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Scopus Author ID: 24831345100
Scopus Author ID: 12807351300

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Employment (4)

Genentech Inc: South San Francisco, CA, US

2020 to present | Scientist (Small Molecule Drug Discovery)
Employment
Source: Self-asserted source
Peter Man-Un Ung

Yale University: New Haven, Connecticut, US

2019 to 2020 | Research Scientist (Department of Pharmacology)
Employment
Source: Self-asserted source
Peter Man-Un Ung

Icahn School of Medicine at Mount Sinai Department of Pharmacological Sciences: New York, NY, US

2015 to 2019 | Senior Research Scientist (Department of Pharmacological Sciences)
Employment
Source: Self-asserted source
Peter Man-Un Ung

Icahn School of Medicine at Mount Sinai: New York, NY, US

2013 to 2015 | Postdoctoral (Department of Pharmacological Sciences)
Employment
Source: Self-asserted source
Peter Man-Un Ung

Education and qualifications (2)

University of Michigan: Ann Arbor, MI, US

2006 to 2013 | PhD (Department of Medicinal Chemistry)
Education
Source: Self-asserted source
Peter Man-Un Ung

University of California San Diego: La Jolla, CA, US

2004 to 2006 | Bachelor
Education
Source: Self-asserted source
Peter Man-Un Ung

Works (31)

Identification of a G-Protein-Independent Activator of GIRK Channels

Cell Reports
2020-06 | Journal article
DOI: 10.1016/j.celrep.2020.107770
Part of ISSN: 2211-1247
Source: Self-asserted source
Peter Man-Un Ung

High-Resolution Structure and Inhibition of the Schizophrenia-Linked Pseudokinase ULK4

Journal of the American Chemical Society
2020-01-08 | Journal article
DOI: 10.1021/jacs.9b10458
Part of ISSN: 0002-7863
Part of ISSN: 1520-5126
Source: Self-asserted source
Peter Man-Un Ung

Integrated computational and Drosophila cancer model platform captures previously unappreciated chemicals perturbing a kinase network

PLOS Computational Biology
2019-04-26 | Journal article
DOI: 10.1371/journal.pcbi.1006878
Part of ISSN: 1553-7358
Source: Self-asserted source
Peter Man-Un Ung

Functional and structural analysis of rare SLC2A2 variants associated with Fanconi‐Bickel syndrome and metabolic traits

Human Mutation
2019-04-25 | Journal article
DOI: 10.1002/humu.23758
Part of ISSN: 1059-7794
Part of ISSN: 1098-1004
Source: Self-asserted source
Peter Man-Un Ung

Structures of ligand-occupied β-Klotho complexes reveal a molecular mechanism underlying endocrine FGF specificity and activity

Proceedings of the National Academy of Sciences
2019-04-16 | Journal article
DOI: 10.1073/pnas.1822055116
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Source: Self-asserted source
Peter Man-Un Ung

An IRAK1–PIN1 signalling axis drives intrinsic tumour resistance to radiation therapy

Nature Cell Biology
2019-02 | Journal article
DOI: 10.1038/s41556-018-0260-7
Part of ISSN: 1465-7392
Part of ISSN: 1476-4679
Source: Self-asserted source
Peter Man-Un Ung

Encounter and React: Computer-Guided Design of Covalent Inhibitors

Cell Chemical Biology
2019-01 | Journal article
DOI: 10.1016/j.chembiol.2018.12.009
Part of ISSN: 2451-9456
Source: Self-asserted source
Peter Man-Un Ung

KinaMetrix: a web resource to investigate kinase conformations and inhibitor space

Nucleic Acids Research
2019-01-08 | Journal article
DOI: 10.1093/nar/gky916
Part of ISSN: 0305-1048
Part of ISSN: 1362-4962
Source: Self-asserted source
Peter Man-Un Ung

Novel selective thiadiazine DYRK1A inhibitor lead scaffold with human pancreatic β-cell proliferation activity

European Journal of Medicinal Chemistry
2018-09 | Journal article
DOI: 10.1016/j.ejmech.2018.08.007
Part of ISSN: 0223-5234
Source: Self-asserted source
Peter Man-Un Ung

Redefining the Protein Kinase Conformational Space with Machine Learning

Cell Chemical Biology
2018-07 | Journal article
DOI: 10.1016/j.chembiol.2018.05.002
Part of ISSN: 2451-9456
Source: Self-asserted source
Peter Man-Un Ung

A whole-animal platform to advance a clinical kinase inhibitor into new disease space

Nature Chemical Biology
2018-03 | Journal article
DOI: 10.1038/nchembio.2556
Part of ISSN: 1552-4450
Part of ISSN: 1552-4469
Source: Self-asserted source
Peter Man-Un Ung
grade
Preferred source (of 2)‎

SLC transporters: structure, function, and drug discovery

MedChemComm
2016 | Journal article
DOI: 10.1039/c6md00005c
Part of ISSN: 2040-2503
Contributors: Claire Colas; Peter Man-Un Ung; Avner Schlessinger
Source: Self-asserted source
Peter Man-Un Ung via Crossref Metadata Search

Systems Pharmacology: An Overview

Systems Pharmacology and Pharmacodynamics
2016 | Other
DOI: 10.1007/978-3-319-44534-2_4
Part of ISBN: 9783319445328
Part of ISSN: 2210-7371
Contributors: Marc R. Birtwistle; Jens Hansen; James M. Gallo; Sreeharish Muppirisetty; Peter Man-Un Ung; Ravi Iyengar; Avner Schlessinger
Source: Self-asserted source
Peter Man-Un Ung via Crossref Metadata Search

GEN3VA: aggregation and analysis of gene expression signatures from related studies

BMC Bioinformatics
2016-11 | Journal article
DOI: 10.1186/s12859-016-1321-1
Part of ISSN: 1471-2105
Contributors: Gregory W. Gundersen; Kathleen M. Jagodnik; Holly Woodland; Nicholas F. Fernandez; Kevin Sani; Anders B. Dohlman; Peter Man-Un Ung; Caroline D. Monteiro; Avner Schlessinger; Avi Ma’ayan
Source: Self-asserted source
Peter Man-Un Ung via Crossref Metadata Search

Inhibitor Discovery for the Human GLUT1 from Homology Modeling and Virtual Screening

ACS Chemical Biology
2016-07 | Journal article
DOI: 10.1021/acschembio.6b00304
Part of ISSN: 1554-8929
Contributors: Peter Man-Un Ung; Wenxin Song; Lili Cheng; Xinbin Zhao; Hailin Hu; Ligong Chen; Avner Schlessinger
Source: Self-asserted source
Peter Man-Un Ung via Crossref Metadata Search

Molecular Basis for Redox Activation of Epidermal Growth Factor Receptor Kinase

Cell Chemical Biology
2016-07 | Journal article
DOI: 10.1016/j.chembiol.2016.05.017
Part of ISSN: 2451-9456
Contributors: Thu H. Truong; Peter Man-Un Ung; Prakash B. Palde; Candice E. Paulsen; Avner Schlessinger; Kate S. Carroll
Source: Self-asserted source
Peter Man-Un Ung via Crossref Metadata Search

Identifying binding hot spots on protein surfaces by mixed-solvent molecular dynamics: HIV-1 protease as a test case

Biopolymers
2015-10 | Journal article
DOI: 10.1002/bip.22742
Part of ISSN: 0006-3525
Contributors: Peter M. U. Ung; Phani Ghanakota; Sarah E. Graham; Katrina W. Lexa; Heather A. Carlson; J. McCammon
Source: Self-asserted source
Peter Man-Un Ung via Crossref Metadata Search

DFGmodel: Predicting Protein Kinase Structures in Inactive States for Structure-Based Discovery of Type-II Inhibitors

Biophysical Journal
2015-01 | Journal article
DOI: 10.1016/j.bpj.2014.11.2590
Part of ISSN: 0006-3495
Contributors: Peter Man-Un Ung; Avner Schlessinger
Source: Self-asserted source
Peter Man-Un Ung via Crossref Metadata Search

An Allosteric Modulator of HIV-1 Protease Shows Equipotent Inhibition of Wild-Type and Drug-Resistant Proteases

Journal of Medicinal Chemistry
2014-08 | Journal article
DOI: 10.1021/jm5008352
Part of ISSN: 0022-2623
Contributors: Peter M.-U. Ung; James B. Dunbar; Jason E. Gestwicki; Heather A. Carlson
Source: Self-asserted source
Peter Man-Un Ung via Crossref Metadata Search

Identification of Key Hinge Residues Important for Nucleotide-Dependent Allostery in E. coli Hsp70/DnaK

PLoS Computational Biology
2013-11 | Journal article
DOI: 10.1371/journal.pcbi.1003279
Part of ISSN: 1553-7358
Contributors: Peter Man-Un Ung; Andrea D. Thompson; Lyra Chang; Jason E. Gestwicki; Heather A. Carlson; Dennis R. Livesay
Source: Self-asserted source
Peter Man-Un Ung via Crossref Metadata Search

Correction to CSAR Benchmark Exercise of 2010: Selection of the Protein–Ligand Complexes

Journal of Chemical Information and Modeling
2011-09 | Journal article
DOI: 10.1021/ci200363q
Part of ISSN: 1549-9596
Contributors: James B. Dunbar; Richard D. Smith; Chao-Yie Yang; Peter Man-Un Ung; Katrina W. Lexa; Nickolay A. Khazanov; Jeanne A. Stuckey; Shaomeng Wang; Heather A. Carlson
Source: Self-asserted source
Peter Man-Un Ung via Crossref Metadata Search

CSAR Benchmark Exercise of 2010: Combined Evaluation Across All Submitted Scoring Functions

Journal of Chemical Information and Modeling
2011-09 | Journal article
DOI: 10.1021/ci200269q
Part of ISSN: 1549-9596
Contributors: Richard D. Smith; James B. Dunbar; Peter Man-Un Ung; Emilio X. Esposito; Chao-Yie Yang; Shaomeng Wang; Heather A. Carlson
Source: Self-asserted source
Peter Man-Un Ung via Crossref Metadata Search

CSAR Benchmark Exercise of 2010: Selection of the Protein–Ligand Complexes

Journal of Chemical Information and Modeling
2011-09 | Journal article
DOI: 10.1021/ci200082t
Part of ISSN: 1549-9596
Contributors: James B. Dunbar; Richard D. Smith; Chao-Yie Yang; Peter Man-Un Ung; Katrina W. Lexa; Nickolay A. Khazanov; Jeanne A. Stuckey; Shaomeng Wang; Heather A. Carlson
Source: Self-asserted source
Peter Man-Un Ung via Crossref Metadata Search

Chemical Screens against a Reconstituted Multiprotein Complex: Myricetin Blocks DnaJ Regulation of DnaK through an Allosteric Mechanism

Chemistry & Biology
2011-02 | Journal article
DOI: 10.1016/j.chembiol.2010.12.010
Part of ISSN: 1074-5521
Contributors: Lyra Chang; Yoshinari Miyata; Peter M.U. Ung; Eric B. Bertelsen; Thomas J. McQuade; Heather A. Carlson; Erik R.P. Zuiderweg; Jason E. Gestwicki
Source: Self-asserted source
Peter Man-Un Ung via Crossref Metadata Search

Chemical Probes That Selectively Recognize the Earliest Aβ Oligomers in Complex Mixtures

Journal of the American Chemical Society
2010 | Journal article
DOI: 10.1021/ja106291e
Part of ISSN: 0002-7863
Contributors: Ashley A. Reinke; Peter M. U. Ung; Jerome J. Quintero; Heather A. Carlson; Jason E. Gestwicki
Source: Self-asserted source
Peter Man-Un Ung via Crossref Metadata Search

Binding of a Small Molecule at a Protein–Protein Interface Regulates the Chaperone Activity of Hsp70–Hsp40

ACS Chemical Biology
2010-06 | Journal article
DOI: 10.1021/cb1000422
Part of ISSN: 1554-8929
Contributors: Susanne Wisén; Eric B. Bertelsen; Andrea D. Thompson; Srikanth Patury; Peter Ung; Lyra Chang; Christopher G. Evans; Gladis M. Walter; Peter Wipf; Heather A. Carlson et al.
Source: Self-asserted source
Peter Man-Un Ung via Crossref Metadata Search

Mutagenesis Reveals the Complex Relationships between ATPase Rate and the Chaperone Activities ofEscherichia coliHeat Shock Protein 70 (Hsp70/DnaK)

Journal of Biological Chemistry
2010-05-03 | Journal article
DOI: 10.1074/jbc.m110.124149
Part of ISSN: 0021-9258
Contributors: Lyra Chang; Andrea D. Thompson; Peter Ung; Heather A. Carlson; Jason E. Gestwicki
Source: Self-asserted source
Peter Man-Un Ung via Crossref Metadata Search

Automated genome mining for natural products

BMC Bioinformatics
2009 | Journal article
DOI: 10.1186/1471-2105-10-185
Part of ISSN: 1471-2105
Contributors: Michael HT Li; Peter MU Ung; James Zajkowski; Sylvie Garneau-Tsodikova; David H Sherman
Source: Self-asserted source
Peter Man-Un Ung via Crossref Metadata Search

A poke in the eye: Inhibiting HIV-1 protease through its flap-recognition pocket

Biopolymers
2008-08 | Journal article
DOI: 10.1002/bip.20993
Part of ISSN: 0006-3525
Contributors: Kelly L. Damm; Peter M. U. Ung; Jerome J. Quintero; Jason E. Gestwicki; Heather A. Carlson
Source: Self-asserted source
Peter Man-Un Ung via Crossref Metadata Search

E230Q mutation of the catalytic subunit of cAMP-dependent protein kinase affects local structure and the binding of peptide inhibitor

Biopolymers
2006 | Journal article
DOI: 10.1002/bip.20434
Part of ISSN: 0006-3525
Contributors: Man-Un Ung; Benzhuo Lu; J. A. McCammon
Source: Self-asserted source
Peter Man-Un Ung via Crossref Metadata Search

Role of the CCAAT/Enhancer-binding Protein NFATc2 Transcription Factor Cascade in the Induction of Secretory Phospholipase A2

Journal of Biological Chemistry
2006-02 | Journal article
DOI: 10.1074/jbc.m511214200
Part of ISSN: 0021-9258
Contributors: Teddy T. C. Yang; Peter M. U. Ung; Mercedes Rincón; Chi-Wing Chow
Source: Self-asserted source
Peter Man-Un Ung via Crossref Metadata Search

Peer review (5 reviews for 1 publication/grant)

Review activity for Journal of medicinal chemistry. (5)
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