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Institut Pasteur: Paris, FR

2008 to present | Principal Investigator
Employment
Source: Self-asserted source
Marco Vignuzzi

Works (50 of 76)

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IRF8 regulates efficacy of therapeutic anti‐CD20 monoclonal antibodies

European Journal of Immunology
2022-10 | Journal article
DOI: 10.1002/eji.202250037
Contributors: Ludivine Grzelak; Ferdinand Roesch; Amaury Vaysse; Anne Biton; Rachel Legendre; Françoise Porrot; Pierre‐Henri Commère; Cyril Planchais; Hugo Mouquet; Marco Vignuzzi et al.
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Crossref

Chemical Evolution of Rhinovirus Identifies Capsid-Destabilizing Mutations Driving Low-pH-Independent Genome Uncoating

Journal of Virology
2022-01-26 | Journal article
DOI: 10.1128/JVI.01060-21
Contributors: Luca Murer; Anthony Petkidis; Thomas Vallet; Marco Vignuzzi; Urs F. Greber; Bryan R. G. Williams
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Crossref

Herpes Simplex Virus Type 1 Infection Disturbs the Mitochondrial Network, Leading to Type I Interferon Production through the RNA Polymerase III/RIG-I Pathway

mBio
2021-12-21 | Journal article
DOI: 10.1128/mBio.02557-21
Contributors: Noémie Berry; Rodolphe Suspène; Vincent Caval; Pierre Khalfi; Guillaume Beauclair; Stéphane Rigaud; Hervé Blanc; Marco Vignuzzi; Simon Wain-Hobson; Jean-Pierre Vartanian et al.
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Crossref

Intra- and Inter-cellular Modeling of Dynamic Interaction between Zika Virus and Its Naturally Occurring Defective Viral Genomes

Journal of Virology
2021-10-27 | Journal article
DOI: 10.1128/JVI.00977-21
Contributors: Vadim Sharov; Veronica V. Rezelj; Vladimir V. Galatenko; Avi Titievsky; Julia Panov; Konstantin Chumakov; Raul Andino; Marco Vignuzzi; Leonid Brodsky; Rebecca Ellis Dutch
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Crossref

A virus-encoded microRNA contributes to evade innate immune response during SARS-CoV-2 infection

2021-09-09 | Other
DOI: 10.1101/2021.09.09.459577
Contributors: Meetali Singh; Maxime Chazal; Piergiuseppe Quarato; Loan Bourdon; Christophe Malabat; Thomas Vallet; Marco Vignuzzi; Sylvie van der Werf; Sylvie Behillil; Flora Donati et al.
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Crossref

Exploring zebrafish larvae as a COVID-19 model: probable SARS-COV-2 replication in the swim bladder

2021-04-10 | Preprint
DOI: 10.1101/2021.04.08.439059
Contributors: Valerio Laghi; Veronica Rezelj; Laurent Boucontet; Maxence Frétaud; Bruno da Costa; Pierre Boudinot; Irene Salinas; Georges Lutfalla; Marco Vignuzzi; Jean-Pierre Levraud
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Crossref

Characterisation of protease activity during SARS-CoV-2 infection identifies novel viral cleavage sites and cellular targets for drug repurposing

2020-09-16 | Other
DOI: 10.1101/2020.09.16.297945
Contributors: Bjoern Meyer; Jeanne Chiaravalli; Philip Brownridge; Dominic P. Bryne; Leonard A. Daly; Fabrice Agou; Claire E. Eyers; Patrick A. Eyers; Marco Vignuzzi; Edward Emmott
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Crossref

Modelling Degradation and Replication Kinetics of the Zika Virus In Vitro Infection

Viruses
2020-05-15 | Journal article
DOI: 10.3390/v12050547
Contributors: Veronika Bernhauerová; Veronica V. Rezelj; Marco Vignuzzi
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Crossref

Chikungunya Virus Vaccine Candidates with Decreased Mutational Robustness Are Attenuated In Vivo and Have Compromised Transmissibility

Journal of Virology
2019-09-15 | Journal article
DOI: 10.1128/JVI.00775-19
Contributors: Lucía Carrau; Veronica V. Rezelj; María G. Noval; Laura I. Levi; Daniela Megrian; Herve Blanc; James Weger-Lucarelli; Gonzalo Moratorio; Kenneth A. Stapleford; Marco Vignuzzi et al.
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Crossref

Usutu Virus: An Arbovirus on the Rise

Viruses
2019-07-12 | Journal article
DOI: 10.3390/v11070640
Contributors: Ferdinand Roesch; Alvaro Fajardo; Gonzalo Moratorio; Marco Vignuzzi
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Crossref

Defective viral genomes are key drivers of the virus–host interaction

Nature Microbiology
2019-06-03 | Journal article
DOI: 10.1038/s41564-019-0465-y
Contributors: Marco Vignuzzi; Carolina B. López
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Crossref

Modeling cell infection via virus-producing cells rather than free infectious virus significantly improves fits of in vitro viral kinetic data

2019-05-05 | Other
DOI: 10.1101/627968
Contributors: Veronika Bernhauerová; Veronica V. Rezelj; Laura I. Levi; Marco Vignuzzi
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Crossref

Differential Transmission of Antiviral Drug-Resistant Chikungunya Viruses by Aedes Mosquitoes

mSphere
2018-08-29 | Journal article
DOI: 10.1128/mSphere.00230-18
Contributors: Leen Delang; Pei-Shi Yen; Thomas Vallet; Marie Vazeille; Marco Vignuzzi; Anna-Bella Failloux; Christina F. Spiropoulou
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Crossref

Monitoring and redirecting virus evolution

PLOS Pathogens
2018-06-07 | Journal article
DOI: 10.1371/journal.ppat.1006979
Contributors: Gonzalo Moratorio; Matthew J. Evans; Marco Vignuzzi
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Crossref

Complete Genome Sequence of a Novel Recombinant Citrus Tristeza Virus , a Resistance-Breaking Isolate from Uruguay

Genome Announcements
2018-05-31 | Journal article
DOI: 10.1128/genomeA.00442-18
Contributors: María José Benítez-Galeano; Thomas Vallet; Lucía Carrau; Lester Hernández-Rodríguez; Ana Bertalmío; Fernando Rivas; Leticia Rubio; Diego Maeso; Marco Vignuzzi; Gonzalo Moratorio et al.
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Crossref

Long term context dependent genetic adaptation of the viral genetic cloud

2018-02-12 | Other
DOI: 10.1101/262345
Contributors: Tzipi Klein; Antonio V. Bordería; Cyril Barbezange; Marco Vignuzzi; Yoram Louzoun
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Crossref

Chikungunya virus evolution following a large 3′UTR deletion results in host-specific molecular changes in protein-coding regions

Virus Evolution
2018-01-01 | Journal article
DOI: 10.1093/ve/vey012
Contributors: Valerie J Morley; María Gabriela Noval; Rubing Chen; Scott C Weaver; Marco Vignuzzi; Kenneth A Stapleford; Paul E Turner
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Crossref

Polyamines and Their Role in Virus Infection

Microbiology and Molecular Biology Reviews
2017-12 | Journal article
DOI: 10.1128/MMBR.00029-17
Contributors: Bryan C. Mounce; Michelle E. Olsen; Marco Vignuzzi; John H. Connor
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Crossref

Drivers of Dengue Intrahost Evolution.

Cell host & microbe
2017-09 | Journal article
DOI: 10.1016/j.chom.2017.08.015
PMID: 28910632
Contributors: Simon-Lorière E; Vignuzzi M
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

The Bridges and Blockades to Evolutionary Convergence on the Road to Predicting Chikungunya Virus Evolution.

Annual review of virology
2017-09 | Journal article
DOI: 10.1146/annurev-virology-101416-041757
PMID: 28961411
Contributors: Vignuzzi M; Higgs S
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Chikungunya Virus Overcomes Polyamine Depletion by Mutation of nsP1 and the Opal Stop Codon To Confer Enhanced Replication and Fitness

Journal of Virology
2017-08 | Journal article
DOI: 10.1128/JVI.00344-17
Contributors: Bryan C. Mounce; Teresa Cesaro; Lea Vlajnić; Anna Vidiņa; Thomas Vallet; James Weger-Lucarelli; Gabriella Passoni; Kenneth A. Stapleford; Jean-Pierre Levraud; Marco Vignuzzi et al.
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Crossref

Imaging of viral neuroinvasion in the zebrafish reveals that Sindbis and chikungunya viruses favour different entry routes.

Disease models & mechanisms
2017-07 | Journal article
DOI: 10.1242/dmm.029231
PMID: 28483796
PMC: PMC5536907
Contributors: Passoni G; Langevin C; Palha N; Mounce BC; Briolat V; Affaticati P; De Job E; Joly JS; Vignuzzi M; Saleh MC et al.
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Pathogenic Events in a Nonhuman Primate Model of Oral Poliovirus Infection Leading to Paralytic Poliomyelitis.

Journal of virology
2017-07 | Journal article
DOI: 10.1128/jvi.02310-16
PMID: 28356537
PMC: PMC5487571
Contributors: Shen L; Chen CY; Huang D; Wang R; Zhang M; Qian L; Zhu Y; Zhang AZ; Yang E; Qaqish A et al.
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Attenuation of RNA viruses by redirecting their evolution in sequence space.

Nature microbiology
2017-06 | Journal article
DOI: 10.1038/nmicrobiol.2017.88
PMID: 28581455
Contributors: Moratorio G; Henningsson R; Barbezange C; Carrau L; Bordería AV; Blanc H; Beaucourt S; Poirier EZ; Vallet T; Boussier J et al.
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Curcumin inhibits Zika and chikungunya virus infection by inhibiting cell binding.

Antiviral research
2017-06 | Journal article
DOI: 10.1016/j.antiviral.2017.03.014
PMID: 28343845
Contributors: Mounce BC; Cesaro T; Carrau L; Vallet T; Vignuzzi M
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Uptake and metabolism of arginine impact Plasmodium development in the liver.

Scientific reports
2017-06 | Journal article
DOI: 10.1038/s41598-017-04424-y
PMID: 28642498
PMC: PMC5481400
Contributors: Meireles P; Mendes AM; Aroeira RI; Mounce BC; Vignuzzi M; Staines HM; Prudêncio M
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Understanding the Mechanism of the Broad-Spectrum Antiviral Activity of Favipiravir (T-705): Key Role of the F1 Motif of the Viral Polymerase

Journal of Virology
2017-06-15 | Journal article
DOI: 10.1128/JVI.00487-17
Contributors: Rana Abdelnabi; Ana Theresa Silveira de Morais; Pieter Leyssen; Isabelle Imbert; Stéphanie Beaucourt; Hervé Blanc; Mathy Froeyen; Marco Vignuzzi; Bruno Canard; Johan Neyts et al.
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Crossref

Virus population dynamics during infection.

Current opinion in virology
2017-04 | Journal article
DOI: 10.1016/j.coviro.2017.03.013
PMID: 28456056
Contributors: Poirier EZ; Vignuzzi M
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Cell-Based High-Throughput Screening Assay Identifies 2',2'-Difluoro-2'-deoxycytidine Gemcitabine as a Potential Antipoliovirus Agent.

ACS infectious diseases
2017-01 | Journal article
DOI: 10.1021/acsinfecdis.6b00116
PMID: 27733043
PMC: PMC5754216
Contributors: Zhang Z; Yang E; Hu C; Cheng H; Chen CY; Huang D; Wang R; Zhao Y; Rong L; Vignuzzi M et al.
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly and p53.

Cell death & disease
2017-01 | Journal article
DOI: 10.1038/cddis.2016.446
PMID: 28102842
PMC: PMC5386363
Contributors: Ghouzzi VE; Bianchi FT; Molineris I; Mounce BC; Berto GE; Rak M; Lebon S; Aubry L; Tocco C; Gai M et al.
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Fidelity Variants and RNA Quasispecies.

Current topics in microbiology and immunology
2016 | Journal article
PMID: 26499340
Contributors: Bordería AV; Rozen-Gagnon K; Vignuzzi M
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Virus-derived DNA drives mosquito vector tolerance to arboviral infection.

Nature communications
2016 | Journal article
DOI: 10.1038/ncomms12410
PMID: 27580708
PMC: PMC5025746
Contributors: Goic B; Stapleford KA; Frangeul L; Doucet AJ; Gausson V; Blanc H; Schemmel-Jofre N; Cristofari G; Lambrechts L; Vignuzzi M et al.
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Large-Scale Phylogenomic Analysis Reveals the Complex Evolutionary History of Rabies Virus in Multiple Carnivore Hosts.

PLoS pathogens
2016-12 | Journal article
DOI: 10.1371/journal.ppat.1006041
PMID: 27977811
PMC: PMC5158080
Contributors: Troupin C; Dacheux L; Tanguy M; Sabeta C; Blanc H; Bouchier C; Vignuzzi M; Duchene S; Holmes EC; Bourhy H
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Inhibition of Polyamine Biosynthesis Is a Broad-Spectrum Strategy against RNA Viruses.

Journal of virology
2016-11 | Journal article
DOI: 10.1128/jvi.01347-16
PMID: 27535047
PMC: PMC5068521
Contributors: Mounce BC; Cesaro T; Moratorio G; Hooikaas PJ; Yakovleva A; Werneke SW; Smith EC; Poirier EZ; Simon-Loriere E; Prot M et al.
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly and p53.

Cell death & disease
2016-10 | Journal article
DOI: 10.1038/cddis.2016.266
PMID: 27787521
PMC: PMC5133962
Contributors: Ghouzzi VE; Bianchi FT; Molineris I; Mounce BC; Berto GE; Rak M; Lebon S; Aubry L; Tocco C; Gai M et al.
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Homology-Based Identification of a Mutation in the Coronavirus RNA-Dependent RNA Polymerase That Confers Resistance to Multiple Mutagens.

Journal of virology
2016-08 | Journal article
DOI: 10.1128/jvi.00080-16
PMID: 27279608
PMC: PMC4984655
Contributors: Sexton NR; Smith EC; Blanc H; Vignuzzi M; Peersen OB; Denison MR
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Interferon-Induced Spermidine-Spermine Acetyltransferase and Polyamine Depletion Restrict Zika and Chikungunya Viruses.

Cell host & microbe
2016-08 | Journal article
DOI: 10.1016/j.chom.2016.06.011
PMID: 27427208
Contributors: Mounce BC; Poirier EZ; Passoni G; Simon-Loriere E; Cesaro T; Prot M; Stapleford KA; Moratorio G; Sakuntabhai A; Levraud JP et al.
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.

The Journal of biological chemistry
2016-07 | Journal article
DOI: 10.1074/jbc.m116.726596
PMID: 27137934
PMC: PMC4933160
Contributors: McDonald S; Block A; Beaucourt S; Moratorio G; Vignuzzi M; Peersen OB
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Increasing Clinical Severity during a Dengue Virus Type 3 Cuban Epidemic: Deep Sequencing of Evolving Viral Populations.

Journal of virology
2016-05 | Journal article
DOI: 10.1128/jvi.02647-15
PMID: 26889031
PMC: PMC4836355
Contributors: Rodriguez-Roche R; Blanc H; Bordería AV; Díaz G; Henningsson R; Gonzalez D; Santana E; Alvarez M; Castro O; Fontes M et al.
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Increasing Clinical Severity during a Dengue Virus Type 3 Cuban Epidemic: Deep Sequencing of Evolving Viral Populations

OpenAlex
2016-05-01 | Other
DOI: 10.60692/j3y2f-mfb31
Contributors: Rosmari Rodríguez‐Roche; Hervé Blanc; Antonio V. Bordería; Gisell Díaz; Rasmus Henningsson; Daniel Gonzalez; Emidalys Santana; Mayling Álvarez; Osvaldo Castro; Márcia Fontes et al.
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DataCite

Increasing Clinical Severity during a Dengue Virus Type 3 Cuban Epidemic: Deep Sequencing of Evolving Viral Populations

OpenAlex
2016-05-01 | Other
DOI: 10.60692/371m8-p3192
Contributors: Rosmari Rodríguez‐Roche; Hervé Blanc; Antonio V. Bordería; Gisell Díaz; Rasmus Henningsson; Daniel Gonzalez; Emidalys Santana; Mayling Álvarez; Osvaldo Castro; Márcia Fontes et al.
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DataCite

Low-Fidelity Polymerases of Alphaviruses Recombine at Higher Rates To Overproduce Defective Interfering Particles.

Journal of virology
2016-03 | Journal article
DOI: 10.1128/jvi.02921-15
PMID: 26676773
PMC: PMC4810721
Contributors: Poirier EZ; Mounce BC; Rozen-Gagnon K; Hooikaas PJ; Stapleford KA; Moratorio G; Vignuzzi M
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Whole-Genome Sequencing Analysis from the Chikungunya Virus Caribbean Outbreak Reveals Novel Evolutionary Genomic Elements.

PLoS neglected tropical diseases
2016-01 | Journal article
DOI: 10.1371/journal.pntd.0004402
PMID: 26807575
PMC: PMC4726740
Contributors: Stapleford KA; Moratorio G; Henningsson R; Chen R; Matheus S; Enfissi A; Weissglas-Volkov D; Isakov O; Blanc H; Mounce BC et al.
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Inhibition of mTORC1 Enhances the Translation of Chikungunya Proteins via the Activation of the MnK/eIF4E Pathway.

2015-08 | Journal article
DOI: 10.1371/journal.ppat.1005091
PMID: 26317997
PMC: PMC4552638
Contributors: Joubert PE; Stapleford K; Guivel-Benhassine F; Vignuzzi M; Schwartz O; Albert ML
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Interdisciplinarity and Infectious Diseases: An Ebola Case Study.

2015-08 | Journal article
DOI: 10.1371/journal.ppat.1004992
PMID: 26247831
PMC: PMC4527690
Contributors: Ezenwa VO; Prieur-Richard AH; Roche B; Bailly X; Becquart P; García-Peña GE; Hosseini PR; Keesing F; Rizzoli A; Suzán G et al.
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Viral polymerase-helicase complexes regulate replication fidelity to overcome intracellular nucleotide depletion.

2015-08 | Journal article
PMID: 26311883
Contributors: Stapleford KA; Rozen-Gagnon K; Das PK; Saul S; Poirier EZ; Blanc H; Vidalain PO; Merits A; Vignuzzi M
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Deep sequencing analysis of viral infection and evolution allows rapid and detailed characterization of viral mutant spectrum.

2015-07 | Journal article
DOI: 10.1093/bioinformatics/btv101
PMID: 25701575
PMC: PMC4481840
Contributors: Isakov O; Bordería AV; Golan D; Hamenahem A; Celniker G; Yoffe L; Blanc H; Vignuzzi M; Shomron N
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Mutations in coronavirus nonstructural protein 10 decrease virus replication fidelity.

2015-06 | Journal article
DOI: 10.1128/JVI.00110-15
PMID: 25855750
Contributors: Smith EC; Case JB; Blanc H; Isakov O; Shomron N; Vignuzzi M; Denison MR
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Group Selection and Contribution of Minority Variants during Virus Adaptation Determines Virus Fitness and Phenotype.

2015-05 | Journal article
DOI: 10.1371/journal.ppat.1004838
PMID: 25941809
PMC: PMC4420505
Contributors: Bordería AV; Isakov O; Moratorio G; Henningsson R; Agüera-González S; Organtini L; Gnädig NF; Blanc H; Alcover A; Hafenstein S et al.
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central

Structure-function relationships underlying the replication fidelity of viral RNA-dependent RNA polymerases.

2015-01 | Journal article
DOI: 10.1128/JVI.01574-14
PMID: 25320316
PMC: PMC4301111
Contributors: Campagnola G; McDonald S; Beaucourt S; Vignuzzi M; Peersen OB
Source: Self-asserted source
Marco Vignuzzi via Europe PubMed Central
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