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Employment (1)

Port Said University: Port Said, EG

professor (Pharmaceutical organic chemistry)
Employment
Source: Self-asserted source
samar elkalyoubi

Education and qualifications (1)

Zagazig University: Zagazig, Sharkia, EG

1985-09 to 1990-05 | Bachler degree
Education
Source: Self-asserted source
samar elkalyoubi

Works (32)

Synthesis, In-Vitro, In-Vivo screening, and molecular docking of disubstituted aminothiazole derivatives and their selenium nanoparticles as potential antiparkinson agents

Journal of Molecular Structure
2024-11 | Journal article
DOI: 10.1016/j.molstruc.2024.138951
Part of ISSN: 0022-2860
Contributors: lamiaa osama; Abo El-Magd; SAMAR ALMEHMADI; Ahmed A. El-Sayed; Reham R. Khattab; Samar El-Kalyoubi; sherin Elfeky
Source: Self-asserted source
samar elkalyoubi

Novel pyrimidine Schiff bases and their selenium-containing nanoparticles as dual inhibitors of CDK1 and tubulin polymerase: design, synthesis, anti-proliferative evaluation, and molecular modelling

Journal of Enzyme Inhibition and Medicinal Chemistry
2023-12-31 | Journal article
DOI: 10.1080/14756366.2023.2232125
Contributors: Samar El-Kalyoubi; Samiha A. El-Sebaey; Ahmed A. El-Sayed; Moustafa S. Abdelhamid; Fatimah Agili; Sherin M. Elfeky
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Crossref

Synthesis, DFT calculations, and anti-proliferative evaluation of pyrimidine and selenadiazolopyrimidine derivatives as dual Topoisomerase II and HSP90 inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry
2023-12-31 | Journal article
DOI: 10.1080/14756366.2023.2198163
Contributors: Samar El-Kalyoubi; Samiha A. El-Sebaey; A. M. Rashad; Hanan A. AL-Ghulikah; Mostafa M. Ghorab; Sherin M. Elfeky
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Crossref

Novel Aminopyrimidine-2,4-diones, 2-Thiopyrimidine-4-ones, and 6-Arylpteridines as Dual-Target Inhibitors of BRD4/PLK1: Design, Synthesis, Cytotoxicity, and Computational Studies

Pharmaceuticals
2023-09-15 | Journal article
DOI: 10.3390/ph16091303
Contributors: Samar El-Kalyoubi; Samiha A. El-Sebaey; Sherin M. Elfeky; Hanan A. AL-Ghulikah; Mona S. El-Zoghbi
Source: check_circle
Crossref
grade
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Design, Synthesis, and Biological Evaluation of New Potential Unusual Modified Anticancer Immunomodulators for Possible Non-Teratogenic Quinazoline-Based Thalidomide Analogs

International Journal of Molecular Sciences
2023-08-04 | Journal article
DOI: 10.3390/ijms241512416
Contributors: Reda Mabrouk; Abdallah Abdallah; Hazem Mahdy; Samar El-Kalyoubi; Omar Kamal; Tamer Abdelghany; Mohamed Zayed; Heba Alshaeri; Moudi Alasmari; Mohamed El-Zahabi
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Crossref
grade
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Discovery of New Uracil and Thiouracil Derivatives as Potential HDAC Inhibitors

Pharmaceuticals
2023-07-06 | Journal article
DOI: 10.3390/ph16070966
Contributors: Omnia R. Elbatrawy; Mohamed Hagras; Moshira A. El Deeb; Fatimah Agili; Maghawry Hegazy; Ahmed A. El-Husseiny; Mahmoud Mohamed Mokhtar; Samy Y. Elkhawaga; Ibrahim H. Eissa; Samar El-Kalyoubi
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Crossref
grade
Preferred source (of 2)‎

Design and Synthesis of Novel Uracil-Linked Schiff Bases As Dual Histone Deacetylase Type II/topoisomerase Type I Inhibitors With Apoptotic Potential

Future Medicinal Chemistry
2023-06 | Journal article
DOI: 10.4155/fmc-2023-0112
Contributors: Samar El-Kalyoubi; Samar S Elbaramawi; Ahmed G Eissa; Essam Al-Ageeli; Yahya Hasan Hobani; Aya Ali El-Sharkawy; Hossam Taha Mohamed; Ahmed A Al-Karmalawy; Hamada S Abulkhair
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Crossref

New Thiouracil Derivatives As Histone Deacetylase Inhibitors and Apoptosis Inducers: Design, Synthesis and Anticancer Evaluation

Future Medicinal Chemistry
2023-06 | Journal article
DOI: 10.4155/fmc-2023-0106
Contributors: Omnia R Elbatrawy; Moshira A El Deeb; Mohamed Hagras; Fatimah Agili; Maghawry Hegazy; Ahmed A El-Husseiny; Mohamed A Elkady; Ibrahim H Eissa; Samar El-Kalyoubi
Source: check_circle
Crossref

Design, Synthesis, and Anti-Proliferative Action of Purine/Pteridine-Based Derivatives as Dual Inhibitors of EGFR and BRAFV600E

Pharmaceuticals
2023-05-08 | Journal article
DOI: 10.3390/ph16050716
Contributors: Samar A. El-Kalyoubi; Hesham A. M. Gomaa; Elshimaa M. N. Abdelhafez; Mohamed Ramadan; Fatimah Agili; Bahaa G. M. Youssif
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Crossref
grade
Preferred source (of 2)‎

Synthesis and In Vitro Study of pyrimidine–phthalimide Hybrids As VEGFR2 Inhibitors With Antiproliferative Activity

Future Medicinal Chemistry
2023-04 | Journal article
DOI: 10.4155/fmc-2023-0025
Contributors: Wael Shehta; Fatimah Agili; Basant Farag; Shaker Youssif; Samar J Almehmadi; Sherin M Elfeky; Samar El-Kalyoubi
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Crossref

Design, Synthesis and Antitumor Activity of Novel pyran-functionalized Uracil Derivatives: Docking Studies

Future Medicinal Chemistry
2023-03 | Journal article
DOI: 10.4155/fmc-2022-0279
Contributors: Wael Shehta; Fatimah Agili; Basant Farag; Said A Said; Shaker Youssif; Mohamed E Abdraboh; Samar El-Kalyoubi
Source: check_circle
Crossref

Novel uracil derivatives depicted potential anticancer agents: In Vitro, molecular docking, and ADME study

Arabian Journal of Chemistry
2022-04 | Journal article
DOI: 10.1016/j.arabjc.2021.103669
Part of ISSN: 1878-5352
Source: Self-asserted source
samar elkalyoubi

Uracil as a Zn-Binding Bioisostere of the Allergic Benzenesulfonamide in the Design of Quinoline–Uracil Hybrids as Anticancer Carbonic Anhydrase Inhibitors

Pharmaceuticals
2022-04-19 | Journal article
DOI: 10.3390/ph15050494
Part of ISSN: 1424-8247
Source: Self-asserted source
samar elkalyoubi

One-Pot Synthesis and Molecular Modeling Studies of New Bioactive Spiro-Oxindoles Based on Uracil Derivatives as SARS-CoV-2 Inhibitors Targeting RNA Polymerase and Spike Glycoprotein

Pharmaceuticals
2022-03-20 | Journal article
DOI: 10.3390/ph15030376
Part of ISSN: 1424-8247
Source: Self-asserted source
samar elkalyoubi

Synthesis, Molecular Docking and Anticancer Activity of Some 5‐Aryl‐5,10‐dihydropyrido[2,3‐ d :6,5‐ d′ ]dipyrimidine‐2,4,6,8‐tetraone Derivatives and Pyrido[2,3‐ d ]pyrimidines

ChemistrySelect
2022-02-18 | Journal article
DOI: 10.1002/slct.202103834
Part of ISSN: 2365-6549
Part of ISSN: 2365-6549
Source: Self-asserted source
samar elkalyoubi
grade
Preferred source (of 2)‎

REVIEW ON THE SIGNIFICANCE OF QUINAZOLINE DERIVATIVES AS BROAD SPECTRUM ANTI-CANCER AGENTS.

Az. J. Pharm Sci.
2021 | Journal article
Source: Self-asserted source
samar elkalyoubi

Synthesis and Anticancer Activity Evaluation of Some Thienopyrimidine Derivatives

Russian Journal of Bioorganic Chemistry
2021-11 | Journal article
DOI: 10.1134/s1068162021060194
Part of ISSN: 1068-1620
Part of ISSN: 1608-330X
Source: Self-asserted source
samar elkalyoubi

Synthesis, In Silico Prediction and In Vitro Evaluation of Antimicrobial Activity, DFT Calculation and Theoretical Investigation of Novel Xanthines and Uracil Containing Imidazolone Derivatives

International Journal of Molecular Sciences
2021-10-12 | Journal article
DOI: 10.3390/ijms222010979
Part of ISSN: 1422-0067
Source: Self-asserted source
samar elkalyoubi
grade
Preferred source (of 3)‎

In vitro antimicrobial evaluation and in silico studies of coumarin derivatives tagged with pyrano-pyridine and pyrano-pyrimidine moieties as DNA gyrase inhibitors

Molecular Diversity
2021-04-25 | Journal article
DOI: 10.1007/s11030-021-10224-4
Part of ISSN: 1381-1991
Part of ISSN: 1573-501X
Source: Self-asserted source
samar elkalyoubi

Synthesis, In Silico Prediction and In Vitro Evaluation of Antitumor Activities of Novel Pyrido[2,3-<i>d</i>]pyrimidine, Xanthine and Lumazine Derivatives

Molecules
2020-11 | Journal article | Author
DOI: 10.3390/molecules25215205
Contributors: samar elkalyoubi; Fatimah Agili
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Synthesis, characterization and antimicrobial activities of some 5-bromouracilmetal ion complexes

Bulletin of the Chemical Society of Ethiopia
2019-07-15 | Journal article
DOI: 10.4314/bcse.v33i2.6
Part of ISSN: 1726-801X
Part of ISSN: 1011-3924
Source: Self-asserted source
samar elkalyoubi

Correction: El-kalyoubi, S.; et al. Novel 2-Thioxanthine and Dipyrimidopyridine Derivatives: Synthesis and Antimicrobial Activity. <em>Molecules</em>, 2015, <em>20</em>, 19263–19276

Molecules
2018-06 | Journal article
DOI: 10.3390/molecules23071592
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Synthesis and anticancer evaluation of some novel pyrimido[5,4-e][1,2,4]triazines and pyrazolo[3,4-d]pyrimidine using DMF-DMA as methylating and cyclizing agent.

Chemistry Central journal
2018-05-23 | Journal article
DOI: 10.1186/s13065-018-0424-3
PMID: 29796716
PMC: PMC5966350
Source: Self-asserted source
samar elkalyoubi

One pot synthesis, antimicrobial and antioxidant activities of fused uracils: pyrimidodiazepines, lumazines, triazolouracil and xanthines

Chemistry Central Journal
2017-12 | Journal article
DOI: 10.1186/s13065-017-0294-0
Part of ISSN: 1752-153X
Source: Self-asserted source
samar elkalyoubi

Synthesis and Evaluation of Antitumour Activities of Novel Fused Tri- and Tetracyclic Uracil Derivatives

Journal of Chemical Research
2016-12 | Journal article
DOI: 10.3184/174751916x14798125870610
Part of ISSN: 1747-5198
Part of ISSN: 2047-6507
Source: Self-asserted source
samar elkalyoubi

A Novel Synthesis of Fused Uracils: Indenopyrimidopyridazines, Pyrimidopyridazines, and Pyrazolopyrimidines for Antimicrobial and Antitumor Evalution

Molecules
2016-12-14 | Journal article
DOI: 10.3390/molecules21121714
Part of ISSN: 1420-3049
Source: Self-asserted source
samar elkalyoubi
grade
Preferred source (of 2)‎

Novel 2-Thioxanthine and Dipyrimidopyridine Derivatives: Synthesis and Antimicrobial Activity.

Molecules (Basel, Switzerland)
2015-10-22 | Journal article
DOI: 10.3390/molecules201019263
PMID: 26506337
PMC: PMC6332104
Source: Self-asserted source
samar elkalyoubi
grade
Preferred source (of 2)‎

A Novel one-pot and efficient procedure for synthesis of new fused uracil derivatives for DNA binding

International Journal of Organic Chemistry
2015-03 | Journal article
Contributors: samar elkalyoubi
Source: Self-asserted source
samar elkalyoubi

One pot Synthesis, DNA binding and fragmentation in vitro of new fused uracil derivatives for anticancer properties

Afindad
2012 | Journal article
Contributors: samar elkalyoubi
Source: Self-asserted source
samar elkalyoubi

Synthesis, DNA binding studies of new pyrimidothiazepine and pyrimidobenzothiazepine derivatives

Afindad
2012 | Journal article
Contributors: samar elkalyoubi
Source: Self-asserted source
samar elkalyoubi

Synthesis, DNA Binding and Antiviral Activity of New Uracil, Xanthine, and Pteridine Derivatives

Arch Pharm. Chem. Life Sci
2007 | Journal article
Contributors: samar elkalyoubi
Source: Self-asserted source
samar elkalyoubi

The Yoneda – Reaction

Pteridines
1997 | Conference paper
Contributors: samar elkalyoubi
Source: Self-asserted source
samar elkalyoubi
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