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Employment (1)

Yale University School of Medicine: New Haven, CT, US

2016-07 to present | Associate Research Scientist (PET Center, Department of Radiology and Biomedical Imaging)
Employment
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Songye Li

Works (14)

Plasma Glial Fibrillary Acid Protein and Phosphorated Tau 181 Association with Presynaptic Density-Dependent Tau Pathology at 18F-SynVesT-1 Brain PET Imaging

Radiology
2024-11-01 | Journal article
DOI: 10.1148/radiol.233019
Contributors: Junhao Wu; Binyin Li; Jie Wang; Qi Huang; Xing Chen; Zhiwen You; Kun He; Qihao Guo; Songye Li; Yiyun Henry Huang et al.
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Evaluation of a First PET Tracer Suitable for Imaging the Sigma-2 Receptor in the Brain of Nonhuman Primates

Molecular Pharmaceutics
2024-01-01 | Journal article
DOI: 10.1021/acs.molpharmaceut.3c00750
Contributors: Santosh Reddy Alluri; MingQiang Zheng; Daniel Holden; Ying Zhang; Li Zhang; Zachary Felchner; Songye Li; Jim Ropchan; Richard Carson; Hongmei Jia et al.
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PET imaging of kappa opioid receptors and receptor expression quantified in neuron-derived extracellular vesicles in socially housed female and male cynomolgus macaques

Neuropsychopharmacology
2023-01 | Journal article
DOI: 10.1038/s41386-022-01444-9
Contributors: Bernard N. Johnson; Ashish Kumar; Yixin Su; Sangeeta Singh; Kiran Kumar Solingapuram Sai; Susan H. Nader; Songye Li; Beth A. Reboussin; Yiyun Huang; Gagan Deep et al.
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Crossref

Further Investigation of Synaptic Vesicle Protein 2A (SV2A) Ligands Designed for Positron Emission Tomography and Single-Photon Emission Computed Tomography Imaging: Synthesis and Structure–Activity Relationship of Substituted Pyridinylmethyl-4-(3,5-difluorophenyl)pyrrolidin-2-ones

ACS Omega
2021-10-26 | Journal article
DOI: 10.1021/acsomega.1c02433
Contributors: Richard Pracitto; Kyle C. Wilcox; Marcel Lindemann; Jie Tong; Chao Zheng; Songye Li; Sjoerd J. Finnema; Yiyun Huang; Zhengxin Cai
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Crossref

Assessment of test-retest reproducibility of [18F]SynVesT-1, a novel radiotracer for PET imaging of synaptic vesicle glycoprotein 2A

European Journal of Nuclear Medicine and Molecular Imaging
2021-05-08 | Journal article
DOI: 10.1007/s00259-020-05149-3
Contributors: Songye Li; Mika Naganawa; Richard Pracitto; Soheila Najafzadeh; Daniel Holden; Shannan Henry; David Matuskey; Paul R. Emery; Zhengxin Cai; Jim Ropchan et al.
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First-in-human evaluation of 18F-SynVesT-1, a novel radioligand for PET imaging of synaptic vesicle protein 2A

Journal of Nuclear Medicine
2020-08-28 | Journal article
DOI: 10.2967/jnumed.120.249144
Contributors: Mika Naganawa; Songye Li; Nabeel B Nabulsi; Shannan Henry; Ming-Qiang Zheng; Richard Pracitto; Zhengxin Cai; Hong Gao; Michael Kapinos; David Labaree et al.
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Crossref

Positron Emission Tomography Imaging Evaluation of a Novel 18F-Labeled Sigma-1 Receptor Radioligand in Cynomolgus Monkeys

ACS Chemical Neuroscience
2020-06-03 | Journal article
DOI: 10.1021/acschemneuro.0c00171
Contributors: Hongmei Jia; Zhengxin Cai; Daniel Holden; Yingfang He; Shu-fei Lin; Songye Li; Evan Baum; Anupama Shirali; Michael Kapinos; Hong Gao et al.
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Kinetic modeling and test-retest reproducibility of 11C-EKAP and 11C-FEKAP, novel agonist radiotracers for PET imaging of the kappa opioid receptor in humans

Journal of Nuclear Medicine
2020-03-13 | Journal article
DOI: 10.2967/jnumed.119.227694
Contributors: Mika Naganawa; Songye Li; Nabeel B Nabulsi; Shu-fei Lin; David Labaree; Jim Ropchan; Hong Gao; Michael Mei; Shannan Henry; David Matuskey et al.
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Crossref

Synthesis and Preclinical Evaluation of an 18F-Labeled Synaptic Vesicle Glycoprotein 2A PET Imaging Probe: [18F]SynVesT-2

ACS Chemical Neuroscience
2020-02-19 | Journal article
DOI: 10.1021/acschemneuro.9b00618
Contributors: Zhengxin Cai; Songye Li; Wenjie Zhang; Richard Pracitto; Xiaoai Wu; Evan Baum; Sjoerd J. Finnema; Daniel Holden; Takuya Toyonaga; Shu-fei Lin et al.
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Social status and demographic effects of the kappa opioid receptor: a PET imaging study with a novel agonist radiotracer in healthy volunteers

Neuropsychopharmacology
2019-09 | Journal article
DOI: 10.1038/s41386-019-0379-7
Contributors: David Matuskey; Mark Dias; Mika Naganawa; Brian Pittman; Shannan Henry; Songye Li; Hong Gao; Jim Ropchan; Nabeel Nabulsi; Richard E. Carson et al.
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Crossref

Synthesis and in vivo evaluation of [18F]UCB-J for PET imaging of synaptic vesicle glycoprotein 2A (SV2A)

European Journal of Nuclear Medicine and Molecular Imaging
2019-08 | Journal article
DOI: 10.1007/s00259-019-04357-w
Contributors: Songye Li; Zhengxin Cai; Wenjie Zhang; Daniel Holden; Shu-fei Lin; Sjoerd J. Finnema; Anupama Shirali; Jim Ropchan; Stephane Carre; Joel Mercier et al.
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A Novel 18F-Labeled Radioligand for Positron Emission Tomography Imaging of 11β-Hydroxysteroid Dehydrogenase (11β-HSD1): Synthesis and Preliminary Evaluation in Nonhuman Primates

ACS Chemical Neuroscience
2019-05-15 | Journal article
DOI: 10.1021/acschemneuro.8b00715
Contributors: Evan Baum; Wenjie Zhang; Songye Li; Zhengxin Cai; Daniel Holden; Yiyun Huang
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Crossref

Novel Kappa Opioid Receptor Agonist as Improved PET Radiotracer: Development and in Vivo Evaluation

Molecular Pharmaceutics
2019-04-01 | Journal article
DOI: 10.1021/acs.molpharmaceut.8b01209
Contributors: Songye Li; Ming-Qiang Zheng; Mika Naganawa; Hong Gao; Richard Pracitto; Anupama Shirali; Shu-fei Lin; Jo-Ku Teng; Jim Ropchan; Yiyun Huang
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Crossref

Synthesis and in Vivo Evaluation of a Novel PET Radiotracer for Imaging of Synaptic Vesicle Glycoprotein 2A (SV2A) in Nonhuman Primates

ACS Chemical Neuroscience
2019-03-20 | Journal article
DOI: 10.1021/acschemneuro.8b00526
Contributors: Songye Li; Zhengxin Cai; Xiaoai Wu; Daniel Holden; Richard Pracitto; Michael Kapinos; Hong Gao; David Labaree; Nabeel Nabulsi; Richard E. Carson et al.
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Peer review (5 reviews for 4 publications/grants)

Review activity for ACS chemical neuroscience. (1)
Review activity for EJNMMI research. (2)
Review activity for European journal of nuclear medicine and molecular imaging. (1)
Review activity for Nature communications (1)
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