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University Hospital Frankfurt: Frankfurt am Main, DE

2022-12-15 to present | Group Leader (Dr. Senckenbergisches Institut für Neuroonkologie)
Employment
Source: Self-asserted source
Ann-Christin Hau

Works (28)

Federated learning enables big data for rare cancer boundary detection.

Nature communications
2022-12 | Journal article
DOI: 10.1038/s41467-022-33407-5
PMID: 36470898
PMC: PMC9722782
Contributors: Pati S; Baid U; Edwards B; Sheller M; Wang SH; Reina GA; Foley P; Gruzdev A; Karkada D; Davatzikos C et al.
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

Glioma progression is shaped by genetic evolution and microenvironment interactions.

Cell
2022-05 | Journal article
DOI: 10.1016/j.cell.2022.04.038
PMID: 35649412
Contributors: Varn FS; Johnson KC; Martinek J; Huse JT; Nasrallah MP; Wesseling P; Cooper LAD; Malta TM; Wade TE; Sabedot TS et al.
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

EPCO-13. MULTIOMIC SINGLE NUCLEUS RNA- AND ATACseq PROFILING REVEALS REGULATORS OF GLIOMA CELL STATE DIVERSITY

Neuro-oncology
2021-11 | Journal article
PMC: PMC8598809
Contributors: Anderson K; Johnson K; Varn F; Bessonett S; Gujar A; Flynn B; Courtois E; Hau A; Golebiewska A; Paek S et al.
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

Transcriptional cooperation of PBX1 and PAX6 in adult neural progenitor cells.

Scientific reports
2021-10 | Journal article
DOI: 10.1038/s41598-021-99968-5
PMID: 34697387
PMC: PMC8545929
Contributors: Hau AC; Mommaerts E; Laub V; Müller T; Dittmar G; Schulte D
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

The epigenetic evolution of gliomas is determined by their IDH1 mutation status and treatment regimen

2021-08 | Preprint
DOI: 10.1101/2021.08.09.455687
PPR: PPR381486
Contributors: Malta TM; Sabedot TS; Datta I; Garofano L; Vallentgoed W; Varn FS; Aldape K; D’Angelo F; Bakas S; Barnholtz-Sloan JS et al.
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

Protocol for derivation of organoids and patient-derived orthotopic xenografts from glioma patient tumors.

STAR protocols
2021-05 | Journal article
DOI: 10.1016/j.xpro.2021.100534
PMID: 34027491
PMC: PMC8132120
Contributors: Oudin A; Baus V; Barthelemy V; Fabian C; Klein E; Dieterle M; Wantz M; Hau AC; Dording C; Bernard A et al.
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

FSMP-07. CYSTATHIONINE-Γ-LYASE DRIVES ANTIOXIDANT DEFENSE IN CYSTEINE-RESTRICTED IDH1 MUTANT ASTROCYTOMAS

Neuro-oncology advances
2021-03 | Journal article
PMC: PMC7992224
Contributors: Cano-Galiano A; Oudin A; Fack F; Allega M; Sumpton D; Martinez-Garcia E; Dittmar G; Hau A; Herold-Mende C; Bjerkvig R et al.
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

Cystathionine-γ-lyase drives antioxidant defense in cysteine-restricted IDH1-mutant astrocytomas.

Neuro-oncology advances
2021-01 | Journal article
DOI: 10.1093/noajnl/vdab057
PMID: 34250481
PMC: PMC8262642
Contributors: Cano-Galiano A; Oudin A; Fack F; Allega MF; Sumpton D; Martinez-Garcia E; Dittmar G; Hau AC; De Falco A; Herold-Mende C et al.
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion.

Nature communications
2020-12 | Journal article
DOI: 10.1038/s41467-020-20029-y
PMID: 33311477
PMC: PMC7732990
Contributors: Schuster A; Klein E; Neirinckx V; Knudsen AM; Fabian C; Hau AC; Dieterle M; Oudin A; Nazarov PV; Golebiewska A et al.
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

Glioblastoma Organoids: Pre-Clinical Applications and Challenges in the Context of Immunotherapy.

Frontiers in oncology
2020-12 | Journal article
DOI: 10.3389/fonc.2020.604121
PMID: 33364198
PMC: PMC7753120
Contributors: Klein E; Hau AC; Oudin A; Golebiewska A; Niclou SP
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

TMOD-08. PRIMARY AND RECURRENT GLIOMA PATIENT-DERIVED ORTHOTOPIC XENOGRAFTS (PDOX) REPRESENT RELEVANT PATIENT AVATARS FOR PRECISION MEDICINE

Neuro-oncology
2020-11 | Journal article
PMC: PMC7650928
Contributors: Golebiewska A; Hau A; Oudin A; Stieber D; Yabo Y; Kwon Y; Klink B; Skupin A; Hertel F; Bjerkvig R et al.
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.

Acta neuropathologica
2020-10 | Journal article
DOI: 10.1007/s00401-020-02226-7
PMID: 33009951
PMC: PMC7666297
Contributors: Golebiewska A; Hau AC; Oudin A; Stieber D; Yabo YA; Baus V; Barthelemy V; Klein E; Bougnaud S; Keunen O et al.
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

Primary and recurrent glioma patient-derived orthotopic xenografts (PDOX) represent relevant patient avatars for precision medicine

2020-04 | Preprint
DOI: 10.1101/2020.04.24.057802
PPR: PPR155275
Contributors: Golebiewska A; Hau A; Oudin A; Stieber D; Yabo YA; Baus V; Barthelemy V; Klein E; Bougnaud S; Keunen O et al.
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

CSIG-04. PAN-RTK INHIBITION OF sLRIG1 MEDIATES AXL DOWNREGULATION IN GLIOBLASTOMA

Neuro-oncology
2019-11 | Journal article
PMC: PMC6847328
Contributors: Neirinckx V; Hau A; Schuster A; Fritah S; Chevigné A; Schmidt M; Niclou S
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

GENE-02. ESTABLISHING PERSONALIZED TREATMENT OPTIONS FOR RECURRENT HIGH-GRADE GLIOMAS

Neuro-oncology
2019-11 | Journal article
PMC: PMC6847775
Contributors: Hau A; Houben L; Klein E; Oudin A; Stieber D; Flies B; Kaoma T; Azuaje F; Fritah S; Bjerkvig R et al.
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

OS12.2 Targeting epigenetic pathways in the treatment of recurrent high-grade glioma

Neuro-oncology
2019-09 | Journal article
PMC: PMC6795588
Contributors: Hau A; Houben L; Klein E; Oudin A; Stieber D; Flies B; Kaoma T; Azuaje F; Fritah S; Bjerkvig R et al.
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

P11.09 Pan-RTK inhibition of sLRIG1 mediates AXL downregulation in Glioblastoma

Neuro-oncology
2019-09 | Journal article
PMC: PMC6796174
Contributors: Neirinckx V; Hau A; Schuster A; Fritah S; Chevigné A; Schmidt M; Niclou S
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

The soluble form of pan-RTK inhibitor and tumor suppressor LRIG1 mediates downregulation of AXL through direct protein-protein interaction in glioblastoma.

Neuro-oncology advances
2019-05 | Journal article
DOI: 10.1093/noajnl/vdz024
PMID: 32642659
PMC: PMC7212925
Contributors: Neirinckx V; Hau AC; Schuster A; Fritah S; Tiemann K; Klein E; Nazarov PV; Matagne A; Szpakowska M; Meyrath M et al.
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

CADD-33. PERSONALIZED PHARMACOGENOMICS USING GLIOMA PATIENT-DERIVED ORTHOTOPIC XENOGRAFTS (PDOXS)

Neuro-oncology
2018-11 | Journal article
PMC: PMC6216873
Contributors: Hau A; Golebiewska A; Oudin A; Houben L; Stieber D; Hertel F; Niclou S
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

TMOD-29. MOLECULAR CHARACTERIZATION OF GLIOMA PATIENT-DERIVED ORTHOTOPIC XENOGRAFTS: FROM BASIC RESEARCH TO PRECLINICAL STUDIES

Neuro-oncology
2018-11 | Journal article
PMC: PMC6216671
Contributors: Hau A; Golebiewska A; Oudin A; Houben L; Stieber D; Azuaje F; Kaoma T; Muller A; Hertel F; Mittelbronn M et al.
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

P04.64 Molecular characterization of glioma patient derived orthotopic xenografts to improve outcome of preclinical studies

Neuro-oncology
2018-09 | Journal article
PMC: PMC6144237
Contributors: Golebiewska A; Hau A; Oudin A; Houben L; Stieber D; Azuaje F; Kaony T; Muller A; Hertel F; Mittelbronn M et al.
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

Arginine Methylation Regulates MEIS2 Nuclear Localization to Promote Neuronal Differentiation of Adult SVZ Progenitors

Stem Cell Reports
2018-04-10 | Journal article
Part of DOI: 10.1016/j.stemcr.2018.03.010
Source: Self-asserted source
Ann-Christin Hau

Glioma Through the Looking GLASS: the Glioma Longitudinal Analysis consortium, molecular evolution of diffuse gliomas

Neuro-Oncology
2018-02-09 | Journal article
Part of DOI: 10.1093/neuonc/noy020
Source: Self-asserted source
Ann-Christin Hau

Glioma Through the Looking GLASS: the Glioma Longitudinal Analysis consortium, molecular evolution of diffuse gliomas

2017-10 | Preprint
DOI: 10.1101/196139
PPR: PPR15975
Contributors: The GLASS consortium; Aldape K; Amin SB; Ashley DM; Barnholtz-Sloan JS; Bates AJ; Beroukhim R; Bock C; Brat DJ; Claus EB et al.
Source: Self-asserted source
Ann-Christin Hau via Europe PubMed Central

Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways

EMBO Molecular Medicine
2017-10-23 | Journal article
Part of DOI: 10.15252/emmm.201707729
Source: Self-asserted source
Ann-Christin Hau

MEIS homeodomain proteins facilitate PARP1/ARTD1-mediated eviction of histone H1

Journal of Cell Biology
2017-07-24 | Journal article
DOI: 10.1083/jcb.201701154
Source: Self-asserted source
Ann-Christin Hau

PBX1 is required for adult subventricular zone neurogenesis

Development (Cambridge)
2016 | Journal article
DOI: 10.1242/dev.128033
EID:

2-s2.0-84977119719
Contributors: Grebbin, B.M.; Hau, A.-C.; Groß, A.; Anders-Maurer, M.; Schramm, J.; Koss, M.; Wille, C.; Mittelbronn, M.; Selleri, L.; Schulte, D.
Source: Self-asserted source
Ann-Christin Hau via Scopus - Elsevier

Meis2 is a Pax6 co-factor in neurogenesis and dopaminergic periglomerular fate specification in the adult olfactory bulb

Development (Cambridge)
2014 | Journal article
DOI: 10.1242/dev.097295
EID:

2-s2.0-84890489422
Contributors: Agoston, Z.; Heine, P.; Brill, M.S.; Grebbin, B.M.; Hau, A.-C.; Kallenborn-Gerhardt, W.; Schramm, J.; Götz, M.; Schulte, D.
Source: Self-asserted source
Ann-Christin Hau via Scopus - Elsevier
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