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Tampere University: Tampere, FI

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Tampere University: Tampere, FI

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Works (46)

Exploring Kainic Acid-Induced Alterations in Circular Tripartite Networks with Advanced Analysis Tools

eNeuro
2024-07-30 | Journal article | Author
DOI: 10.1523/ENEURO.0035-24.2024
SOURCE-WORK-ID:

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EID:

2-s2.0-85200121587
Contributors: Andrey Vinogradov; emre kapucu; Susanna Narkilahti
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Tampere University
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Human tripartite cortical network model for temporal assessment of alpha-synuclein aggregation and propagation in Parkinson’s Disease

NPJ Parkinson's disease
2024-07-28 | Journal article | Author
DOI: 10.1038/s41531-024-00750-x
SOURCE-WORK-ID:

180009a4-bfef-4620-ab79-c9d53e02c1cf

EID:

2-s2.0-85199982412
Contributors: emre kapucu; Iisa Tujula; Oskari Kulta; Lassi Sukki; Tomi Ryynänen; Hjalte Gram; Valtteri Vuolanto; Andrey Vinogradov; Joose Kreutzer; Poul Henning Jensen et al.
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Tampere University
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MEA Embedded Microphysiological Platform for Studying Parkinson’s Disease Related Α–Synuclein Pathology

MxW Summit 2024, Zurich, Switzerland, 8/04/24
2024-04-08 | Conference abstract | Author
SOURCE-WORK-ID:

37fde907-85ec-4f78-a97d-993ee863a841
Contributors: emre kapucu
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Tampere University

Simultaneous induction of vasculature and neuronal network formation on a chip reveals a dynamic interrelationship between cell types

CELL COMMUNICATION AND SIGNALING
2023 | Journal article | Author
DOI: 10.1186/s12964-023-01159-4
SOURCE-WORK-ID:

b306b8cb-4968-4b1c-a105-081cc528f352

EID:

2-s2.0-85161899554

PMID: 37316873
Contributors: Lotta Isosaari; Hanna Vuorenpää; Alma Yrjänäinen; emre kapucu; Minna Kelloniemi; Toni Karri Pakarinen; Susanna Miettinen; Susanna Narkilahti
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Tampere University

Development of biomimetic glioma-on-chip containing neuronal and vascular networks to study tumor–cell interactions

Vis à vis in the Brain: The Neuron-Glia Interface, Freiburg, Germany, 13/09/23
2023-09 | Conference abstract | Author
SOURCE-WORK-ID:

afea176d-7acc-40ee-844c-8dd861f1dd45
Contributors: Lotta Isosaari; Oskari Kulta; Nanna Förster; Hanna Vuorenpää; Alma Yrjänäinen; emre kapucu; Kirsi Granberg; Susanna Miettinen; Susanna Narkilahti
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Tampere University

In vitro α–synuclein aggregation and propagation model

International Parkinson and Movement Disorder Society Congress 2023, Copenhagen, Denmark, 27/08/23
2023-08 | Conference abstract | Author
SOURCE-WORK-ID:

e9babb4a-f776-444d-96cb-b9e93379d241
Contributors: emre kapucu; Iisa Tujula; Oskari Kulta; Lassi Sukki; Valtteri Vuolanto; Andrey Vinogradov; Pasi Kallio; Susanna Narkilahti
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Tampere University

Human Cortical Neuronal Networks in Microelectrode Embedded Microphysiological System to Study Functional Alterations during Alpha-Synuclein Aggregation and Propagation as Model for Parkinson’s Disease

Microphysiological Systems World Summit, Berlin, Germany, 26/06/23
2023-06 | Conference abstract | Author
SOURCE-WORK-ID:

917c9b6f-1c57-4afa-84c5-f0b87aed65b6
Contributors: emre kapucu; Iisa Tujula; Oskari Kulta; Lassi Sukki; Valtteri Vuolanto; Andrey Vinogradov; Pasi Kallio; Susanna Narkilahti
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Tampere University

Simultaneous Induction of Vasculature and Neuronal Network Formation on a Chip Reveals a Dynamic Interrelationship between Cell Types

Microphysiological Systems World Summit, Berlin, Germany, 26/06/23
2023-06 | Conference abstract | Author
SOURCE-WORK-ID:

664537ab-e9e5-49e4-a6e9-b574c313d9a6
Contributors: Lotta Isosaari; Hanna Vuorenpää; Alma Yrjänäinen; emre kapucu; Minna Kääriäinen; Toni-Karri Pakarinen; Susanna Miettinen; Susanna Narkilahti
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Tampere University

Microfluidic chips with embedded microelectrode arrays for studying “prion-like” propagation of alpha-synuclein aggregates

EUROoCS Conference, France, 4/07/22
2022-07 | Conference abstract | Author
SOURCE-WORK-ID:

3628c59d-4e54-4775-851d-1086b4332a1b
Contributors: emre kapucu; Iisa Tujula; Andrey Vinogradov; Oskari Kulta; Susanna Narkilahti
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Tampere University

Openly available MEA dataset from hPSC-derived and rat cortical networks and associated data analysis pipeline

MEA Meeting 2022, Tübingen, Germany, 6/07/22
2022-07 | Conference abstract | Author
SOURCE-WORK-ID:

b1293686-cc7b-46a6-96fe-863c43453d30
Contributors: Andrey Vinogradov; emre kapucu; Tanja Hyvärinen; Susanna Narkilahti
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Tampere University

Parkinson’s-on-Chip Model: Screening the activity and its propagation of hPSC-derived neurons during α-synuclein aggregation on MEA embedded microfluidic chips

MEA Meeting 2022, Tübingen, Germany, 6/07/22
2022-07 | Conference abstract | Author
SOURCE-WORK-ID:

86207d96-bfee-4d76-9c8d-4d52ef3eb60a
Contributors: emre kapucu; Iisa Tujula; Susanna Narkilahti
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Tampere University

A kainic acid-induced seizure model in human pluripotent stem cell-derived cortical neurons for studying the role of IL-6 in the functional activity

Stem Cell Research
2022-04 | Journal article
DOI: 10.1016/j.scr.2022.102665
Part of ISSN: 1873-5061
Source: Self-asserted source
emre kapucu
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Comparative microelectrode array data of the functional development of hPSC-derived and rat neuronal networks

Scientific Data
2022-03 | Journal article | Author
DOI: 10.1038/s41597-022-01242-4
SOURCE-WORK-ID:

b5409558-e5bf-422c-bc17-b451cdae088c

EID:

2-s2.0-85127275551

PMID: 35354837
Contributors: emre kapucu; Andrey Vinogradov; Tanja Hyvärinen; Laura Ylä-Outinen; Susanna Narkilahti
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Tampere University

An analysis pipeline for signaling of human stem cell derived neurons in a microfluidics platform with an embedded microelectrode array

43rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society EMBC, 31/10/21
2021-11 | Conference abstract | Author
SOURCE-WORK-ID:

1a97fd97-371b-497c-a917-4e2c3fbd4896
Contributors: Andrey Vinogradov; emre kapucu; Susanna Narkilahti
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Tampere University

Analyzing unidirectional axonal growth on microfluidic devices

The European Organ-on-Chip Society Conference 2021, 1/07/21
2021-07 | Conference abstract | Author
SOURCE-WORK-ID:

b5beae85-56b1-4a1b-94ce-f4628f2670f5
Contributors: emre kapucu; Susanna Narkilahti; Lassi Sukki; Pasi Kallio
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Tampere University

Guided axonal growth on a microfluidic device for studying the spread of Parkinson’s disease pathology and its effects on neuronal functionality

ISSCR, 24/06/15
2021-06 | Conference abstract | Author
SOURCE-WORK-ID:

3208c29f-34ea-48d6-8e06-b7026998bf41
Contributors: Iisa Tujula; emre kapucu; Lassi Sukki; Pasi Kallio; Susanna Narkilahti
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Tampere University

Directional Growth of Human Neuronal Axons in a Microfluidic Device with Nanotopography on Azobenzene‐Based Material

Advanced Materials Interfaces
2021-05-03 | Journal article
DOI: 10.1002/admi.202100048
Part of ISSN: 2196-7350
Part of ISSN: 2196-7350
Source: Self-asserted source
emre kapucu
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Corrigendum

Frontiers in Computational Neuroscience
2020-11-04 | Other | Author
DOI: 10.3389/fncom.2020.586506
SOURCE-WORK-ID:

ea0cc6d8-52b2-4363-be51-896cdf8609c9

EID:

2-s2.0-85096171419
Contributors: emre kapucu; Inkeri Välkki; Jarno E. Mikkonen; Chiara Leone; Kerstin Lenk; Jarno M. A. Tanskanen; Jari Aarne Kalevi Hyttinen
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Tampere University

Advances in Human Stem Cell-Derived Neuronal Cell Culturing and Analysis

Advances in Neurobiology
2019 | Book chapter
DOI: 10.1007/978-3-030-11135-9_13
Part of ISBN: 9783030111342
Part of ISBN: 9783030111359
Part of ISSN: 2190-5215
Part of ISSN: 2190-5223
Source: Self-asserted source
emre kapucu
grade
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Functional characterization of human pluripotent stem cell-derived cortical networks differentiated on laminin-521 substrate: comparison to rat cortical cultures

Scientific Reports
2019-12 | Journal article
DOI: 10.1038/s41598-019-53647-8
Part of ISSN: 2045-2322
Source: Self-asserted source
emre kapucu
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On electrophysiological signal complexity during biological neuronal network development and maturation

2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
2017-07 | Conference paper
DOI: 10.1109/embc.2017.8037570
Part of ISBN: 9781509028092
Contributors: Fikret E. Kapucu; Inkeri Valkki; Francois Christophe; Jarno M. A. Tanskanen; Julia Johansson; Tommi Mikkonen; Jari A. K. Hyttinen
Source: Self-asserted source
emre kapucu via Crossref Metadata Search
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Evaluation of the effective and functional connectivity estimators for microelectrode array recordings during in vitro neuronal network maturation

EMBEC & NBC 2017
2017-06 | Other
DOI: 10.1007/978-981-10-5122-7_276
Part of ISBN: 9789811051210
Part of ISSN: 1680-0737
Contributors: Fikret Emre Kapucu; Jarno M. A. Tanskanen; Francois Christophe; Tommi Mikkonen; Jari A. K. Hyttinen
Source: Self-asserted source
emre kapucu via Crossref Metadata Search
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Network-Wide Adaptive Burst Detection Depicts Neuronal Activity with Improved Accuracy

Frontiers in Computational Neuroscience
2017-05 | Journal article
DOI: 10.3389/fncom.2017.00040
Part of ISSN: 1662-5188
Contributors: Inkeri A. Välkki; Kerstin Lenk; Jarno E. Mikkonen; Fikret E. Kapucu; Jari A. K. Hyttinen
Source: Self-asserted source
emre kapucu via Crossref Metadata Search
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Characterizing Neuronal Network Burst Synchrony by Using Burst Signal

Frontiers in Neuroscience
2016 | Journal article
DOI: 10.3389/conf.fnins.2016.93.00079
Part of ISSN: 1662-453X
Contributors: Vornanen Inkeri; Kapucu Fikret; Johansson Julia; Lenk Kerstin; Hyttinen Jari
Source: Self-asserted source
emre kapucu via Crossref Metadata Search
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Objective Thresholding of MEA Data for Action Potential Detection

Frontiers in Neuroscience
2016 | Journal article
DOI: 10.3389/conf.fnins.2016.93.00028
Part of ISSN: 1662-453X
Contributors: A. Tanskanen Jarno; Kapucu Fikret; Vornanen Inkeri; Lenk Kerstin; Hyttinen Jari
Source: Self-asserted source
emre kapucu via Crossref Metadata Search
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The Influence of Structural Changes and Population Interactions on the Entropy Based Synchronicity

Frontiers in Neuroscience
2016 | Journal article
DOI: 10.3389/conf.fnins.2016.93.00053
Part of ISSN: 1662-453X
Contributors: Kapucu Fikret; Vornanen Inkeri; A. Tanskanen Jarno; Christophe Francois; Hyttinen Jari
Source: Self-asserted source
emre kapucu via Crossref Metadata Search
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Methods to Enhance Information Extraction from Microelectrode Array Measurements of Neuronal Networks

Tampere University of Technology. Publication
2016-11-30 | Dissertation or Thesis | Author
SOURCE-WORK-ID:

b6b28f2a-35d8-4869-81f6-011654bc970e

ISBN: 978-952-15-3862-9
ISBN: 978-952-15-3857-5
Contributors: emre kapucu
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Tampere University

Spectral Entropy Based Neuronal Network Synchronization Analysis Based on Microelectrode Array Measurements

Frontiers in Computational Neuroscience
2016-10 | Journal article
DOI: 10.3389/fncom.2016.00112
Part of ISSN: 1662-5188
Contributors: Fikret E. Kapucu; Inkeri Välkki; Jarno E. Mikkonen; Chiara Leone; Kerstin Lenk; Jarno M. A. Tanskanen; Jari A. K. Hyttinen
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emre kapucu via Crossref Metadata Search
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Analyzing the feasibility of time correlated spectral entropy for the assessment of neuronal synchrony

2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
2016-08 | Conference paper
DOI: 10.1109/embc.2016.7591017
Part of ISBN: 9781457702204
Contributors: Fikret E. Kapucu; Jarno E. Mikkonen; Jarno M. A. Tanskanen; Jari A. K. Hyttinen
Source: Self-asserted source
emre kapucu via Crossref Metadata Search
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Automatic objective thresholding to detect neuronal action potentials

2016 24th European Signal Processing Conference (EUSIPCO)
2016-08 | Conference paper
DOI: 10.1109/eusipco.2016.7760331
Part of ISBN: 9780992862657
Contributors: Jarno M. A. Tanskanen; Fikret E. Kapucu; Inkeri Vornanen; Jari A. K. Hyttinen
Source: Self-asserted source
emre kapucu via Crossref Metadata Search
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Automatic Objective Criterion for Setting Neuronal Action Potential Spike Detection Thresholds

10th FENS Forum of Neuroscience, Copenhagen, Denmark, 2/07/16
2016-07-02 | Conference abstract | Author
SOURCE-WORK-ID:

f495a945-2f9f-45f5-9d7a-33019be45d03
Contributors: Jarno M. A. Tanskanen; emre kapucu; Jari Aarne Kalevi Hyttinen
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Tampere University

Joint analysis of extracellular spike waveforms and neuronal network bursts.

Journal of neuroscience methods
2015-12 | Journal article
DOI: 10.1016/j.jneumeth.2015.11.022
PMID: 26675487
Contributors: Kapucu FE; Mäkinen ME; Tanskanen JMA; Ylä-Outinen L; Narkilahti S; Hyttinen JAK
Source: Self-asserted source
emre kapucu via Europe PubMed Central
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A fast stimulability screening protocol for neuronal cultures on microelectrode arrays

2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
2015-08 | Conference paper
DOI: 10.1109/embc.2015.7319132
Part of ISBN: 9781424492718
Contributors: Fikret E. Kapucu; Jarno M. A. Tanskanen; Yuting Yuan; Jari A. K. Hyttinen
Source: Self-asserted source
emre kapucu via Crossref Metadata Search
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Quantification and automatized adaptive detection of in vivo and in vitro neuronal bursts based on signal complexity

2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
2015-08 | Conference paper
DOI: 10.1109/embc.2015.7319450
Part of ISBN: 9781424492718
Contributors: Fikret E. Kapucu; Jarno E. Mikkonen; Jarno M. A. Tanskanen; Jari A. K. Hyttinen
Source: Self-asserted source
emre kapucu via Crossref Metadata Search
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On the threshold based neuronal spike detection, and an objective criterion for setting the threshold

2015 7th International IEEE/EMBS Conference on Neural Engineering (NER)
2015-04 | Conference paper
DOI: 10.1109/ner.2015.7146799
Part of ISBN: 9781467363891
Contributors: Jarno M. A. Tanskanen; Fikret E. Kapucu; Jari A. K. Hyttinen
Source: Self-asserted source
emre kapucu via Crossref Metadata Search
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Burst analysis methods for analyzing maturing neuronal networks with variable firing statistics

Conference Proceedings of the 8th International Meeting on Substrate-Integrated Microelectrode Arrays July 10 - July 13, 2012, Reutlingen, Germany
2012 | Conference paper | Author
SOURCE-WORK-ID:

ac743297-26a9-4d56-b7bb-5e2e4638d0cf
Contributors: emre kapucu; Jarno M. A. Tanskanen; Jarno Mikkonen; Laura Ylä-Outinen; Susanna Narkilahti; Jari Aarne Kalevi Hyttinen
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Tampere University

Burst analysis tool for developing neuronal networks exhibiting highly varying action potential dynamics

Frontiers in Computational Neuroscience
2012 | Journal article
DOI: 10.3389/fncom.2012.00038
Part of ISSN: 1662-5188
Contributors: Fikret E. Kapucu; Jarno M. A. Tanskanen; Jarno E. Mikkonen; Laura Ylä-Outinen; Susanna Narkilahti; Jari A. K. Hyttinen
Source: Self-asserted source
emre kapucu via Crossref Metadata Search
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Tracking the network development of hESC derived neurons during maturation

Proceedings of MEA Meeting 2010, the 7th International Meeting on Substrate-Integrated Microelectrode Arrays, Reutlingen, Germany, June 29 - July 2, 2010
2010 | Conference paper | Author
SOURCE-WORK-ID:

73911ae7-0d3a-495e-acfe-c0ec786a063d

Part of ISBN: 3-938345-08-5
Contributors: emre kapucu; Jarno M. A. Tanskanen; Jarno E. Mikkonen; Laura Ylä-Outinen; Susanna Narkilahti; Jari Aarne Kalevi Hyttinen
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Tampere University

Analysis of spiking activity changes during maturation of hESC derived neurons

Proceedings of the 2009 Symposium on Microelectrode Arrays in Tissue Engineering, 4.-5.6.2009, Tampere, Finland
2009 | Conference paper | Author
SOURCE-WORK-ID:

7fe641ca-0eb6-4cab-ae6d-19d06660d889
Contributors: emre kapucu; L. Ylä-Outinen; T. Heikkilä; J.E. Mikkonen; Jarno M. A. Tanskanen; Susanna Narkilahti; Jari Aarne Kalevi Hyttinen
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Tampere University

Analyzing human embryonic stemcell –derived cardiomyocytes with microelectrode array platform

International society for stem cell research 7th annual meeting, 8-11 July 2009, Barcelona, Spain
2009 | Conference paper | Author
SOURCE-WORK-ID:

033be4d4-5573-4f6d-85a4-b26106a8176b
Contributors: V. Kujala; M. Pekkanen-Mattila; L. Lehtonen; emre kapucu; E. Kerkelä; R. Suuronen; Jari Aarne Kalevi Hyttinen; H. Skottman; K. Aalto-Setälä
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Tampere University

Analyzing human empryonic stem cell-derived cardiomyocytes with microelectrode array platform

Proceedings of the 2009 Symposium on Microelectrode Arrays in Tissue Engineering, 4.-5.6.2009, Tampere, Finland
2009 | Conference paper | Author
SOURCE-WORK-ID:

cba3916b-74eb-4928-b486-432c6fcf3335
Contributors: V. Kujala; M. Pekkanen-Mattila; L. Lehtonen; Z.C. Jimenez; emre kapucu; J. Väisänen; E. Kerkelä; R. Suuronen; Jari Aarne Kalevi Hyttinen; H. Skottman et al.
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Tampere University

Beating Rate Variability Studies with Human Embryonic Stem Cell Derived Cardiomyocytes

4th European Conference of the International Federation for Medical and Biological Engineering
2009 | Other
DOI: 10.1007/978-3-540-89208-3_3
Part of ISBN: 9783540892076
Part of ISSN: 1680-0737
Contributors: F. E. Kapucu; M. Pekkanen-Mattila; V. Kujala; J. Viik; K. Aalto-Setelä; E. Kerkelä; J. M. A. Tanskanen; J. Hyttinen
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emre kapucu via Crossref Metadata Search

Dynamics of activity during the maturation of neural network derived from human embryonic stem cells

The European Future Technologies Conference, Science beyond Fiction, 21.-22. April 2009, Prague, Czech Republic
2009 | Conference paper | Author
SOURCE-WORK-ID:

43e0f328-f9f5-4ca7-b82a-4901411ef4e6
Contributors: Jari Aarne Kalevi Hyttinen; T. Heikkilä; L. Ylä-Outinen; A. Reska; emre kapucu; J. Mikkonen; Jarno M. A. Tanskanen; R. Suuronen; H. Skottman; P. Schulte et al.
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Tampere University

Beating rate variability studies with human embryonic stem cell derived Cardiomyocytes

4th European Conference of the International Federation for Medical and Biological Engineering, 23-27 November 2008, Antwerp, Belgium. IFMBE Proceedings
2008 | Conference paper | Author
SOURCE-WORK-ID:

db719871-529a-4d96-ba7f-664f56b552ad

EID:

2-s2.0-70350625097
Contributors: emre kapucu; M. Pekkanen-Mattila; V. Kujala; Jari Viik; K. Aalto-Setälä; E. Kerkelä; Jarno M. A. Tanskanen; Jari Aarne Kalevi Hyttinen
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Tampere University

Phase coupling in EEG burst suppression during propofol anasthesia

Proceedings of the 14th Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, Riga, Latvia, 16.-20.06.2008
2008 | Conference paper | Author
DOI: 10.1007/978-3-540-69367-3_54
SOURCE-WORK-ID:

c3e838a6-5025-4dfa-80fc-63e1f2bd10a7

Part of ISBN: 978-3-540-69366-6
Contributors: emre kapucu; Tarmo Lipping; V. Jäntti; A.-M. Huotari
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Tampere University

Phase Coupling in EEG Burst Suppression during Propofol Anesthesia

14th Nordic-Baltic Conference on Biomedical Engineering and Medical Physics
2008 | Other
DOI: 10.1007/978-3-540-69367-3_70
Part of ISBN: 9783540693666
Part of ISSN: 1680-0737
Contributors: Fikret Emre Kapucu; T. Lipping; V. Jäntti; A. -M. Huotari
Source: Self-asserted source
emre kapucu via Crossref Metadata Search
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