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Persistence of an Infectious Form of SARS-CoV-2 After Protease Inhibitor Treatment of Permissive Cells In Vitro

The Journal of Infectious Diseases
2025-02-04 | Journal article
Contributors: Manoj S Nair; Maria I Luck; Yaoxing Huang; Yosef Sabo; David D Ho
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Crossref

Developing inhibitory peptides against SARS-CoV-2 envelope protein

PLOS Biology
2024-03-14 | Journal article
Contributors: Ramsey Bekdash; Frank Kirchhoff; Kazushige Yoshida; Manoj S. Nair; Lauren Qiu; Johnathan Ahdout; Hsiang-Yi Tsai; Kunihiro Uryu; Rajesh K. Soni; Yaoxing Huang et al.
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Crossref

Antibodies that neutralize all current SARS-CoV-2 variants of concern by conformational locking

bioRxiv
2023 | Other
EID:

2-s2.0-85160848279

Part of ISSN: 26928205
Contributors: Liu, L.; Casner, R.G.; Guo, Y.; Wang, Q.; Iketani, S.; Chan, J.F.-W.; Yu, J.; Dadonaite, B.; Nair, M.S.; Mohri, H. et al.
Source: Self-asserted source
Manoj nair via Scopus - Elsevier

Changes in serum-neutralizing antibody potency and breadth post-SARS-CoV-2 mRNA vaccine boost

IScience
2023 | Journal article
Contributors: Nair, Manoj S.; Ribeiro, Ruy M.; Wang, Maple; Bowen, Anthony D.; Liu, Lihong; Guo, Yicheng; Chang, Jennifer Y.; Wang, Pengfei; Sheng, Zizhang; Sobieszczyk, Magdalena E. et al.
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Antigenicity and receptor affinity of SARS-CoV-2 BA.2.86 spike

Nature
2023-12-21 | Journal article
Contributors: Qian Wang; Yicheng Guo; Liyuan Liu; Logan T. Schwanz; Zhiteng Li; Manoj S. Nair; Jerren Ho; Richard M. Zhang; Sho Iketani; Jian Yu et al.
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Crossref

Persistence of an infectious form of SARS-CoV-2 post protease inhibitor treatment of permissive cells in vitro

2023-12-21 | Preprint
Contributors: Manoj S. Nair; Maria I. Luck; Yaoxing Huang; Yosef Sabo; David D. Ho
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Crossref

An immunostimulatory glycolipid that blocks SARS-CoV-2, RSV, and influenza infections in vivo

Nature Communications
2023-07-05 | Journal article
Contributors: Moriya Tsuji; Manoj S. Nair; Kazuya Masuda; Candace Castagna; Zhenlu Chong; Tamarand L. Darling; Kuljeet Seehra; Youngmin Hwang; Ágata Lopes Ribeiro; Geovane Marques Ferreira et al.
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SARS-CoV-2 omicron variants are susceptible in vitro to Artemisia annua hot water extracts

Journal of Ethnopharmacology
2023-05 | Journal article
Contributors: M.S. Nair; Y. Huang; M. Wang; P.J. Weathers
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A multi-specific, multi-affinity antibody platform neutralizes sarbecoviruses and confers protection against SARS-CoV-2 in vivo

Science Translational Medicine
2023-05-24 | Journal article
Contributors: Clare Burn Aschner; Krithika Muthuraman; Iga Kucharska; Hong Cui; Katherine Prieto; Manoj S. Nair; Maple Wang; Yaoxing Huang; Natasha Christie-Holmes; Betty Poon et al.
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An Immunostimulatory Glycolipid That Blocks SARS-CoV-2, RSV, and Influenza Infections In Vivo

2023-03-08 | Preprint
Contributors: David Ho; Moriya Tsuji; Manoj Nair; Kazuya Masuda; Candace Castagna; Zhenlu Chong; Tamarand Darling; Kuljeet Seehra; Ágata Ribeiro; Geovane Ferreira et al.
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A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates

Science Translational Medicine
2022 | Journal article
EID:

2-s2.0-85124803256

Part of ISSN: 19466242 19466234
Contributors: Joyce, M.G.; King, H.A.D.; Elakhal-Naouar, I.; Ahmed, A.; Peachman, K.K.; Cincotta, C.M.; Subra, C.; Chen, R.E.; Thomas, P.V.; Chen, W.-H. et al.
Source: Self-asserted source
Manoj nair via Scopus - Elsevier

Antibody evasion by SARS-CoV-2 Omicron subvariants BA.2.12.1, BA.4, and BA.5

bioRxiv
2022 | Other
EID:

2-s2.0-85133470187

Part of ISSN: 26928205
Contributors: Wang, Q.; Guo, Y.; Iketani, S.; Nair, M.S.; Li, Z.; Mohri, H.; Wang, M.; Yu, J.; Bowen, A.D.; Chang, J.Y. et al.
Source: Self-asserted source
Manoj nair via Scopus - Elsevier

Artemisia annua L. hot-water extracts show potent activity in vitro against Covid-19 variants including delta

Journal of Ethnopharmacology
2022 | Journal article
EID:

2-s2.0-85118504378

Part of ISSN: 18727573 03788741
Contributors: Nair, M.S.; Huang, Y.; Fidock, D.A.; Towler, M.J.; Weathers, P.J.
Source: Self-asserted source
Manoj nair via Scopus - Elsevier

Changes in Serum Neutralizing Antibody Potency and Breadth Post SARS-CoV-2 mRNA Vaccine Boost

SSRN
2022 | Other
EID:

2-s2.0-85145491200

Part of ISSN: 15565068
Contributors: Nair, M.S.; Ribeiro, R.M.; Wang, M.; Bowen, A.D.; Liu, L.; Guo, Y.; Chang, J.Y.; Wang, P.; Sheng, Z.; Sobieszczyk, M.E. et al.
Source: Self-asserted source
Manoj nair via Scopus - Elsevier

Changes in Serum Neutralizing Antibody Potency and Breadth Post SARS-CoV-2 mRNA Vaccine Boost

SSRN Electronic Journal
2022 | Journal article
Part of ISSN: 1556-5068
Contributors: Manoj S. Nair; Ruy M. Ribeiro; Maple Wang; Anthony Bowen; Lihong Liu; Yicheng Guo; Jennifer Y. Chang; Pengfei Wang; Zizhang Sheng; Magdalena Sobieszczyk et al.
Source: Self-asserted source
Manoj nair

Defining the risk of SARS-CoV-2 variants on immune protection

Nature
2022 | Journal article
EID:

2-s2.0-85129706085

Part of ISSN: 14764687 00280836
Contributors: DeGrace, M.M.; Ghedin, E.; Frieman, M.B.; Krammer, F.; Grifoni, A.; Alisoltani, A.; Alter, G.; Amara, R.R.; Baric, R.S.; Barouch, D.H. et al.
Source: Self-asserted source
Manoj nair via Scopus - Elsevier

Quantifying the impact of immune history and variant on SARS-CoV-2 viral kinetics and infection rebound: a retrospective cohort study

medRxiv
2022 | Other
EID:

2-s2.0-85139374901

Contributors: Hay, J.A.; Kissler, S.M.; Fauver, J.R.; Mack, C.; Tai, C.G.; Samant, R.M.; Connolly, S.; Anderson, D.J.; Khullar, G.; MacKay, M. et al.
Source: Self-asserted source
Manoj nair via Scopus - Elsevier

SARS-CoV-2 Omicron Variants Succumb In Vitro to Artemisia Annua Hot Water Extracts

SSRN
2022 | Other
EID:

2-s2.0-85142377207

Part of ISSN: 15565068
Contributors: Nair, M.S.; Huang, Y.; Weathers, P.J.
Source: Self-asserted source
Manoj nair via Scopus - Elsevier

SARS-CoV-2 Omicron Variants Succumb In Vitro to Artemisia Annua Hot Water Extracts

SSRN Electronic Journal
2022 | Journal article
Part of ISSN: 1556-5068
Contributors: Manoj nair; Manoj S. Nair; Yaoxing Huang; Pamela Weathers
Source: Self-asserted source
Manoj nair

A monoclonal antibody that neutralizes SARS-CoV-2 variants, SARS-CoV, and other sarbecoviruses

Emerging Microbes & Infections
2022-12-31 | Journal article
Contributors: Pengfei Wang; Ryan G. Casner; Manoj S. Nair; Jian Yu; Yicheng Guo; Maple Wang; Jasper F.-W. Chan; Gabriele Cerutti; Sho Iketani; Lihong Liu et al.
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Quantifying the impact of immune history and variant on SARS-CoV-2 viral kinetics and infection rebound: A retrospective cohort study

eLife
2022-11-16 | Journal article | Author
Part of ISSN: 2050-084X
Contributors: James A Hay; Stephan Kissler; Joseph R Fauver; Christina Mack; Caroline G Tai; Radhika M Samant; Sarah Connolly; Deverick J Anderson; Gaurav Khullar; Matthew MacKay et al.
Source: Self-asserted source
Manoj nair
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Antibody avidity and multi-specificity combined to confer protection against SARS-CoV-2 and resilience against viral escape

[]
2022-10-24 | Preprint
Contributors: Manoj nair; Clare Burn Aschner; Krithika Muthuraman; Iga Kucharska; Hong Cui; Katherine Prieto; Manoj S. Nair; Maple Wang; Yaoxing Huang; Natasha Christie-Holmes et al.
Source: Self-asserted source
Manoj nair
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Antibody evasion by SARS-CoV-2 Omicron subvariants BA.2.12.1, BA.4 and BA.5

Nature
2022-08-18 | Journal article
Contributors: Qian Wang; Yicheng Guo; Sho Iketani; Manoj S. Nair; Zhiteng Li; Hiroshi Mohri; Maple Wang; Jian Yu; Anthony D. Bowen; Jennifer Y. Chang et al.
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An Immunostimulatory Glycolipid That Blocks SARS-CoV-2, RSV, and Influenza Infections In Vivo

2022-07-14 | Preprint
Contributors: David Ho; Moriya Tsuji; Manoj Nair; Kazuya Masuda; Candace Castagna; Zhenlu Chong; Tamarand Darling; Kuljeet Seehra; Ágata Ribeiro; Geovane Ferreira et al.
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Crossref

An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses

Science Translational Medicine
2022-05-25 | Journal article
Contributors: Lihong Liu; Sho Iketani; Yicheng Guo; Eswar R. Reddem; Ryan G. Casner; Manoj S. Nair; Jian Yu; Jasper F.-W. Chan; Maple Wang; Gabriele Cerutti et al.
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Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19

Nature Communications
2022-04-07 | Journal article
Contributors: Hengrui Liu; Sho Iketani; Arie Zask; Nisha Khanizeman; Eva Bednarova; Farhad Forouhar; Brandon Fowler; Seo Jung Hong; Hiroshi Mohri; Manoj S. Nair et al.
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Defining the risk of SARS-CoV-2 variants on immune protection.

Apollo - University of Cambridge Repository
2022-03-31 | Journal article
Contributors: Marciela M DeGrace; Elodie Ghedin; Matthew Frieman; Florian Krammer; Alba; Arghavan Alisoltani; Galit Alter; Rama Rao Amara; Ralph Baric; Dan H. Barouch et al.
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DataCite

Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2

Nature
2022-02-24 | Journal article
Contributors: Lihong Liu; Sho Iketani; Yicheng Guo; Jasper F.-W. Chan; Maple Wang; Liyuan Liu; Yang Luo; Hin Chu; Yiming Huang; Manoj S. Nair et al.
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A monoclonal antibody that neutralizes SARS-CoV-2 variants, SARS-CoV, and other sarbecoviruses

bioRxiv
2021 | Other
EID:

2-s2.0-85119849117

Part of ISSN: 26928205
Contributors: Wang, P.; Casner, R.G.; Nair, M.S.; Yu, J.; Guo, Y.; Wang, M.; Chan, J.F.-W.; Cerutti, G.; Iketani, S.; Liu, L. et al.
Source: Self-asserted source
Manoj nair via Scopus - Elsevier

A third COVID-19 vaccine shot markedly boosts neutralizing antibody potency and breadth

medRxiv
2021 | Other
EID:

2-s2.0-85115831325

Contributors: Iketani, S.; Liu, L.; Nair, M.S.; Mohri, H.; Wang, M.; Huang, Y.; Ho, D.D.
Source: Self-asserted source
Manoj nair via Scopus - Elsevier

Artemisia annua L. extracts prevent in vitro replication of SARS-CoV-2

bioRxiv
2021 | Journal article
Source: Self-asserted source
Manoj nair
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Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques

bioRxiv
2021 | Other
EID:

2-s2.0-85106393089

Part of ISSN: 26928205
Contributors: King, H.A.D.; Joyce, M.G.; Naouar, I.E.; Ahmed, A.; Cincotta, C.M.; Subra, C.; Peachman, K.K.; Hack, H.H.; Chen, R.E.; Thomas, P.V. et al.
Source: Self-asserted source
Manoj nair via Scopus - Elsevier

Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques

Proceedings of the National Academy of Sciences
2021 | Journal article
Part of ISSN: 0027-8424
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Manoj nair
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Efficacy of a Broadly Neutralizing SARS-CoV-2 Ferritin Nanoparticle Vaccine in Nonhuman Primates

bioRxiv
2021 | Journal article
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Manoj nair
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Emergence and expansion of the SARS-CoV-2 variant B.1.526 identified in New York

medRxiv
2021 | Other
EID:

2-s2.0-85116172155

Contributors: Annavajhala, M.K.; Mohri, H.; Wang, P.; Nair, M.; Zucker, J.E.; Sheng, Z.; Gomez-Simmonds, A.; Kelley, A.L.; Tagliavia, M.; Huang, Y. et al.
Source: Self-asserted source
Manoj nair via Scopus - Elsevier

Increased resistance of SARS-CoV-2 variant P.1 to antibody neutralization

Cell Host and Microbe
2021 | Journal article
EID:

2-s2.0-85105476536

Part of ISSN: 19346069 19313128
Contributors: Wang, P.; Casner, R.G.; Nair, M.S.; Wang, M.; Yu, J.; Cerutti, G.; Liu, L.; Kwong, P.D.; Huang, Y.; Shapiro, L. et al.
Source: Self-asserted source
Manoj nair via Scopus - Elsevier

Increased Resistance of SARS-CoV-2 Variant P.1 to Antibody Neutralization

BioRxiv
2021 | Journal article
Contributors: Wang, P.; Casner, R. G.; Nair, M. S.; Wang, M.; Yu, J.; Cerutti, G.; Liu, L.; Kwong, P. D.; Huang, Y.; Shapiro, L. et al.
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Increased Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 to Antibody Neutralization

bioRxiv
2021 | Journal article
Source: Self-asserted source
Manoj nair
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Isolation and comparative analysis of antibodies that broadly neutralize sarbecoviruses

bioRxiv
2021 | Other
EID:

2-s2.0-85123696131

Part of ISSN: 26928205
Contributors: Liu, L.; Iketani, S.; Guo, Y.; Casner, R.G.; Reddem, E.R.; Nair, M.S.; Yu, J.; Chan, J.F.-W.; Wang, M.; Cerutti, G. et al.
Source: Self-asserted source
Manoj nair via Scopus - Elsevier

Paired heavy and light chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses

bioRxiv
2021 | Other
EID:

2-s2.0-85100810706

Part of ISSN: 26928205
Contributors: Banach, B.B.; Cerutti, G.; Fahad, A.S.; Shen, C.-H.; de Souza, M.O.; Katsamba, P.S.; Tsybovsky, Y.; Wang, P.; Nair, M.S.; Huang, Y. et al.
Source: Self-asserted source
Manoj nair via Scopus - Elsevier

Paired heavy- and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses

Cell Reports
2021 | Journal article
EID:

2-s2.0-85115986353

Part of ISSN: 22111247
Contributors: Banach, B.B.; Cerutti, G.; Fahad, A.S.; Shen, C.-H.; Oliveira De Souza, M.; Katsamba, P.S.; Tsybovsky, Y.; Wang, P.; Nair, M.S.; Huang, Y. et al.
Source: Self-asserted source
Manoj nair via Scopus - Elsevier

Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite

Cell Host and Microbe
2021 | Journal article
EID:

2-s2.0-85103480307

Part of ISSN: 19346069 19313128
Contributors: Cerutti, G.; Guo, Y.; Zhou, T.; Gorman, J.; Lee, M.; Rapp, M.; Reddem, E.R.; Yu, J.; Bahna, F.; Bimela, J. et al.
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Manoj nair via Scopus - Elsevier

Antibody screening at reduced pH enables preferential selection of potently neutralizing antibodies targeting SARS‐CoV‐2

AIChE Journal
2021-12 | Journal article
Contributors: Bharat Madan; Eswar R. Reddem; Pengfei Wang; Ryan G. Casner; Manoj S. Nair; Yaoxing Huang; Ahmed S. Fahad; Matheus Oliveira de Souza; Bailey B. Banach; Sheila N. López Acevedo et al.
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An airway organoid-based screen identifies a role for the HIF1α-glycolysis axis in SARS-CoV-2 infection

Cell Reports
2021-11 | Journal article
Contributors: Xiaohua Duan; Xuming Tang; Manoj S. Nair; Tuo Zhang; Yunping Qiu; Wei Zhang; Pengfei Wang; Yaoxing Huang; Jenny Xiang; Hui Wang et al.
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Functional differences among the spike glycoproteins of multiple emerging SARS-CoV-2 variants of concern

iScience
2021-11 | Journal article
Contributors: Qian Wang; Manoj S. Nair; Saumya Anang; Shijian Zhang; Hanh Nguyen; Yaoxing Huang; Lihong Liu; David D. Ho; Joseph G. Sodroski
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Neutralizing antibody 5-7 defines a distinct site of vulnerability in SARS-CoV-2 spike N-terminal domain

Cell Reports
2021-11 | Journal article
Contributors: Gabriele Cerutti; Yicheng Guo; Pengfei Wang; Manoj S. Nair; Maple Wang; Yaoxing Huang; Jian Yu; Lihong Liu; Phinikoula S. Katsamba; Fabiana Bahna et al.
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Emergence and expansion of SARS-CoV-2 B.1.526 after identification in New York

Nature
2021-09-30 | Journal article
Contributors: Medini K. Annavajhala; Hiroshi Mohri; Pengfei Wang; Manoj Nair; Jason E. Zucker; Zizhang Sheng; Angela Gomez-Simmonds; Anne L. Kelley; Maya Tagliavia; Yaoxing Huang et al.
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Artemisia annua hot-water extracts show potent activity in vitro against Covid-19 variants including delta

[]
2021-09-08 | Preprint
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Manoj nair
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Artemisia annua L. extracts inhibit the in vitro replication of SARS-CoV-2 and two of its variants

Journal of Ethnopharmacology
2021-06 | Journal article
Part of ISSN: 0378-8741
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Neutralizing antibody 5-7 defines a distinct site of vulnerability in SARS-CoV-2 spike N-terminal domain

2021-06-29 | Other
Contributors: Gabriele Cerutti; Yicheng Guo; Pengfei Wang; Manoj S. Nair; Yaoxing Huang; Jian Yu; Lihong Liu; Phinikoula S. Katsamba; Fabiana Bahna; Eswar R. Reddem et al.
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