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SciProfiles: 1593444

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Belgium, Netherlands

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Employment (2)

KU Leuven: Leuven, Vlaanderen, BE

2018-12-01 to present | PhD researcher (Laboratory of Gynaecological Oncology)
Employment
Source: Self-asserted source
Wout De Wispelaere

Antoni van Leeuwenhoek Nederlands Kanker Instituut: Amsterdam, Noord-Holland, NL

2019-09-01 to 2021-01-01 | PhD Researcher (Molecular Oncology & Immunology)
Employment
Source: Self-asserted source
Wout De Wispelaere

Education and qualifications (2)

KU Leuven: Leuven, Vlaanderen, BE

MSc Bioscience Engineering
Education
Source: Self-asserted source
Wout De Wispelaere

KU Leuven: Leuven, Vlaanderen, BE

BSc Bioscience engineering
Education
Source: Self-asserted source
Wout De Wispelaere

Works (12)

EXPLOITING THE IMMUNOMODULATORY EFFECTS OF PI3K/MTOR INHIBITORS TO SENSITIZE UTERINE LEIOMYOSARCOMAS TO IMMUNE CHECKPOINT BLOCKADE

2024-08-22 | Dissertation or Thesis
SOURCE-WORK-ID:

4167515
Contributors: Wout De Wispelaere; Frédéric Amant
Source: check_circle
KU Leuven

PI3K/mTOR inhibition induces tumour microenvironment remodelling and sensitises pS6<sup>high</sup> uterine leiomyosarcoma to PD‐1 blockade

Clinical and Translational Medicine
2024-05 | Journal article
DOI: 10.1002/ctm2.1655
Part of ISSN: 2001-1326
Part of ISSN: 2001-1326
Contributors: Wout De Wispelaere; Daniela Annibali; Sandra Tuyaerts; Julie Messiaen; Asier Antoranz; Gautam Shankar; Nikolina Dubroja; Alejandro Herreros‐Pomares; Regina E. M. Baiden‐Amissah; Marie‐Pauline Orban et al.
Source: Self-asserted source
Wout De Wispelaere
grade
Preferred source (of 2)‎

Chemotherapy-treated breast cancer cells activate the Wnt signaling pathway to enter a diapause-DTP state

2024-03-12 | Preprint
DOI: 10.1101/2024.03.08.584051
Contributors: Youssef El Laithy; Willy Antoni Abreu De Oliveira; Anirudh Pabba; Alessandra Qualizza; François Richard; Paraskevi Athanasouli; Carla Rios Luci; Wout De Wispelaere; Larissa Mourao; Siân Hamer et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

17P Exploiting the immune-modulatory effects of PI3K/mTOR inhibitors to enhance response to immune-checkpoint blockade in uterine leiomyosarcoma

ESMO Open
2023-03 | Conference abstract
DOI: 10.1016/j.esmoop.2023.101038
Part of ISSN: 2059-7029
Contributors: W. De Wispelaere; D. Annibali; S. Tuyaerts; J. Messiaen; A. Antoranz; R.E.M. Baiden-Amissah; T. Van Brussel; R. Schepers; G. Philips; B. Boeckx et al.
Source: Self-asserted source
Wout De Wispelaere

The Expression of the Immunoproteasome Subunit PSMB9 Is Related to Distinct Molecular Subtypes of Uterine Leiomyosarcoma

Cancers
2022 | Journal article
DOI: 10.3390/cancers14205007
Part of ISSN: 2072-6694
Source: Self-asserted source
Wout De Wispelaere
grade
Preferred source (of 4)‎

2022-RA-953-ESGO Serine metabolism remodeling after platinum-based chemotherapy is a new vulnerability in resistant ovarian cancer patients

Ovarian cancer
2022-10 | Conference abstract
DOI: 10.1136/ijgc-2022-esgo.605
Contributors: Tom van Nyen; Mélanie Planque; Lilian van Wagensveld; Esther Zaal; Lara Rizzotto; Wout de Wispelaere; Ali Talebi; Pierre-René Körner; Gabe Sonke; Hugo Horlings et al.
Source: Self-asserted source
Wout De Wispelaere

Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers

Nature Communications
2022-08-05 | Journal article
DOI: 10.1038/s41467-022-32272-6
Part of ISSN: 2041-1723
Contributors: Wout De Wispelaere
Source: Self-asserted source
Wout De Wispelaere
grade
Preferred source (of 2)‎

Next generation point-of-care test for therapeutic drug monitoring of adalimumab in patients diagnosed with autoimmune diseases

Biosensors & Bioelectronics
2022-07-15 | Journal article
DOI: 10.1016/j.bios.2022.114189
SOURCE-WORK-ID:

3711785

PMID: 35366427
Part of ISSN: 0956-5663
WOSUID:

WOS:000793106800001
Contributors: Henry Ordutowski; Francesco Dal Dosso; Wout De Wispelaere; Charlotte Van Tricht; Séverine Vermeire; Nick Geukens; Ann Gils; Dragana Spasic; jeroen Lammertyn
Source: check_circle
KU Leuven
grade
Preferred source (of 2)‎

Resistance to Immune Checkpoint Blockade in Uterine Leiomyosarcoma: What Can We Learn from Other Cancer Types?

Cancers
2021-04-23 | Journal article
DOI: 10.3390/cancers13092040
Contributors: Wout De Wispelaere; Daniela Annibali; Sandra Tuyaerts; Diether Lambrechts; Frédéric Amant
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Expanding the potential of self-powered microfluidics by combining fluid modules for blood sample preparation, drug delivery and complex liquid manipulation

Expanding the potential of self-powered microfluidics by combining fluid modules for blood sample preparation, drug delivery and complex liquid manipulation
2018-11-12 | Conference paper
SOURCE-WORK-ID:

2373590
Contributors: Francesco Dal Dosso; Wout De Wispelaere; Jaroslav Belotserkovsky; Tadej Kokalj; jeroen Lammertyn
Source: check_circle
KU Leuven

17P Exploiting the immune-modulatory effects of PI3K/mTOR inhibitors to enhance response to immune-checkpoint blockade in uterine leiomyosarcoma

Abstract Book of the ESMO Sarcoma & Rare Cancers 20-22 March 2023, Lugano, Switzerland
Conference paper
SOURCE-WORK-ID:

4163415
Contributors: Wout De Wispelaere
Source: check_circle
KU Leuven

Germline copy number variants and endometrial cancer risk

Human Genetics
Journal article
DOI: 10.1007/s00439-024-02707-9
SOURCE-WORK-ID:

4200414

PMC: PMC11576655
PMID: 39495297
Part of ISSN: 0340-6717
WOSUID:

WOS:001349313100002
Contributors: Cassie E Stylianou; George A R Wiggins; Vanessa L Lau; Joe Dennis; Andrew N Shelling; Michelle Wilson; Peter Sykes; Frédéric Amant; Daniela Annibali; Wout De Wispelaere et al.
Source: check_circle
KU Leuven
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