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Employment (2)

Sun Yat-sen University: Guangzhou, Guangdong, CN

2018-02 to present | Professor (School of Pharmaceutical Sciences)
Employment
Source: Self-asserted source
Junjian Wang

University of California Davis Comprehensive Cancer Center: Sacramento, CA, US

2010-05 to 2018-01 | Postdoctor, Assistant Project Scientist
Employment
Source: Self-asserted source
Junjian Wang

Education and qualifications (3)

Guangzhou Institutes of Biomedicine and Health: Guangzhou, Guangdong, CN

2006-09 to 2009-06 | PhD
Education
Source: Self-asserted source
Junjian Wang

Sun Yat-Sen University: Guangzhou, Guangdong, CN

2002-09 to 2005-06 | MS (Life Sciences)
Education
Source: Self-asserted source
Junjian Wang

Inner Mongolia University: Hohhot, Inner Mongolia, CN

1998-09 to 2002-06 | Bachelor
Education
Source: Self-asserted source
Junjian Wang

Works (50 of 79)

Items per page:
Page 1 of 2

Small protein ERSP encoded by LINC02870 promotes triple negative breast cancer progression via IRE1α/XBP1s activation

Cell Death & Differentiation
2025-01-11 | Journal article | Author
Part of ISSN: 1350-9047
Part of ISSN: 1476-5403
Contributors: Xiaolu Wang; Qianqian Wang; Hong Wang; Guodi Cai; Yana An; Liu Peiqing; HUIHAO ZHOU; Hongwu Chen; Shufeng Ji; Jiantao Ye et al.
Source: Self-asserted source
Junjian Wang

Design, Synthesis, and Biological Evaluation of Novel Diaminopyrimidine Macrocycles as Fourth Generation Reversible EGFR Inhibitors That Overcome Clinical Resistance to Osimertinib Mediated by C797S Mutation

Journal of Medicinal Chemistry
2024-11-13 | Journal article
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Contributors: Shiliang Hu; Linjiang Tong; Qiao Qin; Jiaxin Wen; Yan Li; Fang Feng; Kunzhong Wu; Yang Zhou; Jinsai Shang; Junjian Wang et al.
Source: Self-asserted source
Junjian Wang

Therapeutic targeting ERRγ suppresses metastasis via extracellular matrix remodeling in small cell lung cancer.

EMBO molecular medicine
2024-07-31 | Journal article | Author
Contributors: Wang H; Sun H; Huang J; Zhang Z; Cai G; Wang C; Xiao K; Xiao-Feng Xiong; Zhang J; Liu Peiqing et al.
Source: Self-asserted source
Junjian Wang

Discovery of a Highly Potent Lysine Methyltransferases G9a/NSD2 Dual Inhibitor to Treat Solid Tumors

Journal of Medicinal Chemistry
2024-07-15 | Journal article
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Contributors: Chunju Yang; Bang Li; Zongbo Feng; Huaxuan Li; Hong Yang; Zhenjiao Yang; Li Liu; Qiongyu Shi; Hong Wang; zhong-zhu chen et al.
Source: Self-asserted source
Junjian Wang

Targeting KPNB1 with Genkwadaphnin suppresses gastric cancer progression through the Nur77-mediated signaling pathway.

European journal of pharmacology
2024-05-30 | Journal article
Contributors: Zhang C; Wang X; Cai G; Wang H; Liu Q; Ma S; Sun H; An Y; Miao M; Yin S et al.
Source: Self-asserted source
Junjian Wang

DHODH inhibition represents a therapeutic strategy and improves abiraterone treatment in castration-resistant prostate cancer

Oncogene
2024-05-03 | Journal article
Contributors: Shaoqiang Guo; Miaomiao Miao; Yufeng Wu; Dongyue Pan; Qinyan Wu; Zhanfang Kang; Jianwen Zeng; Guoping Zhong; Chengfei Liu; Junjian Wang
Source: check_circle
Crossref

Genotyping of RB1 status identifies two distinct subtypes in EGFR-mutant lung cancers with SCLC transformation.

Clinical and translational medicine
2024-05-01 | Journal article | Author
Contributors: Jie Huang; Zhang SL; Zhang C; Huang W; Zhang Z; Chen YQ; Su JW; Yan HH; Chen HJ; Yang JJ et al.
Source: Self-asserted source
Junjian Wang

Tumor mitochondrial oxidative phosphorylation stimulated by the nuclear receptor RORγ represents an effective therapeutic opportunity in osteosarcoma.

Cell reports. Medicine
2024-04-24 | Journal article
Contributors: Zheng J; Wang Q; Chen J; Cai G; Zhang Z; Zou H; Zou JX; Liu Q; Ji S; Shao G et al.
Source: Self-asserted source
Junjian Wang

A β-Galactosidase-Activated Fluorogenic Reporter for the Detection of Gastric Cancer In Vivo and in Urine.

Analytical chemistry
2024-04-12 | Journal article
Contributors: Yu M; Meng Z; Yi S; Chen J; Xu W; Ruan B; Wang J; Han F; Jiaguo Huang
Source: Self-asserted source
Junjian Wang

Targeting RORγ inhibits the growth and metastasis of hepatocellular carcinoma.

Molecular therapy : the journal of the American Society of Gene Therapy
2024-02-03 | Journal article
Contributors: Liu Q; Wang J; Sun H; Zhang Z; Wang H; Ma S; Zhang C; Wang Q; Cai G; Zheng J et al.
Source: Self-asserted source
Junjian Wang

Discovery of the First-in-Class RORγ Covalent Inhibitors for Treatment of Castration-Resistant Prostate Cancer

Journal of Medicinal Chemistry
2024-01-16 | Journal article
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Contributors: Wei Fang; Jianwei Zheng; Lin Deng; Yana An; Deqin Rong; Jianwei Wei; Xiao-Feng Xiong; Junjian Wang; Yuanxiang Wang
Source: Self-asserted source
Junjian Wang

Wild-type IDH1 maintains NSCLC stemness and chemoresistance through activation of the serine biosynthetic pathway

Science Translational Medicine
2023-12-13 | Journal article
Contributors: Cheng Zhang; Jiao-jiao Yu; Chen Yang; Zhen-long Yuan; Hui Zeng; Jun-jian Wang; Shuang Shang; Xiao-xi Lv; Xiao-tong Liu; Jing Liu et al.
Source: check_circle
Crossref

DHODH inhibition represents a therapeutic strategy and improves abiraterone treatment in castration-resistant prostate cancer

2023-11-25 | Preprint
Contributors: Junjian Wang; guo shaoqiang; Miao miaomiao; Wu yufeng; Wu Qinyan; Pan dongyue; Kang Zhanfang; Zeng Jianwen; Chengfei Liu; Zhong Guoping
Source: check_circle
Crossref

Flot2 deficiency facilitates B cell-mediated inflammatory responses and endotoxic shock.

Immunology
2023-09-08 | Journal article
Contributors: qin yang; Zhang Z; Chen Z; Wang Y; Chen Y; Zheng J; Li R; Li L; Mo L; Liang Q et al.
Source: Self-asserted source
Junjian Wang

Discovery of a highly potent and orally available importin-β1 inhibitor that overcomes enzalutamide-resistance in advanced prostate cancer

Acta Pharmaceutica Sinica B
2023-07 | Journal article | Author
Part of ISSN: 2211-3835
Contributors: Jia-Luo Huang; Xue-Long Yan; Dong Huang; Lu Gan; Huahua Gao; Run-Zhu Fan; Shen Li; Fang-Yu Yuan; Xinying Zhu; Gui-Hua Tang et al.
Source: Self-asserted source
Junjian Wang

Marine fungus-derived alkaloid inhibits the growth and metastasis of gastric cancer via targeting mTORC1 signaling pathway

Chemico-Biological Interactions
2023-06 | Journal article | Author
Part of ISSN: 0009-2797
Contributors: Shuai Ma; Yiwei Hu; Jianjiao Chen; Xiaojuan Wang; Chenxi Zhang; Qianqian Liu; Guodi Cai; Hong Wang; Jianwei Zheng; Qianqian Wang et al.
Source: Self-asserted source
Junjian Wang

Cytotoxic pyridine alkaloids from a marine-derived fungus Arthrinium arundinis exhibiting apoptosis-inducing activities against small cell lung cancer.

Phytochemistry
2023-06-15 | Journal article
Contributors: Hu Y; Ma S; Pang X; Cong M; Liu Q; Han F; Wang J; Feng W; Liu Y; Wang J
Source: Self-asserted source
Junjian Wang

Cyclohexenone Derivative and Drimane Sesquiterpenes from the Seagrass‐Derived Fungus Aspergillus insuetus

Chemistry & Biodiversity
2023-06-06 | Journal article
Part of ISSN: 1612-1872
Part of ISSN: 1612-1880
Contributors: Zhibo Hu; Junjie Chen; Qianqian Liu; Qilin Wu; Shenhua Chen; Junjian Wang; Jing Li; Lan Liu; Zhizeng Gao
Source: Self-asserted source
Junjian Wang

Structure-Based Design and Characterization of the Highly Potent and Selective Covalent Inhibitors Targeting the Lysine Methyltransferases G9a/GLP

Journal of Medicinal Chemistry
2023-06-02 | Journal article
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Contributors: Zongbo Feng; Chunju Yang; Yi Zhang; Huaxuan Li; Wei Fang; Junhua Wang; Yichu Nie; Changyun Wang; Zhiqing Liu; Zhimin Jiang et al.
Source: Self-asserted source
Junjian Wang

The binding mode of orphan glycyl-tRNA synthetase with tRNA supports the synthetase classification and reveals large domain movements

Science Advances
2023-02-10 | Journal article
Contributors: Lu Han; Zhiteng Luo; Yingchen Ju; Bingyi Chen; Taotao Zou; Junjian Wang; Jun Xu; Qiong Gu; Xiang-Lei Yang; Paul Schimmel et al.
Source: check_circle
Crossref

Discovery of Highly Potent Daphnane Diterpenoids Uncovers Importin-β1 as a Druggable Vulnerability in Castration-Resistant Prostate Cancer.

Journal of the American Chemical Society
2022-09-14 | Journal article
Contributors: Junjian Wang
Source: Self-asserted source
Junjian Wang

Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop via NRF2 in cancer therapeutic resistance

Acta Pharmaceutica Sinica B
2022-04 | Journal article
Part of ISSN: 2211-3835
Contributors: Junjian Wang
Source: Self-asserted source
Junjian Wang

The novel indomethacin derivative CZ-212-3 exerts antitumor effects on castration-resistant prostate cancer by degrading androgen receptor and its variants.

Acta pharmacologica Sinica
2022-04 | Journal article
Contributors: Junjian Wang
Source: Self-asserted source
Junjian Wang

Inhibition of STAT3-ferroptosis negative regulatory axis suppresses tumor growth and alleviates chemoresistance in gastric cancer.

Redox biology
2022-04-21 | Journal article
Source: Self-asserted source
Junjian Wang

Therapeutic targeting RORγ with natural product N-hydroxyapiosporamide for small cell lung cancer by reprogramming neuroendocrine fate.

Pharmacological research
2022-03-06 | Journal article
Source: Self-asserted source
Junjian Wang

Kynurenine-3-monooxygenase (KMO) broadly inhibits viral infections via triggering NMDAR/Ca2+ influx and CaMKII/ IRF3-mediated IFN-β production.

PLoS pathogens
2022-03-02 | Journal article
Source: Self-asserted source
Junjian Wang

Targeting autophagy peptidase ATG4B with a novel natural product inhibitor Azalomycin F4a for advanced gastric cancer

Cell Death & Disease
2022-02 | Journal article
Part of ISSN: 2041-4889
Source: Self-asserted source
Junjian Wang

Gold(<scp>i</scp>)-catalyzed redox transformation of <i>o</i>-nitroalkynes with indoles for the synthesis of 2,3′-biindole derivatives

Organic Chemistry Frontiers
2021 | Journal article
Part of ISSN: 2052-4129
Contributors: Su Zhou; Qianqian Liu; Ming Bao; Jie Huang; Junjian Wang; Wenhao Hu; Xinfang Xu
Source: Self-asserted source
Junjian Wang

Ilicicolin A Exerts Antitumor Effect in Castration-Resistant Prostate Cancer Via Suppressing EZH2 Signaling Pathway

Frontiers in Pharmacology
2021-10-27 | Journal article
Part of ISSN: 1663-9812
Source: Self-asserted source
Junjian Wang

Exploring Marine-Derived Ascochlorins as Novel Human Dihydroorotate Dehydrogenase Inhibitors for Treatment of Triple-Negative Breast Cancer

Journal of Medicinal Chemistry
2021-09-13 | Journal article
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Source: Self-asserted source
Junjian Wang

The m6A demethylase FTO promotes the osteogenesis of mesenchymal stem cells by downregulating PPARG

Acta Pharmacologica Sinica
2021-08-30 | Journal article
Part of ISSN: 1671-4083
Part of ISSN: 1745-7254
Source: Self-asserted source
Junjian Wang

Antitumor Effects of 3‐bromoascochlorin on Small Cell Lung Cancer via Inhibiting MAPK Pathway

Cell Biology International
2021-07-21 | Journal article
Part of ISSN: 1065-6995
Part of ISSN: 1095-8355
Source: Self-asserted source
Junjian Wang

Cyclopentenone-Containing Tetrahydroquinoline and Geldanamycin Alkaloids from <i>Streptomyces malaysiensis</i> as Potential Anti-Androgens against Prostate Cancer Cells.

Journal of natural products
2021-07-06 | Journal article
Source: Self-asserted source
Junjian Wang

Serum exosomes accelerate diabetic wound healing by promoting angiogenesis and ECM formation.

Cell biology international
2021-05-14 | Journal article
Source: Self-asserted source
Junjian Wang
grade
Preferred source (of 2)‎

Sorting nexin 3 induces heart failure via promoting retromer-dependent nuclear trafficking of STAT3.

Cell death and differentiation
2021-05-04 | Journal article
Source: Self-asserted source
Junjian Wang

Targeting Feedforward Loops Formed by Nuclear Receptor RORγ and Kinase PBK in mCRPC with Hyperactive AR Signaling.

Cancers
2021-04-01 | Journal article
Source: Self-asserted source
Junjian Wang
grade
Preferred source (of 3)‎

Targeting castration-resistant prostate cancer with a novel RORγ antagonist elaiophylin

Acta Pharmaceutica Sinica B
2020-12 | Journal article
Part of ISSN: 2211-3835
Source: Self-asserted source
Junjian Wang

The poly(ADP-ribosyl)ation of BRD4 mediated by PARP1 promoted pathological cardiac hypertrophy.

Acta pharmaceutica Sinica. B
2020-12-14 | Journal article
Source: Self-asserted source
Junjian Wang
grade
Preferred source (of 2)‎

Histone Demethylase JMJD3 Mediated Doxorubicin-Induced Cardiomyopathy by Suppressing SESN2 Expression.

Frontiers in cell and developmental biology
2020-09-29 | Journal article
Source: Self-asserted source
Junjian Wang

Prostacyclin facilitates vascular smooth muscle cell phenotypic transformation via activating TP receptors when IP receptors are deficient.

Acta physiologica (Oxford, England)
2020-09-04 | Journal article
Source: Self-asserted source
Junjian Wang

Histone H4R3 symmetric di-methylation by Prmt5 protects against cardiac hypertrophy via regulation of Filip1L/β-catenin.

Pharmacological research
2020-07-31 | Journal article
Source: Self-asserted source
Junjian Wang

Cytotoxic benzopyranone and xanthone derivatives from a coral symbiotic fungus Cladosporium halotolerans GXIMD 02502.

Natural product research
2020-07-27 | Journal article
Source: Self-asserted source
Junjian Wang

TRIB3-EGFR interaction promotes lung cancer progression and defines a therapeutic target.

Nature communications
2020-07-21 | Journal article
Source: Self-asserted source
Junjian Wang

Orphan nuclear receptor RORγ confers doxorubicin resistance in prostate cancer.

Cell biology international
2020-07-07 | Journal article
Source: Self-asserted source
Junjian Wang

Arctiin abrogates osteoclastogenesis and bone resorption via suppressing RANKL-induced ROS and NFATc1 activation.

Pharmacological research
2020-05-23 | Journal article
Source: Self-asserted source
Junjian Wang

Antioxidant CPA-type indole alkaloids produced from the deep-sea derived fungus Aspergillus sp. SCSIO 41024.

Natural product research
2020-04-07 | Journal article
Source: Self-asserted source
Junjian Wang

sFRP1 protects H9c2 cardiac myoblasts from doxorubicin-induced apoptosis by inhibiting the Wnt/PCP-JNK pathway.

Acta pharmacologica Sinica
2020-04-01 | Journal article
Source: Self-asserted source
Junjian Wang

S-adenosylhomocysteine (AdoHcy)-dependent methyltransferase inhibitor DZNep overcomes breast cancer tamoxifen resistance via induction of NSD2 degradation and suppression of NSD2-driven redox homeostasis.

Chemico-biological interactions
2020-01-28 | Journal article
Source: Self-asserted source
Junjian Wang

Targeting bromodomain protein ANCCA/ATAD2 enhances the efficacy of DNA‑damaging chemotherapy agents and radiation.

Oncology reports
2019-11-27 | Journal article
Source: Self-asserted source
Junjian Wang

RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype.

Nature communications
2019-10-11 | Journal article
Source: Self-asserted source
Junjian Wang
Items per page:
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