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Employment (2)

Institut de Recherche sur le Cancer et le Vieillissement: Nice, Provence-Alpes-Côte d'Azu, FR

2021-12-01 to present | Group Leader
Employment
Source: Self-asserted source
Eirini Trompouki

Max-Planck-Institut für Immunbiologie und Epigenetik: Freiburg, DE

2013-09-01 to 2021-11-30 | Group Leader (Cellular and molecular immunology)
Employment
Source: Self-asserted source
Eirini Trompouki

Works (47)

ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA.

Cell reports
2024-10 | Journal article
Contributors: Greiner-Tollersrud OK; Krausz M; Boehler V; Polyzou A; Seidl M; Spahiu A; Abdullah Z; Andryka-Cegielski K; Dominick FI; Huebscher K et al.
Source: Self-asserted source
Eirini Trompouki via Europe PubMed Central

PD-L1 blockade immunotherapy rewires cancer-induced emergency myelopoiesis.

Frontiers in immunology
2024-10 | Journal article
Contributors: Boumpas A; Papaioannou AS; Bousounis P; Grigoriou M; Bergo V; Papafragkos I; Tasis A; Iskas M; Boon L; Makridakis M et al.
Source: Self-asserted source
Eirini Trompouki via Europe PubMed Central

p16<sup>High</sup>immune cell - controlled disease tolerance as a broad defense and healthspan extending strategy

2024-07 | Preprint
Contributors: Triana-Martinez F; Pierantoni A; Graca D; Bergo V; Emelyanov A; Grigorash BB; Tsuji S; Nakano S; Grosse L; Brglez V et al.
Source: Self-asserted source
Eirini Trompouki via Europe PubMed Central

Assessment of a novel NRAS in-frame tandem duplication causing a myelodysplastic/myeloproliferative neoplasm.

Experimental hematology
2024-03 | Journal article
Contributors: Beckmann CCA; Ramamoorthy S; Trompouki E; Driever W; Schwarz-Furlan S; Strahm B; Yoshimi A; Niemeyer CM; Erlacher M; Kapp FG
Source: Self-asserted source
Eirini Trompouki via Europe PubMed Central

Nucleic acid-induced inflammation on hematopoietic stem cells

Experimental Hematology
2024-03 | Journal article
Contributors: Giang To Vu; Valerie Awad; Maria Feliz Norberto; Teresa V. Bowman; Eirini Trompouki
Source: check_circle
Crossref

cGAS-STING is responsible for aging of telomerase deficient zebrafish

2024-03-12 | Preprint
Contributors: Naz Şerifoğlu; Giulia Allavena; Bruno Bastos-Lopes; Marta Marzullo; Pavlos Bousounis; Eirini Trompouki; Miguel Godinho Ferreira
Source: check_circle
Crossref

Targeting Heterochromatin Eliminates Chronic Myelomonocytic Leukemia Malignant Stem Cells Through Reactivation of Retroelements and Innate Immune pathways

2024-02 | Preprint
Contributors: Hidaoui D; Porquet A; Chelbi R; Bohm M; Polyzou A; Alcazer V; Depil S; Imanci A; Morabito M; Renneville A et al.
Source: Self-asserted source
Eirini Trompouki via Europe PubMed Central

PD-L1 blockade immunotherapy rewires cancer emergency myelopoiesis

2023-12 | Preprint
Contributors: Boumpas A; Papaioannou A; Bousounis P; Grigoriou M; Bergo V; Papafragkos I; Tasis A; Iskas M; Boon L; Makridakis M et al.
Source: Self-asserted source
Eirini Trompouki via Europe PubMed Central

Transposable elements in normal and malignant hematopoiesis

Disease Models & Mechanisms
2023-08-01 | Journal article
Contributors: Eline Lemerle; Eirini Trompouki
Source: check_circle
Crossref

Hematopoietic heterogeneity starts at the hemogenic endothelium.

Cell research
2023-06 | Journal article
Contributors: Lemerle E; Trompouki E
Source: Self-asserted source
Eirini Trompouki via Europe PubMed Central

Progress and challenges in stem cell biology.

Nature cell biology
2023-02-01 | Journal article
Contributors: Apostolou E; Blau H; Chien K; Lancaster MA; Tata PR; Trompouki E; Watt FM; Zeng YA; Zernicka-Goetz M
Source: Self-asserted source
Eirini Trompouki

TFEB induces mitochondrial itaconate synthesis to suppress bacterial growth in macrophages.

Nature metabolism
2022-07-21 | Journal article
Contributors: Ev-Marie Schuster; Epple MW; Katharina M. Glaser; Michael Mihlan; Lucht K; Zimmermann JA; Bremser A; Polyzou A; Obier N; Cabezas-Wallscheid et al.
Source: Self-asserted source
Eirini Trompouki

Sensing Stemness

Current Stem Cell Reports
2021-12 | Journal article
Contributors: Teresa V. Bowman; Eirini Trompouki
Source: check_circle
Crossref

Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity.

Cell stem cell
2021-10 | Journal article
Contributors: Schönberger K; Obier N; Romero-Mulero MC; Cauchy P; Mess J; Pavlovich PV; Zhang YW; Mitterer M; Rettkowski J; Lalioti ME et al.
Source: Self-asserted source
Eirini Trompouki via Europe PubMed Central

ZFP451-mediated SUMOylation of SATB2 drives embryonic stem cell differentiation

Genes & Development
2021-08-01 | Journal article
Contributors: Gustavo Antonio Urrutia; Haribaskar Ramachandran; Pierre Cauchy; Kyungjin Boo; Senthilkumar Ramamoorthy; Soeren Boller; Esen Dogan; Thomas Clapes; Eirini Trompouki; Maria-Elena Torres-Padilla et al.
Source: check_circle
Crossref

Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration.

Nature cell biology
2021-07-12 | Journal article
Source: Self-asserted source
Eirini Trompouki

Inflammation, Aging and Hematopoiesis: A Complex Relationship.

Cells
2021-06-04 | Journal article
Source: Self-asserted source
Eirini Trompouki

Mixing “good and bad” annoys neutrophils

Blood
2021-03-11 | Journal article
Contributors: Eirini Trompouki
Source: check_circle
Crossref

New tools for 'ZEBRA-FISHING'.

Briefings in functional genomics
2021-02-19 | Journal article
Source: Self-asserted source
Eirini Trompouki

Common variants in signaling transcription-factor-binding sites drive phenotypic variability in red blood cell traits

Nature Genetics
2020-12 | Journal article
Contributors: Avik Choudhuri; Eirini Trompouki; Brian J. Abraham; Leandro M. Colli; Kian Hong Kock; William Mallard; Min-Lee Yang; Divya S. Vinjamur; Alireza Ghamari; Audrey Sporrij et al.
Source: check_circle
Crossref

Dynamic Cardiolipin Synthesis Is Required for CD8<sup>+</sup> T Cell Immunity.

Cell metabolism
2020-12 | Journal article
Contributors: Corrado M; Edwards-Hicks J; Villa M; Flachsmann LJ; Sanin DE; Jacobs M; Baixauli F; Stanczak M; Anderson E; Azuma M et al.
Source: Self-asserted source
Eirini Trompouki via Europe PubMed Central

Repetitive Elements Trigger RIG-I-like Receptor Signaling that Regulates the Emergence of Hematopoietic Stem and Progenitor Cells.

Immunity
2020-11-06 | Journal article
Source: Self-asserted source
Eirini Trompouki

DOT1L-mediated murine neuronal differentiation associates with H3K79me2 accumulation and preserves SOX2-enhancer accessibility

Nature Communications
2020-10-15 | Journal article
Contributors: Francesco Ferrari; Laura Arrigoni; Henriette Franz; Annalisa Izzo; Ludmila Butenko; Eirini Trompouki; Tanja Vogel; Thomas Manke
Source: check_circle
Crossref

CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation.

Proceedings of the National Academy of Sciences of the United States of America
2020-09 | Journal article
Contributors: Hsu J; Huang HT; Lee CT; Choudhuri A; Wilson NK; Abraham BJ; Moignard V; Kucinski I; Yu S; Hyde RK et al.
Source: Self-asserted source
Eirini Trompouki via Europe PubMed Central

DOT1L Methyltransferase Activity Preserves SOX2-Enhancer Accessibility And Prevents Activation of Repressed Genes In Murine Stem Cells

2020-02-03 | Preprint
Contributors: F. Ferrari; L. Arrigoni; H. Franz; L. Butenko; E. Trompouki; T. Vogel; T. Manke
Source: check_circle
Crossref

Protection from UV light is an evolutionarily conserved feature of the haematopoietic niche

Nature
2018 | Journal article
Source: Self-asserted source
Eirini Trompouki

Bloody Zebrafish: Novel Methods in Normal and Malignant Hematopoiesis.

Frontiers in cell and developmental biology
2018-10 | Journal article
Contributors: de Pater E; Trompouki E
Source: Self-asserted source
Eirini Trompouki via Europe PubMed Central

A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways.

Nature communications
2018-08 | Journal article
Contributors: Piragyte I; Clapes T; Polyzou A; Klein Geltink RI; Lefkopoulos S; Yin N; Cauchy P; Curtis JD; Klaeylé L; Langa X et al.
Source: Self-asserted source
Eirini Trompouki via Europe PubMed Central

Editorial: Inflammatory Signaling in Bone Marrow Failure and Hematopoietic Malignancy

Frontiers in immunology
2017 | Journal article
Source: Self-asserted source
Eirini Trompouki

From the bedside to the bench: new discoveries on blood cell fate and function

Experimental hematology
2017 | Journal article
Source: Self-asserted source
Eirini Trompouki

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis

American journal of human genetics
2017 | Journal article
Source: Self-asserted source
Eirini Trompouki

Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis

Developmental cell
2016 | Journal article
Source: Self-asserted source
Eirini Trompouki

MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis

Cell stem cell
2016 | Journal article
Source: Self-asserted source
Eirini Trompouki

Stress and Non-Stress Roles of Inflammatory Signals during HSC Emergence and Maintenance

Frontiers in immunology
2016 | Journal article
Source: Self-asserted source
Eirini Trompouki

Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling

eLife
2015 | Journal article
Source: Self-asserted source
Eirini Trompouki

Fish provide ID(H)eas on targeting leukemia

Blood
2015 | Journal article
Source: Self-asserted source
Eirini Trompouki

Bloody signals: from birth to disease and death

Experimental hematology
2014 | Conference paper
Source: Self-asserted source
Eirini Trompouki

Linking hematopoietic regeneration to developmental signaling pathways: a story of BMP and Wnt

Cell cycle (Georgetown, Tex.)
2012 | Journal article
Source: Self-asserted source
Eirini Trompouki

Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway

Developmental cell
2012 | Journal article
Source: Self-asserted source
Eirini Trompouki

Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR

Developmental biology
2012 | Journal article
Source: Self-asserted source
Eirini Trompouki

Chromatin immunoprecipitation in adult zebrafish red cells

Methods in cell biology
2011 | Journal article
Source: Self-asserted source
Eirini Trompouki

Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration

Cell
2011 | Journal article
Source: Self-asserted source
Eirini Trompouki

Small molecule screen in zebrafish and HSC expansion

Methods in molecular biology (Clifton, N.J.)
2010 | Journal article
Source: Self-asserted source
Eirini Trompouki

Thymocyte-specific truncation of the deubiquitinating domain of CYLD impairs positive selection in a NF-kappaB essential modulator-dependent manner

Journal of immunology (Baltimore, Md. : 1950)
2010 | Journal article
Source: Self-asserted source
Eirini Trompouki

Truncation of the catalytic domain of the cylindromatosis tumor suppressor impairs lung maturation

Neoplasia (New York, N.Y.)
2009 | Journal article
Source: Self-asserted source
Eirini Trompouki

NF-kappaB is essential for induction of CYLD, the negative regulator of NF-kappaB: evidence for a novel inducible autoregulatory feedback pathway

The Journal of biological chemistry
2004 | Journal article
Source: Self-asserted source
Eirini Trompouki

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

Nature
2003 | Journal article
Source: Self-asserted source
Eirini Trompouki

Peer review (17 reviews for 8 publications/grants)

Review activity for BMC biology. (1)
Review activity for Cell discovery. (1)
Review activity for Cell research (1)
Review activity for EMBO journal. (2)
Review activity for Nature aging. (2)
Review activity for Nature cell biology (5)
Review activity for Nature communications (4)
Review activity for Nature immunology. (1)