Christian Scerri (0000-0002-6499-234X)

Personal information

Biography

Christian Scerri graduated with a degree in Medicine and Surgery from the University of Malta in 1985 and obtained a Ph.D. in Molecular Genetics from the same University. For the past 30 years he has been involved in the molecular characterisation of a number of genetic conditions in Malta. He is presently a consultant geneticist at Mater Dei Hospital and a full professor within the Faculty of Medicine and Surgery, University of Malta. He has published various studies on the molecular characterisation of a number of genetic conditions and multi factorial disorders. He is one of the administrator of the recently launched Emanuele Cancer Research Foundation, a foundation formed between the President’s Trust (a charity trust of H.E. the President of Malta), Fondazione Terzo Pilastro and the University of Malta. Christian has also been a member of various task forces and strategy building teams in the field of biobanking, rare diseases, cancer and health research. He has also held the chair of the Association of European Coeliac Societies and one of its directors (2003-2012; 2016-2022) and at them moment he forms part of the working group on the strategy of the Association. He has held various national and international, public and private managerial appointments, member of editorial boards as well as international project evaluator for the Italian Coeliac Foundation and the Research Promotion Foundation (RPF) of Cyprus.

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University of Malta: Msida, MT

2011-03 to present | Full Professor (Faculty of Medicine and Surgery)

Employment

Christian Scerri

https://orcid.org/0000-0002-6499-234X

Personal information

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Biography

Activities

Employment (6)

University of Malta: Msida, MT

Department of Health: Valletta, MT

University of Malta: Msida, Malta Majjistral, MT

Department of Health: Msida, MT

University of Malta: Msida, Malta Majjistral, MT

Ministry of Health: Msida, MT

Education and qualifications (2)

University of Malta Medical School: Guardamangia, MT

University of Malta Medical School: Guardamangia, MT

Professional activities (3)

Emanuele Cancer Research Foundation Malta: Valletta, MT

European Association for Cancer Research: Nottingham, GB

Association of European Coeliac Societies: Brussels, BE

Works (50 of 58)

Copy Number Variations as Determinants of Colorectal Tumor Progression in Liquid Biopsies

PKC-mediated phosphorylation and activation of the MEK/ERK pathway as a mechanism of acquired trastuzumab resistance in HER2-positive breast cancer.

P234 The effect of calcitriol on the expression of interferon signature genes in dendritic cells and macrophages in systemic lupus erythematosus

Nurses' Experiences of Caring for Long-Term Care Residents With Dementia During the COVID-19 Pandemic.

Genome sequences of 10 SARS-CoV-2 viral strains obtained by nanopore sequencing of nasopharyngeal Swabs in Malta

Vitamin D supplementation in systemic lupus erythematosus: relationship to disease activity, fatigue and the interferon signature gene expression.

Reaching out for Help: Calls to a Mental Health Helpline Prior to and during the COVID-19 Pandemic

A loop involving NRF2, miR-29b-1-5p and AKT, regulates cell fate of MDA-MB-231 triple-negative breast cancer cells

Improved Diagnosis of Rare Disease Patients through Systematic Detection of Runs of Homozygosity

Loss of MCL1 function sensitizes the MDA-MB-231 breast cancer cells to rh-TRAIL by increasing DR4 levels.

Bead-based RNA multiplex panels for biomarker detection in oncology samples.

Illness perceptions, depression and anxiety in informal carers of persons with depression: a cross-sectional survey.

Optimization of a Multiplex RNA-based Expression Assay Using Breast Cancer Archival Material.

Parthenolide prevents resistance of MDA-MB231 cells to doxorubicin and mitoxantrone: the role of Nrf2.

CIP2A expression predicts recurrences of tamoxifen-treated breast cancer.

Ultrasound processing of liquid system(s) and its antimicrobial mechanism of action.

Suppressive role exerted by microRNA-29b-1-5p in triple negative breast cancer through SPIN1 regulation.

Environmental and lifestyle risk factors of breast cancer in Malta-a retrospective case-control study.

The Molecular and Haematological Spectrum of KLF1 in Malta

Understanding Human-Device Interaction patterns within the context of mobile nutrition

Deregulation of the protein phosphatase 2A, PP2A in cancer: complexity and therapeutic options.

Unusual roles of caspase-8 in triple-negative breast cancer cell line MDA-MB-231.

Parthenolide and DMAPT exert cytotoxic effects on breast cancer stem-like cells by inducing oxidative stress, mitochondrial dysfunction and necrosis.

Molecular Classification of Breast Cancer Patients Using Formalin-fixed Paraffin-embedded Derived RNA Samples

Systematic review with meta-analysis: early infant feeding and coeliac disease--update 2015.

Preventive and Predictive Genetics: A perspective

Human-Computer Interaction Patterns within the Mobile Nutrition Landscape: A Review of Literature

Impact on parents of HLA-DQ2/DQ8 genotyping in healthy children from coeliac families.

Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants.

Plucked human hair shafts and biomolecular medical research.

Systematic review: early infant feeding and the prevention of coeliac disease.

A European survey on biobanks: trends and issues.

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease.

P7-methylation status of the Runx2 P2 promoter in a family with ectopic maxillary canines.

The PreventCD Study design: towards new strategies for the prevention of coeliac disease.

Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin.

A case-control study of Parkinson's disease and tobacco use: gene-tobacco interactions.

Hb Valletta [beta87(F3)Thr-->Pro] and Hb Marseille/Long Island [beta2(NA2)His-->Pro; (-1)Met-(+1)Val-(+2)Pro-Leu], in a unique compound heterozygote with a normal hemoglobin phenotype.

No effects of a synonymous variant within the CD59 gene on its protein product in duodenal biopsies of coeliac individuals.

Variants within protectin (CD59) and CD44 genes linked to an inherited haplotype in a family with coeliac disease.

Review article: future research on coeliac disease - a position report from the European multistakeholder platform on coeliac disease (CDEUSSA).

A review of cis-trans interplay between DNA sequences 5' to the (G)gamma- and beta-globin genes among Hb F-Malta-I heterozygotes/homozygotes and beta-thalassemia homozygotes/compound heterozygotes, and the effects of hydroxyurea on the Hb F/F-erythrocyte; the need for large multicenter trials.

Developmental effect of the XmnI site on Ggamma-globin gene expression among newborn Hb F-Malta-I [Ggamma117(G19)His-->Arg, CAT-->CGT] heterozygotes and adult beta+ -Thalassemia homozygotes.

Health perceptions and adherence to diet.

Environmental risk factors for Parkinson's disease and parkinsonism: the Geoparkinson study.

Gene-environment interactions in parkinsonism and Parkinson's disease: the Geoparkinson study.

Molecular genetics of tetrahydrobiopterin (BH4) deficiency in the Maltese population.

Comparative Frequency of Coagulation Factor II and Coagulation Factor V Alleles among New-Born and Senior Citizens

What are the molecular switches for the various globin genes (embryonal, foetal and adult) and what triggers them?

Characterization and locus assignment of two α-globin variants present in the Maltese population: Hb St. Luke's [α95(G2)Pro→Arg] and Hb Setif [α94(G1)Asp→Tyr]