Personal information

GPCR, Arrestin, Cannabinoid
New Zealand, United States

Activities

Employment (1)

Columbia University: New York, US

2022-09-01 to present | Postdoctoral Research Scientist (Psychiatry)
Employment
Source: Self-asserted source
Jamie J. Manning

Education and qualifications (2)

University of Auckland: Auckland, Auckland, NZ

Bachelor's of Science (Honours) (Pharmacology and Clinical Pharmacology)
Education
Source: Self-asserted source
Jamie J. Manning

University of Otago: Dunedin, Otago, NZ

2018-11-01 to 2022-06-15 | Doctor of Philosophy (Pharmacology and Toxicology)
Education
Source: Self-asserted source
Jamie J. Manning

Works (16)

GPCR kinase subtype requirements for arrestin-2 and-3 translocation to the cannabinoid CB<sub>1 </sub>receptor and the consequences on G protein signalling

Biochemical Pharmacology
2024 | Journal article
Contributors: Manning, Jamie J.; Finlay, David B.; Glass, Michelle
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Positive allosteric modulation of the cannabinoid CB<sub>1</sub> receptor potentiates endocannabinoid signalling and changes ERK1/2 phosphorylation kinetics

British Journal of Pharmacology
2024 | Journal article
Contributors: Green, Hayley M.; Manning, Jamie J.; Greig, Ian R.; Ross, Ruth A.; Finlay, David B.; Glass, Michelle
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Promiscuous G-protein activation by the calcium-sensing receptor

Nature
2024 | Journal article
Contributors: Zuo, Hao; Park, Jinseo; Frangaj, Aurel; Ye, Jianxiang; Lu, Guanqi; Manning, Jamie J.; Asher, Wesley B.; Lu, Zhengyuan; Hu, Guo-bin; Wang, Liguo et al.
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A novel "activation switch" motif common to all aminergic receptors

ChemRxiv
2023 | Journal article
Contributors: Lee, Kuo Hao; Manning, Jamie J; Javitch, Jonathan; Shi, Lei
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A Novel "Activation Switch" Motif Common to All Aminergic Receptors

Journal of Chemical Information and Modeling
2023 | Journal article
Contributors: Lee, Kuo Hao; Manning, Jamie J.; Javitch, Jonathan; Shi, Lei
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Cannabinoid 1 (CB<sub>1</sub>) receptor arrestin subtype-selectivity and phosphorylation dependence

British Journal of Pharmacology
2023 | Journal article
Contributors: Manning, Jamie J.; Rawcliffe, Gabriel; Finlay, David B.; Glass, Michelle
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Methods for automating the analysis of live-cell single-molecule FRET data

Frontiers in Cell and Developmental Biology
2023-08-15 | Journal article
Part of ISSN: 2296-634X
Contributors: Jozsef Meszaros; Peter Geggier; Jamie J. Manning; Wesley B. Asher; Jonathan A. Javitch
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Jamie J. Manning
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Defining Steric Requirements at CB1 and CB2 Cannabinoid Receptors Using Synthetic Cannabinoid Receptor Agonists 5F-AB-PINACA, 5FADB-PINACA, PX-1, PX-2, NNL-1, and Their Analogues

ACS Chemical Neuroscience
2022 | Journal article
Contributors: Markham, Jack; Sparkes, Eric; Boyd, Rochelle; Chen, Shuli; Manning, Jamie J.; Finlay, David; Lai, Felcia; McGregor, Eila; Maloney, Callan J.; Gerona, Roy R. et al.
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Putative Synthetic Cannabinoids MEPIRAPIM, 5F-BEPIRAPIM (NNL-2), and Their Analogues Are T-Type Calcium Channel (Ca<sub>V</sub>3) Inhibitors

ACS Chemical Neuroscience
2022-05-04 | Journal article
Part of ISSN: 1948-7193
Part of ISSN: 1948-7193
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Jamie J. Manning
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Pharmacological selection of cannabinoid receptor effectors: Signalling, allosteric modulation and bias

Neuropharmacology
2021 | Journal article
Contributors: Manning, Jamie J.; Green, Hayley M.; Glass, Michelle; Finlay, David B.
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Exploring Stereochemical and Conformational Requirements at Cannabinoid Receptors for Synthetic Cannabinoids Related to SDB-006, 5F-SDB-006, CUMYL-PICA, and 5F-CUMYL-PICA

ACS Chemical Neuroscience
2020 | Journal article
Contributors: Ametovski, Adam; Macdonald, Christa; Manning, Jamie J.; Haneef, S. A. Syed; Santiago, Marina; Martin, Lewis; Sparkes, Eric; Reckers, Andrew; Gerona, Roy R.; Connor, Mark et al.
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Signalling profiles of a structurally diverse panel of synthetic cannabinoid receptor agonists

Biochemical Pharmacology
2020-05 | Journal article
Part of ISSN: 0006-2952
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Jamie J. Manning
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The chemistry and pharmacology of putative synthetic cannabinoid receptor agonist (SCRA) new psychoactive substances (NPS) 5F-PY-PICA, 5F-PY-PINACA, and their analogs

Drug Testing and Analysis
2019 | Journal article
Contributors: Banister, Samuel D.; Kevin, Richard C.; Martin, Lewis; Adams, Axel; Macdonald, Christa; Manning, Jamie J.; Boyd, Rochelle; Cunningham, Michael; Stevens, Marc Y.; McGregor, Lain S. et al.
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Do Toxic Synthetic Cannabinoid Receptor Agonists Have Signature in Vitro Activity Profiles? A Case Study of AMB-FUBINACA

ACS Chemical Neuroscience
2019-10-16 | Journal article
Part of ISSN: 1948-7193
Part of ISSN: 1948-7193
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Jamie J. Manning
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CUMYL-4CN-BINACA Is an Efficacious and Potent Pro-Convulsant Synthetic Cannabinoid Receptor Agonist

Frontiers in Pharmacology
2019-05-29 | Journal article
Part of ISSN: 1663-9812
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Jamie J. Manning
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Development of selective, fluorescent cannabinoid type 2 receptor ligands based on a 1,8-naphthyridin-2-(1<i>H</i>)-one-3-carboxamide scaffold

MedChemComm
2018-10-23 | Journal article
Part of ISSN: 2040-2503
Part of ISSN: 2040-2511
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Jamie J. Manning
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