication studying human migration in Africa (Choudhury A et al, 2020). Dr. Kassim currently leads the Computational Biology Team At MASRI Research Center of Ain Shams University and published with team two Science articles about Covid-19 in Africa.
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1U41HG006941-01 REVISED
5U24HG006941-08
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