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Other IDs

Scopus Author ID: 55387594400

Keywords

Bioconjugation, Drug Discovery, Drug Delivery

Countries

China

Activities

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Employment (2)

Georgia Institute of Technology: Atlanta, GA, US

2018-12-10 to present (Chemistry & Biochemistry)
Employment
Source: Self-asserted source
Minghao Xu

University of Utah: Salt Lake City, UT, US

2016-02-08 to 2018-11-30 | Postdoctoral Research Fellow (Medicinal Chemistry)
Employment
Source: Self-asserted source
Minghao Xu

Education and qualifications (1)

East China University of Science and Technology: Shanghai, Shanghai, CN

2010-09-01 to 2015-06-30 | Ph.D (College of Pharmacy)
Education
Source: Self-asserted source
Minghao Xu

Works (19)

Bioorthogonal chemistry

Nature Reviews Methods Primers
2021-04-15 | Journal article
DOI: 10.1038/s43586-021-00028-z
Contributors: Samuel L. Scinto; Didier A. Bilodeau; Robert Hincapie; Wankyu Lee; Sean S. Nguyen; Minghao Xu; Christopher W. am Ende; M. G. Finn; Kathrin Lang; Qing Lin et al.
Source: check_circle
Crossref

Isonitrile-responsive and bioorthogonally removable tetrazine protecting groups

Chemical Science
2020 | Journal article
DOI: 10.1039/C9SC04649F
Contributors: Julian Tu; Dennis Svatunek; Saba Parvez; Hannah J. Eckvahl; Minghao Xu; Randall T. Peterson; K. N. Houk; Raphael M. Franzini
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Enveloped Virus Inactivation on Personal Protective Equipment by Exposure to Ozone

2020-05-26 | Other
DOI: 10.1101/2020.05.23.20111435
Contributors: Emmeline L. Blanchard; Justin D. Lawrence; Jeffery A. Noble; Minghao Xu; Taekyu Joo; Nga Lee Ng; Britney E. Schmidt; Philip J. Santangelo; M.G. Finn
Source: check_circle
Crossref

Tuning Isonitrile/Tetrazine Chemistry for Accelerated Deprotection and Formation of Stable Conjugates

The Journal of Organic Chemistry
2019-12-06 | Journal article
DOI: 10.1021/acs.joc.9b02522
Contributors: Minghao Xu; Titas Deb; Julian Tu; Raphael M. Franzini
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Dissociative Bioorthogonal Reactions

ChemBioChem
2019-07 | Journal article
DOI: 10.1002/cbic.201800810
Contributors: Julian Tu; Minghao Xu; Raphael M. Franzini
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Bioorthogonal Removal of 3-Isocyanopropyl Groups Enables the Controlled Release of Fluorophores and Drugs in Vivo

Journal of the American Chemical Society
2018-07-11 | Journal article
DOI: 10.1021/jacs.8b05093
Contributors: Julian Tu; Minghao Xu; Saba Parvez; Randall T. Peterson; Raphael M. Franzini
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Dissociative reactions of benzonorbornadienes with tetrazines: scope of leaving groups and mechanistic insights

Organic & Biomolecular Chemistry
2017 | Journal article
DOI: 10.1039/C7OB02191G
Contributors: M. Xu; R. Galindo-Murillo; T. E. Cheatham; R. M. Franzini
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Rapid and efficient tetrazine-induced drug release from highly stable benzonorbornadiene derivatives

Chem. Commun.
2017 | Journal article
DOI: 10.1039/C7CC03477F
Source: Self-asserted source
Minghao Xu
grade
Preferred source (of 3)‎

Discovery and Rational Design of Natural-Product-Derived 2-Phenyl-3,4-dihydro-2H-benzo[f]chromen-3-amine Analogs as Novel and Potent Dipeptidyl Peptidase 4 (DPP-4) Inhibitors for the Treatment of Type 2 Diabetes

Journal of Medicinal Chemistry
2016-07-28 | Journal article
DOI: 10.1021/acs.jmedchem.6b00505
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Source: Self-asserted source
Minghao Xu
grade
Preferred source (of 2)‎

Design, Synthesis, X-ray Crystallographic Analysis, and Biological Evaluation of Thiazole Derivatives as Potent and Selective Inhibitors of Human Dihydroorotate Dehydrogenase

Journal of Medicinal Chemistry
2015 | Journal article
DOI: 10.1021/jm501127s
ARXIV:

http://dx.doi.org/10.1021/jm501127s

Source: Self-asserted source
Minghao Xu
grade
Preferred source (of 2)‎

Rational Design of Benzylidenehydrazinyl-Substituted Thiazole Derivatives as Potent Inhibitors of Human Dihydroorotate Dehydrogenase with in Vivo Anti-arthritic Activity

Scientific Reports
2015-12 | Journal article
DOI: 10.1038/srep14836
Part of ISSN: 2045-2322
Source: Self-asserted source
Minghao Xu
grade
Preferred source (of 2)‎

Novel Selective and Potent Inhibitors of Malaria Parasite Dihydroorotate Dehydrogenase: Discovery and Optimization of Dihydrothiophenone Derivatives

Journal of Medicinal Chemistry
2013 | Journal article
DOI: 10.1021/jm400938g
ARXIV:

http://dx.doi.org/10.1021/jm400938g

Source: Self-asserted source
Minghao Xu
grade
Preferred source (of 2)‎

Synthesis, activity evaluation, and docking analysis of barbituric acid aryl hydrazone derivatives as RSK2 inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry
2013-08 | Journal article
DOI: 10.3109/14756366.2012.681651
Part of ISSN: 1475-6366
Part of ISSN: 1475-6374
Source: Self-asserted source
Minghao Xu
grade
Preferred source (of 2)‎

Rationally Designed Multitarget Anticancer Agents

Current Medicinal Chemistry
2013-03-01 | Journal article
DOI: 10.2174/0929867311320130009
Part of ISSN: 0929-8673
Source: Self-asserted source
Minghao Xu
grade
Preferred source (of 2)‎

Discovery of Diverse Human Dihydroorotate Dehydrogenase Inhibitors as Immunosuppressive Agents by Structure-Based Virtual Screening

Journal of Medicinal Chemistry
2012 | Journal article
DOI: 10.1021/jm300630p
ARXIV:

http://dx.doi.org/10.1021/jm300630p

Source: Self-asserted source
Minghao Xu
grade
Preferred source (of 3)‎

Abstract 4772: Novel drug discovery approach targeting STAT3 for breast cancer therapy using MLSD and drug repositioning

Cancer Chemistry
2012-04-15 | Conference paper
DOI: 10.1158/1538-7445.am2012-4772
Source: Self-asserted source
Minghao Xu

Compound for Detecting Dihydroorotate Dehydrogenase

Patent
Source: Self-asserted source
Minghao Xu

Pentabasic Dihydrogen Heterocyclic Ketone Derivative as DHODH Inhibitor and Use Thereof

Patent
Source: Self-asserted source
Minghao Xu

Thiazole Derivative as DHODH Inhibitor and Use Thereof

Patent
Source: Self-asserted source
Minghao Xu

Peer review (3 reviews for 3 publications/grants)

Review activity for ChemBioChem. (1)
Review activity for Chemistry Central journal. (1)
Review activity for Molecules. (1)
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