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ResearcherID: K-8835-2014

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Employment (2)

Consejo Superior de Investigaciones Científicas: Madrid, ES

2015-12-01 to present | Doctor (Quimica Médica)
Employment
Source: Self-asserted source
Maria Angeles Bonache

Consejo Superior de Investigaciones Cientificas: Madrid, Madrid, ES

2009 to 2015-11-30 | Doctor (Instituto de Química Médica)
Employment
Source: Self-asserted source
Maria Angeles Bonache

Education and qualifications (1)

Universidad Complutense de Madrid: Madrid, Comunidad de Madrid, ES

2005-04-04 to present | Doctor
Education
Source: Self-asserted source
Maria Angeles Bonache

Works (19)

Phenylalanine-derived β-lactam TRPM8 antagonists: revisiting configuration and new benzoyl derivatives

Exploration of Drug Science
2025-01-13 | Journal article
DOI: 10.37349/eds.2025.100882
Contributors: Cristina Martín-Escura; Maria Angeles Bonache; Alicia Medina-Peris; Thomas Voets; Antonio Ferrer-Montiel; Asia Fernández-Carvajal; Rosario González-Muñiz
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Skeletal Transformations Observed in the Reaction of a Tricyclic Thymine Nucleoside with Dicarbonyl Compounds

ACS Omega
2024 | Journal article
DOI: 10.1021/ACSOMEGA.4C02553
WOSUID: WOS:001291114100001
Contributors: Bonache, Maria-Cruz; Doyaguez, Elisa G.; Benito-Arenas, Raul; Bonache, M. Angeles; Jimeno, Maria-Luisa; San-Felix, Ana
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IQM-22110, a new selective inhibitor of KChIP3 and its electrophysiological effects on K<sub>v</sub>4.3, K<sub>v</sub>4.3/KChIP3 and K<sub>v</sub>4.3/KChIP2 currents

Biophysical Journal
2023 | Journal article
WOSUID: WOS:000989629701362
Contributors: Socuellamos, Paula G.; De Benito-Bueno, Angela; Ropero, Maria; Diez, Sara; Elizalde, Pablo; Angeles Bonache, M.; Viedma, Carmen; Martin-Martinez, Mercedes; Gutierrez-Rodriguez, Marta; Valenzuela, Carmen
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SARS-CoV-2 main protease inhibitors: What is moving in the field of peptides and peptidomimetics?

Journal of Peptide Science
2023 | Journal article
DOI: 10.1002/PSC.3467
WOSUID: WOS:000899920800001
Contributors: Algar-Lizana, Sergio; Angeles Bonache, Maria; Gonzalez-Muniz, Rosario
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β-Lactam TRPM8 Antagonists Derived from Phe-Phenylalaninol Conjugates: Structure-Activity Relationships and Antiallodynic Activity

International Journal of Molecular Sciences
2023 | Journal article
DOI: 10.3390/IJMS241914894
WOSUID: WOS:001089609200001
Contributors: Martin-Escura, Cristina; Bonache, M. angeles; Medina, Jessy A.; Medina-Peris, Alicia; De Andres-Lopez, Jorge; Gonzalez-Rodriguez, Sara; Kerselaers, Sara; Fernandez-Ballester, Gregorio; Voets, Thomas; Ferrer-Montiel, Antonio et al.
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Amino acid-derived β-lactams: TRPM8 antagonists with analgesic activity in different pain models

Journal of Peptide Science
2022 | Journal article
WOSUID: WOS:000968566400229
Contributors: Gonzalez-Muniz, Rosario; Martin-Escura, Cristina; Angeles Bonache, M.; Medina-Peris, Alicia; de la Torre Martinez, Roberto; Olivos-Ore, Luis; Victoria Barahona, M.; Gonzalez-Rodriguez, Sara; Fernandez-Ballester, Gregorio; Gomez-Monterrey, Isabel et al.
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DD04107-Derived neuronal exocytosis inhibitor peptides: Evidences for synaptotagmin-1 as a putative target

Bioorganic Chemistry
2021 | Journal article
DOI: 10.1016/J.BIOORG.2021.105231
WOSUID: WOS:000704036500011
Contributors: Butron, Daniel; Zamora-Carreras, Hector; Devesa, Isabel; Trevino, Miguel A.; Abian, Olga; Velazquez-Campoy, Adrian; Bonache, M. Angeles; Lagartera, Laura; Martin-Martinez, Mercedes; Gonzalez-Rodriguez, Sara et al.
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Modulating Protein-Protein Interactions by Cyclic and Macrocyclic Peptides. Prominent Strategies and Examples

Molecules
2021 | Journal article
DOI: 10.3390/MOLECULES26020445
WOSUID: WOS:000611495600001
Contributors: Gonzalez-Muniz, Rosario; Bonache, Maria Angeles; Perez de Vega, Maria Jesus
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Phenylalanine-Derived β-Lactam TRPM8 Modulators. Configuration Effect on the Antagonist Activity

International Journal of Molecular Sciences
2021 | Journal article
DOI: 10.3390/IJMS22052370
WOSUID: WOS:000628317800001
Contributors: Bonache, Maria Angeles; Llabres, Pedro Juan; Martin-Escura, Cristina; de la Torre-martinez, Roberto; Medina-Peris, Alicia; Butron, Laura; Gomez-Monterrey, Isabel; Roa, Ana Maria; Fernandez-Ballester, Gregorio; Ferrer-Montiel, Antonio et al.
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Highly functionalized β-lactams and 2-ketopiperazines as TRPM8 antagonists with antiallodynic activity

Scientific Reports
2020 | Journal article
DOI: 10.1038/S41598-020-70691-X
WOSUID: WOS:000567058100007
Contributors: Angeles Bonache, M.; Martin-Escura, Cristina; de la Torre Martinez, Roberto; Medina, Alicia; Gonzalez-Rodriguez, Sara; Francesch, Andres; Cuevas, Carmen; Maria Roa, Ana; Fernandez-Ballester, Gregorio; Ferrer-Montiel, Antonio et al.
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Recent Progress in TRPM8 Modulation: An Update

International Journal of Molecular Sciences
2019-05-28 | Journal article
DOI: 10.3390/ijms20112618
Contributors: Rosario González-Muñiz; M. Angeles Bonache; Cristina Martín-Escura; Isabel Gómez-Monterrey
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Small Library of Triazolyl Polyphenols Correlating Antioxidant Activity and Stability with Number and Position of Hydroxyl Groups

ACS Combinatorial Science
2018 | Journal article
DOI: 10.1021/ACSCOMBSCI.8B00118
WOSUID: WOS:000453108700002
Contributors: Angeles Bonache, Ma; Moreno-Fernandez, Silvia; Miguel, Marta; Sabater-Munoz, Beatriz; Gonzalez-Muniz, Rosario
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Unraveling the Mechanism of Action of the Analgesic Peptdie DD04107. Synaptotagmin-1 as a Putative Target

Journal of Peptide Science
2018 | Journal article
WOSUID: WOS:000447650300284
Contributors: Butron, Daniel; Carrera-Zamora, Hector; Devesa, Isabel; Trevino, Miguel A.; Angeles Bonache, M.; Velazquez-Campoy, Adrian; Ferrer-Montiel, Antonio; Angeles Jimenez, M.; Gonzalez-Muniz, Rosario
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Disrupting VEGF-VEGFR1 Interaction: De Novo Designed Linear Helical Peptides to Mimic the VEGF<sub>13-25</sub> Fragment

Molecules
2017 | Journal article
DOI: 10.3390/MOLECULES22111846
WOSUID: WOS:000416528400048
Contributors: Balsera, Beatriz; Angeles Bonache, M.; Reille-Seroussi, Marie; Gagey-Eilstein, Nathalie; Vidal, Michel; Gonzalez-Muniz, Rosario; Jesus Perez de Vega, Maria
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Identification, functional gastrointestinal stability and molecular docking studies of lentil peptides with dual antioxidant and angiotensin I converting enzyme inhibitory activities

Food Chemistry
2017 | Journal article
DOI: 10.1016/J.FOODCHEM.2016.10.087
WOSUID: WOS:000389909100059
Contributors: Garcia-Mora, Patricia; Martin-Martinez, Mercedes; Angeles Bonache, Maria; Gonzalez-Muniz, Rosario; Penas, Elena; Frias, Juana; Martinez-Villaluenga, Cristina
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Synthesis, high-throughput screening and pharmacological characterization of β-lactam derivatives as TRPM8 antagonists

Scientific Reports
2017 | Journal article
DOI: 10.1038/S41598-017-10913-X
WOSUID: WOS:000409561800019
Contributors: de la Torre-Martinez, Roberto; Angeles Bonache, M.; Llabres-Campaner, Pedro J.; Balsera, Beatriz; Fernandez-Carvajal, Asia; Fernandez-Ballester, Gregorio; Ferrer-Montiel, Antonio; Perez de Vega, M. Jesus; Gonzalez-Muniz, Rosario
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Experimental and Theoretical Studies on the Rearrangement of 2-Oxoazepane α,α-Amino Acids into 2′-Oxopiperidine β<SUP>2,3,3</SUP>-Amino Acids: An Example of Intramolecular Catalysis

Chemistry - A European Journal
2015 | Journal article
DOI: 10.1002/CHEM.201405640
WOSUID: WOS:000348510400028
Contributors: Nunez-Villanueva, Diego; Angeles Bonache, M.; Lozano, Laura; Infantes, Lourdes; Elguero, Jose; Alkorta, Ibon; Teresa Garcia-Lopez, M.; Gonzalez-Muniz, Rosario; Martin-Martinez, Mercedes
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Memory of chirality in the enantioselective synthesis of β-lactams derived from amino acids.: Influence of the reaction conditions

Synlett
2003 | Journal article
WOSUID: WOS:000183377000021
Contributors: Bonache, MA; Gerona-Navarro, G; Martín-Martínez, M; García-López, MT; López, P; Cativiela, C; González-Muñiz, R
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Entry to new conformationally constrained amino acids.: First synthesis of 3-unsubstituted 4-alkyl-4-carboxy-2-azetidinone derivatives via an intramolecular N<SUP>α</SUP>-C<SUP>α</SUP>-cyclization strategy

The Journal of Organic Chemistry
2001 | Journal article
DOI: 10.1021/JO015559B
WOSUID: WOS:000168907700039
Contributors: Gerona-Navarro, G; Bonache, MA; Herranz, R; García-López, MT; González-Muñiz, R
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