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Works (26)

Reversible covalent c-Jun N-terminal kinase inhibitors targeting a specific cysteine by precision-guided Michael-acceptor warheads

Nature Communications
2024-10-04 | Journal article
Contributors: Dániel Bálint; Ádám Levente Póti; Anita Alexa; Péter Sok; Krisztián Albert; Lili Torda; Dóra Földesi-Nagy; Dániel Csókás; Gábor Turczel; Tímea Imre et al.
Source: check_circle
Crossref

Targeting a key protein-protein interaction surface on mitogen-activated protein kinases by a precision-guided warhead scaffold

Nature Communications
2024-10-04 | Journal article
Contributors: Ádám Levente Póti; Dániel Bálint; Anita Alexa; Péter Sok; Kristóf Ozsváth; Krisztián Albert; Gábor Turczel; Sarolt Magyari; Orsolya Ember; Kinga Papp et al.
Source: check_circle
Crossref

Phosphorylation-Assisted Luciferase Complementation Assay Designed to Monitor Kinase Activity and Kinase-Domain-Mediated Protein–Protein Binding

International Journal of Molecular Sciences
2023-10 | Journal article | Author
Contributors: Ádám L. Póti; Laura Dénes; Kinga Papp; Csaba Bató; Zoltan Banoczi; Attila Remenyi; Anita Alexa
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Multidisciplinary Digital Publishing Institute
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Preferred source (of 2)‎

A non-catalytic herpesviral protein reconfigures ERK-RSK signaling by targeting kinase docking systems in the host

Nature Communications
2022-01-25 | Journal article
Contributors: Anita Alexa; Péter Sok; Fridolin Gross; Krisztián Albert; Evan Kobori; Ádám L. Póti; Gergő Gógl; Isabel Bento; Ersheng Kuang; Susan S. Taylor et al.
Source: check_circle
Crossref

Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38

Nature Communications
2020 | Journal article
EID:

2-s2.0-85095939643

Part of ISSN: 20411723
Contributors: Kirsch, K.; Zeke, A.; Tőke, O.; Sok, P.; Sethi, A.; Sebő, A.; Kumar, G.S.; Egri, P.; Póti, Á.L.; Gooley, P. et al.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier

MAP Kinase-Mediated Activation of RSK1 and MK2 Substrate Kinases

Structure
2020 | Journal article
EID:

2-s2.0-85088365436

Part of ISSN: 18784186 09692126
Contributors: Sok, P.; Gógl, G.; Kumar, G.S.; Alexa, A.; Singh, N.; Kirsch, K.; Sebő, A.; Drahos, L.; Gáspári, Z.; Peti, W. et al.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier

Theileria highjacks JNK2 into a complex with the macroschizont GPI (GlycosylPhosphatidylInositol)-anchored surface protein p104

Cellular Microbiology
2019 | Journal article
EID:

2-s2.0-85057759172

Part of ISSN: 14625822 14625814
Contributors: Latré De Laté, P.; Haidar, M.; Ansari, H.; Tajeri, S.; Szarka, E.; Alexa, A.; Woods, K.; Reményi, A.; Pain, A.; Langsley, G.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier

Dynamic control of RSK complexes by phosphoswitch-based regulation

FEBS Journal
2018 | Journal article
EID:

2-s2.0-85034227797

Part of ISSN: 17424658 1742464X
Contributors: Gógl, G.; Biri-Kovács, B.; Póti, Á.L.; Vadászi, H.; Szeder, B.; Bodor, A.; Schlosser, G.; Ács, A.; Turiák, L.; Buday, L. et al.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier

Tracking down protein-protein interactions: Via a FRET-system using site-specific thiol-labeling

Organic and Biomolecular Chemistry
2018 | Journal article
EID:

2-s2.0-85051524143

Part of ISSN: 14770520
Contributors: Söveges, B.; Imre, T.; Póti, A.L.; Sok, P.; Kele, Z.; Alexa, A.; Kele, P.; Németh, K.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier

Structural basis of ribosomal S6 kinase 1 (RSK1) inhibition by S100B protein: Modulation of the extracellular signal-regulated kinase (ERK) signaling cascade in a calcium-dependent way

Journal of Biological Chemistry
2016 | Journal article
EID:

2-s2.0-84952946332

Part of ISSN: 1083351X 00219258
Contributors: Gógl, G.; Alexa, A.; Kiss, B.; Katona, G.; Kovács, M.; Bodor, A.; Reményi, A.; Nyitray, L.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier

Structural assembly of the signaling competent ERK2-RSK1 heterodimeric protein kinase complex

Proceedings of the National Academy of Sciences of the United States of America
2015 | Journal article
EID:

2-s2.0-84924363700

Part of ISSN: 10916490 00278424
Contributors: Alexa, A.; Gógl, G.; Glatz, G.; Garai, A.; Zeke, A.; Varga, J.; Dudás, E.; Jeszenoi, N.; Bodor, A.; Hetényi, C. et al.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier

Systematic discovery of linear binding motifs targeting an ancient protein interaction surface on MAP kinases

Molecular Systems Biology
2015 | Journal article
EID:

2-s2.0-84948676335

Part of ISSN: 17444292
Contributors: Zeke, A.; Bastys, T.; Alexa, A.; Garai, Á.; Mészáros, B.; Kirsch, K.; Dosztányi, Z.; Kalinina, O.V.; Reményi, A.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier

Structural mechanism for the specific assembly and activation of the extracellular signal regulated kinase 5 (ERK5) module

Journal of Biological Chemistry
2013 | Journal article
EID:

2-s2.0-84875409408

Part of ISSN: 00219258 1083351X
Contributors: Glatz, G.; Gógl, G.; Alexa, A.; Reményi, A.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier

The NM23-H1/H2 homolog NDK-1 is required for full activation of Ras signaling in C. elegans

Development (Cambridge)
2013 | Journal article
EID:

2-s2.0-84880931711

Part of ISSN: 09501991 14779129
Contributors: Masoudi, N.; Fancsalszky, L.; Pourkarimi, E.; Vellai, T.; Alexa, A.; Reményi, A.; Gartner, A.; Mehta, A.; Takács-Vellai, K.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier

Specificity of linear motifs that bind to a common mitogen-activated protein kinase docking groove

Science Signaling
2012 | Journal article
EID:

2-s2.0-84867496035

Part of ISSN: 19450877 19379145
Contributors: Garai, Á.; Zeke, A.; Gógl, G.; Töro, I.; Fördos, F.; Blankenburg, H.; Bárkai, T.; Varga, J.; Alexa, A.; Emig, D. et al.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier

Protein disorder prevails under crowded conditions

Biochemistry
2011 | Journal article
EID:

2-s2.0-79959807835

Part of ISSN: 00062960 15204995
Contributors: Szasz, C.; Alexa, A.; Toth, K.; Rakacs, M.; Langowski, J.; Tompa, P.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier

Scaffolds are 'active' regulators of signaling modules

FEBS Journal
2010 | Journal article
EID:

2-s2.0-79952111440

Part of ISSN: 1742464X 17424658
Contributors: Alexa, A.; Varga, J.; Reményi, A.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier

Identifying calpain substrates in intact S2 cells of Drosophila

Archives of Biochemistry and Biophysics
2009 | Journal article
EID:

2-s2.0-58049215325

Part of ISSN: 00039861 10960384
Contributors: Bozoky, Z.; Alexa, A.; Dancsok, J.; Gogl, G.; Klement, E.; Medzihradszky, K.F.; Friedrich, P.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier

Regulation of calpain B from Drosophila melanogaster by phosphorylation

FEBS Journal
2009 | Journal article
EID:

2-s2.0-68849098806

Part of ISSN: 1742464X 17424658
Contributors: Kovács, L.; Alexa, A.; Klement, E.; Kókai, E.; Tantos, A.; Gógl, G.; Sperka, T.; Medzihradszky, K.F.; Tözsér, J.; Dombrádi, V. et al.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier

Novel cell-penetrating calpain substrate

Bioconjugate Chemistry
2008 | Journal article
EID:

2-s2.0-47749100056

Part of ISSN: 10431802
Contributors: Bánóczi, Z.; Alexa, A.; Farkas, A.; Friedrich, P.; Hudecz, F.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier

Multiple interactions of the 'transducer' govern its function in calpain activation by Ca<sup>2+</sup>

Biochemical Journal
2005 | Journal article
EID:

2-s2.0-21744441338

Part of ISSN: 02646021
Contributors: Bozóky, Z.; Alexa, A.; Tompa, P.; Friedrich, P.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier

Contribution of Distinct Structural Elements to Activation of Calpain by Ca<sup>2+</sup> Ions

Journal of Biological Chemistry
2004 | Journal article
EID:

2-s2.0-2442576938

Part of ISSN: 00219258
Contributors: Alexa, A.; Bozóky, Z.; Farkas, A.; Tompa, P.; Friedrich, P.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier

The phosphorylation state of threonine-220, a uniquely phosphatase-sensitive protein kinase a site in microtubule-associated protein MAP2c, regulates microtubule binding and stability

Biochemistry
2002 | Journal article
EID:

2-s2.0-0037108084

Part of ISSN: 00062960
Contributors: Alexa, A.; Schmidt, G.; Tompa, P.; Ogueta, S.; Vázquez, J.; Kulcsár, P.; Kovács, J.; Dombrádi, V.; Friedrich, P.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier

Autolysis parallels activation of μ-calpain

Biochemical Journal
1996 | Journal article
EID:

2-s2.0-0029746476

Part of ISSN: 02646021
Contributors: Baki, A.; Tompa, P.; Alexa, A.; Molnar, O.; Friedrich, P.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier

Mutual protection of microtubule-associated protein 2 (MAP2) and cyclic AMP-dependent protein kinase II against μ-calpain

Journal of Neuroscience Research
1996 | Journal article
EID:

2-s2.0-0029991680

Part of ISSN: 03604012
Contributors: Alexa, A.; Tompa, P.; Baki, A.; Vereb, G.; Friedrich, P.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier

An ultrasensitive, continuous fluorometric assay for calpain activity

Analytical Biochemistry
1995 | Journal article
EID:

2-s2.0-0029053012

Part of ISSN: 10960309 00032697
Contributors: Tompa, P.; Schád, É.; Baki, A.; Alexa, A.; Batke, J.; Friedrich, P.
Source: Self-asserted source
Anita Alexa via Scopus - Elsevier