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Scopus Author ID: 57203657257
Loop profile: 1405732

Keywords

membrane protein, molecular modelling, molecular dynamics, membrane transport

Countries

Germany

Activities

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Employment (4)

Ruhr-Universität Bochum: Bochum, Nordrhein-Westfalen, DE

(Arbeitsgruppe Molecular Simulation)
Employment
Source: check_circle
Ruhr-Universität Bochum

Ruhr University Bochum: Bochum, Nordrhein-Westfalen, DE

2020-06-01 to present | Research Associate (Theoretical Chemistry)
Employment
Source: Self-asserted source
Dario De Vecchis

University of Leeds: Leeds, West Yorkshire, GB

2017-10-02 to 2019-10-31 | Research Associate (Leeds Institute of Cardiovascular and Metabolic Medicine)
Employment
Source: Self-asserted source
Dario De Vecchis

CNRS Délégation Paris B: Paris, Île-de-France, FR

2017-02-01 to 2017-02-28 | Research Associate (Institute of Physico-Chemical Biology IBPC)
Employment
Source: Self-asserted source
Dario De Vecchis

Education and qualifications (3)

Paris Diderot University: Paris, FR

2013-11-01 to 2017-01-26 | PhD (Institute of Physico-Chemical Biology IBPC)
Education
Source: Self-asserted source
Dario De Vecchis

University of Rome Tor Vergata: Rome, Lazio, IT

2009-09-01 to 2013-07-25 | M.Sc in Bioinformatic (Structural Bioinformatics Lab)
Education
Source: Self-asserted source
Dario De Vecchis

University of Rome Tor Vergata: Rome, Lazio, IT

2005-09-01 to 2009-05-20 | B.Sc in Cellular and Molecular Biology
Education
Source: Self-asserted source
Dario De Vecchis

Professional activities (6)

German Biophysical Society: Bochum, DE

2022 to present
Membership
Source: Self-asserted source
Dario De Vecchis

Workshop “Computer Simulations and Theory of Macromolecules”: Hünfeld, DE

2024-02-01 | 1st Poster Price
Distinction
Source: Self-asserted source
Dario De Vecchis

European Commission: Brussels, BE

2024 | Seal of Excellence Marie Skłodowska-Curie Action. Postdoctoral Fellowship
Distinction
Source: Self-asserted source
Dario De Vecchis

FEBS: Cambridge, GB

2023-03 | Young Investigator Award - Talk Award (9th FEBS ABC2023 Special Meeting)
Distinction
Source: Self-asserted source
Dario De Vecchis

University of Leeds: Leeds, West Yorkshire, GB

2019-11-01 to 2022 | Visiting Research Fellow (Leeds Institute of Cardiovascular and Metabolic Medicine)
Invited position
Source: Self-asserted source
Dario De Vecchis

EMBO: Virtual, DE

2021-10-21 | Honourable mention poster price - Advances and Challenges in Biomolecular Simulations
Distinction
Source: Self-asserted source
Dario De Vecchis

Works (15)

Coupling the role of lipids to the conformational dynamics of the ABC transporter P-glycoprotein

Biophysical Journal
2024-08 | Journal article
DOI: 10.1016/j.bpj.2024.06.020
Part of ISSN: 0006-3495
Contributors: Dario De Vecchis; Lars V. Schäfer
Source: Self-asserted source
Dario De Vecchis

Structural basis for triacylglyceride extraction from mycobacterial inner membrane by MFS transporter Rv1410

Nature Communications
2023-10-13 | Journal article
DOI: 10.1038/s41467-023-42073-0
Part of ISSN: 2041-1723
Contributors: Sille Remm; Dario De Vecchis; Jendrik Schöppe; Cedric A. J. Hutter; Imre Gonda; Michael Hohl; Simon Newstead; Lars Schäfer; Markus Seeger
Source: Self-asserted source
Dario De Vecchis

Anionic Phospholipids Stimulate the Proton Pumping Activity of the Plant Plasma Membrane P-Type H+-ATPase

International Journal of Molecular Sciences
2023-08-23 | Journal article | Author
DOI: 10.3390/ijms241713106
Part of ISSN: 1422-0067
Contributors: Laura Charlotte Paweletz; Simon L. Holtbrügge; Malina Löb; Dario De Vecchis; Lars Schäfer; Thomas Günther-Pomorski; Bo Højen Justesen
Source: Self-asserted source
Dario De Vecchis

The ABC transporter MsbA adopts the wide inward-open conformation in E. coli cells

Science Advances
2022-10-14 | Journal article
DOI: 10.1126/sciadv.abn6845
Contributors: Laura Galazzo; Gianmarco Meier; Dovile Januliene; Kristian Parey; Dario De Vecchis; Bianca Striednig; Hubert Hilbi; Lars V. Schäfer; Ilya Kuprov; Arne Moeller et al.
Source: check_circle
Crossref

Modeling of full-length Piezo1 suggests importance of the proximal N-terminus for dome structure

Biophysical Journal
2021-04 | Journal article
DOI: 10.1016/j.bpj.2021.02.003
Contributors: Jiehan Chong; Dario De Vecchis; Adam J. Hyman; Oleksandr V. Povstyan; Melanie J. Ludlow; Jian Shi; David J. Beech; Antreas C. Kalli
Source: check_circle
Crossref

Molecular dynamics simulations of Piezo1 channel opening by increases in membrane tension

Biophysical Journal
2021-04 | Journal article
DOI: 10.1016/j.bpj.2021.02.006
Contributors: Dario De Vecchis; David J. Beech; Antreas C. Kalli
Source: check_circle
Crossref

Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 Channels

Cell Reports
2020-10 | Journal article
DOI: 10.1016/j.celrep.2020.108225
Part of ISSN: 2211-1247
Contributors: Jian Shi; Adam J. Hyman; Dario De Vecchis; Jiehan Chong; Laeticia Lichtenstein; T. Simon Futers; Myriam Rouahi; Anne Negre Salvayre; Nathalie Auge; Antreas C. Kalli et al.
Source: Self-asserted source
Dario De Vecchis

RBCs prevent rapid PIEZO1 inactivation and expose slow deactivation as a mechanism of dehydrated hereditary stomatocytosis

Blood
2020-07-02 | Journal article
DOI: 10.1182/blood.2019004174
Contributors: Elizabeth L. Evans; Oleksandr V. Povstyan; Dario De Vecchis; Fraser Macrae; Laeticia Lichtenstein; T. Simon Futers; Gregory Parsonage; Neil E. Humphreys; Antony Adamson; Antreas C. Kalli et al.
Source: check_circle
Crossref

Genetic variants of PIEZO1 associate with COVID-19 fatality

2020-06-03 | Other
DOI: 10.1101/2020.06.01.20119651
Contributors: C.W. Cheng; V. Deivasikamani; M.J. Ludlow; D. De Vecchis; A.C. Kalli; D.J. Beech; P. Sukumar
Source: check_circle
Crossref

A Molecular Perspective on Mitochondrial Membrane Fusion: From the Key Players to Oligomerization and Tethering of Mitofusin

The Journal of Membrane Biology
2019-09-04 | Journal article
DOI: 10.1007/s00232-019-00089-y
Part of ISSN: 0022-2631
Part of ISSN: 1432-1424
Source: Self-asserted source
Dario De Vecchis

Molecular simulations of intact Anion Exchanger 1 reveal specific domain and lipid interactions

Biophysical Journal
2019-08 | Journal article
DOI: 10.1016/j.bpj.2019.08.029
Part of ISSN: 0006-3495
Source: Self-asserted source
Dario De Vecchis

Structural dataset from microsecond-long simulations of yeast mitofusin Fzo1 in the context of membrane docking

Data in Brief
2019-08 | Journal article
DOI: 10.1016/j.dib.2019.104460
Part of ISSN: 2352-3409
Source: Self-asserted source
Dario De Vecchis

Physics-based oligomeric models of the yeast mitofusin Fzo1 at the molecular scale in the context of membrane docking

Mitochondrion
2019-07 | Journal article
DOI: 10.1016/j.mito.2019.06.010
Part of ISSN: 1567-7249
Source: Self-asserted source
Dario De Vecchis

A membrane-inserted structural model of the yeast mitofusin Fzo1

Scientific Reports
2017 | Journal article
DOI: 10.1038/s41598-017-10687-2
EID:

2-s2.0-85046477232

Part of ISBN:

20452322
Contributors: De Vecchis, D.; Cavellini, L.; Baaden, M.; Hénin, J.; Cohen, M.M.; Taly, A.
Source: Self-asserted source
Dario De Vecchis via Scopus - Elsevier

Gaining insights into mitochondrial membrane fusion through a structural and dynamic atomistic model of the mitofusin Fzo1p

Paris Diderot University
2017-01-26 | Dissertation or Thesis
Source: Self-asserted source
Dario De Vecchis

Peer review (6 reviews for 4 publications/grants)

Review activity for Biophysical journal. (2)
Review activity for Computational and Structural Biotechnology Journal (1)
Review activity for Data in brief. (2)
Review activity for The journal of physical chemistry. (1)
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