Personal information

Emails & domains

Verified email domains

Websites & social links

Lab Website
Genome Institute Faculty Profile
GitHub GriffithLab
Personal/Professional Website

Other IDs

Scopus Author ID: 7102075315
ResearcherID: P-1285-2014

Keywords

Bioinformatics Cancer Informatics Programming Chemotherapy Analysis Next-Generation Sequencing RNA-Seq WGS Exome

Biography

Associate Professor, Department of Medicine, Washington University School of Medicine
Associate Professor, Department of Genetics, Washington University School of Medicine
Assistant Director, McDonnell Genome Institute, Washington University School of Medicine
Member, Siteman Cancer Center

My lab conducts research in medical genetics specializing in the application of molecular biology, informatics, and statistics to the study of cancer.

Cancer informatics - a combination of genomics, data analysis, and bioinformatics methods development with the ultimate goal of increasing our understanding of cancer biology and improving cancer treatment. I am one of a few scientists leading development of our clinical cancer sequencing and analysis pipeline, development of improved somatic event detection, evaluation of multiple tools and algorithms, and the application of these methods to several large scale next-generation sequencing projects involving: evolution of breast cancer under treatment, the genomic landscape of hepatocellular cancer, BRAF inhibitor resistance in colon cancer, clinical applications of next-generation sequencing in ALL, etc.

Activities

Collapse all

Employment (12)

Washington University in Saint Louis: Saint Louis, MO, US

2020-07-01 to present | Associate Professor (Medicine (Oncology))
Employment
Source: Self-asserted source
Malachi Griffith

Washington University in Saint Louis: Saint Louis, MO, US

2014-08-01 to present | Assistant Director (McDonnell Genome Institute)
Employment
Source: Self-asserted source
Malachi Griffith

Washington University in Saint Louis: Saint Louis, MO, US

2011-04-01 to present | Assistant Professor (Genetics)
Employment
Source: Self-asserted source
Malachi Griffith

Ontario Institute for Cancer Research: Toronto, ON, CA

2011-01-01 to present | Workshop instructor (Canadian Bioinformatics Workshops)
Employment
Source: Self-asserted source
Malachi Griffith

Cold Spring Harbor Laboratory: Cold Spring Harbor, NY, US

2011-01-01 to present | Workshop Instructor (Courses)
Employment
Source: Self-asserted source
Malachi Griffith

British Columbia Cancer Agency: Vancouver, BC, CA

2010-01-01 to 2011-02-01 | Postdoctoral Fellow (Genome Sciences Center)
Employment
Source: Self-asserted source
Malachi Griffith

University of British Columbia: Vancouver, BC, CA

2004-08-31 to 2009-12-01 | PhD Candidate, Teaching Assistant (Medical Genetics)
Employment
Source: Self-asserted source
Malachi Griffith

British Columbia Cancer Agency: Vancouver, BC, CA

2003-08-01 to 2004-08-01 | Computational Biologist (Genome Sciences Center)
Employment
Source: Self-asserted source
Malachi Griffith

University of Manitoba: Winnipeg, MB, CA

2000-05-01 to 2003-07-01 | Research Assistant / Research Technician 3 (Biochemistry and Medical Genetics)
Employment
Source: Self-asserted source
Malachi Griffith

University of Winnipeg: Winnipeg, MB, CA

2000-09-01 to 2003-05-01 | Laboratory Demonstrator (Biology)
Employment
Source: Self-asserted source
Malachi Griffith

University of Winnipeg: Winnipeg, MB, CA

2002-01-01 to 2003-01-01 | Web and Database Application Developer (Library Sciences)
Employment
Source: Self-asserted source
Malachi Griffith

Atomic Energy of Canada Limited: Pinawa, MB, CA

1996-07-01 to 1996-09-31 | Research Student (Electron Accelerator Division)
Employment
Source: Self-asserted source
Malachi Griffith

Education and qualifications (4)

University of British Columbia: Vancouver, BC, CA

2004-09-01 to 2009-05-01 | PhD (Medical Genetics)
Education
Source: Self-asserted source
Malachi Griffith

Simon Fraser University: Burnaby, BC, CA

2004-08-01 to 2005-05-30 | PhD (Bioinformatics)
Education
Source: Self-asserted source
Malachi Griffith

University of Winnipeg: Winnipeg, MB, CA

2002-09-01 to 2003-05-30 (Business Computing)
Education
Source: Self-asserted source
Malachi Griffith

University of Winnipeg: Winnipeg, MB, CA

1996-09-01 to 2002-05-01 | B.Sc. (Honors) (Biochemistry, Biology (double major))
Education
Source: Self-asserted source
Malachi Griffith

Funding (14)

Genomic and Functional Identification of Chemotherapy Resistance Mechanisms in Small Cell Lung Cancer

2018-09-01 to 2023-08-31 | Grant
National Cancer Institute (Rockville, US)
URL: https://app.dimensions.ai/details/grant/grant.7752428
GRANT_NUMBER: U01CA231844
Source: Self-asserted source
Malachi Griffith via DimensionsWizard

Integrated Analysis & Interpretation of Whole Genome Exome & Transcriptome Sequen

2017-05-01 to 2020-04-30 | Grant
National Human Genome Research Institute (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.6803671
GRANT_NUMBER: R00HG007940
Source: Self-asserted source
Malachi Griffith via DimensionsWizard

Towards True Precision Oncology: Validation of a Comprehensively Humanized, Autologous Mouse Model

2017-01-09 to 2019-12-31 | Grant
National Cancer Institute (Rockville, US)
URL: https://app.dimensions.ai/details/grant/grant.6541294
GRANT_NUMBER: R01CA204115
Source: Self-asserted source
Malachi Griffith via DimensionsWizard

DEVELOPMENT OF INFORMATICS RESOURCES FOR INTERPRETATION OF CLINICALLY ACTIONABLE VARIANTS IN CANCER

2016-07-20 to 2019-06-30 | Grant
National Cancer Institute (Rockville, US)
URL: https://app.dimensions.ai/details/grant/grant.5476310
GRANT_NUMBER: U01CA209936
Source: Self-asserted source
Malachi Griffith via DimensionsWizard

INTEGRATED ANALYSIS & INTERPRETATION OF WHOLE GENOME, EXOME & TRANSCRIPTOME SEQUENCE DATA IN CANCER

Source: Self-asserted source
Malachi Griffith via DimensionsWizard

INTEGRATED ANALYSIS & INTERPRETATION OF WHOLE GENOME, EXOME & TRANSCRIPTOME SEQUENCE DATA IN CANCER

2015-05-01 to 2017-04-30 | Grant
National Human Genome Research Institute (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.4055190
GRANT_NUMBER: K99HG007940
Source: Self-asserted source
Malachi Griffith via DimensionsWizard

The use of novel genomic approaches to identify and characterize genes associated with 5-FU resistance in colorectal cancer

Source: Self-asserted source
Malachi Griffith via DimensionsWizard

The use of novel genomic approaches to identify and characterize genes associated with 5-FU resistance in colorectal cancer

2008-07-01 to 2011-02-28 | Grant
Terry Fox Foundation (Burnaby, CA)
URL: https://app.dimensions.ai/details/grant/grant.7635645
GRANT_NUMBER:

61b7513ff5ef1d2dc0500675e94ce883
Source: Self-asserted source
Malachi Griffith via DimensionsWizard

A systematic characterization of alternative splicing in cancer progression

2007-04-01 to 2008-03-31 | Grant
Natural Sciences and Engineering Research Council of Canada (Ottawa, CA)
URL: https://grants.uberresearch.com/501100000038/371586/A-systematic-characterization-of-alternative-splicing-in-cancer-progression
GRANT_NUMBER: 371586
Source: Self-asserted source
Malachi Griffith via DimensionsWizard

Protein isoforms generated by alternative splicing: prevalence and relevance to models of cancer progression

2006-09-01 to 2009-08-31 | Grant
Michael Smith Foundation for Health Research (n/a, CA)
URL: https://grants.uberresearch.com/501100000245/10059/Protein-isoforms-generated-by-alternative-splicing-prevalence-and-relevance-to-models-of-cancer-progression
GRANT_NUMBER:

10059
Source: Self-asserted source
Malachi Griffith via DimensionsWizard

A systematic characterization of alternative splicing in cancer progression

2006-04-01 to 2007-03-31 | Grant
Natural Sciences and Engineering Research Council of Canada (Ottawa, CA)
URL: https://grants.uberresearch.com/501100000038/329153/A-systematic-characterization-of-alternative-splicing-in-cancer-progression
GRANT_NUMBER: 329153
Source: Self-asserted source
Malachi Griffith via DimensionsWizard

A systematic characterization of alternative splicing in cancer progression

2005-04-01 to 2006-03-31 | Grant
Natural Sciences and Engineering Research Council of Canada (Ottawa, CA)
URL: https://grants.uberresearch.com/501100000038/297937/A-systematic-characterization-of-alternative-splicing-in-cancer-progression
GRANT_NUMBER: 297937
Source: Self-asserted source
Malachi Griffith via DimensionsWizard

Identification of alternative splice variants and changes in patterns of alternative splicing involved in cancer by bioinformatic analysis and expression studies

Source: Self-asserted source
Malachi Griffith via DimensionsWizard

Identification of alternatively spliced transcripts and changes in patterns of alternative splicing associated with cancer

2004-04-01 to 2005-03-31 | Grant
Natural Sciences and Engineering Research Council of Canada (Ottawa, CA)
URL: https://grants.uberresearch.com/501100000038/274629/Identification-of-alternatively-spliced-transcripts-and-changes-in-patterns-of-alternative-splicing-associated-with-cancer
GRANT_NUMBER: 274629
Source: Self-asserted source
Malachi Griffith via DimensionsWizard

Works (50 of 69)

Items per page:
Page 1 of 2

Identifying Genetic Errors of Immunity due to Mosaicism

2025-03-24 | Other
DOI: 10.1084/jem.20241045
Contributors: Elizabeth Schmitz; Malachi Griffith; Obi Griffith; Megan Cooper
Source: check_circle
Crossref

DGIdb 5.0: Rebuilding the drug-gene interaction database for precision medicine and drug discovery platforms

2023-10-24 | Other
DOI: 10.1093/nar/gkad1040
Contributors: Malachi Griffith; Elaine R Mardis; Susanna Kiwala; Kelsy Cotto; Adam Coffman; Obi Griffith; Alex Wagner; James Stevenson; Kori Kuzma; Kathryn Stahl et al.
Source: check_circle
Crossref

Normalization of drug and therapeutic concepts with Thera-Py

JAMIA Open
2023-10-04 | Journal article
DOI: 10.1093/jamiaopen/ooad093
Contributors: Matthew Cannon; James Stevenson; Kori Kuzma; Susanna Kiwala; Jeremy L Warner; Obi L Griffith; Malachi Griffith; Alex H Wagner
Source: check_circle
Crossref

Donor-Derived Follicular Lymphoma After Kidney Transplantation: A Case Report

JCO Precision Oncology
2023-09 | Journal article
DOI: 10.1200/PO.23.00177
Contributors: Kartik Singhal; Marcus P. Watkins; Todd A. Fehniger; Malachi Griffith; Obi L. Griffith; Brad S. Kahl; David A. Russler-Germain
Source: check_circle
Crossref

Sex- and Mutation-Specific p53 Gain-of-Function Activity in Gliomagenesis

Cancer Research Communications
2021-12-15 | Journal article
DOI: 10.1158/2767-9764.CRC-21-0026
Contributors: Nathan C. Rockwell; Wei Yang; Nicole M. Warrington; Max V. Staller; Malachi Griffith; Obi L. Griffith; Christina A. Gurnett; Barak A. Cohen; Dustin Baldridge; Joshua B. Rubin
Source: check_circle
Crossref

The GA4GH Variation Representation Specification: A computational framework for variation representation and federated identification

Cell Genomics
2021-11 | Journal article
DOI: 10.1016/j.xgen.2021.100027
Contributors: Alex H. Wagner; Lawrence Babb; Gil Alterovitz; Michael Baudis; Matthew Brush; Daniel L. Cameron; Melissa Cline; Malachi Griffith; Obi L. Griffith; Sarah E. Hunt et al.
Source: check_circle
Crossref

p53 mutations exhibit sex specific gain-of-function activity in gliomagenesis

2021-06-11 | Other
DOI: 10.1101/2021.06.11.448124
Contributors: Nathan C Rockwell; Wei Yang; Nicole Warrington; Malachi Griffith; Obi L Griffith; Christina Gurnett; Barak Cohen; Dustin Baldridge; Joshua B Rubin
Source: check_circle
Crossref

Genetic Ancestry Correlations with Driver Mutations Suggest Complex Interactions between Somatic and Germline Variation in Cancer

Cancer Discovery
2021-03-01 | Journal article
DOI: 10.1158/2159-8290.CD-21-0092
Contributors: Felicia Gomez; Malachi Griffith; Obi L. Griffith
Source: check_circle
Crossref

The GA4GH Variation Representation Specification (VRS): a Computational Framework for the Precise Representation and Federated Identification of Molecular Variation

2021-01-17 | Preprint
DOI: 10.1101/2021.01.15.426843
Contributors: Alex H Wagner; Lawrence Babb; Gil Alterovitz; Michael Baudis; Matthew Brush; Daniel L Cameron; Melissa Cline; Malachi Griffith; Obi L Griffith; Sarah Hunt et al.
Source: check_circle
Crossref

Integration of the Drug–Gene Interaction Database (DGIdb 4.0) with open crowdsource efforts

Nucleic Acids Research
2021-01-08 | Journal article
DOI: 10.1093/nar/gkaa1084
Contributors: Sharon L Freshour; Susanna Kiwala; Kelsy C Cotto; Adam C Coffman; Joshua F McMichael; Jonathan J Song; Malachi Griffith; Obi L Griffith; Alex H Wagner
Source: check_circle
Crossref

Splicing factor SF3B1 promotes endometrial cancer progression via regulating KSR2 RNA maturation

Cell Death & Disease
2020-10-10 | Journal article
DOI: 10.1038/s41419-020-03055-y
Contributors: Pooja Popli; Megan M. Richters; Sangappa B. Chadchan; Tae Hoon Kim; Eric Tycksen; Obi Griffith; Premal H. Thaker; Malachi Griffith; Ramakrishna Kommagani
Source: check_circle
Crossref

Integration of the Drug-Gene Interaction Database (DGIdb) with open crowdsource efforts

2020-09-20 | Preprint
DOI: 10.1101/2020.09.18.301721
Contributors: Sharon Freshour; Susanna Kiwala; Kelsy C. Cotto; Adam C. Coffman; Joshua F. McMichael; Jonathan Song; Malachi Griffith; Obi L. Griffith; Alex H. Wagner
Source: check_circle
Crossref

Wikidata as a knowledge graph for the life sciences

eLife
2020-03-17 | Journal article
DOI: 10.7554/eLife.52614
Contributors: Andra Waagmeester; Gregory Stupp; Sebastian Burgstaller-Muehlbacher; Benjamin M Good; Malachi Griffith; Obi L Griffith; Kristina Hanspers; Henning Hermjakob; Toby S Hudson; Kevin Hybiske et al.
Source: check_circle
Crossref

Best practices for bioinformatic characterization of neoantigens for clinical utility

Genome Medicine
2019-12 | Journal article
DOI: 10.1186/s13073-019-0666-2
Contributors: Megan M. Richters; Huiming Xia; Katie M. Campbell; William E. Gillanders; Obi L. Griffith; Malachi Griffith
Source: check_circle
Crossref

Wikidata as a FAIR knowledge graph for the life sciences

2019-10-21 | Other
DOI: 10.1101/799684
Contributors: Andra Waagmeester; Gregory Stupp; Sebastian Burgstaller-Muehlbacher; Benjamin M. Good; Malachi Griffith; Obi Griffith; Kristina Hanspers; Henning Hermjakob; Toby S. Hudson; Kevin Hybiske et al.
Source: check_circle
Crossref

Stool-derived eukaryotic RNA biomarkers for detection of high-risk adenomas

2019-01-29 | Other
DOI: 10.1101/534412
Contributors: Erica K. Barnell; Yiming Kang; Andrew R. Barnell; Katie M. Campbell; Kimberly R. Kruse; Elizabeth M. Wurtzler; Malachi Griffith; Aadel A. Chaudhuri; Obi L. Griffith
Source: check_circle
Crossref

Text-mining clinically relevant cancer biomarkers for curation into the CIViC database

2018-12-20 | Other
DOI: 10.1101/500686
Contributors: Jake Lever; Martin R Jones; Arpad M Danos; Kilannin Krysiak; Melika Bonakdar; Jasleen Grewal; Luka Culibrk; Obi L Griffith; Malachi Griffith; Steven JM Jones
Source: check_circle
Crossref

Identification of community-consensus clinically relevant variants and development of single molecule molecular inversion probes using the CIViC database

2018-11-28 | Other
DOI: 10.1101/479394
Contributors: Erica K. Barnell; Adam Waalkes; Kelsi Penewit; Katie M. Campbell; Zachary L. Skidmore; Colin C. Pritchard; Todd A. Fehniger; Ravindra Uppaluri; Ramaswamy Govindan; Malachi Griffith et al.
Source: check_circle
Crossref

Spontaneous aggressive ERα+ mammary tumor model is driven by Kras activation

2018-10-16 | Other
DOI: 10.1101/442624
Contributors: Katie M Campbell; Kathleen A O'Leary; Debra E Rugowski; William A Mulligan; Erica K Barnell; Zachary L Skidmore; Kilannin Krysiak; Malachi Griffith; Linda A Schuler; Obi L Griffith
Source: check_circle
Crossref

DGIdb 3.0: a redesign and expansion of the drug–gene interaction database

Nucleic Acids Research
2018-01-04 | Journal article
DOI: 10.1093/nar/gkx1143
Contributors: Kelsy C Cotto; Alex H Wagner; Yang-Yang Feng; Susanna Kiwala; Adam C Coffman; Gregory Spies; Alex Wollam; Nicholas C Spies; Obi L Griffith; Malachi Griffith
Source: check_circle
Crossref

DoCM: a database of curated mutations in cancer

Nature Methods
2016-10-29 | Journal article
DOI: 10.1038/nmeth.4000
Contributors: Benjamin J Ainscough; Malachi Griffith; Adam C Coffman; Alex H Wagner; Jason Kunisaki; Mayank NK Choudhary; Joshua F McMichael; Robert S Fulton; Richard K Wilson; Obi L Griffith et al.
Source: check_circle
Crossref

CIViC: A knowledgebase for expert-crowdsourcing the clinical interpretation of variants in cancer

2016-09-01 | Preprint
DOI: 10.1101/072892
Contributors: Malachi Griffith; Nicholas C Spies; Kilannin Krysiak; Adam C Coffman; Joshua F McMichael; Benjamin J Ainscough; Damian T Rieke; Arpad M Danos; Lynzey Kujan; Cody A Ramirez et al.
Source: check_circle
Crossref

Aromatase inhibition remodels the clonal architecture of estrogen-receptor-positive breast cancers

Nature Communications
2016-08-09 | Journal article
DOI: 10.1038/ncomms12498
Contributors: Christopher A. Miller; Yevgeniy Gindin; Charles Lu; Obi L Griffith; Malachi Griffith; Dong Shen; Jeremy Hoog; Tiandao Li; David E. Larson; Mark Watson et al.
Source: check_circle
Crossref

GenVisR: Genomic Visualizations in R

2016-03-15 | Report
DOI: 10.1101/043604
Source: check_circle
Crossref

Association between mutation clearance after induction therapy and outcomes in acute myeloid leukemia

JAMA - Journal of the American Medical Association
2015 | Journal article
DOI: 10.1001/jama.2015.9643
EID:

2-s2.0-84940545016
Contributors: Klco, J.M.; Miller, C.A.; Griffith, M.; Petti, A.; Spencer, D.H.; Ketkar-Kulkarni, S.; Wartman, L.D.; Christopher, M.; Lamprecht, T.L.; Helton, N.M. et al.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor

Nature
2015 | Journal article
DOI: 10.1038/nature13948
EID:

2-s2.0-84925500147
Contributors: Juric, D.; Castel, P.; Griffith, M.; Griffith, O.L.; Won, H.H.; Ellis, H.; Ebbesen, S.H.; Ainscough, B.J.; Ramu, A.; Iyer, G. et al.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

Epigenetic and transcriptional determinants of the human breast

Nature Communications
2015 | Journal article
DOI: 10.1038/ncomms7351
EID:

2-s2.0-84923348351
Contributors: Gascard, P.; Bilenky, M.; Sigaroudinia, M.; Zhao, J.; Li, L.; Carles, A.; Delaney, A.; Tam, A.; Kamoh, B.; Cho, S. et al.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

Erratum to Modeling precision treatment of breast cancer [Genome Biology, 14, (2013), R110]

Genome Biology
2015 | Journal article
DOI: 10.1186/s13059-015-0658-5
EID:

2-s2.0-84939132031
Contributors: Daemen, A.; Griffith, O.L.; Heiser, L.M.; Wang, N.J.; Enache, O.M.; Sanborn, Z.; Pepin, F.; Durinck, S.; Korkola, J.E.; Griffith, M. et al.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

Genome Modeling System: A Knowledge Management Platform for Genomics

PLoS Computational Biology
2015 | Journal article
DOI: 10.1371/journal.pcbi.1004274
EID:

2-s2.0-84938630124
Contributors: Griffith, M.; Griffith, O.L.; Smith, S.M.; Ramu, A.; Callaway, M.B.; Brummett, A.M.; Kiwala, M.J.; Coffman, A.C.; Regier, A.A.; Oberkfell, B.J. et al.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

Informatics for RNA Sequencing: A Web Resource for Analysis on the Cloud

PLoS Computational Biology
2015 | Journal article
DOI: 10.1371/journal.pcbi.1004393
EID:

2-s2.0-84940729658
Contributors: Griffith, M.; Walker, J.R.; Spies, N.C.; Ainscough, B.J.; Griffith, O.L.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

Mutant U2AF1 Expression Alters Hematopoiesis and Pre-mRNA Splicing In Vivo

Cancer Cell
2015 | Journal article
DOI: 10.1016/j.ccell.2015.04.008
EID:

2-s2.0-84929149702
Contributors: Shirai, C.L.; Ley, J.N.; White, B.S.; Kim, S.; Tibbitts, J.; Shao, J.; Ndonwi, M.; Wadugu, B.; Duncavage, E.J.; Okeyo-Owuor, T. et al.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

RNA-sequencing reveals oligodendrocyte and neuronal transcripts in microglia relevant to central nervous system disease

GLIA
2015 | Journal article
DOI: 10.1002/glia.22754
EID:

2-s2.0-84922761977
Contributors: Solga, A.C.; Pong, W.W.; Walker, J.; Wylie, T.; Magrini, V.; Apicelli, A.J.; Griffith, M.; Griffith, O.L.; Kohsaka, S.; Wu, G.F. et al.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

CDNA hybrid capture improves transcriptome analysis on low-input and archived samples

Journal of Molecular Diagnostics
2014 | Journal article
DOI: 10.1016/j.jmoldx.2014.03.004
EID:

2-s2.0-84902967827
Contributors: Cabanski, C.R.; Magrini, V.; Griffith, M.; Griffith, O.L.; McGrath, S.; Zhang, J.; Walker, J.; Ly, A.; Demeter, R.; Fulton, R.S. et al.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

Clonal architectures and driver mutations in metastatic melanomas

PLoS ONE
2014 | Journal article
DOI: 10.1371/journal.pone.0111153
EID:

2-s2.0-84911941605
Contributors: Ding, L.; Kim, M.; Kanchi, K.L.; Dees, N.D.; Lu, C.; Griffith, M.; Fenstermacher, D.; Sung, H.; Miller, C.A.; Goetz, B. et al.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

Functional heterogeneity of genetically defined subclones in acute myeloid leukemia

Cancer Cell
2014 | Journal article
DOI: 10.1016/j.ccr.2014.01.031
EID:

2-s2.0-84896081834
Contributors: Klco, J.M.; Spencer, D.H.; Miller, C.A.; Griffith, M.; Lamprecht, T.L.; O'Laughlin, M.; Fronick, C.; Magrini, V.; Demeter, R.T.; Fulton, R.S. et al.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

Hippo signaling influences HNF4A and FOXA2 enhancer switching during hepatocyte differentiation

Cell Reports
2014 | Journal article
DOI: 10.1016/j.celrep.2014.08.046
EID:

2-s2.0-84907996370
Contributors: Alder, O.; Cullum, R.; Lee, S.; Kan, A.C.; Wei, W.; Yi, Y.; Garside, V.C.; Bilenky, M.; Griffith, M.; Morrissy, A. et al.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

Single exon-resolution targeted chromosomal microarray analysis of known and candidate intellectual disability genes

European Journal of Human Genetics
2014 | Journal article
DOI: 10.1038/ejhg.2013.248
EID:

2-s2.0-84901066491
Contributors: Tucker, T.; Zahir, F.R.; Griffith, M.; Delaney, A.; Chai, D.; Tsang, E.; Lemyre, E.; Dobrzeniecka, S.; Marra, M.; Eydoux, P. et al.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier
grade
Preferred source (of 2)‎

DGIdb: Mining the druggable genome

Nature Methods
2013 | Journal article
DOI: 10.1038/nmeth.2689
EID:

2-s2.0-84888862866
Contributors: Griffith, M.; Griffith, O.L.; Coffman, A.C.; Weible, J.V.; Mcmichael, J.F.; Spies, N.C.; Koval, J.; Das, I.; Callaway, M.B.; Eldred, J.M. et al.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier
grade
Preferred source (of 2)‎

F11R Is a Novel Monocyte Prognostic Biomarker for Malignant Glioma

PLoS ONE
2013 | Journal article
DOI: 10.1371/journal.pone.0077571
EID:

2-s2.0-84885411121
Contributors: Pong, W.W.; Walker, J.; Wylie, T.; Magrini, V.; Luo, J.; Emnett, R.J.; Choi, J.; Cooper, M.L.; Griffith, M.; Griffith, O.L. et al.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

Modeling precision treatment of breast cancer.

Genome biology
2013 | Journal article
EID:

2-s2.0-84906213716
Contributors: Daemen, A.; Griffith, O.L.; Heiser, L.M.; Wang, N.J.; Enache, O.M.; Sanborn, Z.; Pepin, F.; Durinck, S.; Korkola, J.E.; Griffith, M. et al.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

Novel mRNA isoforms and mutations of uridine monophosphate synthetase and 5-fluorouracil resistance in colorectal cancer

Pharmacogenomics Journal
2013 | Journal article
DOI: 10.1038/tpj.2011.65
EID:

2-s2.0-84875463339
Contributors: Griffith, M.; Mwenifumbo, J.C.; Cheung, P.Y.; Paul, J.E.; Pugh, T.J.; Tang, M.J.; Chittaranjan, S.; Morin, R.D.; Asano, J.K.; Ally, A.A. et al.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

Interaction of cyclin-dependent kinase 12/CrkRS with cyclin K1 is required for the phosphorylation of the C-terminal domain of RNA polymerase II

Molecular and Cellular Biology
2012 | Journal article
DOI: 10.1128/MCB.06267-11
EID:

2-s2.0-84868681176
Contributors: Cheng, S.-W.G.; Kuzyk, M.A.; Moradian, A.; Ichu, T.-A.; Chang, V.C.-D.; Tien, J.F.; Vollett, S.E.; Griffith, M.; Marra, M.A.; Morin, G.B.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

The clonal and mutational evolution spectrum of primary triple-negative breast cancers

2012 | Journal article
DOI: 10.1038/nature10933
Part of ISSN: 0028-0836
Source: Self-asserted source
Malachi Griffith via Crossref Metadata Search
grade
Preferred source (of 2)‎

Extensive relationship between antisense transcription and alternative splicing in the human genome

Genome Research
2011 | Journal article
DOI: 10.1101/gr.113431.110
EID:

2-s2.0-79960521632
Contributors: Morrissy, A.S.; Griffith, M.; Marra, M.A.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

Nature
2011 | Journal article
DOI: 10.1038/nature10351
EID:

2-s2.0-80052029516
Contributors: Morin, R.D.; Mendez-Lago, M.; Mungall, A.J.; Goya, R.; Mungall, K.L.; Corbett, R.D.; Johnson, N.A.; Severson, T.M.; Chiu, R.; Field, M. et al.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells (Genome Research (2008) 18, (610-621))

Genome Research
2009 | Journal article
EID:

2-s2.0-66049095206
Contributors: Morin, R.D.; O'Connor, M.D.; Griffith, M.; Kuchenbauer, F.; Delaney, A.; Prabhu, A.-L.; Zhao, Y.; McDonald, H.; Zeng, T.; Hirst, M. et al.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

The completion of the Mammalian Gene Collection

Genome Research
2009 | Journal article
DOI: 10.1101/gr.095976.109
EID:

2-s2.0-73249119724
Contributors: Temple, G.; Gerhard, D.S.; Rasooly, R.; Feingold, E.A.; Good, P.J.; Robinson, C.; Mandich, A.; Derge, J.G.; Lewis, J.; Shoaf, D. et al.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells

Genome Research
2008 | Journal article
DOI: 10.1101/gr.7179508
EID:

2-s2.0-41649106136
Contributors: Morin, R.D.; O'Connor, M.D.; Griffith, M.; Kuchenbauer, F.; Delaney, A.; Prabhu, A.-L.; Zhao, Y.; McDonald, H.; Zeng, T.; Hirst, M. et al.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

Impact of whole genome amplification on analysis of copy number variants

Nucleic Acids Research
2008 | Journal article
DOI: 10.1093/nar/gkn378
EID:

2-s2.0-48349105094
Contributors: Pugh, T.J.; Delaney, A.D.; Farnoud, N.; Flibotte, S.; Griffith, M.; Li, H.I.; Qian, H.; Farinha, P.; Gascoyne, R.D.; Marra, M.A.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier

In-depth characterization of the microRNA transcriptome in a leukemia progression model

Genome Research
2008 | Journal article
DOI: 10.1101/gr.077578.108
EID:

2-s2.0-55549129277
Contributors: Kuchenbauer, F.; Morin, R.D.; Argiropoulos, B.; Petriv, O.I.; Griffith, M.; Heuser, M.; Yung, E.; Piper, J.; Delaney, A.; Prabhu, A.-L. et al.
Source: Self-asserted source
Malachi Griffith via Scopus - Elsevier
Items per page:
Page 1 of 2

Peer review (12 reviews for 7 publications/grants)

Review activity for F1000Research. (1)
Review activity for Genome medicine. (1)
Review activity for Nature biotechnology. (1)
Review activity for Nature cancer. (4)
Review activity for Nature communications (2)
Review activity for Nature genetics. (2)
Review activity for PLoS computational biology. (1)
How many people are using ORCID?