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ResearcherID: N-4208-2017
Scopus Author ID: 57117740100
ResearcherID: N-4208-2017

Countries

Czech Republic, Germany

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Employment (3)

University Medical Center Hamburg-Eppendorf: Hamburg, Hamburg, DE

2021-08-01 to present | Postdoctoral researcher (Center for Anesthesiology and Intensive Care Medicine)
Employment
Source: Self-asserted source
Pavel Adamek

Institute of Physiology: Prague, CZ

2019-07-01 to 2021-07-31 | Postdoctoral researcher (Laboratory of Pain Research)
Employment
Source: Self-asserted source
Pavel Adamek

Institute of Physiology: Prague, CZ

2014-10-01 to 2019-06-30 | PhD student (full time contract) (Functional morphology)
Employment
Source: Self-asserted source
Pavel Adamek

Education and qualifications (1)

Faculty of Science, Charles University in Prague: Prague, CZ

PhD (Department of Physiology)
Education
Source: Self-asserted source
Pavel Adamek

Works (15)

Role of TMEM100 in mechanically insensitive nociceptor un-silencing

Nature Communications
2023-04-05 | Journal article
DOI: 10.1038/s41467-023-37602-w
Contributors: Timo A. Nees; Na Wang; Pavel Adamek; Nadja Zeitzschel; Clement Verkest; Carmen La Porta; Irina Schaefer; Julie Virnich; Selin Balkaya; Vincenzo Prato et al.
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Crossref
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Desensitization of Mu-opioid receptors in the spinal cord dorsal horn is reduced by endogenous TRPV1 agonist

Journal of Neurochemistry
2022 | Journal article
WOSUID: WOS:000844569000262
Contributors: Heles, Mario; Adamek, Pavel; Mrozkova, Petra; Spicarova, Diana; Palecek, Jiri
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Web of Science Researcher Profile Sync

MIF inhibitor (ISO-1) reduces pain hypersensitivity in a model of peripheral neuropathy

Journal of Neurochemistry
2022 | Journal article
WOSUID: WOS:000844569000263
Contributors: Pontearso, Monica; Adamek, Pavel; Heles, Mario; Slepicka, Jakub; Spicarova, Diana; Palecek, Jiri
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The molecular mechanism and physiological role of silent nociceptor activation

2022-04-10 | Preprint
DOI: 10.1101/2022.04.07.486730
Contributors: Timo A. Nees; Na Wang; Pavel Adamek; Clement Verkest; Carmen La Porta; Irina Schaefer; Julie Virnich; Selin Balkaya; Vincenzo Prato; Chiara Morelli et al.
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Crossref

Dual PI3Kδ/γ Inhibitor Duvelisib Prevents Development of Neuropathic Pain in Model of Paclitaxel-Induced Peripheral Neuropathy

The Journal of Neuroscience
2022-03-02 | Journal article
DOI: 10.1523/JNEUROSCI.1324-21.2021
Contributors: Pavel Adamek; Mario Heles; Anirban Bhattacharyya; Monica Pontearso; Jakub Slepicka; Jiri Palecek
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Crossref
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Chemokine CCL2 prevents opioid-induced inhibition of nociceptive synaptic transmission in spinal cord dorsal horn

Journal of Neuroinflammation
2021-12-02 | Journal article
DOI: 10.1186/s12974-021-02335-4
Part of ISSN: 1742-2094
Source: Self-asserted source
Pavel Adamek
grade
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PI3K inhibition reduces mechanical allodynia and sensitization of spinal TRPV1 in a model of paclitaxel-induced neuropathy

Journal of Neurochemistry
2019 | Journal article
WOSUID: WOS:000478639800195
Contributors: Adamek, P.; Heles, M.; Palecek, J.
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PI3K inhibition reduces mechanical allodynia and sensitization of spinal TRPV1 receptors in a model of paclitaxel-induced painful neuropathy

IBRO Reports
2019-09 | Conference abstract
DOI: 10.1016/j.ibror.2019.07.910
Part of ISSN: 2451-8301
Source: Self-asserted source
Pavel Adamek
grade
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Peripheral inflammation affects modulation of nociceptive synaptic transmission in the spinal cord induced by N-arachidonoylphosphatidylethanolamine

British Journal of Pharmacology
2018 | Journal article
DOI: 10.1111/BPH.13849
WOSUID: WOS:000434071600015
Contributors: Nerandzic, Vladimir; Mrozkova, Petra; Adamek, Pavel; Spicarova, Diana; Nagy, Istvan; Palecek, Jiri
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Mechanical allodynia and enhanced responses to capsaicin are mediated by PI3K in a paclitaxel model of peripheral neuropathy

Neuropharmacology
2018-11 | Journal article
DOI: 10.1016/j.neuropharm.2018.11.027
Contributors: Pavel Adamek; Mario Heles; Jiri Palecek
Source: check_circle
Crossref

Function of presynaptic TRPV1 receptors in the spinal cord dorsal horn is modulated by chemotherapeutic drug paclitaxel

Journal of Neurochemistry
2017 | Journal article
WOSUID: WOS:000407425300623
Contributors: Adamek, P.; Palecek, J.
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TRPV1 Receptors Contribute to Paclitaxel-Induced c-Fos Expression in Spinal Cord Dorsal Horn Neurons

Physiological Research
2017 | Journal article
DOI: 10.33549/PHYSIOLRES.933613
WOSUID: WOS:000405692500019
Contributors: Kalynovska, N.; Adamek, P.; Palecek, J.
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The NAv1.7 blocker protoxin II reduces burn injury-induced spinal nociceptive processing.

Journal of molecular medicine (Berlin, Germany)
2017-10 | Journal article
DOI: 10.1007/s00109-017-1599-0
PMID: 29063143
PMC: PMC5750333
Contributors: Torres-Pérez JV; Adamek P; Palecek J; Vizcaychipi M; Nagy I; Varga A
Source: Self-asserted source
Pavel Adamek via Europe PubMed Central
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The Cancer Chemotherapeutic Paclitaxel Increases Human and Rodent Sensory Neuron Responses to TRPV1 by Activation of TLR4.

2015-09 | Journal article
DOI: 10.1523/JNEUROSCI.1956-15.2015
PMID: 26424893
PMC: PMC4588613
Contributors: Li Y; Adamek P; Zhang H; Tatsui CE; Rhines LD; Mrozkova P; Li Q; Kosturakis AK; Cassidy RM; Harrison DS et al.
Source: Self-asserted source
Pavel Adamek via Europe PubMed Central
grade
Preferred source (of 4)‎

TRPV1 receptor inhibition decreases CCL2-induced hyperalgesia.

2014-06 | Journal article
DOI: 10.1016/j.neuropharm.2014.01.041
PMID: 24495396
Contributors: Spicarova D; Adamek P; Kalynovska N; Mrozkova P; Palecek J
Source: Self-asserted source
Pavel Adamek via Europe PubMed Central
grade
Preferred source (of 4)‎

Peer review (9 reviews for 7 publications/grants)

Review activity for Cannabis and cannabinoid research. (1)
Review activity for Drug design, development and therapy (1)
Review activity for Histology and histopathology. (1)
Review activity for Natural product communications. (1)
Review activity for Neuroscience letters. (1)
Review activity for Physiological Research. (3)
Review activity for Toxicology and applied pharmacology. (1)
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