Personal information

Other IDs

SciProfiles: 2599694

Keywords

Cancer Genetics, Breast & Ovarian Cancer, Colorectal Cancer, Early diagnosis, Prophylactics

Countries

Pakistan, Germany

Activities

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Employment (4)

National Institute of Health: Islamabad, PK

2021-03-01 to present | Member of the Board of Governors
Employment
Source: Self-asserted source
Muhammad Usman Rashid

Shaukat Khanum Memorial Cancer Hospital and Research Center: Lahore, PK

2014-07-01 to present | Head (Basic Sciences Research)
Employment
Source: Self-asserted source
Muhammad Usman Rashid

Shaukat Khanum Memorial Cancer Hospital and Research Centre: Lahore, Punjab, PK

2006 to present | Sr. Research Scientist & Genetic Counselor (Basic Sciences)
Employment
Source: Self-asserted source
Muhammad Usman Rashid

German Cancer Research Center: Heidelberg, DE

2006 to present | Guest Scientist (Molecular Genetics of Breast Cancer)
Employment
Source: Self-asserted source
Muhammad Usman Rashid

Education and qualifications (3)

The Royal College of Pathologists: London, GB

2020-01 to present | FRCPath
Education
Source: Self-asserted source
Muhammad Usman Rashid

German Cancer Research Center: Heidelberg, DE

2002 to 2005 | PhD (Molecular Genetics of Breast Cancer)
Education
Source: Self-asserted source
Muhammad Usman Rashid

University of the Punjab: Lahore, PK

1994 to 1999 | MBBS (MD) (Punjab Medical College)
Education
Source: Self-asserted source
Muhammad Usman Rashid

Funding (1)

Contribution of Genetic and Non-Genetic Risk Factors to Ovarian Cancer in Pakistan

2022-01 to present | Grant
Shaukat Khanum Memorial Cancer Hospital and Research Centre (Lahore, PK)
Source: Self-asserted source
Muhammad Usman Rashid

Works (50 of 75)

Items per page:
Page 1 of 2

Anticipation effect in Pakistani breast cancer families with or without BRCA1/2 pathogenic variants

Cancer Epidemiology
2025-06 | Journal article
DOI: 10.1016/j.canep.2025.102782
Contributors: Noor Muhammad; Humaira Naeemi; Shumaila Arif; Ute Hamann; Muhammad Usman Rashid
Source: check_circle
Crossref

Predominance of MGMT promoter methylation among Pakistani glioblastoma patients

Molecular Biology Reports
2024-12 | Journal article
DOI: 10.1007/s11033-024-09363-2
Contributors: Noor Muhammad; Samir Fasih; Bilal Malik; Shahid Hameed; Asif Loya; Muhammad Usman Rashid
Source: check_circle
Crossref

Contribution of constitutional BRCA1 promoter methylation to early-onset and familial breast cancer patients from Pakistan

Breast Cancer Research and Treatment
2023-11 | Journal article
DOI: 10.1007/s10549-023-07068-x
Contributors: Noor Muhammad; Ayesha Azeem; Muhammad Abu Bakar; Karolina Prajzendanc; Asif Loya; Anna Jakubowska; Ute Hamann; Muhammad Usman Rashid
Source: check_circle
Crossref

Spectrum and Frequency of Germline <i>FANCM</i> Protein-Truncating Variants in 44,803 European Female Breast Cancer Cases

Cancers
2023-06 | Journal article
DOI: 10.3390/cancers15133313
Contributors: Gisella Figlioli; Amandine Billaud; Qin Wang; Manjeet K. Bolla; Joe Dennis; Michael Lush; Anders Kvist; Muriel A. Adank; Thomas U. Ahearn; Natalia N. Antonenkova et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

Genetic analysis of ACE2 peptidase domain in SARS-CoV-2-positive and SARS-CoV-2-negative individuals from Pakistan

Molecular Biology Reports
2023-05 | Journal article
DOI: 10.1007/s11033-023-08315-6
Contributors: Noor Muhammad; Humaira Naeemi; Ayesha Azeem; Rida Sadaqat; Umara Shehzad; Kashif Siddique; Usman Hassan; Aun Raza; Muhammad Usman Rashid
Source: check_circle
Crossref

Prevalence of FANCM germline variants in BRCA1/2 negative breast and/or ovarian cancer patients from Pakistan

Familial Cancer
2023-01 | Journal article
DOI: 10.1007/s10689-022-00304-1
Contributors: Muhammad Usman Rashid; Noor Muhammad; Umara Shehzad; Faiz Ali Khan; Asif Loya; Ute Hamann
Source: check_circle
Crossref

The Significance of Erythroblast Transformation Specific (Ets) Transcription Factors in Breast Cancer Progression: A Meta-Analysis

Pakistan Journal of Zoology
2022 | Journal article
DOI: 10.17582/journal.pjz/20220119060146
Part of ISSN: 0030-9923
Contributors: Sidra Mumtaz
Source: Self-asserted source
Muhammad Usman Rashid

Contribution of germline PALB2 variants to an unselected and prospectively registered pancreatic cancer patient cohort in Pakistan

HPB
2022-12 | Journal article
DOI: 10.1016/j.hpb.2022.09.003
Contributors: Noor Muhammad; Rida Sadaqat; Humaira Naeemi; Iqra Masood; Usman Hassan; Bushra Ijaz; Faisal Hanif; Aamir A. Syed; Muhammed A. Yusuf; Muhammad U. Rashid
Source: check_circle
Crossref

Genetic analysis of ACE2 peptidase domain in SARS-CoV-2-positive and SARS-CoV-2-negative individuals from Pakistan

2022-11-23 | Preprint
DOI: 10.21203/rs.3.rs-2287964/v1
Contributors: Noor Muhammad; Humaira Naeemi; Ayesha Azeem; Rida Sadaqat; Umara Shehzad; Kashif Siddique; Usman Hassan; Aun Raza; Muhammad Usman Rashid
Source: check_circle
Crossref

Chasing the origin of 23 recurrent BRCA1 mutations in Pakistani breast and ovarian cancer patients

International Journal of Cancer
2022-08 | Journal article
DOI: 10.1002/ijc.34016
Contributors: Muhammad Usman Rashid; Noor Muhammad; Humaira Naeemi; Umara Shehzad; Ute Hamann
Source: check_circle
Crossref

Cancer Risks Associated With <i>BRCA1</i> and <i>BRCA2</i> Pathogenic Variants

Journal of Clinical Oncology
2022-05-10 | Journal article
DOI: 10.1200/jco.21.02112
Part of ISSN: 0732-183X
Part of ISSN: 1527-7755
Contributors: Shuai Li; Valentina Silvestri; Goska Leslie; Timothy Rebbeck; Susan Neuhausen; John Hopper; Henriette Roed Nielsen; Andrew Lee; Xin Yang; Lesley McGuffog et al.
Source: Self-asserted source
Muhammad Usman Rashid

An Outlook on the COVID-19 Infection Magnitude in Pakistan and Potential Factors Contributing to Low Mortality Rates

Annals of King Edward Medical University
2022-02-02 | Journal article
DOI: 10.21649/akemu.v27i4.4908
Part of ISSN: 2079-0694
Part of ISSN: 2079-7192
Contributors: Rizwan Ullah Khan; Sidra Mumtaz; Muhammad Usman Rashid; Naila Malkani
Source: Self-asserted source
Muhammad Usman Rashid

Epidemiological Assessment of Oral Cancer Burden in Pakistan

Cancer Investigation
2021-11-26 | Journal article
DOI: 10.1080/07357907.2021.1982962
Contributors: Naila Malkani; Sara Kazmi; Muhammad Usman Rashid
Source: check_circle
Crossref

Clinical Characteristics of COVID-19-Infected Cancer Patients in Pakistan: Differences Between Survivors and Non-Survivors.

Frontiers in oncology
2021-05-20 | Journal article
DOI: 10.3389/fonc.2021.655634
PMID: 34094950
PMC: PMC8173078
Contributors: Asghar K; Abu Bakar M; Akram MJ; Farooq A; Siddique K; Rana IA; Ali J; Rashid MU; Khan AA; Loya A
Source: Self-asserted source
Muhammad Usman Rashid

In-Silico Analyses of Nonsynonymous Variants in the BRCA1 Gene.

Biochemical genetics
2021-05-04 | Journal article
DOI: 10.1007/s10528-021-10074-7
PMID: 33945048
Contributors: Arshad S; Ishaque I; Mumtaz S; Rashid MU; Naila Malkani
Source: Self-asserted source
Muhammad Usman Rashid

SARS-COV-2 infection and lung tumor microenvironment

Molecular Biology Reports
2021-02-23 | Journal article
DOI: 10.1007/s11033-021-06149-8
Contributors: Naila Malkani; Muhammad Usman Rashid
Source: check_circle
Crossref

A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers.

Nature communications
2021-02-17 | Journal article
DOI: 10.1038/s41467-020-20496-3
PMID: 33597508
PMC: PMC7890067
Contributors: Coignard J; Lush M; Beesley J; Tracy O'Mara; Joe Dennis; Jonathan Tyrer; Daniel Barnes; McGuffog L; Goska Leslie; Bolla MK et al.
Source: Self-asserted source
Muhammad Usman Rashid

Breast Cancer Risk Factors and Survival by Tumor Subtype: Pooled Analyses from the Breast Cancer Association Consortium.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
2021-01-26 | Journal article
DOI: 10.1158/1055-9965.epi-20-0924
PMID: 33500318
PMC: PMC8026532
Contributors: Morra A; Jung AY; Sabine Behrens; Renske Keeman; Thomas Ahearn; Anton-Culver H; Volker Arndt; Annelie Augustinsson; Auvinen PK; Beane Freeman LE et al.
Source: Self-asserted source
Muhammad Usman Rashid

Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women.

The New England journal of medicine
2021-01-20 | Journal article
DOI: 10.1056/nejmoa1913948
PMID: 33471991
PMC: PMC7611105
Contributors: Breast Cancer Association Consortium; Dorling L; Carvalho S; Jamie Allen; González-Neira A; Luccarini C; Wahlström C; Pooley KA; Parsons MT; Fortuno C et al.
Source: Self-asserted source
Muhammad Usman Rashid

Prevalence of RECQL germline variants in Pakistani early-onset and familial breast cancer patients

Hereditary Cancer in Clinical Practice
2020-12 | Journal article
DOI: 10.1186/s13053-020-00159-6
Contributors: Muhammad Usman Rashid; Noor Muhammad; Faiz Ali Khan; Umara Shehzad; Humaira Naeemi; Naila Malkani; Ute Hamann
Source: check_circle
Crossref

Forkhead box P3 and indoleamine 2,3-dioxygenase co-expression in Pakistani triple negative breast cancer patients.

World journal of clinical oncology
2020-12-01 | Journal article
DOI: 10.5306/wjco.v11.i12.1018
PMID: 33437664
PMC: PMC7769718
Contributors: Asghar K; Loya A; Rana IA; Bakar MA; Farooq A; Tahseen M; Ishaq M; Masood I; Rashid MU
Source: Self-asserted source
Muhammad Usman Rashid

Characterization of the Cancer Spectrum in Men With Germline BRCA1 and BRCA2 Pathogenic Variants

JAMA Oncology
2020-07-02 | Journal article
DOI: 10.1001/jamaoncol.2020.2134
Part of ISSN: 2374-2437
Source: Self-asserted source
Muhammad Usman Rashid

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses.

Nature genetics
2020-05-18 | Journal article
DOI: 10.1038/s41588-020-0609-2
PMID: 32424353
PMC: PMC7808397
Contributors: Zhang H; Ahearn TU; Lecarpentier J; Daniel Barnes; Beesley J; Qi G; Jiang X; Tracy O'Mara; Zhao N; Bolla MK et al.
Source: Self-asserted source
Muhammad Usman Rashid

Transcriptome-wide association study of breast cancer risk by estrogen-receptor status.

Genetic epidemiology
2020-03-01 | Journal article
DOI: 10.1002/gepi.22288
PMID: 32115800
PMC: PMC7987299
Contributors: Feng H; Gusev A; Pasaniuc B; Wu L; Long J; Abu-Full Z; Aittomäki K; Andrulis IL; Anton-Culver H; Antoniou AC et al.
Source: Self-asserted source
Muhammad Usman Rashid

Prevalence and spectrum of MLH1, MSH2, and MSH6 pathogenic germline variants in Pakistani colorectal cancer patients

Hereditary Cancer in Clinical Practice
2019-12 | Journal article
DOI: 10.1186/s13053-019-0128-2
Contributors: Muhammad Usman Rashid; Humaira Naeemi; Noor Muhammad; Asif Loya; Jan Lubiński; Anna Jakubowska; Muhammed Aasim Yusuf
Source: check_circle
Crossref

Spectrum and prevalence of BRCA1/2 germline mutations in Pakistani breast cancer patients: results from a large comprehensive study

Hereditary Cancer in Clinical Practice
2019-12 | Journal article
DOI: 10.1186/s13053-019-0125-5
Part of ISSN: 1897-4287
Source: Self-asserted source
Muhammad Usman Rashid

The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

npj Breast Cancer
2019-12 | Journal article
DOI: 10.1038/s41523-019-0127-5
Part of ISSN: 2374-4677
Source: Self-asserted source
Muhammad Usman Rashid

Two truncating variants in FANCC and breast cancer risk

Scientific Reports
2019-12 | Journal article
DOI: 10.1038/s41598-019-48804-y
Part of ISSN: 2045-2322
Source: Self-asserted source
Muhammad Usman Rashid

Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness

Cancer Research
2019-11-13 | Journal article
DOI: 10.1158/0008-5472.can-19-1840
Part of ISSN: 0008-5472
Part of ISSN: 1538-7445
Source: Self-asserted source
Muhammad Usman Rashid

Association between Cyclooxygenase-2 and Indoleamine 2,3-Dioxygenase Expression in Breast Cancer Patients from Pakistan

Asian Pacific Journal of Cancer Prevention
2019-11-01 | Journal article
DOI: 10.31557/apjcp.2019.20.11.3521
Part of ISSN: 2476-762X
Source: Self-asserted source
Muhammad Usman Rashid

Absence of the TRIP13 c.1060C>T Mutation in Wilms Tumor Patients From Pakistan

Journal of Pediatric Hematology/Oncology
2019-09 | Journal article
DOI: 10.1097/mph.0000000000001602
Part of ISSN: 1077-4114
Source: Self-asserted source
Muhammad Usman Rashid

Prevalence of PALB2 Germline Mutations in Early-onset and Familial Breast/Ovarian Cancer Patients from Pakistan

Cancer Research and Treatment
2019-07-15 | Journal article
DOI: 10.4143/crt.2018.356
Part of ISSN: 1598-2998
Part of ISSN: 2005-9256
Source: Self-asserted source
Muhammad Usman Rashid

INHERITED GENETIC SUSCEPTIBILITY TO BREAST CANCER IN PAKISTAN

Journal of Cancer & Allied Specialties
2018-07-01 | Journal article
DOI: 10.37029/jcas.v4i2.179
Part of ISSN: 2411-989X
Source: Self-asserted source
Muhammad Usman Rashid

Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations

Human Mutation
2018-05 | Journal article
DOI: 10.1002/humu.23406
Part of ISSN: 1059-7794
Source: Self-asserted source
Muhammad Usman Rashid

Prevalence and Penetrance of BRCA1 and BRCA2 Germline Mutations in Colombian Breast Cancer Patients

Scientific Reports
2017-12 | Journal article
DOI: 10.1038/s41598-017-05056-y
Part of ISSN: 2045-2322
Source: Self-asserted source
Muhammad Usman Rashid

HOW TO WRITE A SCIENTIFIC RESEARCH PAPER

Journal of Cancer & Allied Specialties
2017-10-02 | Journal article
DOI: 10.37029/jcas.v3i3.135
Part of ISSN: 2411-989X
Source: Self-asserted source
Muhammad Usman Rashid

BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer

Cancer Research
2017-06-01 | Journal article
DOI: 10.1158/0008-5472.can-16-2568
Part of ISSN: 0008-5472
Part of ISSN: 1538-7445
Source: Self-asserted source
Muhammad Usman Rashid

Indoleamine 2,3-dioxygenase: As a potential prognostic marker and immunotherapeutic target for hepatocellular carcinoma.

World journal of gastroenterology
2017-04-01 | Journal article
DOI: 10.3748/wjg.v23.i13.2286
PMID: 28428708
PMC: PMC5385395
Source: Self-asserted source
Muhammad Usman Rashid

Contribution of BRCA1 large genomic rearrangements to early-onset and familial breast/ovarian cancer in Pakistan

Breast Cancer Research and Treatment
2017-01 | Journal article
DOI: 10.1007/s10549-016-4044-0
Part of ISSN: 0167-6806
Part of ISSN: 1573-7217
Source: Self-asserted source
Muhammad Usman Rashid

Nanomedicine and cancer immunotherapy: focus on indoleamine 2,3-dioxygenase inhibitors

OncoTargets and Therapy
2017-01 | Journal article
DOI: 10.2147/ott.s119362
Part of ISSN: 1178-6930
Source: Self-asserted source
Muhammad Usman Rashid

Current Status of the Management of Hereditary Breast and Ovarian Cancer in Asia: First Report by the Asian BRCA Consortium

Public Health Genomics
2016 | Journal article
DOI: 10.1159/000441714
Part of ISSN: 1662-4246
Part of ISSN: 1662-8063
Source: Self-asserted source
Muhammad Usman Rashid

A novel deleterious c.2656G>T MSH2 germline mutation in a Pakistani family with a phenotypic overlap of hereditary breast and ovarian cancer and Lynch syndrome

Hereditary Cancer in Clinical Practice
2016-12 | Journal article
DOI: 10.1186/s13053-016-0056-3
Part of ISSN: 1897-4287
Source: Self-asserted source
Muhammad Usman Rashid
grade
Preferred source (of 2)‎

High prevalence and predominance of BRCA1 germline mutations in Pakistani triple-negative breast cancer patients

BMC Cancer
2016-12 | Journal article
DOI: 10.1186/s12885-016-2698-y
Part of ISSN: 1471-2407
Source: Self-asserted source
Muhammad Usman Rashid
grade
Preferred source (of 2)‎

Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus

Breast Cancer Research
2016-12 | Journal article
DOI: 10.1186/s13058-016-0718-0
Part of ISSN: 1465-542X
Source: Self-asserted source
Muhammad Usman Rashid

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast–ovarian cancer susceptibility locus

Nature Communications
2016-11 | Journal article
DOI: 10.1038/ncomms12675
Part of ISSN: 2041-1723
Source: Self-asserted source
Muhammad Usman Rashid

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170

Nature Genetics
2016-04 | Journal article
DOI: 10.1038/ng.3521
Part of ISSN: 1061-4036
Part of ISSN: 1546-1718
Source: Self-asserted source
Muhammad Usman Rashid

Association between the BsmI Polymorphism in the Vitamin D Receptor Gene and Breast Cancer Risk: Results from a Pakistani Case-Control Study.

PloS one
2015-10-30 | Journal article
DOI: 10.1371/journal.pone.0141562
PMID: 26517870
PMC: PMC4627649
Source: Self-asserted source
Muhammad Usman Rashid

BRCA1genetic testing in a Pakistani breast-ovarian cancer family with multiple consanguineous marriages

Clinical Genetics
2015-08 | Journal article
DOI: 10.1111/cge.12533
Part of ISSN: 0009-9163
Source: Self-asserted source
Muhammad Usman Rashid

Absence of the FANCM c.5101C>T mutation in BRCA1/2-negative triple-negative breast cancer patients from Pakistan

Breast Cancer Research and Treatment
2015-07 | Journal article
DOI: 10.1007/s10549-015-3457-5
Part of ISSN: 0167-6806
Part of ISSN: 1573-7217
Source: Self-asserted source
Muhammad Usman Rashid

Association of Type and Location ofBRCA1andBRCA2Mutations With Risk of Breast and Ovarian Cancer

JAMA
2015-04-07 | Journal article
DOI: 10.1001/jama.2014.5985
Part of ISSN: 0098-7484
Source: Self-asserted source
Muhammad Usman Rashid
Items per page:
Page 1 of 2

Peer review (6 reviews for 1 publication/grant)

Review activity for Hereditary Cancer in Clinical Practice. (6)
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