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Epigenetics, Genomic Imprinting, Glioma, DNA methylation, Histone modifications, Chromatin looping
France

Activities

Employment (3)

CNRS Délégation Rhône-Auvergne: Clermont-Ferrand, Auvergne, FR

2012-01-01 to present | Team leader (GReD (Génétique Reproduction and Development) )
Employment
Source: Self-asserted source
Philippe arnaud

CNRS Délégation Languedoc-Roussillon: Montpellier, Languedoc-Roussillon, FR

2003-01-01 to 2011-12-31 | Researcher (IGMM CNRS UMR5535)
Employment
Source: Self-asserted source
Philippe arnaud

Babraham Institute: Cambridge, Cambridgeshire, GB

2000-10-01 to 2003-12-31 | Post-Doc (Developmental Genetics)
Employment
Source: Self-asserted source
Philippe arnaud

Education and qualifications (1)

Université Blaise Pascal: Clermont-Ferrand, Auvergne, FR

1996-01-10 to 2000-09-10 | PhD (Biomove (Biologie Moléculaire des Végétaux Supérieurs))
Education
Source: Self-asserted source
Philippe arnaud

Works (50 of 71)

Items per page:
Page 1 of 2

Non-canonical imprinting, manifesting as post-fertilization placenta-specific parent-of-origin dependent methylation, is not conserved in humans

Human Molecular Genetics
2025-03-20 | Journal article
Contributors: Dagne Daskeviciute; Louise Chappell-Maor; Becky Sainty; Philippe Arnaud; Isabel Iglesias-Platas; Carlos Simon; Hiroaki Okae; Takahiro Arima; Rita Vassena; Jon Lartey et al.
Source: check_circle
Crossref

Biallelic non-productive enhancer-promoter interactions precede imprinted expression of Kcnk9 during mouse neural commitment

Human Genetics and Genomics Advances
2024 | Journal article
Contributors: Rojas, Cecilia Rengifo; Cercy, Jil; Perillous, Sophie; Gonthier-Gueret, Celine; Montibus, Bertille; Maupetit-Mehouas, Stephanie; Espinadel, Astrid; Dupre, Marylou; Hong, Charles C.; Hata, Kenichiro et al.
Source: check_circle
Web of Science Researcher Profile Sync

Biallelic non-productive enhancer-promoter interaction precedes imprinted expression of <italic>Kcnk9</italic> during mouse neural commitment

BioRxiv
2023 | Journal article
Contributors: Rojas, Cecilia Rengifo; Cercy, Jil; Perillous, Sophie; Gonthier-Gueret, Celine; Montibus, Bertille; Maupetit-Mehouas, Stephanie; Espinadel, Astrid; Dupre, Marylou; Hong, Charles C.; Hata, Kenichiro et al.
Source: check_circle
Web of Science Researcher Profile Sync

Variable allelic expression of imprinted genes at the <i>Peg13</i>, <i>Trappc9</i>, <i>Ago2</i> cluster in single neural cells.

Frontiers in cell and developmental biology
2022-10-12 | Journal article
Contributors: Claxton M; Pulix M; Seah MKY; Bernardo R; Zhou P; Aljuraysi S; Triantafillos Liloglou; Arnaud P; Kelsey G; Messerschmidt DM et al.
Source: Self-asserted source
Philippe arnaud
grade
Preferred source (of 2)‎

The Long Non-Coding RNA <i>HOXA-AS2</i> Promotes Proliferation of Glioma Stem Cells and Modulates Their Inflammation Pathway Mainly through Post-Transcriptional Regulation

International Journal of Molecular Sciences
2022-04 | Journal article | Author
Contributors: Elisa Le Boiteux; Pierre-Olivier Guichet; Konstantin Masliantsev; Bertille Montibus; Catherine Vaurs-Barriere; Céline Gonthier-Gueret; Emmanuel Chautard; Pierre Verrelle; Lucie Karayan-Tapon; Anne Fogli et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

L1 chimeric transcripts are expressed in healthy brain and their deregulation in glioma follows that of their host locus.

Human molecular genetics
2022-03-17 | Journal article
Source: Self-asserted source
Philippe arnaud
grade
Preferred source (of 2)‎

Widespread overexpression from the four DNA hypermethylated HOX clusters in aggressive (IDHwt) glioma is associated with H3K27me3 depletion and alternative promoter usage

Molecular Oncology
2021-03-15 | Journal article
Contributors: Elisa Le Boiteux; Franck Court; Pierre‐olivier Guichet; Catherine Vaurs-Barrière; Isabelle Vaillant; Emmanuel Chautard; Pierre Verrelle; Bruno M Costa; Lucie Karayan-Tapon; Anne Fogli et al.
Source: Self-asserted source
Philippe arnaud via HAL
grade
Preferred source (of 2)‎

HOX gene cluster (de)regulation in brain: from neurodevelopment to malignant glial tumours

Cellular and Molecular Life Sciences
2020-10-01 | Journal article
Contributors: Céline S. Gonçalves; Elisa Le Boiteux; Philippe Arnaud; Bruno M. Costa
Source: check_circle
Crossref

TET3 controls the expression of the H3K27me3 demethylase Kdm6b during neural commitment

Cellular and Molecular Life Sciences
2020-05-14 | Journal article
Part of ISSN: 1420-682X
Part of ISSN: 1420-9071
Source: Self-asserted source
Philippe arnaud

Transcriptional alterations in glioma result primarily from DNA methylation-independent mechanisms.

Genome research
2019-09-18 | Journal article
Source: Self-asserted source
Philippe arnaud

Most of transcriptional alterations in glioma result from DNA-methylation independent mechanisms: supplementary data

2019-01-11 | Other
Contributors: Philippe Arnaud; Franck Court; Elisa Le Boiteux; Anne Fogli; Mélanie Müller-Barthélémy; Catherine Vaurs-Barriére; Emmanuel Chautard; Bruno Pereira; Julian Biau; Jean-Louis Kemeny et al.
Source: check_circle
Crossref

An annotated list of bivalent chromatin regions in human ES cells: a new tool for cancer epigenetic research

ArXiv
2018 | Journal article
Contributors: Court, Franck; Arnaud, Philippe
Source: check_circle
Web of Science Researcher Profile Sync

Imprinting control regions (ICRs) are marked by mono-allelic bivalent chromatin when transcriptionally inactive

ArXiv
2018 | Journal article
Contributors: Maupetit-Méhouas, Stéphanie; Montibus, Bertille; Nury, David; Tayama, Chiharu; Wassef, Michel; Kota, Satya; Fogli, Anne; Campos, Fabiana Cerqueira; Hata, Kenichiro; Feil, Robert et al.
Source: check_circle
Web of Science Researcher Profile Sync

The long non-coding RNA HOTAIR is transcriptionally activated by HOXA9 and is an independent prognostic marker in patients with malignant glioma

ArXiv
2018 | Journal article
Contributors: Xavier-Magalhães, Ana; Gonçalves, Céline; Fogli, Anne; Lourenço, Tatiana; Pojo, Marta; Pereira, Bruno; Rocha, Miguel; Lopes, Maria; Crespo, Inês; Rebelo, Olinda et al.
Source: check_circle
Web of Science Researcher Profile Sync

DNA methylation profiling reveals a pathological signature that contributes to transcriptional defects of CD34+ CD15- cells in early chronic-phase chronic myeloid leukemia.

Molecular oncology
2018-03 | Journal article
Contributors: Maupetit-Mehouas S; Court F; Bourgne C; Guerci-Bresler A; Cony-Makhoul P; Johnson H; Etienne G; Rousselot P; Guyotat D; Janel A et al.
Source: Self-asserted source
Philippe arnaud via Europe PubMed Central

The long non-coding RNA HOTAIR is transcriptionally activated by HOXA9 and is an independent prognostic marker in patients with malignant glioma.

Oncotarget
2018-03 | Journal article
Contributors: Xavier-Magalhães A; Gonçalves CS; Fogli A; Lourenço T; Pojo M; Pereira B; Rocha M; Lopes MC; Crespo I; Rebelo O et al.
Source: Self-asserted source
Philippe arnaud via Europe PubMed Central

CLIFinder: identification of LINE-1 chimeric transcripts in RNA-seq data.

Bioinformatics (Oxford, England)
2018-02 | Journal article
Contributors: Pinson ME; Pogorelcnik R; Court F; Arnaud P; Vaurs-Barrière C
Source: Self-asserted source
Philippe arnaud via Europe PubMed Central

An annotated list of bivalent chromatin regions in human ES cells: a new tool for cancer epigenetic research

Oncotarget
2017 | Journal article
Contributors: Franck Court; Philippe P. Arnaud
Source: Self-asserted source
Philippe arnaud via HAL

Detection of the alternative lengthening of telomeres pathway in malignant gliomas for improved molecular diagnosis.

Journal of neuro-oncology
2017-07 | Journal article
Source: Self-asserted source
Philippe arnaud via Europe PubMed Central

An annotated list of bivalent chromatin regions in human ES cells: a new tool for cancer epigenetic research.

2016-12 | Journal article
Contributors: Court F; Arnaud P
Source: Self-asserted source
Philippe arnaud via Europe PubMed Central

In Vitro Corticogenesis from Embryonic Stem Cells Recapitulates the In Vivo Epigenetic Control of Imprinted Gene Expression.

2016-04 | Journal article
Contributors: Bouschet T; Dubois E; Reynès C; Kota SK; Rialle S; Maupetit-Méhouas S; Pezet M; Le Digarcher A; Nidelet S; Demolombe V et al.
Source: Self-asserted source
Philippe arnaud via Europe PubMed Central

The tumoral A genotype of the MGMT rs34180180 single-nucleotide polymorphism in aggressive gliomas is associated with shorter patients' survival.

2016-02 | Journal article
Contributors: Fogli A; Chautard E; Vaurs-Barrière C; Pereira B; Müller-Barthélémy M; Court F; Biau J; Pinto AA; Kémény JL; Khalil T et al.
Source: Self-asserted source
Philippe arnaud via Europe PubMed Central

Imprinting control regions (ICRs) are marked by mono-allelic bivalent chromatin when transcriptionally inactive.

Nucleic acids research
2016-01 | Journal article
Source: Self-asserted source
Philippe arnaud via Europe PubMed Central

Deep sequencing and de novo assembly of the mouse oocyte transcriptome define the contribution of transcription to the DNA methylation landscape.

Genome biology
2015-09 | Journal article
Source: Self-asserted source
Philippe arnaud via Europe PubMed Central

ICR noncoding RNA expression controls imprinting and DNA replication at the Dlk1-Dio3 domain

Developmental cell
2014 | Journal article
WOSUID:

WOS:000343195200005

Contributors: Kota, Satya K; Ll{\`e}res, David; Bouschet, Tristan; Hirasawa, Ryutaro; Marchand, Alice; Begon-Pescia, Christina; Sanli, Ildem; Arnaud, Philippe; Journot, Laurent; Girardot, Michael et al.
Source: Self-asserted source
Philippe arnaud via ResearcherID

Epigenetic Reprogramming in the Mammalian Germline

Epigenetics and Complex Traits
2013 | Book chapter
SOURCE-WORK-ID:

1203151100317-12

Contributors: Maupetit-M{\'e}houas, St{\'e}phanie; Nury, David; Arnaud, Philippe
Source: Self-asserted source
Philippe arnaud via ResearcherID

Liver x receptors protect from development of prostatic intra-epithelial neoplasia in mice

2013 | Journal article
WOSUID:

WOS:000320030000008

Contributors: Pommier, Aur{\'e}lien JC; Dufour, Julie; Alves, Georges; Viennois, Emilie; De Boussac, Hugues; Trousson, Amalia; Volle, David H; Caira, Fran{\c{c}}oise; Val, Pierre; Arnaud, Philippe et al.
Source: Self-asserted source
Philippe arnaud via ResearcherID

Characterization of novel paternal ncRNAs at the Plagl1 locus, including Hymai, predicted to interact with regulators of active chromatin.

PloS one
2012 | Journal article
Source: Self-asserted source
Philippe arnaud via Europe PubMed Central

Transcription and histone methylation changes correlate with imprint acquisition in male germ cells

The EMBO journal
2012 | Journal article
WOSUID:

WOS:000300871700010

Contributors: Henckel, Amandine; Chebli, Karim; Kota, Satya K; Arnaud, Philippe; Feil, Robert
Source: Self-asserted source
Philippe arnaud via ResearcherID

Synergic reprogramming of mammalian cells by combined exposure to mitotic Xenopus egg extracts and transcription factors

Proceedings of the National Academy of Sciences
2011 | Journal article
WOSUID:

WOS:000295975300027

Contributors: Ganier, Olivier; Bocquet, St{\'e}phane; Peiffer, Isabelle; Brochard, Vincent; Arnaud, Philippe; Puy, Aurore; Jouneau, Alice; Feil, Robert; Renard, Jean-Paul; M{\'e}chali, Marcel
Source: Self-asserted source
Philippe arnaud via ResearcherID

Human imprinted retrogenes exhibit non-canonical imprint chromatin signatures and reside in non-imprinted host genes.

Nucleic acids research
2011-06 | Journal article
Source: Self-asserted source
Philippe arnaud via Europe PubMed Central

Genomic imprinting in germ cells: imprints are under control

Reproduction
2010 | Journal article
WOSUID:

WOS:000281375200007

Contributors: Arnaud, Philippe
Source: Self-asserted source
Philippe arnaud via ResearcherID

Ring1B and Suv39h1 delineate distinct chromatin states at bivalent genes during early mouse lineage commitment

Development
2010 | Journal article
WOSUID:

WOS:000279828300005

Contributors: Alder, Olivia; Lavial, Fabrice; Helness, Anne; Brookes, Emily; Pinho, Sandra; Chandrashekran, Anil; Arnaud, Philippe; Pombo, Ana; O'Neill, Laura; Azuara, V{\'e}ronique
Source: Self-asserted source
Philippe arnaud via ResearcherID

Genome-wide identification of new imprinted genes.

Briefings in functional genomics
2010-07 | Journal article
Source: Self-asserted source
Philippe arnaud via Europe PubMed Central

Histone methylation is mechanistically linked to DNA methylation at imprinting control regions in mammals

Human molecular genetics
2009 | Journal article
WOSUID:

WOS:000269203000003

Contributors: Henckel, Amandine; Nakabayashi, Kazuhiko; Sanz, Lionel A; Feil, Robert; Hata, Kenichiro; Arnaud, Philippe
Source: Self-asserted source
Philippe arnaud via ResearcherID

Reciprocal imprinting of human GRB10 in placental trophoblast and brain: evolutionary conservation of reversed allelic expression

Human molecular genetics
2009 | Journal article
WOSUID:

WOS:000268330900012

Contributors: Monk, David; Arnaud, Philippe; Frost, Jennifer; Hills, Frank A; Stanier, Philip; Feil, Robert; Moore, Gudrun E
Source: Self-asserted source
Philippe arnaud via ResearcherID

A mono-allelic bivalent chromatin domain controls tissue-specific imprinting at Grb10

The EMBO journal
2008 | Journal article
WOSUID:

WOS:000259891300006

Contributors: Sanz, Lionel A; Chamberlain, Stormy; Sabourin, Jean-Charles; Henckel, Amandine; Magnuson, Terry; Hugnot, Jean-Philippe; Feil, Robert; Arnaud, Philippe
Source: Self-asserted source
Philippe arnaud via ResearcherID

Comparative analysis of human chromosome 7q21 and mouse proximal chromosome 6 reveals a placental-specific imprinted gene, TFPI2/Tfpi2, which requires EHMT2 and EED for allelic-silencing

Genome research
2008 | Journal article
WOSUID:

WOS:000258116100008

Contributors: Monk, David; Wagschal, Alexandre; Arnaud, Philippe; M{\&quot; u}ller, Pari-Sima; Parker-Katiraee, Layla; Bourc’his, D{\'e}borah; Scherer, Stephen W; Feil, Robert; Stanier, Philip et al.
Source: Self-asserted source
Philippe arnaud via ResearcherID

Evolutionary comparison of epigenetic profiles at large imprinted domains reveal differing mechanisms of allelic silencing

2008 | Journal article
WOSUID:

WOS:000255341800008

Contributors: Monk, David; Wagschal, A; Arnaud, P; Iglelias-Platas, I; Muller, P; Parker-Katiraee, L; Bourc'his, D; Scherer, SW; Stanier, P; Moore, GE
Source: Self-asserted source
Philippe arnaud via ResearcherID

Analysis of H19 and MEST/PEG1 and Line 1 transposon methylation patterns in oligozoospermia

Human Reproduction
2007 | Conference paper
WOSUID:

WOS:000255322200514

Contributors: Carvalho, F; Marques, CJ; Costa, P; Vaz, B; Fernandes, S; Arnaud, P; Barros, A; Sousa, M
Source: Self-asserted source
Philippe arnaud via ResearcherID

Chromatin Immunoprecipitation (ChIP) on Unfixed Chromatin from Cells and Tissues to Analyze Histone Modifications.

CSH protocols
2007 | Journal article
Source: Self-asserted source
Philippe arnaud via Europe PubMed Central

Early mouse embryo development: could epigenetics influence cell fate determination?

Bioessays
2007 | Journal article
SOURCE-WORK-ID:

1203151100320-11

Contributors: Henckel, Amandine; T{\'o}th, Szabolcs; Arnaud, Philippe
Source: Self-asserted source
Philippe arnaud via ResearcherID

Identification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolution

2007 | Journal article
WOSUID:

WOS:000247573900003

Contributors: Parker-Katiraee, Layla; Carson, Andrew R; Yamada, Takahiro; Arnaud, Philippe; Feil, Robert; Abu-Amero, Sayeda N; Moore, Gudrun E; Kaneda, Masahiro; Perry, George H; Stone, Anne C et al.
Source: Self-asserted source
Philippe arnaud via ResearcherID

PCR-Based Analysis of Immunoprecipitated Chromatin.

CSH protocols
2007 | Journal article
Source: Self-asserted source
Philippe arnaud via Europe PubMed Central

Early mouse embryo development: could epigenetics influence cell fate determination?

BioEssays : news and reviews in molecular, cellular and developmental biology
2007-06 | Journal article
Source: Self-asserted source
Philippe arnaud via Europe PubMed Central

Dynamics of placental imprinting: a comparison between mouse and humans

2006 | Journal article
WOSUID:

WOS:000241959200016

Contributors: Monk, David; Arnaud, Philippe; Apostolidou, Sophia; Kelsey, Gavin; Stanier, Philip; Feil, Robert; Moore, GE
Source: Self-asserted source
Philippe arnaud via ResearcherID

Imprinting of IGF2 P0 transcript and novel alternatively spliced INS-IGF2 isoforms show differences between mouse and human

Human molecular genetics
2006 | Journal article
WOSUID:

WOS:000236613300002

Contributors: Monk, David; Sanches, R; Arnaud, Philippe; Apostolidou, S; Hills, FA; Abu-Amero, S; Murrell, A; Friess, H; Reik, W; Stanier, Philip et al.
Source: Self-asserted source
Philippe arnaud via ResearcherID

Limited evolutionary conservation of imprinting in the human placenta

Proceedings of the National Academy of Sciences
2006 | Journal article
WOSUID:

WOS:000237151000038

Contributors: Monk, D; Arnaud, P; Apostolidou, S; Hills, FA; Kelsey, G; Stanier, P; Feil, R; Moore, GE
Source: Self-asserted source
Philippe arnaud via ResearcherID

MEDEA takes control of its own imprinting.

Cell
2006-02 | Journal article
Source: Self-asserted source
Philippe arnaud via Europe PubMed Central

Stochastic imprinting in the progeny of Dnmt3L-/- females.

Human molecular genetics
2006-02 | Journal article
Source: Self-asserted source
Philippe arnaud via Europe PubMed Central
Items per page:
Page 1 of 2

Peer review (8 reviews for 6 publications/grants)

Review activity for BMC biology. (1)
Review activity for Molecular biology and evolution. (1)
Review activity for Molecular oncology. (2)
Review activity for Nature communications (1)
Review activity for Nucleic acids research. (2)
Review activity for OBM genetics. (1)