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University of South Australia: Adelaide, South Australia, AU

Professor of Leukaemia Biology (Centre for Cancer Biology)
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Richard D'Andrea

The University of South Australia: Adelaide, AU

Employment
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The University of South Australia

Works (50 of 72)

Items per page:
Page 1 of 2

IDH-mutant myeloid neoplasms are associated with seronegative rheumatoid arthritis and innate immune activation

Blood
2024 | Journal article | Author
Part of ISSN: 0006-4971
EID:

2-s2.0-85188022438

WOSUID:

001239978300001

Contributors: Saumya Samaraweera; Susan Branford; Kok, Chung Hoow; Hong, Lih En; Christopher N Hahn; Small, Annabelle; Nirmal Robinson; Kutyna, Monika; Brown, Anna; Hamish S Scott et al.
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The University of South Australia

Loss of the stress sensor GADD45A promotes stem cell activity and ferroptosis resistance in LGR4/HOXA9-dependent AML

Blood
2024 | Journal article | Author
Part of ISSN: 0006-4971
EID:

2-s2.0-85193621794

WOSUID:

001268835800001

Contributors: Richard D'Andrea; Saumya Samaraweera; Debora Casolari; Hassan, Nunki; Malik, Bilal; Yi, Hangyu; Wang, Jenny Y; Gaspard-Boulinc, Lucie
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The University of South Australia

Circular RNAs drive oncogenic chromosomal translocations within the MLL recombinome in leukemia

Cancer Cell
2023 | Journal article | Author
Part of ISSN: 1535-6108
EID:

2-s2.0-85163863584

WOSUID:

001039408300001

Contributors: John Toubia; Saumya Samaraweera; Gregory Goodall; Sheree Bailey; Liu, Dawei; Pitson, Stuart M; Kirk, Kirsty; GOKHAN CILDIR; Gabryelska, Marta; Richard D'Andrea et al.
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The University of South Australia

Distinct assemblies of heterodimeric cytokine receptors govern stemness programs in leukemia

Cancer Discovery
2023 | Journal article | Author
Part of ISSN: 2159-8274
EID:

2-s2.0-85166480449

WOSUID:

001047140200001

Contributors: Richard D'Andrea; Gomez, Guillermo A; Dhagat, Urmi; Thomas, Daniel; Kaufmann, Kerstin B; Tvorogov, Denis; Saumya Samaraweera; Lopez, Angel F; Dottore, Mara; John Toubia et al.
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The University of South Australia

Kinetic effects of transferrin-conjugated gold nanoparticles on the antioxidant glutathione-thioredoxin pathway

Antioxidants
2023 | Journal article | Author
Part of ISSN: 2076-3921
EID:

2-s2.0-85169106420

WOSUID:

001056839800001

Contributors: Turnbull, Tyron; Alexiou, Christoph; Unterweger, Harald; Richard D'Andrea; Young, Clifford; Manuela Klingler-Hoffmann; Howard, Douglas; Washington, Jenni; Peter Hoffmann; Ivan Kempson et al.
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The University of South Australia

Novel modes of MPL activation in triple-negative myeloproliferative neoplasms

Pathology
2023 | Journal article | Author
Part of ISSN: 0031-3025
EID:

2-s2.0-85136683843

WOSUID:

000938667100001

Contributors: Moore, Sarah; Saumya Samaraweera; Richard D'Andrea; Tran Nguyen; Butcher, Carolyn; Feng, Jinghua; Schreiber, Andreas W; Christopher N Hahn; Debora Casolari; Grove, Carolyn S et al.
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The University of South Australia

Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia

Blood
2022 | Journal article | Author
Part of ISSN: 0006-4971
EID:

2-s2.0-85133172978

WOSUID:

000838708600011

Contributors: Nwosu, Gus O; Ali, Saira R; Ross, David M; Nirmal Robinson; Andrew Bert; Wallington-Beddoe, Craig T; Pitson, Stuart M; Jason Powell; Richard D'Andrea; Lewis, Alexander C et al.
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The University of South Australia

Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia

Nature Communications
2022 | Journal article | Author
Part of ISSN: 2041-1723
EID:

2-s2.0-85130636676

WOSUID:

000795171100036

Contributors: Saumya Samaraweera; Lim, Kelly; Debora Casolari; Bassal, Mahmoud A; Thomas Gonda; Nguyen, Tran; Brown, Anna L; Bernard, Brooks A; Maung, Kyaw Ze Ya; John Toubia et al.
Source: check_circle
The University of South Australia

C/EBPss is a MYB- and p300-cooperating pro-leukemogenic factor and promising drug target in acute myeloid leukemia

Oncogene
2021 | Journal article | Author
Part of ISSN: 0950-9232
EID:

2-s2.0-85105120554

WOSUID:

000648041500001

Contributors: Horn, Melanie; Lenz, Mairin; Mikesch, Jan Henrik; Klempnauer, Karl Heinz; Schmidt, Thomas J; Dörner, Wolfgang; Abdel Ghani, Luca; Casolari, Debora A; Müller-Tidow, Carsten; Arteaga, Maria Francisca et al.
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The University of South Australia

Childhood acute myeloid leukemia shows a high level of germline predisposition

Blood
2021 | Journal article | Author
Part of ISSN: 0006-4971
EID:

2-s2.0-85120354089

WOSUID:

000730824000017

Contributors: Wang, Paul PS; Saumya Samaraweera; Brown, Anna L; Feng, Jinghua; Thomas Gonda; Schreiber, Andreas W; Richard D'Andrea; Li, Ka Leung; Christopher N Hahn; Debora Casolari et al.
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The University of South Australia

Genomic and evolutionary portraits of disease relapse in acute myeloid leukemia

Leukemia
2021 | Journal article | Author
Part of ISSN: 0887-6924
EID:

2-s2.0-85101004531

WOSUID:

000617491500002

Contributors: Rapaport, Franck; Richard D'Andrea; Hassane, Duane; Garrett-Bakelman, Francine E; Neelamraju, Yaseswini; Baslan, Timour
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The University of South Australia

Targeted gene panels identify a high frequency of pathogenic germline variants in patients diagnosed with a hematological malignancy and at least one other independent cancer

Leukemia
2021 | Journal article | Author
Part of ISSN: 0887-6924
EID:

2-s2.0-85104528659

WOSUID:

000639695000001

Contributors: Brown, Anna L; Christopher N Hahn; Schreiber, Andreas W; Richard D'Andrea; Wee, Li Yan A; Eshraghi, Leila; Feng, Jinghua; Hamish S Scott; Feurstein, Simone; Hiwase, Devendra K et al.
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The University of South Australia

Distinct effects of ruxolitinib and interferon-alpha on murine JAK2V617F myeloproliferative neoplasm hematopoietic stem cell populations

Leukemia
2020 | Journal article | Author
Part of ISSN: 0887-6924
EID:

2-s2.0-85075230941

WOSUID:

000522798800010

Contributors: Lane, Steven W; Austin, Rebecca J; Straube, Jasmin; Pali, Gabor; Richard D'Andrea; Bruedigam, Claudia
Source: check_circle
The University of South Australia

RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML

Blood Advances
2020 | Journal article | Author
Part of ISSN: 2473-9529
EID:

2-s2.0-85082318605

WOSUID:

000521788300019

Contributors: Arts, Peer; Claire Homan; Richard D'Andrea; Christopher N Hahn; Feng, Jinghua; Ha, Thuong; King-Smith, Sarah L; Brown, Anna L; Peter Brautigan; Butcher, Carolyn et al.
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The University of South Australia

Targeting RSPO3-LGR4 signaling for leukemia stem cell eradication in acute myeloid leukemia

Cancer cell
2020 | Journal article | Author
Part of ISSN: 1535-6108
EID:

2-s2.0-85088944709

WOSUID:

000559591600013

Contributors: Yi, Hangyu; Salik, Basit; Richard D'Andrea; Wang, Jenny Y; Santiappillai, Nancy; Hassan, Nunki
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The University of South Australia

Genomic subtyping and therapeutic targeting of acute erythroleukemia

Nature genetics
2019 | Journal article | Author
Part of ISSN: 1061-4036
EID:

2-s2.0-85063892573

WOSUID:

000462767500016

Contributors: Lewis, Ian D; Hamish S Scott; Wen, Ji; Christopher N Hahn; Mullighan, Charles G; Brown, Anna L; Richard D'Andrea; Iacobucci, Ilaria; Choi, John K; Meggendorfer, Manja
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The University of South Australia

Hypoxia Induced ER Stress Response as an Adaptive Mechanism in Cancer

International journal of molecular sciences
2019 | Journal article | Author
Part of ISSN: 1422-0067
EID:

2-s2.0-85061484067

WOSUID:

000462412500293

Contributors: Kannan, Elango; Nirmal Robinson; Richard D'Andrea; Tergaonkar, Vinay; Chipurupalli, Sandhya
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The University of South Australia

The mutational burden of therapy-related myeloid neoplasms is similar to primary myelodysplastic syndrome but has a distinctive distribution

Leukemia
2019 | Journal article | Author
Part of ISSN: 0887-6924
EID:

2-s2.0-85065913094

WOSUID:

000499633100007

Contributors: Wee, Li Yan A; Kutyna, Monika M; Schreiber, Andreas W; Richard D'Andrea; Feng, Jinghua; Chhetri, Rakchha; Hiwase, DK; Susan Branford; Singhal, Deepak
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The University of South Australia

A four-gene LincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patients

Leukemia
2018 | Journal article | Author
Part of ISSN: 0887-6924
EID:

2-s2.0-85042281434

WOSUID:

000424517300003

Contributors: Richard D'Andrea; Brown, A; Lewis, ID; Beck, D; Palu, C; Perugini, M; Pimanda, JE; Hamish S Scott; Herold, T; Christopher N Hahn et al.
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The University of South Australia

Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes

Leukemia
2018 | Journal article | Author
Part of ISSN: 0887-6924
EID:

2-s2.0-85028566824

WOSUID:

000419771800021

Contributors: Richard D'Andrea; Babic, M; Chong, C-E; Matthews, JM; Lee, YK; Peter Brautigan; Engler, GA; Brown, AL; Stokes, PH; Venugopal, P et al.
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The University of South Australia

Rare variants in Fanconi anemia genes are enriched in acute myeloid leukemia

Blood cancer journal
2018 | Journal article | Author
Part of ISSN: 2044-5385
EID:

2-s2.0-85048727789

WOSUID:

000477924800001

Contributors: Saumya Samaraweera; GOKHAN CILDIR; Leo, Paul J; Singhal, Deepak; Tran Nguyen; Bassal, Mahmoud; Richard D'Andrea; Bray, Sarah C; Debora Casolari; Brown, Anna L et al.
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The University of South Australia

A novel, somatic, transforming mutation in the extracellular domain of epidermal growth factor receptor identified in myeloproliferative neoplasm

Scientific reports
2017 | Journal article | Author
Part of ISSN: 2045-2322
EID:

2-s2.0-85019730186

WOSUID:

000402045400009

Contributors: Bray, SC; Lewis, ID; Christopher N Hahn; Susan Branford; Maung, KZY; Kok, CH; Parker, WT; Tran Nguyen; Ross, DM; Wee, A et al.
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The University of South Australia

Apparent 'JAK2-negative' polycythaemia vera due to compound mutations in exon 14

British journal of haematology
2017 | Journal article | Author
Part of ISSN: 0007-1048
EID:

2-s2.0-84964762437

WOSUID:

000405272600021

Contributors: Ross, David M; Hahn, Christopher N; Debora Casolari; Zantomio, Daniela; Tran Nguyen; Hamish S Scott; Richard D'Andrea; Tiong, Ing Soo; Moore, Sarah; Van Velzen, Merel JM
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The University of South Australia

High CD123 levels enhance proliferation in response to IL-3, but reduce chemotaxis by downregulating CXCR4 expression

Blood advances
2017 | Journal article | Author
Part of ISSN: 2473-9529
EID:

2-s2.0-85041112828

WOSUID:

000404535700008

Contributors: Nicole L. Wittwer; Lopez, Angel F; Pudney, Melanie K; Brumatti, Gabriela; Ekert, Paul G; Ramshaw, Hayley S; Richard D'Andrea; Sandow, Jarrod J; Dottore, Mara; Ceilidh Marchant
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The University of South Australia

miR-155 as a potential target of IL-3 signaling in primary AML cells

Leukemia Research
2017 | Journal article | Author
Part of ISSN: 0145-2126
EID:

2-s2.0-85015685025

WOSUID:

000405374700008

Contributors: Sadras, Teresa; Perugini, Michelle; Kok, Chung H; Ramshaw, Hayley S; Richard D'Andrea
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The University of South Australia

Self-reverting mutations partially correct the blood phenotype in a diamond blackfan anemia patient

Haematologica
2017 | Journal article | Author
Part of ISSN: 0390-6078
EID:

2-s2.0-85037057515

WOSUID:

000416867100012

Contributors: Bray, Sarah CE; Moore, Sarah; Barnett, Christopher; Yeoman, Alexandra L; George, Amee J; Young, Chun Chun; To, Luen Bik; Lawrence, David M; Richard D'Andrea; Saxon, Ben et al.
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The University of South Australia

Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia

Blood
2017 | Journal article | Author
Part of ISSN: 0006-4971
EID:

2-s2.0-85015282085

WOSUID:

000397017100015

Contributors: John Toubia; Lewis, Alexander C; Pitson, Stuart M; Richard D'Andrea; Thomas, Daniel; Lopez, Angel F; Lewis, Ian D; Saumya Samaraweera; Powell, Jason A; Ramshaw, Hayley S et al.
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The University of South Australia

Conditional knockout mice demonstrate function of Klf5 as a myeloid transcription factor

Blood
2016 | Journal article | Author
Part of ISSN: 0006-4971
EID:

2-s2.0-85016122360

WOSUID:

000379249600013

Contributors: Richard D'Andrea; Diakiw, Sonya; Brown, Anna L; Shahrin, Nur Hezrin; Dent, Lindsay A
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The University of South Australia

Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia

Nature medicine
2016 | Journal article | Author
Part of ISSN: 1078-8956
EID:

2-s2.0-84975321367

WOSUID:

000379366900018

Contributors: Garrett-Bakelman, Francine E; Brown, Anna L; Richard D'Andrea; Chung, Stephen S; Li, Sheng; Sanders, Mathijs A; Mason, Christopher E
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The University of South Australia

Gaq signaling is required for the maintenance of MLL-AF9-induced acute myeloid leukemia

Leukemia
2016 | Journal article | Author
Part of ISSN: 0887-6924
EID:

2-s2.0-84959202392

WOSUID:

000380826400014

Contributors: Liu, Bing; Voli, Florida; Lewis, Ian D; Norris, Murray D; Liu, Tao; Wang, Jenny Yingzi; Gonzales-Aloy, Estrella; Richard D'Andrea; Yi, Hangyu; So, Chi Wai Eric et al.
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The University of South Australia

Impaired haematopoietic stem cell differentiation and enhanced skewing towards myeloid progenitors in aged caspase-2-deficient mice

Cell death and disease
2016 | Journal article | Author
Part of ISSN: 2041-4889
EID:

2-s2.0-85001976719

WOSUID:

000391815800027

Contributors: Hiwase, Devendra K; Shahrin, Nur Hezrin; Sladojevic, Nikolina; Loretta Dorstyn; Dawar, Swati; Richard D'Andrea; Sharad Kumar
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The University of South Australia

Masked polycythaemia vera is genetically intermediate between JAK2V617F mutated essential thrombocythaemia and overt polycythaemia vera

Blood cancer journal
2016 | Journal article | Author
Part of ISSN: 2044-5385
EID:

2-s2.0-85044861404

WOSUID:

000382114300005

Contributors: Tiong, IS; Richard D'Andrea; Ross, DM; Tran Nguyen; Ambler, K; Debora Casolari; Van Velzen, MJM
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The University of South Australia

Novel germ line DDX41 mutations define families with a lower age of MDS/AML onset, and lymphoid malignancies

Blood
2016 | Journal article | Author
Part of ISSN: 0006-4971
EID:

2-s2.0-84960389184

WOSUID:

000373397800012

Contributors: Phung, Connie; Richard D'Andrea; Brown, Anna L; Lewinsohn, Maya; Chong, Chan-Eng; Scott, Hamish S; Weinel, Luke M
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The University of South Australia

The role of Wnt/ss-Catenin signaling in normal and malignant hematopoiesis

Journal of blood research & hematologic diseases
2016 | Journal article | Author
Contributors: White, Deborah L; Sadras, Teresa; Richard D'Andrea
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The University of South Australia

A tale of two siblings: two cases of AML arising from a single pre-leukemic DNMT3A mutant clone

Leukemia
2015 | Journal article | Author
Part of ISSN: 0887-6924
EID:

2-s2.0-84925624634

WOSUID:

000362507600017

Contributors: Parker, WT; Brown, AL; Hiwase, DK; Feng, J; Zawitkowski, M; Beligaswatte, A; Cheetham, GD; Hamish S Scott; To, LB; Lewis, ID et al.
Source: check_circle
The University of South Australia

Hypoxia inducible factor (HIF)-2a accelerates disease progression in mouse models of leukemia and lymphoma but is not a poor prognosis factor in human AML

Leukemia
2015 | Journal article | Author
Part of ISSN: 0887-6924
EID:

2-s2.0-84943587963

WOSUID:

000362507600014

Contributors: Zannettino, AC; Engler, GA; Nowlan, B; Lewis, ID; Brown, Alex; Pattabiraman, D; Richard D'Andrea; Diakiw, SM; Levesque, JP; Helwani, FM et al.
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The University of South Australia

Investigation of a novel cyclin-dependent-kinase (CDK) inhibitor Cdki-73 as an effective treatment option for MLL-AML

Blood
2015 | Journal article | Author
Part of ISSN: 0006-4971
WOSUID:

000368019004165

Contributors: Lock, Richard B; To, Luen Bik; Bray, Sarah C; Iarossi, Diana; Li, Ka Leung; Muhammed Hamidur Rahaman; Lewis, Ian D; Noll, Ben; Richard D'Andrea; Shudong Wang et al.
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The University of South Australia

Dynamic evolution of clonal epialleles revealed by methclone

Genome biology
2014 | Journal article | Author
Part of ISSN: 1465-6906
EID:

2-s2.0-84929173375

WOSUID:

000346604700024

Contributors: Richard D'Andrea; Garrett-Bakelman, Francine; Lewis, Ian D; Mason, Christopher; To, Bik L; Levine, Ross; Carroll, Martin; Li, Sheng; Melnick, Ari; Perl, Alexander E et al.
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The University of South Australia

Interleukin-3-mediated regulation of Beta-catenin in myeloid transformation and acute myeloid leukemia

Journal of Leukocyte Biology
2014 | Journal article | Author
Part of ISSN: 0741-5400
EID:

2-s2.0-84903544386

WOSUID:

000337902100011

Contributors: Perugini, Michelle; To, Luen B; Lewis, Ian D; Samuel, Michael S; Lopez, Angel F; Brumatti, Gabriela; Iarossi, Diana G; Heatley, Susan L; Kok, Chung H; Ramshaw, Hayley S et al.
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The University of South Australia

An optimized algorithm for detecting and annotating regional differential methylation

BMC bioinformatics
2013 | Journal article | Author
Part of ISSN: 1471-2105
EID:

2-s2.0-84876130617

WOSUID:

000318816300010

Contributors: Mason, Christopher E; Richard D'Andrea; Melnick, Ari; Brown, Anna L; Lewis, Ian.D; To, Bik L; Li, Sheng; Levine, Ross; Akalin, Altuna; Zumbo, Paul et al.
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The University of South Australia

Dual epigenetic targeting with panobinostat and azacitidine in acute myeloid leukemia and high-risk myelodysplastic syndrome

Blood cancer journal
2013 | Journal article | Author
Part of ISSN: 2044-5385
EID:

2-s2.0-84892413294

WOSUID:

000331402600001

Contributors: Avery, S; Spencer, A; Wei, A; Tan, P; Walker, P; Cummings, N; Mollee, P; Mithraprabhu, S; Reed, K; Patil, S et al.
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The University of South Australia

GADD45A methylation predicts poor overall survival in acute myeloid leukemia and is associated with IDH1/2 and DNMT3A mutations

Leukemia
2013 | Journal article | Author
Part of ISSN: 0887-6924
EID:

2-s2.0-84880312982

WOSUID:

000321614000021

Contributors: Danner, S; Kok, C; Diakiw, SM; Bardy, PG; Iarossi, D; Cummings, N; Perugini, M; Brown, AL; Richard D'Andrea; Lewis, ID et al.
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The University of South Australia

HoxA9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of HoxA9-dependent leukemia

Oncotarget
2013 | Journal article | Author
Part of ISSN: 1949-2553
EID:

2-s2.0-84890238768

WOSUID:

000327664900011

Contributors: Richard D'Andrea; Brumatti, Gabriela; Jabbour, Anissa M; Bilardi, Rebecca A; Okamoto, Toru; Salmanidis, Marika; Bouillet, Philippe; Silke, Natasha; Visser, Jolanda; Glaser, Stefan P et al.
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The University of South Australia

Low GFI1 expression in white blood cells of CP-CML patients at diagnosis is strongly associated with subsequent blastic transformation

Leukemia
2013 | Journal article | Author
Part of ISSN: 0887-6924
EID:

2-s2.0-84878916342

WOSUID:

000319917500033

Contributors: Leclercq, T; White, DL; Hughes, TP; Kok, CH; Watkins, DB; Richard D'Andrea
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The University of South Australia

Methylation of KLF5 contributes to reduced expression in acute myeloid leukaemia and is associated with poor overall survival

British journal of haematology
2013 | Journal article | Author
Part of ISSN: 0007-1048
EID:

2-s2.0-84878485138

WOSUID:

000319827100016

Contributors: To, Luen Bik; Perugini, Michelle; Engler, Grant A; Wei, Andrew H; Richard D'Andrea; Cummings, Nik; Kok, Chung H; Brown, Anna L; Lewis, Ian D; Diakiw, Sonya M
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The University of South Australia

NPM1 mutations occur rarely or not at all in chronic myeloid leukaemia patients in chronic phase or blast crisis

Leukemia
2013 | Journal article | Author
Part of ISSN: 0887-6924
EID:

2-s2.0-84873570647

WOSUID:

000315553600028

Contributors: White, DL; Hughes, TP; Richard D'Andrea; Watkins, DB
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The University of South Australia

Nutlin-3a efficacy in sarcoma predicted by transcriptomic and epigenetic profiling

Cancer research
2013 | Journal article | Author
Part of ISSN: 0008-5472
EID:

2-s2.0-84893837391

WOSUID:

000331073900028

Contributors: Pishas, Kathleen I; Evdokiou, Andreas; Perugini, Michelle; Whitfield, Robert J; David Lawrence; Neuhaus, Susan J; Manavis, Jim; Ho, Kristen; Thomas, David M; Mayo, Bronwen J et al.
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The University of South Australia

Signalling by the ssc family of cytokines

Cytokine & growth factor reviews
2013 | Journal article | Author
Part of ISSN: 1359-6101
EID:

2-s2.0-84881254509

WOSUID:

000322414000003

Contributors: Perugini, Michelle; Nero, Tracy L; Dhagat, Urmi; Richard D'Andrea; Hughes, Timothy; Timothy Hercus; Kan, Winnie LT; Lopez, Angel F; Ekert, Paul G; Broughton, Sophie E et al.
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The University of South Australia

The double life of KLF5: opposing roles in regulation of gene-expression, cellular function, and transformation

IUBMB life
2013 | Journal article | Author
Part of ISSN: 1521-6543
EID:

2-s2.0-84891276839

WOSUID:

000328742300006

Contributors: Richard D'Andrea; Brown, Anna L; Diakiw, Sonya
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The University of South Australia

The preferential occurrence of FLT3-TKD mutations in inv(16) AML and impact on survival outcome: a combined analysis of 1053 core-binding factor AML patients

British journal of haematology
2013 | Journal article | Author
Part of ISSN: 0007-1048
EID:

2-s2.0-84873079171

WOSUID:

000314068100017

Contributors: Lewis, Ian D; Brown, Anna L; Richard D'Andrea; Iarossi, Diana G; Perugini, Michelle; Kok, Chung H
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The University of South Australia
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