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Works (12)

Glycosphingolipid synthesis mediates immune evasion in KRAS-driven cancer

Nature
2024-09-12 | Journal article
DOI: 10.1038/s41586-024-07787-1
Contributors: Mariluz Soula; Gokhan Unlu; Rachel Welch; Aleksey Chudnovskiy; Beste Uygur; Vyom Shah; Hanan Alwaseem; Paul Bunk; Vishvak Subramanyam; Hsi-Wen Yeh et al.
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Inter-organellar nucleic acid communication by a mitochondrial tRNA regulates nuclear metabolic transcription

2023-09-22 | Preprint
DOI: 10.1101/2023.09.21.558912
Contributors: Christopher Rouya; King Faisal Yambire; Mark L. Derbyshire; Hanan Alwaseem; Sohail F. Tavazoie
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Disruption of proteome by an oncogenic fusion kinase alters metabolism in fibrolamellar hepatocellular carcinoma

Science Advances
2023-06-23 | Journal article
DOI: 10.1126/sciadv.adg7038
Contributors: Solomon N. Levin; Michael D. Tomasini; James Knox; Mahsa Shirani; Bassem Shebl; David Requena; Jackson Clark; Søren Heissel; Hanan Alwaseem; Rodrigo Surjan et al.
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Arginine limitation drives a directed codon-dependent DNA sequence evolution response in colorectal cancer cells

Science Advances
2023-01-06 | Journal article
DOI: 10.1126/sciadv.ade9120
Contributors: Dennis J. Hsu; Jenny Gao; Norihiro Yamaguchi; Alexandra Pinzaru; Qiushuang Wu; Nandan Mandayam; Maria Liberti; Søren Heissel; Hanan Alwaseem; Saeed Tavazoie et al.
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Arginine limitation causes a directed DNA sequence evolution response in colorectal cancer cells

2023-01-02 | Preprint
DOI: 10.1101/2023.01.02.521806
Contributors: Dennis J. Hsu; Jenny Gao; Norihiro Yamaguchi; Alexandra Pinzaru; Nandan Mandayam; Maria Liberti; Søren Heissel; Hanan Alwaseem; Saeed Tavazoie; Sohail F. Tavazoie
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The pupal moulting fluid has evolved social functions in ants

Nature
2022-12-15 | Journal article
DOI: 10.1038/s41586-022-05480-9
Contributors: Orli Snir; Hanan Alwaseem; Søren Heissel; Anurag Sharma; Stephany Valdés-Rodríguez; Thomas S. Carroll; Caroline S. Jiang; Jacopo Razzauti; Daniel J. C. Kronauer
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Nanoparticle‐Mediated Delivery of Micheliolide Analogs to Eliminate Leukemic Stem Cells in the Bone Marrow

Advanced Therapeutics
2022-01 | Journal article
DOI: 10.1002/adtp.202100100
Contributors: Marian A. Ackun‐Farmmer; Hanan Alwaseem; Michele Counts; Andrew Bortz; Simone Giovani; Benjamin J. Frisch; Rudi Fasan; Danielle S. W. Benoit
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Analysis of the mechanosensor channel functionality of TACAN

eLife
2021-08-10 | Journal article
DOI: 10.7554/eLife.71188
Contributors: Yiming Niu; Xiao Tao; George Vaisey; Paul Dominic B Olinares; Hanan Alwaseem; Brian T Chait; Roderick MacKinnon
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A pro-metastatic tRNA fragment drives Nucleolin oligomerization and stabilization of bound metabolic mRNAs

2021-04-26 | Other
DOI: 10.1101/2021.04.26.441477
Contributors: Xuhang Liu; Hanan Alwaseem; Henrik Molina; Bernardo Tavora; Sohail F. Tavazoie
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Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers

Nature Chemical Biology
2020-12 | Journal article
DOI: 10.1038/s41589-020-0613-y
Contributors: Mariluz Soula; Ross A. Weber; Omkar Zilka; Hanan Alwaseem; Konnor La; Frederick Yen; Henrik Molina; Javier Garcia-Bermudez; Derek A. Pratt; Kıvanç Birsoy
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Metabolic coessentiality mapping identifies C12orf49 as a regulator of SREBP processing and cholesterol metabolism

Nature Metabolism
2020-06-01 | Journal article
DOI: 10.1038/s42255-020-0206-9
Contributors: Erol C. Bayraktar; Konnor La; Kara Karpman; Gokhan Unlu; Ceren Ozerdem; Dylan J. Ritter; Hanan Alwaseem; Henrik Molina; Hans-Heinrich Hoffmann; Alec Millner et al.
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Stabilization of the Reductase Domain in the Catalytically Self‐Sufficient Cytochrome P450BM3 by Consensus‐Guided Mutagenesis

ChemBioChem
2018-03-16 | Journal article
DOI: 10.1002/cbic.201700546
Contributors: Gloria Saab‐Rincón; Hanan Alwaseem; Valeria Guzmán‐Luna; Leticia Olvera; Rudi Fasan
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