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Scopus Author ID: 14069177700
Scopus Author ID: 55985939100
Loop profile: 2769420

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Employment (5)

University of Life Sciences in Poznań: Poznań, PL

2024 to present | Associate Professor / Head of Laboratory of RNA Biology (Department of Biochemistry and Biotechnology)
Employment
Source: Self-asserted source
Ewa Stepniak-Konieczna

Adam Mickiewicz University in Poznań: Poznań, PL

2015 to 2023 | Assistant Professor (Faculty of Biology, Institute of Molecular Biology and Biotechnology)
Employment
Source: Self-asserted source
Ewa Stepniak-Konieczna

Adam Mickiewicz University in Poznań: Poznan, PL

2012 to 2015 | postdoc (Faculty of Biology, Institute of Molecular Biology and Biotechnology)
Employment
Source: Self-asserted source
Ewa Stepniak-Konieczna

University of Washington: Seattle, WA, US

2010 to 2011 | postdoc (Department of Medicine, Division of Medical Genetics)
Employment
Source: Self-asserted source
Ewa Stepniak-Konieczna

Fred Hutchinson Cancer Center: Seattle, WA, US

2007 to 2009 | postdoc (Basic Sciences Division, Human Biology Division)
Employment
Source: Self-asserted source
Ewa Stepniak-Konieczna

Education and qualifications (3)

Adam Mickiewicz University in Poznań: Poznan, PL

2021 | habilitation (Faculty of Biology)
Education
Source: Self-asserted source
Ewa Stepniak-Konieczna

University of Vienna: Vienna, AT

2006 | PhD, Molecular Biology (Research Institute of Molecular Pathology; Vienna BioCenter PhD Program)
Education
Source: Self-asserted source
Ewa Stepniak-Konieczna

University of Life Sciences in Poznań: Poznań, PL

2002 | MSc, Biotechnology
Education
Source: Self-asserted source
Ewa Stepniak-Konieczna

Funding (3)

Czynniki modulujące ekspresję genów Muscleblind-like w zdrowiu i chorobie.

2023-11-29 to 2028-11-28 | Grant
National Science Center (Krakow, PL)
URL: https://app.dimensions.ai/details/grant/grant.13904857
GRANT_NUMBER: 2022/46/E/NZ5/00088
Source: Self-asserted source
Ewa Stepniak-Konieczna via DimensionsWizard
grade
Preferred source (of 2)‎

Terapeutyczna aktywacja oraz determinanty sygnalizacyjne autoregulacyjnej ekspresji MBNL1 w dystrofii miotonicznej.

2021-01-22 to 2025-01-21 | Grant
National Science Center (Krakow, PL)
URL: https://app.dimensions.ai/details/grant/grant.9552714
GRANT_NUMBER: 2020/37/B/NZ5/01263
Source: Self-asserted source
Ewa Stepniak-Konieczna via DimensionsWizard

Wykorzystanie chemicznie modyfikowanych oligonukleotydów antysensownych w eksperymentalnej terapii Dystrofii Miotonicznej (DM).

2015-07-23 to 2019-01-22 | Grant
National Science Center (Krakow, PL)
URL: https://app.dimensions.ai/details/grant/grant.7422634
GRANT_NUMBER:

2014/15/B/NZ5/00142
Source: Self-asserted source
Ewa Stepniak-Konieczna via DimensionsWizard

Works (21)

Cyclic mismatch binding ligands interact with disease-associated CGG trinucleotide repeats in RNA and suppress their translation

Nucleic Acids Research
2021-09-20 | Journal article
DOI: 10.1093/nar/gkab669
Contributors: Patryk Konieczny; Sanjukta Mukherjee; Ewa Stepniak-Konieczna; Katarzyna Taylor; Daria Niewiadomska; Agnieszka Piasecka; Agnieszka Walczak; Anna Baud; Chikara Dohno; Kazuhiko Nakatani et al.
Source: check_circle
Crossref
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AON-induced splice-switching and DMPK pre-mRNA degradation as potential therapeutic approaches for Myotonic Dystrophy type 1

Nucleic Acids Research
2020-03-18 | Journal article
DOI: 10.1093/nar/gkaa007
Contributors: Ewa Stepniak-Konieczna; Patryk Konieczny; Piotr Cywoniuk; Julia Dluzewska; Krzysztof Sobczak
Source: check_circle
Crossref
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MBNL expression in autoregulatory feedback loops

RNA Biology
2018 | Journal article
DOI: 10.1080/15476286.2017.1384119
EID:

2-s2.0-85041128508
Contributors: Konieczny, P.; Stepniak-Konieczna, E.; Sobczak, K.
Source: Self-asserted source
Ewa Stepniak-Konieczna via Scopus - Elsevier
grade
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Autoregulation of MBNL1 function by exon 1 exclusion from MBNL1transcript

Nucleic Acids Research
2017 | Journal article
DOI: 10.1093/nar/gkw1158
EID:

2-s2.0-85030614868
Contributors: Konieczny, P.; Stepniak-Konieczna, E.; Taylor, K.; Sznajder, L.J.; Sobczak, K.
Source: Self-asserted source
Ewa Stepniak-Konieczna via Scopus - Elsevier
grade
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Modified Antisense Oligonucleotides and Their Analogs in Therapy of Neuromuscular Diseases

Modified Nucleic Acids in Biology and Medicine
2016 | Book chapter
DOI: 10.1007/978-3-319-34175-0_11
Part of ISBN: 9783319341736
Part of ISBN: 9783319341750
Part of ISSN: 2197-9731
Part of ISSN: 2197-9758
Source: Self-asserted source
Ewa Stepniak-Konieczna

Modified Antisense Oligonucleotides and Their Analogs in Therapy of Neuromuscular Diseases

2016 | Book chapter
OTHER-ID: UAMc8af247bbd5c4239882e98753faceb59
Part of OTHER-ID: UAM10c8305b514b4c3e8a5e2174ed6024f6
Part of ISBN: 978-3-319-34173-6
Contributors: Patryk Radosław Konieczny; Krzysztof Sobczak; Ewa Agnieszka Stępniak-Konieczna
Source: check_circle
Adam Mickiewicz University - Omega-PSIR

Modified Antisense Oligonucleotides and Their Analogs in Therapy of Neuromuscular Diseases

2016 | Book chapter
SOURCE-WORK-ID: UAMc8af247bbd5c4239882e98753faceb59
HANDLE: amu-prod:UAMc8af247bbd5c4239882e98753faceb59
Part of ISBN: 978-3-319-34173-6
Contributors: Patryk Radosław Konieczny; Krzysztof Sobczak; Ewa Agnieszka Stępniak-Konieczna
Source: check_circle
Adam Mickiewicz University - Omega-PSIR

Short antisense-locked nucleic acids (all-LNAs) correct alternative splicing abnormalities in myotonic dystrophy

Nucleic Acids Research
2015 | Journal article
DOI: 10.1093/nar/gkv163
EID:

2-s2.0-84941758187
Contributors: Wojtkowiak-Szlachcic, A.; Taylor, K.; Stepniak-Konieczna, E.; Sznajder, L.J.; Mykowska, A.; Sroka, J.; Thornton, C.A.; Sobczak, K.
Source: Self-asserted source
Ewa Stepniak-Konieczna via Scopus - Elsevier
grade
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Therapeutic impact of systemic AAV-mediated RNA interference in a mouse model of myotonic dystrophy

Human Molecular Genetics
2015 | Journal article
DOI: 10.1093/hmg/ddv219
EID:

2-s2.0-84941930816
Contributors: Bisset, D.R.; Stepniak-Konieczna, E.A.; Zavaljevski, M.; Wei, J.; Carter, G.T.; Weiss, M.D.; Chamberlain, J.R.
Source: Self-asserted source
Ewa Stepniak-Konieczna via Scopus - Elsevier
grade
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MBNL proteins and their target RNAs, interaction and splicing regulation

Nucleic Acids Research
2014 | Journal article
DOI: 10.1093/nar/gku767
EID:

2-s2.0-84919454027
Contributors: Konieczny, P.; Stepniak-Konieczna, E.; Sobczak, K.
Source: Self-asserted source
Ewa Stepniak-Konieczna via Scopus - Elsevier
grade
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Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules

Nature Communications
2013 | Journal article
DOI: 10.1038/ncomms3044
EID:

2-s2.0-84889102738
Contributors: Childs-Disney, J.L.; Stepniak-Konieczna, E.; Tran, T.; Yildirim, I.; Park, H.; Chen, C.Z.; Hoskins, J.; Southall, N.; Marugan, J.J.; Patnaik, S. et al.
Source: Self-asserted source
Ewa Stepniak-Konieczna via Scopus - Elsevier
grade
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Mitogen-inducible gene-6 is a negative regulator of epidermal growth factor receptor signaling in hepatocytes and human hepatocellular carcinoma

Hepatology
2010 | Journal article
DOI: 10.1002/hep.23428
EID:

2-s2.0-77950602115
Contributors: Reschke, M.; Ferby, I.; Stepniak, E.; Seitzer, N.; Horst, D.; Wagner, E.F.; Ullrichi, A.
Source: Self-asserted source
Ewa Stepniak-Konieczna via Scopus - Elsevier
grade
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Adhesive and signaling functions of cadherins and catenins in vertebrate development.

Cold Spring Harbor Perspectives in Biology
2009 | Journal article
OTHER-ID: UAMa83c29212f894d79a767eed6ac7ca3b3
EID:

77149161152

Part of OTHER-ID: WUT74154
Part of EID:

19700176402

Part of ISSN: 1943-0264
Contributors: Ewa Agnieszka Stępniak-Konieczna; Glenn L Radice; Valeri Vasioukhin
Source: check_circle
Adam Mickiewicz University - Omega-PSIR

Adhesive and signaling functions of cadherins and catenins in vertebrate development.

Cold Spring Harbor perspectives in biology
2009 | Journal article
EID:

2-s2.0-77149161152
Contributors: Stepniak, E.; Radice, G.L.; Vasioukhin, V.
Source: Self-asserted source
Ewa Stepniak-Konieczna via Scopus - Elsevier
grade
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Antagonistic control of cell fates by JNK and p38-MAPK signaling

Cell Death and Differentiation
2008 | Journal article
DOI: 10.1038/sj.cdd.4402222
EID:

2-s2.0-37349081594
Contributors: Wada, T.; Stepniak, E.; Hui, L.; Leibbrandt, A.; Katada, T.; Nishina, H.; Wagner, E.F.; Penninger, J.M.
Source: Self-asserted source
Ewa Stepniak-Konieczna via Scopus - Elsevier
grade
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Dissecting the role of cadherin-catenin proteins in mammalian epidermis

Proceedings of the National Academy of Sciences of the United States of America
2008 | Journal article
DOI: 10.1073/pnas.0808458105
EID:

2-s2.0-55749108541
Contributors: Lien, W.-H.; Stepniak, E.; Vasioukhin, V.
Source: Self-asserted source
Ewa Stepniak-Konieczna via Scopus - Elsevier
grade
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Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation

Journal of Clinical Investigation
2008 | Journal article
DOI: 10.1172/JCI37156
EID:

2-s2.0-57449109370
Contributors: Hui, L.; Zatloukal, K.; Scheuch, H.; Stepniak, E.; Wagner, E.F.
Source: Self-asserted source
Ewa Stepniak-Konieczna via Scopus - Elsevier
grade
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p38α: A suppressor of cell proliferation and tumorigenesis

Cell Cycle
2007 | Journal article
DOI: 10.4161/cc.6.20.4774
EID:

2-s2.0-35848938280
Contributors: Hui, L.; Bakiri, L.; Stepniak, E.; Wagner, E.F.
Source: Self-asserted source
Ewa Stepniak-Konieczna via Scopus - Elsevier
grade
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c-Jun/AP-1 controls liver regeneration by repressing p53/p21 and p38 MAPK activity

Genes and Development
2006 | Journal article
DOI: 10.1101/gad.390506
EID:

2-s2.0-33747377165
Contributors: Stepniak, E.; Ricci, R.; Eferl, R.; Sumara, G.; Sumara, I.; Rath, M.; Hui, L.; Wagner, E.F.
Source: Self-asserted source
Ewa Stepniak-Konieczna via Scopus - Elsevier
grade
Preferred source (of 2)‎

Use of RAPD technique in evolution studies of four species in the family Canidae

Journal of Applied Genetics
2002 | Journal article
OTHER-ID: UAMb86404f1d635455fb02ec5032c6440e4
EID:

0036045097

Part of OTHER-ID: WUT70458
Part of EID:

19180

Part of ISSN: 1234-1983
Contributors: Ewa Agnieszka Stępniak-Konieczna; Maria M. Zagalska; Marek Świtoński
Source: check_circle
Adam Mickiewicz University - Omega-PSIR

Use of RAPD technique in evolution studies of four species in the family Canidae

Journal of Applied Genetics
2002 | Journal article
EID:

2-s2.0-0036045097
Contributors: Stȩpniak, E.; Zagalska, M.M.; Świtoński, M.
Source: Self-asserted source
Ewa Stepniak-Konieczna via Scopus - Elsevier
grade
Preferred source (of 2)‎
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