Personal information

Other IDs

Scopus Author ID: 7402257323

Countries

United States

Activities

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Employment (5)

Autonomous Therapeutics: Rockville, MD, US

2022-09-01 to 2023-04-14 | Associate Director (Molecular Virology )
Employment
Source: Self-asserted source
Won-Bin Young

GlaxoSmithKline Research and Development Upper Providence: Collegeville, PA, US

2020-09-01 to 2022-08-31 | Scientific Investigator (Infectious Diseases)
Employment
Source: Self-asserted source
Won-Bin Young

Janssen Pharmaceuticals: Spring House, PA, US

2019-04-01 to 2020-08-31 | Immunologist II (Discovery Sciences)
Employment
Source: Self-asserted source
Won-Bin Young

Lewis Katz School of Medicine at Temple University: Philadelphia, PA, US

2017-02-15 to 2019-03-31 | Senior Research Associate (Neuroscience)
Employment
Source: Self-asserted source
Won-Bin Young

University of Pittsburgh School of Medicine: Pittsburgh, PA, US

2011-04-01 to 2016-12-31 | Assistant Professor (Radiology)
Employment
Source: Self-asserted source
Won-Bin Young

Education and qualifications (1)

Iowa State University: Ames, IA, US

PhD (Animal Science/Molecular, Cellular and Developmental Biology)
Education
Source: Self-asserted source
Won-Bin Young

Professional activities (3)

NIH: Bethesda, MD, US

2017-11 to 2017-11 | Grant Reviewer, Special Emphasis Panel, PAR-15-164, “HIV Vaccine Research and Design (HIVRAD) Program (P01) (NIAID)
Service
Source: Self-asserted source
Won-Bin Young

NIH: Bethesda, MD, US

2016-04 to 2016-04 | Grant Reviewer, NIH Special Emphasis Panel, RFA AI-16-028, “Understanding HIV Rebound”. (NIAID)
Service
Source: Self-asserted source
Won-Bin Young

NIH: Bethesda, MD, US

2014-11 to 2014-11 | Grant Reviewer, Special Emphasis Panel, PAR-14-206, “HIV Vaccine Research and Design (HIVRAD) Program (P01) (NIAID)
Service
Source: Self-asserted source
Won-Bin Young

Funding (4)

Identification of receptors for transcytotic delivery of therapeutic agents crossing

2016-07 to 2018-06 | Grant
National Institutes of Health (MD, MD, US)
GRANT_NUMBER:

R21NS094084
Source: Self-asserted source
Won-Bin Young

Development of Molecular Imaging Technology Visualizing Viral Reservoirs in Vivo

2013-04-08 to 2015-02-28 | Grant
National Institute of Mental Health (Rockville, US)
GRANT_NUMBER: 5R21MH100949-02
GRANT_NUMBER: 5R21MH100949-02
Source: Self-asserted source
Won-Bin Young via DimensionsWizard

IN VIVO VISUALIZATION AND QUANTIFICATION OF EPIGENETIC ACTIVITIES USING MAGNETIC

2010-09-17 to 2013-05-31 | Grant
National Institute on Drug Abuse (Rockville, US)
GRANT_NUMBER: 7R56DA030330-02
GRANT_NUMBER: 7R56DA030330-02
Source: Self-asserted source
Won-Bin Young via DimensionsWizard

Exon Boundary Tags (EBTs) for Human Functional Genome Annotation

2006-09-26 to 2007-03-31 | Grant
National Human Genome Research Institute (Bethesda, US)
GRANT_NUMBER: 1R43HG004180-01
GRANT_NUMBER: 1R43HG004180-01
Source: Self-asserted source
Won-Bin Young via DimensionsWizard

Works (20)

Methamphetamine facilitates HIV infection of primary human monocytes through inhibiting cellular viral restriction factors

Cell & Bioscience
2021-11-10 | Journal article
DOI: 10.1186/s13578-021-00703-4
Part of ISSN: 2045-3701
Contributors: Yu Liu; Feng-Zhen Meng; Xu Wang; Peng Wang; Jin-Biao Liu; Wen-Hui Hu; Won-Bin Young; Wenzhe Ho
Source: Self-asserted source
Won-Bin Young

Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice

Nature Communications
2019-07-02 | Journal article
DOI: 10.1038/s41467-019-10366-y
Part of ISSN: 2041-1723
Contributors: Prasanta K. Dash; Rafal Kaminski; Ramona Bella; Hang Su; Saumi Mathews; Taha M. Ahooyi; Chen Chen; Pietro Mancuso; Rahsan Sariyer; Pasquale Ferrante et al.
Source: Self-asserted source
Won-Bin Young

Removal of HIV DNA by CRISPR from Patient Blood Engrafts in Humanized Mice

Molecular Therapy - Nucleic Acids
2018-09 | Journal article
DOI: 10.1016/j.omtn.2018.05.021
Part of ISSN: 2162-2531
Contributors: Ramona Bella; Rafal Kaminski; Pietro Mancuso; Won-Bin Young; Chen Chen; Rahsan Sariyer; Tracy Fischer; Shohreh Amini; Pasquale Ferrante; Jeffrey M. Jacobson et al.
Source: Self-asserted source
Won-Bin Young
grade
Preferred source (of 2)‎

CRISPR Editing Technology in Biological and Biomedical Investigation

Journal of Cellular Biochemistry
2017-11 | Journal article
DOI: 10.1002/jcb.26099
Part of ISSN: 0730-2312
Part of ISSN: 1097-4644
Contributors: Martyn K. White; Rafal Kaminski; Won‐Bin Young; Pamela C. Roehm; Kamel Khalili
Source: Self-asserted source
Won-Bin Young

Specific and Stable Suppression of HIV Provirus Expression In Vitro by Chimeric Zinc Finger DNA Methyltransferase 1

Molecular Therapy - Nucleic Acids
2017-03 | Journal article
DOI: 10.1016/j.omtn.2017.01.002
Part of ISSN: 2162-2531
Contributors: Junxiao Deng; Xiying Qu; Panpan Lu; Xinyi Yang; Yuqi Zhu; Haiyan Ji; Yanan Wang; Zhengtao Jiang; Xian Li; Yangcheng Zhong et al.
Source: Self-asserted source
Won-Bin Young

Negative Feedback Regulation of HIV-1 by Gene Editing Strategy

Scientific Reports
2016-08-16 | Journal article
DOI: 10.1038/srep31527
Part of ISSN: 2045-2322
Contributors: Rafal Kaminski; Yilan Chen; Julian Salkind; Ramona Bella; Won-bin Young; Pasquale Ferrante; Jonathan Karn; Thomas Malcolm; Wenhui Hu; Kamel Khalili
Source: Self-asserted source
Won-Bin Young

Functional screening of guide RNAs targeting the regulatory and structural HIV-1 viral genome for a cure of AIDS

AIDS
2016-05-15 | Journal article
DOI: 10.1097/qad.0000000000001079
Part of ISSN: 0269-9370
Contributors: Chaoran Yin; Ting Zhang; Fang Li; Fan Yang; Raj Putatunda; Won-Bin Young; Kamel Khalili; Wenhui Hu; Yonggang Zhang
Source: Self-asserted source
Won-Bin Young
grade
Preferred source (of 2)‎

CRISPR/gRNA-directed synergistic activation mediator (SAM) induces specific, persistent and robust reactivation of the HIV-1 latent reservoirs

Scientific Reports
2015 | Journal article
DOI: 10.1038/srep16277
EID:

2-s2.0-84947078456
Contributors: Zhang, Y.; Yin, C.; Zhang, T.; Li, F.; Yang, W.; Kaminski, R.; Fagan, P.R.; Putatunda, R.; Young, W.-B.; Khalili, K. et al.
Source: Self-asserted source
Won-Bin Young via Scopus - Elsevier

Visualization and quantification of simian immunodeficiency virus-infected cells using non-invasive molecular imaging

Journal of General Virology
2015 | Journal article
DOI: 10.1099/jgv.0.000245
EID:

2-s2.0-84944768937
Contributors: Song, J.; Cai, Z.; White, A.G.; Jin, T.; Wang, X.; Kadayakkara, D.; Anderson, C.J.; Ambrose, Z.; Young, W.-B.
Source: Self-asserted source
Won-Bin Young via Scopus - Elsevier

U6 promoter-enhanced GlnUAG suppressor tRNA has higher suppression efficacy and can be stably expressed in 293 cells

2013 | Journal article
DOI: 10.1002/jgm.2696
EID:

2-s2.0-84874366833
Contributors: Koukuntla, R.; Ramsey, W.J.; Young, W.-B.; Link, C.J.
Source: Self-asserted source
Won-Bin Young via Scopus - Elsevier
grade
Preferred source (of 2)‎

Assaying macrophage activity in a murine model of inflammatory bowel disease using fluorine-19 MRI

2012 | Journal article
DOI: 10.1038/labinvest.2012.7
EID:

2-s2.0-84859346455
Contributors: Kadayakkara, D.K.; Ranganathan, S.; Young, W.-B.; Ahrens, E.T.
Source: Self-asserted source
Won-Bin Young via Scopus - Elsevier
grade
Preferred source (of 2)‎

Rapid quantification of inflammation in tissue samples using perfluorocarbon emulsion and fluorine-19 nuclear magnetic resonance

2011 | Journal article
DOI: 10.2144/000113652
EID:

2-s2.0-79955443368
Contributors: Ahrens, E.T.; Young, W.-B.; Xu, H.; Pusateri, L.K.
Source: Self-asserted source
Won-Bin Young via Scopus - Elsevier
grade
Preferred source (of 2)‎

In vivo observation of intracellular oximetry in perfluorocarbon-labeled glioma cells and chemotherapeutic response in the CNS using fluorine-19 MRI

2010 | Journal article
DOI: 10.1002/mrm.22506
EID:

2-s2.0-78349268301
Contributors: Kadayakkara, D.K.K.; Janjic, J.M.; Pusateri, L.K.; Young, W.-B.; Ahrens, E.T.
Source: Self-asserted source
Won-Bin Young via Scopus - Elsevier
grade
Preferred source (of 2)‎

Refinement of under-determined loops of Human Prion Protein by database-derived distance constraints

2009 | Journal article
DOI: 10.1504/IJDMB.2009.029206
EID:

2-s2.0-70549102056
Contributors: Cui, F.; Mukhopadhyay, K.; Young, W.-B.; Jernigan, R.L.; Wu, Z.
Source: Self-asserted source
Won-Bin Young via Scopus - Elsevier
grade
Preferred source (of 2)‎

Refinement of under-determined loops of human prion protein by database-derived distance constraints

2007 | Conference paper
DOI: 10.1109/BIBMW.2007.4425395
EID:

2-s2.0-44949096375
Contributors: Cui, F.; Mukhopadhyay, K.; Young, W.-B.; Jernigan, R.L.; Wu, Z.
Source: Self-asserted source
Won-Bin Young via Scopus - Elsevier
grade
Preferred source (of 2)‎

Transduction of hematopoietic stem cells with a retroviral vector expressing the neomycin phosphotransferase gene

2003 | Journal article
DOI: 10.1038/sj.bmt.1704178
EID:

2-s2.0-0041911473
Contributors: Link, C.J.; Seregina, T.; Edleman, M.; Young, W.-B.; Burt, R.K.; Kisselev, S.
Source: Self-asserted source
Won-Bin Young via Scopus - Elsevier
grade
Preferred source (of 2)‎

Chimeric retroviral helper virus and picornavirus IRES sequence to eliminate DNA methylation for improved retroviral packaging cells

2000 | Journal article
DOI: 10.1128/JVI.74.11.5242-5249.2000
EID:

2-s2.0-0034106197
Contributors: Young, W.-B.; Link Jr., C.J.
Source: Self-asserted source
Won-Bin Young via Scopus - Elsevier
grade
Preferred source (of 2)‎

DNA methylation of helper virus increases genetic instability of retroviral vector producer cells

2000 | Journal article
DOI: 10.1128/JVI.74.7.3177-3187.2000
EID:

2-s2.0-0034099093
Contributors: Young, W.-B.; Lindberg, G.L.; Link Jr., C.J.
Source: Self-asserted source
Won-Bin Young via Scopus - Elsevier
grade
Preferred source (of 2)‎

Restriction mapping of retroviral vector episomal DNA

2000 | Journal article
EID:

2-s2.0-0034097224
Contributors: Young, W.-B.; Beecham, E.J.; Lindberg, G.L.; Link Jr., C.L.
Source: Self-asserted source
Won-Bin Young via Scopus - Elsevier
grade
Preferred source (of 2)‎

A novel herpesvirus amplicon system for in vivo gene delivery

1997 | Journal article
EID:

2-s2.0-0030733144
Contributors: Wang, S.; Di, S.; Young, W.-B.; Jacobson, C.; Link Jr., C.J.
Source: Self-asserted source
Won-Bin Young via Scopus - Elsevier
grade
Preferred source (of 2)‎
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