Personal information

Japan

Activities

Employment (4)

Jichi Medical University: Shimotsuke, Tochigi, JP

2018-11-01 to present | Assistant Professor / Lecturer (Division of Gene Therapeutics, Center for Molecular Medicine)
Employment
Source: Self-asserted source
Kenji Ohba

Hokkaido University: Sapporp, Hokkaido, JP

2015-03-16 to 2018-10-31 | Project Assistant Professor (Division of Molecular Oncology, Institute for Genetic Medicine)
Employment
Source: Self-asserted source
Kenji Ohba

National University of Singapore: Singapore, Singapore, SG

2010-04-01 to 2015-03-15 | Research Fellow (Department of Microbiology, Yong Loo Lin School of Medicine)
Employment
Source: Self-asserted source
Kenji Ohba

National Institute of Infectious Diseases: Tokyo, Tôkyô, JP

2008-04-01 to 2010-03-31 | Postdoctoral Fellow (AIDS Research Center)
Employment
Source: Self-asserted source
Kenji Ohba

Education and qualifications (3)

Tokyo Medical and Dental University: Bunkyo-ku, Tokyo, JP

2004-04-01 to 2008-03-31 | Ph.D. (Medicine)
Qualification
Source: Self-asserted source
Kenji Ohba

Yokohama City University: Yokohama, Kanagawa, JP

2002-04-01 to 2004-03-31 | Master (Medical Science)
Qualification
Source: Self-asserted source
Kenji Ohba

Rikkyo University: Toshiba-ku, Tokyo, JP

1998-04-01 to 2002-03-31 | Bachelor of Science (Life Science, Chemistry)
Qualification
Source: Self-asserted source
Kenji Ohba

Works (32)

Adeno-associated Virus-mediated Ezh2 Knockdown Reduced the Increment of Newborn Neurons Induced by Forebrain Ischemia in Gerbil Dentate Gyrus

Molecular Neurobiology
2024-11 | Journal article
Contributors: Yoshihide Sehara; Yuki Hashimotodani; Ryota Watano; Kenji Ohba; Ryosuke Uchibori; Kuniko Shimazaki; Kensuke Kawai; Hiroaki Mizukami
Source: check_circle
Crossref

Protocol for producing an adeno-associated virus vector by controlling capsid expression timing

STAR Protocols
2023-12 | Journal article
Contributors: Kenji Ohba; Hiroaki Mizukami
Source: check_circle
Crossref

Therapeutic strategy for Fabry disease by intravenous administration of adeno‐associated virus 2 or 9 in α‐galactosidase A‐deficient mice

The Journal of Gene Medicine
2023-12 | Journal article
Contributors: Yuka Hayashi; Yoshihide Sehara; Ryota Watano; Kenji Ohba; Yuki Takayanagi; Kazuhiro Muramatsu; Yoshio Sakiyama; Hiroaki Mizukami
Source: check_circle
Crossref

Adeno-associated virus vector system controlling capsid expression improves viral quantity and quality

iScience
2023-04 | Journal article
Contributors: Kenji Ohba; Yoshihide Sehara; Tatsuji Enoki; Junichi Mineno; Keiya Ozawa; Hiroaki Mizukami
Source: check_circle
Crossref

Epithelial cells remove precancerous cells by cell competition via MHC class I–LILRB3 interaction

Nature Immunology
2021-11 | Journal article
Part of ISSN: 1529-2908
Part of ISSN: 1529-2916
Source: Self-asserted source
Kenji Ohba
grade
Preferred source (of 2)‎

Higher Transduction Efficiency of AAV5 to Neural Stem Cells and Immature Neurons in Gerbil Dentate Gyrus Compared to AAV2 and rh10.

Human gene therapy
2021-08 | Journal article
Contributors: Sehara Y; Hayashi Y; Ohba K; Uchibori R; Urabe M; Inutsuka A; Shimazaki K; Kawai K; Mizukami H
Source: Self-asserted source
Kenji Ohba via Europe PubMed Central

The CD44/COL17A1 pathway promotes the formation of multilayered, transformed epithelia.

Current biology : CB
2021-06 | Journal article
Contributors: Kozawa K; Sekai M; Ohba K; Ito S; Sako H; Maruyama T; Kakeno M; Shirai T; Kuromiya K; Kamasaki T et al.
Source: Self-asserted source
Kenji Ohba via Europe PubMed Central

Characterization of RyDEN (C19orf66) as an Interferon-Stimulated Cellular Inhibitor against Dengue Virus Replication

PLoS Pathog
2016 | Journal article
Contributors: Suzuki, Y.; Chin, W. X.; Han, Q.; Ichiyama, K.; Lee, C. H.; Eyo, Z. W.; Ebina, H.; Takahashi, H.; Takahashi, C.; Tan, B. H. et al.
Source: Self-asserted source
Kenji Ohba via ResearcherID

Cooperative Orthogonal Macromolecular Assemblies with Broad Spectrum Antiviral Activity, High Selectivity, and Resistance Mitigation

Macromolecules
2016 | Journal article
WOSUID:

WOS:000374195600025

Contributors: Ichiyama, Koji; Yang, Chuan; Chandrasekaran, Lakshmi; Liu, Shaoqiong; Rong, Lijun; Zhao, Yue; Gao, Shujun; Lee, Ashlynn; Ohba, Kenji; Suzuki, Youichi et al.
Source: Self-asserted source
Kenji Ohba via ResearcherID

Macrophage response to oncolytic paramyxoviruses potentiates virus-mediated tumor cell killing

Eur J Immunol
2016 | Journal article
Contributors: Tan, D. Q.; Zhang, L.; Ohba, K.; Ye, M.; Ichiyama, K.; Yamamoto, N.
Source: Self-asserted source
Kenji Ohba via ResearcherID

Cancellers - Exploring the Possibility of Receptor Decoy Traps as a Superior Anti-Retroviral Strategy

Curr Drug Targets
2015 | Journal article
SOURCE-WORK-ID:

0404190102624-21

Contributors: Jeremiah, S. S.; Ohba, K.; Yamamoto, N.
Source: Self-asserted source
Kenji Ohba via ResearcherID

Combination of vaccine-strain measles and mumps virus synergistically kills a wide range of human hematological cancer cells: Special focus on acute myeloid leukemia

Cancer Lett
2014 | Journal article
DOI:

10.1016/j.canlet.2014.08.034 10.1016/j.canlet.2014.08.034. Epub 2014 Sep 1.

Contributors: Zhang, L. F.; Tan, D. Q.; Jeyasekharan, A. D.; Hsieh, W. S.; Ho, A. S.; Ichiyama, K.; Ye, M.; Pang, B.; Ohba, K.; Liu, X. et al.
Source: Self-asserted source
Kenji Ohba via ResearcherID

In vivo and in vitro studies suggest a possible involvement of HPV infection in the early stage of breast carcinogenesis via APOBEC3B induction

PLoS One
2014 | Journal article
DOI:

10.1371/journal.pone.0097787 10.1371/journal.pone.0097787. eCollection 2014.

Contributors: Ohba, K.; Ichiyama, K.; Yajima, M.; Gemma, N.; Nikaido, M.; Wu, Q.; Chong, P.; Mori, S.; Yamamoto, R.; Wong, J. E. et al.
Source: Self-asserted source
Kenji Ohba via ResearcherID

Effects of DNA binding of the zinc finger and linkers for domain fusion on the catalytic activity of sequence-specific chimeric recombinases determined by a facile fluorescent system

Biochemistry
2012 | Journal article
DOI:

10.1021/bi201878x 10.1021/bi201878x. Epub 2012 Feb 8.

Contributors: Nomura, W.; Masuda, A.; Ohba, K.; Urabe, A.; Ito, N.; Ryo, A.; Yamamoto, N.; Tamamura, H.
Source: Self-asserted source
Kenji Ohba via ResearcherID

Remodeling of dynamic structures of HIV-1 envelope proteins leads to synthetic antigen molecules inducing neutralizing antibodies

Bioconjug Chem
2010 | Journal article
DOI:

10.1021/bc900502z 10.1021/bc900502z.

Contributors: Nakahara, T.; Nomura, W.; Ohba, K.; Ohya, A.; Tanaka, T.; Hashimoto, C.; Narumi, T.; Murakami, T.; Yamamoto, N.; Tamamura, H.
Source: Self-asserted source
Kenji Ohba via ResearcherID

BCA2/Rabring7 promotes tetherin-dependent HIV-1 restriction

PLoS Pathog
2009 | Journal article
DOI:

10.1371/journal.ppat.1000700 10.1371/journal.ppat.1000700. Epub 2009 Dec 18.

Contributors: Miyakawa, K.; Ryo, A.; Murakami, T.; Ohba, K.; Yamaoka, S.; Fukuda, M.; Guatelli, J.; Yamamoto, N.
Source: Self-asserted source
Kenji Ohba via ResearcherID

Fluorogenically active leucine zipper peptides as tag-probe pairs for protein imaging in living cells

Angew Chem Int Ed Engl
2009 | Journal article
DOI:

10.1002/anie.200903183 10.1002/anie.200903183.

Contributors: Tsutsumi, H.; Nomura, W.; Abe, S.; Mino, T.; Masuda, A.; Ohashi, N.; Tanaka, T.; Ohba, K.; Yamamoto, N.; Akiyoshi, K. et al.
Source: Self-asserted source
Kenji Ohba via ResearcherID

Follicular dendritic cells activate HIV-1 replication in monocytes/macrophages through a juxtacrine mechanism mediated by P-selectin glycoprotein ligand 1

J Immunol
2009 | Journal article
DOI:

10.4049/jimmunol.0900371 10.4049/jimmunol.0900371.

Contributors: Ohba, K.; Ryo, A.; Dewan, M. Z.; Nishi, M.; Naito, T.; Qi, X.; Inagaki, Y.; Nagashima, Y.; Tanaka, Y.; Okamoto, T. et al.
Source: Self-asserted source
Kenji Ohba via ResearcherID

Requirement for microtubule integrity in the SOCS1-mediated intracellular dynamics of HIV-1 Gag

FEBS Lett
2009 | Journal article
DOI:

10.1016/j.febslet.2009.03.041 10.1016/j.febslet.2009.03.041. Epub 2009 Mar 25.

Contributors: Nishi, M.; Ryo, A.; Tsurutani, N.; Ohba, K.; Sawasaki, T.; Morishita, R.; Perrem, K.; Aoki, I.; Morikawa, Y.; Yamamoto, N.
Source: Self-asserted source
Kenji Ohba via ResearcherID

Fluorophore labeling enables imaging and evaluation of specific CXCR4-ligand interaction at the cell membrane for fluorescence-based screening

Bioconjug Chem
2008 | Journal article
DOI:

10.1021/bc800216p 10.1021/bc800216p. Epub 2008 Aug 16.

Contributors: Nomura, W.; Tanabe, Y.; Tsutsumi, H.; Tanaka, T.; Ohba, K.; Yamamoto, N.; Tamamura, H.
Source: Self-asserted source
Kenji Ohba via ResearcherID

SOCS1 is an inducible host factor during HIV-1 infection and regulates the intracellular trafficking and stability of HIV-1 Gag

Proc Natl Acad Sci U S A
2008 | Journal article
DOI:

10.1073/pnas.0704831105 10.1073/pnas.0704831105. Epub 2008 Jan 2.

Contributors: Ryo, A.; Tsurutani, N.; Ohba, K.; Kimura, R.; Komano, J.; Nishi, M.; Soeda, H.; Hattori, S.; Perrem, K.; Yamamoto, M. et al.
Source: Self-asserted source
Kenji Ohba via ResearcherID

Structure-activity relationship study of CXCR4 antagonists bearing the cyclic pentapeptide scaffold: identification of the new pharmacophore

Org Biomol Chem
2008 | Journal article
DOI:

10.1039/b812029c 10.1039/b812029c. Epub 2008 Oct 17.

Contributors: Tanaka, T.; Tsutsumi, H.; Nomura, W.; Tanabe, Y.; Ohashi, N.; Esaka, A.; Ochiai, C.; Sato, J.; Itotani, K.; Murakami, T. et al.
Source: Self-asserted source
Kenji Ohba via ResearcherID

Efficient induction of HIV-1 replication in latently infected cells through contact with CD4+ T cells: involvement of NF-kappaB activation

Virology
2007 | Journal article
DOI:

10.1016/j.virol.2006.11.014

Contributors: Qi, X.; Koya, Y.; Saitoh, T.; Saitoh, Y.; Shimizu, S.; Ohba, K.; Yamamoto, N.; Yamaoka, S.
Source: Self-asserted source
Kenji Ohba via ResearcherID

Mutant influenza A virus nucleoprotein is preferentially localized in the cytoplasm and its immunization in mice shows higher immunogenicity and cross-reactivity

Vaccine
2007 | Journal article
DOI:

10.1016/j.vaccine.2007.02.074

Contributors: Ohba, K.; Yoshida, S.; Zahidunnabi Dewan, M.; Shimura, H.; Sakamaki, N.; Takeshita, F.; Yamamoto, N.; Okuda, K.
Source: Self-asserted source
Kenji Ohba via ResearcherID

A fused gene of nucleoprotein (NP) and herpes simplex virus genes (VP22) induces highly protective immunity against different subtypes of influenza virus

Virology
2006 | Journal article
DOI:

10.1016/j.virol.2006.04.015

Contributors: Saha, S.; Yoshida, S.; Ohba, K.; Matsui, K.; Matsuda, T.; Takeshita, F.; Umeda, K.; Tamura, Y.; Okuda, K.; Klinman, D. et al.
Source: Self-asserted source
Kenji Ohba via ResearcherID

Stromal cell-derived factor-1 and CXCR4 receptor interaction in tumor growth and metastasis of breast cancer

Biomed Pharmacother
2006 | Journal article
DOI:

10.1016/j.biopha.2006.06.004

Contributors: Dewan, M. Z.; Ahmed, S.; Iwasaki, Y.; Ohba, K.; Toi, M.; Yamamoto, N.
Source: Self-asserted source
Kenji Ohba via ResearcherID

Mouse serum factor(s) down-modulate the CD4 and CXCR4 molecules on human T cells conferring resistance to HIV infection in NOG mice

Med Microbiol Immunol
2005 | Journal article
DOI:

10.1007/s00430-004-0234-1

Contributors: Dewan, M. Z.; Terashima, K.; Ahmed, S.; Ohba, K.; Taruishi, M.; Yamamoto, N.
Source: Self-asserted source
Kenji Ohba via ResearcherID

Natural killer cells in breast cancer cell growth and metastasis in SCID mice

Biomed Pharmacother
2005 | Journal article
SOURCE-WORK-ID:

0410150446896-16

Contributors: Dewan, M. Z.; Terunuma, H.; Ahmed, S.; Ohba, K.; Takada, M.; Tanaka, Y.; Toi, M.; Yamamoto, N.
Source: Self-asserted source
Kenji Ohba via ResearcherID

Natural killer cells in breast cancer cell growth and metastasis in SCID mice

Biomed Pharmacother
2005 | Journal article
SOURCE-WORK-ID:

0404190102625-16

Contributors: Dewan, M. Z.; Terunuma, H.; Ahmed, S.; Ohba, K.; Takada, M.; Tanaka, Y.; Toi, M.; Yamamoto, N.
Source: Self-asserted source
Kenji Ohba via ResearcherID

A DNA vaccine containing inverted terminal repeats from adeno-associated virus increases immunity to HIV

J Gene Med
2003 | Journal article
DOI:

10.1002/jgm.356

Contributors: Xin, K. Q.; Ooki, T.; Jounai, N.; Mizukami, H.; Hamajima, K.; Kojima, Y.; Ohba, K.; Toda, Y.; Hirai, S.; Klinman, D. M. et al.
Source: Self-asserted source
Kenji Ohba via ResearcherID

Contribution of the rev gene to the immunogenicity of DNA vaccines targeting the envelope glycoprotein of HIV

J Gene Med
2003 | Journal article
DOI:

10.1002/jgm.391

Contributors: Jounai, N.; Okuda, K.; Kojima, Y.; Toda, Y.; Hamajima, K.; Ohba, K.; Klinman, D.; Xin, K. Q.
Source: Self-asserted source
Kenji Ohba via ResearcherID

Immunogenicity and protective efficacy of orally administered recombinant Lactococcus lactis expressing surface-bound HIV Env

Blood
2003 | Journal article
DOI:

10.1182/blood-2003-01-0110

Contributors: Xin, K. Q.; Hoshino, Y.; Toda, Y.; Igimi, S.; Kojima, Y.; Jounai, N.; Ohba, K.; Kushiro, A.; Kiwaki, M.; Hamajima, K. et al.
Source: Self-asserted source
Kenji Ohba via ResearcherID