Personal information

Crystallization, Process Development, Physical Chemistry, Technology development, Crystallography
Belgium

Activities

Employment (1)

Janssen Research and Development Belgium: Beerse, Antwerpen, BE

2012-04-01 to present | Principal Scientist (Chemical and Pharmaceutical Development & Supply)
Employment
Source: Self-asserted source
Alain Collas

Professional activities (1)

University of Antwerp: Antwerp, BE

2017-09-30 to present | Guest Lecturer (Chemistry)
Invited position
Source: Self-asserted source
Alain Collas

Works (30)

Charting the salt–cocrystal continuum of acid–base multicomponent crystals with hybrid density functional theory

CrystEngComm
2024 | Journal article
Contributors: Kristof M. Bal; Alain Collas
Source: check_circle
Crossref

Optimal Experimental Design for (Semi-)Batch Crystallization Processes

Computer Aided Chemical Engineering
2024 | Book chapter
Part of ISBN: 9780443288241
Part of ISSN: 1570-7946
Contributors: Gustavo L. Quilló; Wannes Mores; Satyajeet S. Bhonsale; Alain Collas; Christos Xiouras; Jan F.M. Van Impe
Source: Self-asserted source
Alain Collas

High PZT-power actuation for the separation of polydisperse glycine crystals at high flow rates and solid content using acoustophoresis

Chemical Engineering and Processing - Process Intensification
2024-08 | Journal article
Part of ISSN: 0255-2701
Contributors: antonio maisto; M. Bilgen; A. de Hemptinne; P. Gelin; M. Briet; R. Mertens; B. Gielen; A. Collas; W. De Malsche
Source: Self-asserted source
Alain Collas

Are Elastic Properties of Molecular Crystals within Reach of Density Functional Theory? Accuracy, Robustness, and Reproducibility of Current Approaches

Crystal Growth & Design
2024-05-01 | Journal article
Part of ISSN: 1528-7483
Part of ISSN: 1528-7505
Contributors: Kristof Bal; Alain Collas
Source: Self-asserted source
Alain Collas

Bottom-up production of injectable itraconazole suspensions using membrane technology

International Journal of Pharmaceutics
2024-04 | Journal article
Part of ISSN: 0378-5173
Contributors: Fatima Anjum; Thaïsa Viville; Snehashis Nandi; Maximilian Wessner; Bruno De Witte; Alain Collas; Gabriele Sadowski
Source: Self-asserted source
Alain Collas

Supercritical enhanced atomization induced particle entrapment for continuous production of injectable micro and nano-suspensions

Journal of CO2 Utilization
2024-03 | Journal article
Part of ISSN: 2212-9820
Contributors: Snehashis Nandi; Alain Collas; Lidia Tajber; Luis Padrela
Source: Self-asserted source
Alain Collas

Tailoring the use of excipients in bottom-up production of naproxen crystal suspensions via membrane technology

International Journal of Pharmaceutics
2024-03 | Journal article
Contributors: Fatima Anjum; Maximilian Wessner; Bruno De Witte; Noor Al-Rifai; Alain Collas; Gabriele Sadowski
Source: check_circle
Crossref

Continuous Microfluidic Antisolvent Crystallization as a Bottom-Up Solution for the Development of Long-Acting Injectable Formulations

Pharmaceutics
2024-03-08 | Journal article
Contributors: Snehashis Nandi; Laura Verstrepen; Mariana Hugo Silva; Luis Padrela; Lidia Tajber; Alain Collas
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Dynamic Optimization of Active Pharmaceutical Ingredient (Semi-)Batch Crystallization using Population Balance Modelling

Computer Aided Chemical Engineering
2023 | Book chapter
Part of ISBN: 9780443152740
Part of ISSN: 1570-7946
Contributors: Gustavo L. Quilló; Jan F.M. Van Impe; Alain Collas; Christos Xiouras; Satyajeet S. Bhonsale
Source: Self-asserted source
Alain Collas
grade
Preferred source (of 2)‎

Development of long-acting injectable suspensions by continuous antisolvent crystallization: An integrated bottom-up process

International Journal of Pharmaceutics
2023-12 | Journal article
Contributors: Snehashis Nandi; Luis Padrela; Lidia Tajber; Alain Collas
Source: check_circle
Crossref

Nucleation kinetics-based solvent selection for the liquid antisolvent crystallization of a lipophilic intermediate

Journal of Molecular Liquids
2023-04 | Journal article
Part of ISSN: 0167-7322
Contributors: Snehashis Nandi; Luis Padrela; Lidia Tajber; Alain Collas
Source: Self-asserted source
Alain Collas

Iterative model-based optimal experimental design for mixture-process variable models to predict solubility

Chemical Engineering Research and Design
2023-01 | Journal article
Contributors: Gustavo Lunardon Quilló; Satyajeet Bhonsale; Alain Collas; Christos Xiouras; Jan F.M. Van Impe
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Crystal Growth Kinetics of an Industrial Active Pharmaceutical Ingredient: Implications of Different Representations of Supersaturation and Simultaneous Growth Mechanisms

Crystal Growth & Design
2021-09-01 | Journal article
Part of ISSN: 1528-7483
Part of ISSN: 1528-7505
Source: Self-asserted source
Alain Collas

Finding polar crystal structures: molecular structures, intermolecular interactions and unit-cell dipoles

Acta Crystallographica Section A Foundations and Advances
2018-08-22 | Journal article
Part of ISSN: 2053-2733
Contributors: Frank Blockhuys; Jasper Van de Velde; Alain Collas
Source: Self-asserted source
Alain Collas

Twin Tandem Bicycle Pedal Motion - Using X-rays to Resolve Disorder Thermodynamic Parameters

Acta Crystallographica Section A Foundations and Advances
2014-08-05 | Journal article
Part of ISSN: 2053-2733
Contributors: Christophe Vande Velde; Alain Collas; Matthias Zeller; Frank Blockhuys
Source: Self-asserted source
Alain Collas

(E)-4-[2-(3,4,5-Trimethoxyphenyl)-ethenyl]nitrobenzene and its 'bridgeflipped' analogues

Acta Crystallographica Section C: Crystal Structure Communications
2011 | Journal article
EID:

2-s2.0-80052492385

Part of ISBN:

01082701 16005759

Contributors: Collas, A.; Blockhuys, F.
Source: Self-asserted source
Alain Collas via Scopus - Elsevier

(E,E)-N <sup>1</sup>-(2,3,4,5,6-Pentafluorobenzylidene)-N <sup>4</sup>-(3,4,5-trimethoxybenzylidene)benzene-1,4-diamine

Acta Crystallographica Section E: Structure Reports Online
2011 | Journal article
EID:

2-s2.0-83155189191

Part of ISBN:

16005368

Contributors: Collas, A.; Blockhuys, F.
Source: Self-asserted source
Alain Collas via Scopus - Elsevier

4,4′-Bis[2-(3,5-dimethoxyphenyl)-ethenyl]biphenyl

Acta Crystallographica Section E: Structure Reports Online
2011 | Journal article
EID:

2-s2.0-79955582781

Part of ISBN:

16005368 16005368

Contributors: Collas, A.; Zeller, M.; Blockhuys, F.
Source: Self-asserted source
Alain Collas via Scopus - Elsevier

Activation and de-activation of fluorine synthons by nitrogen substitution in fluorinated aza-distyrylbenzenes

CrystEngComm
2011 | Journal article
EID:

2-s2.0-78650406936

Part of ISBN:

14668033 14668033

Contributors: Collas, A.; De Borger, R.; Amanova, T.; Blockhuys, F.
Source: Self-asserted source
Alain Collas via Scopus - Elsevier

Asymmetrically substituted distyrylbenzenes and their polar crystal structures

New Journal of Chemistry
2011 | Journal article
EID:

2-s2.0-79952210345

Part of ISBN:

13699261 11440546

Contributors: Collas, A.; Borger, R.D.; Amanova, T.; Vande Velde, C.M.L.; Baeke, J.K.; Dommisse, R.; Alsenoy, C.V.; Blockhuys, F.
Source: Self-asserted source
Alain Collas via Scopus - Elsevier

Competition between methoxy-based and pyrazine-based synthons in methoxy-substituted distyrylpyrazines

Crystal Growth and Design
2011 | Journal article
EID:

2-s2.0-79953873139

Part of ISBN:

15287483 15287505

Contributors: Collas, A.; Bagrowska, I.; Aleksandrzak, K.; Zeller, M.; Blockhuys, F.
Source: Self-asserted source
Alain Collas via Scopus - Elsevier

Conformational polymorphism of (E,E)-N,N′-bis-(4-nitrobenzylidene) benzene-1,4-diamine

Acta Crystallographica Section C: Crystal Structure Communications
2011 | Journal article
EID:

2-s2.0-79955588811

Part of ISBN:

01082701 01082701

Contributors: Collas, A.; Zeller, M.; Blockhuys, F.
Source: Self-asserted source
Alain Collas via Scopus - Elsevier
grade
Preferred source (of 2)‎

Dynamic disorder in the crystal structure of an organic semiconductor: An unusual phase transition involving the heat capacity

Chemistry - A European Journal
2011 | Journal article
EID:

2-s2.0-78651429351

Part of ISBN:

09476539 15213765

Contributors: Vande Velde, C.M.L.; Collas, A.; De Borger, R.; Blockhuys, F.
Source: Self-asserted source
Alain Collas via Scopus - Elsevier

(E)-1-(2,4,6-Trimethoxyphenyl)pent-1-en-3-one

Acta Crystallographica Section E: Structure Reports Online
2010 | Journal article
EID:

2-s2.0-77957836423

Part of ISBN:

16005368 16005368

Contributors: Collas, A.; Blockhuys, F.
Source: Self-asserted source
Alain Collas via Scopus - Elsevier

2-(4-Formyl-2,6-dimeth-oxy-phenoxy)-acetic acid

Acta Crystallographica Section E: Structure Reports Online
2010 | Journal article
EID:

2-s2.0-78650947288

Part of ISBN:

16005368 16005368

Contributors: Collas, A.; Vande Velde, C.M.L.; Blockhuys, F.
Source: Self-asserted source
Alain Collas via Scopus - Elsevier

3-(2-Formylphenoxy)propanoic acid

Acta Crystallographica Section E: Structure Reports Online
2010 | Journal article
EID:

2-s2.0-77957840182

Part of ISBN:

16005368 16005368

Contributors: Collas, A.; Vande Velde, C.M.L.; Blockhuys, F.
Source: Self-asserted source
Alain Collas via Scopus - Elsevier

4-[(E)-2-(2,4,6-Trinitrophenyl)ethylidene]benzonitrile

Acta Crystallographica Section E: Structure Reports Online
2010 | Journal article
EID:

2-s2.0-77957852893

Part of ISBN:

16005368 16005368

Contributors: De Borger, R.; Collas, A.; Blockhuys, F.
Source: Self-asserted source
Alain Collas via Scopus - Elsevier

Synthesis and structures of substituted triphen-yl(phenyl-imino)phospho- ranes

Acta Crystallographica Section C: Crystal Structure Communications
2010 | Journal article
EID:

2-s2.0-74049149178

Part of ISBN:

01082701 01082701

Contributors: De Borger, R.; Collas, A.; Dommisse, R.; Blockhuys, F.
Source: Self-asserted source
Alain Collas via Scopus - Elsevier

Functionalized analogues of Tröger's base: scope and limitations of a general synthetic procedure and facile, predictable method for the separation of enantiomers

Tetrahedron
2008 | Journal article
EID:

2-s2.0-44349106975

Part of ISBN:

00404020

Contributors: Didier, D.; Tylleman, B.; Lambert, N.; Vande Velde, C.M.L.; Blockhuys, F.; Collas, A.; Sergeyev, S.
Source: Self-asserted source
Alain Collas via Scopus - Elsevier

Molecular structures of two E-azobenzocrown ethers

Journal of Molecular Structure
2008 | Journal article
EID:

2-s2.0-55749094688

Part of ISBN:

00222860

Contributors: Fonari, M.S.; Luboch, E.; Collas, A.; Bukrej, A.; Blockhuys, F.; Biernat, J.F.
Source: Self-asserted source
Alain Collas via Scopus - Elsevier