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Scopus Author ID: 6701554886

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Employment (5)

Penn State Health Milton S Hershey Medical Center: Hershey, PA, US

2021-11-01 to present | Professor and Chair (Pediatrics)
Employment
Source: Self-asserted source
Yatin Vyas

University of Iowa Children's Hospital: Iowa City, IA, US

2013 to present | Division Director (Pediatric Hematology/Oncology)
Employment
Source: Self-asserted source
Yatin Vyas

Children's Hospital of Pittsburgh of UPMC: Pittsburgh, PA, US

2005 to 2011 | Assistant Professor (Pediatrics & Immunology)
Employment
Source: Self-asserted source
Yatin Vyas

Memorial Sloan-Kettering Cancer Center: New York, NY, US

2002 to 2005 | Clinical Assistant Attending (Pediatrics)
Employment
Source: Self-asserted source
Yatin Vyas

Sloan-Kettering Institute: New York, NY, US

2001 to 2002 | Research Associate (Immunology Program)
Employment
Source: Self-asserted source
Yatin Vyas

Education and qualifications (3)

University of Pittsburgh Joseph M Katz Graduate School of Business: Pittsburgh, PA, US

2012 | diploma
Education
Source: Self-asserted source
Yatin Vyas

Gujarat University: Ahmedabad, Gujarat, IN

1990 | MD
Education
Source: Self-asserted source
Yatin Vyas

Gujarat University: Ahmedabad, Gujarat, IN

1987 | MBBS
Education
Source: Self-asserted source
Yatin Vyas

Funding (19)

Epigenetic Regulation by WASP of Human TBX21 Gene Transcription Program

2011-08 to 2015-07 | Grant
National Institute of Allergy and Infectious Diseases (MD, MD, US)
GRANT_NUMBER:

R01 AI084957-04
Source: Self-asserted source
Yatin Vyas

Epigenetic Regulation by WASP of Human TBX21 Gene Transcription Program

2011-08 to 2015-07 | Grant
National Institute of Allergy and Infectious Diseases (MD, MD, US)
GRANT_NUMBER:

R01 AI084957-03
Source: Self-asserted source
Yatin Vyas

Epigenetic Regulation by WASP of Human TBX21 Gene Transcription Program

2011-08 to 2015-07 | Grant
National Institute of Allergy and Infectious Diseases (MD, MD, US)
GRANT_NUMBER:

R01 AI084957-01A1
Source: Self-asserted source
Yatin Vyas

Epigenetic Regulation by WASP of Human TBX21 Gene Transcription Program

2011-08 to 2015-07 | Grant
NIH Office of the Director (MD, MD, US)
GRANT_NUMBER:

R01 A1084957
Source: Self-asserted source
Yatin Vyas

Epigenetic Regulation by WASP of Human TBX21 Gene Transcription Program

2011-08 to 2013-06 | Grant
National Institute of Allergy and Infectious Diseases (MD, MD, US)
GRANT_NUMBER:

R01 AI084957-02
Source: Self-asserted source
Yatin Vyas

The Role of Nuclear WASP in the Transcriptional Regulation of TH1 Differentiation

2008-09 to 2010-08 | Grant
National Institute of Allergy and Infectious Diseases (MD, MD, US)
GRANT_NUMBER:

R21 AI079762-02
Source: Self-asserted source
Yatin Vyas

The Role of Nuclear WASP in the Transcriptional Regulation of TH1 Differentiation

2008-09 to 2009-08 | Grant
National Institute of Allergy and Infectious Diseases (MD, MD, US)
GRANT_NUMBER:

R21 AI079762-01
Source: Self-asserted source
Yatin Vyas

Molecular Pathogenesis of Immune Dysfunction in Wiskott-Aldrich-Syndrome

2008-06 to 2013-05 | Grant
National Institute of Allergy and Infectious Diseases (MD, MD, US)
GRANT_NUMBER:

R01 AI073561-01A2
Source: Self-asserted source
Yatin Vyas

Molecular Pathogenesis of Immune Dysfunction in Wiskott-Aldrich-Syndrome

2008-06 to 2013-05 | Grant
National Institute of Allergy and Infectious Diseases (MD, MD, US)
GRANT_NUMBER:

R01 AI073561-02
Source: Self-asserted source
Yatin Vyas

Molecular Pathogenesis of Immune Dysfunction in Wiskott-Aldrich-Syndrome

2008-06 to 2013-05 | Grant
National Institute of Allergy and Infectious Diseases (MD, MD, US)
GRANT_NUMBER:

R01 AI073561-03
Source: Self-asserted source
Yatin Vyas

Molecular Pathogenesis of Immune Dysfunction in Wiskott-Aldrich-Syndrome

2008-06 to 2013-05 | Grant
National Institute of Allergy and Infectious Diseases (MD, MD, US)
GRANT_NUMBER:

R01 AI073561-04
Source: Self-asserted source
Yatin Vyas

Molecular Pathogenesis of Immune Dysfunction in Wiskott-Aldrich-Syndrome

2008-06 to 2013-05 | Grant
National Institute of Allergy and Infectious Diseases (MD, MD, US)
GRANT_NUMBER:

R01 AI073561-05
Source: Self-asserted source
Yatin Vyas

Immunofluorescent 3D-analysis of NK-target Conjugates

2002-04 to 2008-03 | Grant
National Institute of Allergy and Infectious Diseases (MD, MD, US)
GRANT_NUMBER:

K08 AI051402-06
Source: Self-asserted source
Yatin Vyas

Immunofluorescent 3D-analysis of NK-target Conjugates

2002-04 to 2007-03 | Grant
National Institute of Allergy and Infectious Diseases (MD, MD, US)
GRANT_NUMBER:

K08 AI051402-05
Source: Self-asserted source
Yatin Vyas

Immunofluorescent 3D-analysis of NK-target Conjugates

2002-04 to 2007-03 | Grant
National Institute of Allergy and Infectious Diseases (MD, MD, US)
GRANT_NUMBER:

K08 AI051402-03
Source: Self-asserted source
Yatin Vyas

Immunofluorescent 3D-analysis of NK-target Conjugates

2002-04 to 2007-03 | Grant
National Institute of Allergy and Infectious Diseases (MD, MD, US)
GRANT_NUMBER:

K08 AI051402-02
Source: Self-asserted source
Yatin Vyas

Immunofluorescent 3D-analysis of NK-target Conjugates

2002-04 to 2007-03 | Grant
National Institute of Allergy and Infectious Diseases (MD, MD, US)
GRANT_NUMBER:

K08 AI051402-01
Source: Self-asserted source
Yatin Vyas

Immunofluorescent 3D-analysis of NK-target Conjugates

2002-04 to 2005-06 | Grant
National Institute of Allergy and Infectious Diseases (MD, MD, US)
GRANT_NUMBER:

K08 AI051402-04
Source: Self-asserted source
Yatin Vyas

Support Research Activities

2000-07 to 2016-03 | Grant
National Cancer Institute (MD, MD, US)
GRANT_NUMBER:

5 P30 CA086862-13
Source: Self-asserted source
Yatin Vyas

Works (24)

WASp modulates RPA function on single-stranded DNA in response to replication stress and DNA damage

Nature Communications
2022-06-29 | Journal article
DOI: 10.1038/s41467-022-31415-z
Contributors: Seong-Su Han; Kuo-Kuang Wen; María L. García-Rubio; Marc S. Wold; Andrés Aguilera; Wojciech Niedzwiedz; Yatin M. Vyas
Source: check_circle
Crossref

Deficiency of Wiskott–Aldrich syndrome protein has opposing effect on the pro-oncogenic pathway activation in nonmalignant versus malignant lymphocytes

Oncogene
2021-01-14 | Journal article
DOI: 10.1038/s41388-020-01533-3
Contributors: Seong-Su Han; Kuo-Kuang Wen; Yatin M. Vyas
Source: check_circle
Crossref

Wiskott-Aldrich syndrome protein senses irradiation-induced DNA damage to coordinate the cell-protective Golgi dispersal response in human T and B lymphocytes.

The Journal of allergy and clinical immunology
2019-10-09 | Journal article
DOI: 10.1016/j.jaci.2019.09.026
PMID: 31604087
PMC: PMC6949418
Source: Self-asserted source
Yatin Vyas

R-loops cause genomic instability in T helper lymphocytes from patients with Wiskott-Aldrich syndrome

Journal of Allergy and Clinical Immunology
2018 | Journal article
DOI: 10.1016/j.jaci.2017.11.023
EID:

2-s2.0-85041602808
Contributors: Sarkar, K.; Han, S.-S.; Wen, K.-K.; Ochs, H.D.; Dupré, L.; Seidman, M.M.; Vyas, Y.M.
Source: Self-asserted source
Yatin Vyas via Scopus - Elsevier

SUMOylation-disrupting WAS mutation converts WASp from a transcriptional activator to a repressor of NF-κB response genes in T cells

Blood
2015 | Journal article
DOI: 10.1182/blood-2015-05-646182
EID:

2-s2.0-84947923656
Contributors: Sarkar, K.; Sadhukhan, S.; Han, S.-S.; Vyas, Y.M.
Source: Self-asserted source
Yatin Vyas via Scopus - Elsevier

Congenital dyserythropoietic anemia type I presenting as persistent pulmonary hypertension with pigeon chest deformity

Pediatric Blood and Cancer
2014 | Journal article
DOI: 10.1002/pbc.24945
EID:

2-s2.0-84901992717
Contributors: El-Sheikh, A.A.; Hashem, H.; Holman, C.; Vyas, Y.M.
Source: Self-asserted source
Yatin Vyas via Scopus - Elsevier

Disruption of hSWI/SNF complexes in T cells by WAS mutations distinguishes X-linked thrombocytopenia from Wiskott-Aldrich syndrome

Blood
2014 | Journal article
DOI: 10.1182/blood-2014-07-587642
EID:

2-s2.0-84914104758
Contributors: Sarkar, K.; Sadhukhan, S.; Han, S.-S.; Vyas, Y.M.
Source: Self-asserted source
Yatin Vyas via Scopus - Elsevier
grade
Preferred source (of 2)‎

Mifamurtide in metastatic and recurrent osteosarcoma: A patient access study with pharmacokinetic, pharmacodynamic, and safety assessments

Pediatric Blood and Cancer
2014 | Journal article
DOI: 10.1002/pbc.24686
EID:

2-s2.0-84890878456
Contributors: Anderson, P.M.; Meyers, P.; Kleinerman, E.; Venkatakrishnan, K.; Hughes, D.P.; Herzog, C.; Huh, W.; Sutphin, R.; Vyas, Y.M.; Shen, V. et al.
Source: Self-asserted source
Yatin Vyas via Scopus - Elsevier

Nuclear role of WASp in gene transcription is uncoupled from its ARP2/3-dependent cytoplasmic role in actin polymerization

Journal of Immunology
2014 | Journal article
DOI: 10.4049/jimmunol.1302923
EID:

2-s2.0-84903556116
Contributors: Sadhukhan, S.; Sarkar, K.; Taylor, M.; Candotti, F.; Vyas, Y.M.
Source: Self-asserted source
Yatin Vyas via Scopus - Elsevier

Nuclear role of WASp in the pathogenesis of dysregulated T<inf>H</inf>1 immunity in human Wiskott-Aldrich syndrome

Science Translational Medicine
2010 | Journal article
DOI: 10.1126/scitranslmed.3000813
EID:

2-s2.0-77955600265
Contributors: Taylor, M.D.; Sadhukhan, S.; Kottangada, P.; Ramgopal, A.; Sarkar, K.; D'Silva, S.; Selvakumar, A.; Candotti, F.; Vyas, Y.M.
Source: Self-asserted source
Yatin Vyas via Scopus - Elsevier

Vitamin D<inf>3</inf>attenuates Th2 responses to Aspergillus fumigatus mounted by CD4<sup>+</sup>T cells from cystic fibrosis patients with allergic bronchopulmonary aspergillosis

Journal of Clinical Investigation
2010 | Journal article
DOI: 10.1172/JCI42388
EID:

2-s2.0-77956407606
Contributors: Kreindler, J.L.; Steele, C.; Nguyen, N.; Chan, Y.R.; Pilewski, J.M.; Alcorn, J.F.; Vyas, Y.M.; Aujla, S.J.; Finelli, P.; Blanchard, M. et al.
Source: Self-asserted source
Yatin Vyas via Scopus - Elsevier

Head and neck epithelioid sarcoma in a child: Diagnostic dilemma and anterolateral thigh free flap reconstruction

International Journal of Pediatric Otorhinolaryngology
2008 | Journal article
DOI: 10.1016/j.ijporl.2008.01.032
EID:

2-s2.0-41149125328
Contributors: Nayak, J.V.; Teot, L.A.; Vyas, Y.; Snyderman, C.H.; Toh, E.H.; Deleyiannis, F.W.-B.
Source: Self-asserted source
Yatin Vyas via Scopus - Elsevier

Protein kinase cα and ζ differentially regulate death-inducing signaling complex formation in cigarette smoke extract-induced apoptosis

Journal of Immunology
2008 | Journal article
EID:

2-s2.0-44449178882
Contributors: Park, J.-W.; Kim, H.P.; Lee, S.-J.; Wang, X.; Wang, Y.; Ifedigbo, E.; Watkins, S.C.; Ohba, M.; Ryter, S.W.; Vyas, Y.M. et al.
Source: Self-asserted source
Yatin Vyas via Scopus - Elsevier

Antiparallel segregation of Notch components in the immunological synapse directs reciprocal signaling in allogeneic Th:DC conjugates

Journal of Immunology
2007 | Journal article
DOI: 10.4049/jimmunol.179.2.819
EID:

2-s2.0-34548721648
Contributors: Luty, W.H.; Rodeberg, D.; Parness, J.; Vyas, Y.M.
Source: Self-asserted source
Yatin Vyas via Scopus - Elsevier

Simvastatin promotes Th2-type responses through the induction of the chitinase family member Ym1 in dendritic cells

Proceedings of the National Academy of Sciences of the United States of America
2006 | Journal article
DOI: 10.1073/pnas.0508492103
EID:

2-s2.0-33646753396
Contributors: Arora, M.; Chen, L.; Paglia, M.; Gallagher, J.; Allen, J.E.; Vyas, Y.M.; Ray, A.; Ray, P.
Source: Self-asserted source
Yatin Vyas via Scopus - Elsevier

Erratum: The Wiskott-Aldrich syndrome protein regulates nuclear translocation of NFAT2 and NF-κB (RelA) independently of its role in filamentous actin polymerization and actin cytoskeletal rearrangement (The Journal of Immunology (2005) 174 (2602-2611))

Journal of Immunology
2005 | Journal article
EID:

2-s2.0-17044371574
Contributors: Huang, W.; Ochs, H.D.; Dupont, B.; Vyas, Y.M.
Source: Self-asserted source
Yatin Vyas via Scopus - Elsevier

Treatment of osteosarcoma at first recurrence after contemporary therapy: The memorial sloan-kettering cancer center experience

Cancer
2005 | Journal article
DOI: 10.1002/cncr.21417
EID:

2-s2.0-27644497180
Contributors: Chou, A.J.; Merola, P.B.; Wexler, L.H.; Gorlick, R.G.; Vyas, Y.M.; Healey, J.H.; Laquaglia, M.P.; Huvos, A.G.; Meyers, P.A.
Source: Self-asserted source
Yatin Vyas via Scopus - Elsevier

Ligand binding to inhibitory killer cell Ig-like receptors induce colocalization with Src homology domain 2-containing protein tyrosine phosphatase 1 and interruption of ongoing activation signals

Journal of Immunology
2004 | Journal article
DOI: 10.4049/jimmunol.173.3.1571
EID:

2-s2.0-3242812644
Contributors: Vyas, Y.M.; Maniar, H.; Lyddane, C.E.; Sadelain, M.; Dupont, B.
Source: Self-asserted source
Yatin Vyas via Scopus - Elsevier

Evasion from NK Cell Immunity by MHC Class I Chain-Related Molecules Expressing Colon Adenocarcinoma

Journal of Immunology
2003 | Journal article
DOI: 10.4049/jimmunol.171.12.6891
EID:

2-s2.0-0347627712
Contributors: Doubrovina, E.S.; Doubrovin, M.M.; Vider, E.; Sisson, R.B.; O'Reilly, R.J.; Dupont, B.; Vyas, Y.M.
Source: Self-asserted source
Yatin Vyas via Scopus - Elsevier

Cutting edge: Differential segregation of the Src homology 2-containing protein tyrosine phosphatase-1 within the early NK cell immune synapse distinguishes noncytolytic from cytolytic interactions

Journal of Immunology
2002 | Journal article
DOI: 10.4049/jimmunol.168.7.3150
EID:

2-s2.0-0036533576
Contributors: Vyas, Y.M.; Maniar, H.; Dupont, B.
Source: Self-asserted source
Yatin Vyas via Scopus - Elsevier

Visualization of signaling pathways and cortical cytoskeleton in cytolytic and noncytolytic natural killer cell immune synapses

Immunological Reviews
2002 | Journal article
DOI: 10.1034/j.1600-065X.2002.18914.x
EID:

2-s2.0-0036864628
Contributors: Vyas, Y.M.; Maniar, H.; Dupont, B.
Source: Self-asserted source
Yatin Vyas via Scopus - Elsevier

Spatial organization of signal transduction molecules in the NK cell immune synapses during MHC class I-regulated noncytolytic and cytolytic interactions

Journal of Immunology
2001 | Journal article
DOI: 10.4049/jimmunol.167.8.4358
EID:

2-s2.0-0035887645
Contributors: Vyas, Y.M.; Mehta, K.M.; Morgan, M.; Maniar, H.; Butros, L.; Jung, S.; Burkhardt, J.K.; Dupont, B.
Source: Self-asserted source
Yatin Vyas via Scopus - Elsevier

Multiple transcripts of the killer cell immunoglobulin-like receptor family, KIR3DL1 (NKB1), are expressed by natural killer cells of a single individual

Tissue Antigens
1998 | Journal article
DOI: 10.1111/j.1399-0039.1998.tb03081.x
EID:

2-s2.0-0032442798
Contributors: Vyas, Y.M.; Selvakumar, A.; Steffens, U.; Dupont, B.
Source: Self-asserted source
Yatin Vyas via Scopus - Elsevier

Nucleotide and amino acid sequence alignment for human killer cell inhibitory receptors (KIR), 1998

Tissue Antigens
1998 | Journal article
EID:

2-s2.0-0031958244
Contributors: Steffens, U.; Vyas, Y.; Dupont, B.; Selvakumar, A.
Source: Self-asserted source
Yatin Vyas via Scopus - Elsevier

Peer review (1 review for 1 publication/grant)

Review activity for Journal of clinical immunology. (1)
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