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Employment (4)

University of the Basque Country: Leioa, ES

2014-11-01 to present | Ikerbasque Researcher, Senior Researcher (Neuroscience)
Employment
Source: Self-asserted source
Estibaliz Capetillo-Zarate

Ikerbasque, Basque Foundation for Science: Bilbao, ES

2014-11-01 to present
Employment
Source: Self-asserted source
Estibaliz Capetillo-Zarate

Achucarro Basque Center for Neuroscience: Leioa, ES

2014-11-01 to present | Ikerbasque Researcher, Senior Researcher
Employment
Source: Self-asserted source
Estibaliz Capetillo-Zarate

Weill Cornell Medical College: NY, NY, US

2014-09-01 to present | Adjunct Assistant Professor (Biochemistry)
Employment
Source: Self-asserted source
Estibaliz Capetillo-Zarate

Education and qualifications (3)

Rheinische Friedrich-Wilhelms-Universität Bonn: Bonn, Nordrhein-Westfalen, DE

2003 to 2006 | Doctor in Natural Science
Education
Source: Self-asserted source
Estibaliz Capetillo-Zarate

Sheffield Hallam University: Sheffield, South Yorkshire, GB

2001 to 2002 | Master of Science (Human Neurobiology)
Education
Source: Self-asserted source
Estibaliz Capetillo-Zarate

Universidad Complutense de Madrid: Madrid, Comunidad de Madrid, ES

1996 to 2001 | Bachelor in Biology (Neurobiology)
Education
Source: Self-asserted source
Estibaliz Capetillo-Zarate

Funding (4)

Neurogenomiks group

2018 to 2021 | Grant
Euskal Herriko Unibertsitatea (Leioa, ES)
GRANT_NUMBER:

GUI17/034
Source: Self-asserted source
Estibaliz Capetillo-Zarate

Modulación glía-sinapsis como diana terapéutica en la enfermedad de Alzheimer

2017 to 2019 | Grant
Basque Government (Vitoria-Gasteiz, ES)
GRANT_NUMBER:

PI-2016-1-009-0016
Source: Self-asserted source
Estibaliz Capetillo-Zarate

Evaluación del efecto neuroprotector de extractos polifenólicos procedentes de la uva y el vino

2017 to 2018 | Grant
Basque Government (Vitoria-Gasteiz, ES)
GRANT_NUMBER:

2016-00033
Source: Self-asserted source
Estibaliz Capetillo-Zarate

Role of microglia in Alzheimer disease

2014-11 to 2019-10 | Grant
Ikerbasque, Basque Foundation for Science (Bilbao, ES)
Source: Self-asserted source
Estibaliz Capetillo-Zarate

Works (32)

Whole Blood Expression Pattern of Inflammation and Redox Genes in Mild Alzheimer’s Disease

Journal of Inflammation Research
2021-11 | Journal article
DOI: 10.2147/jir.s334337
Part of ISSN: 1178-7031
Source: Self-asserted source
Estibaliz Capetillo-Zarate

Microglial phagocytosis dysfunction during stroke is prevented by rapamycin

2021-11-13 | Other
DOI: 10.1101/2021.11.12.468358
Contributors: S Beccari; V Sierra-Torre; J Valero; M García-Zaballa; A Carretero-Guillen; E Capetillo-Zarate; M Domercq; PR Huguet; D Ramonet; A Osman et al.
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Longitudinal evaluation of a novel BChE PET tracer as an early <i>in vivo</i> biomarker in the brain of a mouse model for Alzheimer disease.

Theranostics
2021-04-26 | Journal article
DOI: 10.7150/thno.54589
PMID: 33995675
PMC: PMC8120209
Source: Self-asserted source
Estibaliz Capetillo-Zarate

Effects of Platelet-Rich Plasma on Cellular Populations of the Central Nervous System: The Influence of Donor Age.

International journal of molecular sciences
2021-02-09 | Journal article
DOI: 10.3390/ijms22041725
PMID: 33572157
PMC: PMC7915891
Source: Self-asserted source
Estibaliz Capetillo-Zarate

APP depletion alters selective pre- and post-synaptic proteins

Molecular and Cellular Neuroscience
2019 | Journal article
DOI: 10.1016/j.mcn.2019.02.003
EID:

2-s2.0-85061606518
Contributors: Martinsson, I.; Capetillo-Zarate, E.; Faideau, M.; Willén, K.; Esteras, N.; Frykman, S.; Tjernberg, L.O.; Gouras, G.K.
Source: Self-asserted source
Estibaliz Capetillo-Zarate via Scopus - Elsevier

P2X4 receptor controls microglia activation and favors remyelination in autoimmune encephalitis

EMBO Molecular Medicine
2018 | Journal article
DOI: 10.15252/emmm.201708743
EID:

2-s2.0-85050460754
Contributors: Zabala, A.; Vazquez-Villoldo, N.; Rissiek, B.; Gejo, J.; Martin, A.; Palomino, A.; Perez-Samartín, A.; Pulagam, K.R.; Lukowiak, M.; Capetillo-Zarate, E. et al.
Source: Self-asserted source
Estibaliz Capetillo-Zarate via Scopus - Elsevier

Contribution of Neurons and Glial Cells to Complement-Mediated Synapse Removal during Development, Aging and in Alzheimer’s Disease

Mediators of Inflammation
2018-11-11 | Journal article
DOI: 10.1155/2018/2530414
Contributors: Celia Luchena; Jone Zuazo-Ibarra; Elena Alberdi; Carlos Matute; Estibaliz Capetillo-Zarate
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Mangiferin and Morin Attenuate Oxidative Stress, Mitochondrial Dysfunction, and Neurocytotoxicity, Induced by Amyloid Beta Oligomers

Oxidative Medicine and Cellular Longevity
2018-06 | Journal article
DOI: 10.1155/2018/2856063
Part of ISSN: 1942-0900
Contributors: Elena Alberdi; María Victoria Sánchez-Gómez; Asier Ruiz; Fabio Cavaliere; Carolina Ortiz-Sanz; Tania Quintela-López; Estibaliz Capetillo-Zarate; Santiago Solé-Domènech; Carlos Matute
Source: Self-asserted source
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Targeting Beta-Amyloid at the CSF: A New Therapeutic Strategy in Alzheimer’s Disease

Frontiers in Aging Neuroscience
2018-04 | Journal article
DOI: 10.3389/fnagi.2018.00100
Part of ISSN: 1663-4365
Contributors: Manuel Menendez-Gonzalez; Huber S. Padilla-Zambrano; Gabriel Alvarez; Estibaliz Capetillo-Zarate; Cristina Tomas-Zapico; Agustin Costa
Source: Self-asserted source
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Synaptic activity protects against AD and FTD-like pathology via autophagic-lysosomal degradation

Molecular Psychiatry
2017-07-11 | Journal article
DOI: 10.1038/mp.2017.142
Part of ISSN: 1359-4184
Contributors: Y Akwa; E Gondard; A Mann; E Capetillo-Zarate; E Alberdi; C Matute; S Marty; T Vaccari; A M Lozano; E E Baulieu et al.
Source: Self-asserted source
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The endocytic pathway in microglia during health, aging and Alzheimer’s disease

Ageing Research Reviews
2016 | Journal article
DOI: 10.1016/j.arr.2016.07.002
Part of ISSN: 1568-1637
Contributors: Santiago Solé-Domènech; Dana L. Cruz; Estibaliz Capetillo-Zarate; Frederick R. Maxfield
Source: Self-asserted source
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Monocyte-Derived Dendritic Cells Upregulate Extracellular Catabolism of Aggregated Low-Density Lipoprotein on Maturation, Leading to Foam Cell FormationSignificance

Arteriosclerosis, Thrombosis, and Vascular Biology
2015-08 | Journal article
DOI: 10.1161/atvbaha.115.305843
Part of ISSN: 1079-5642
Contributors: Abigail S. Haka; Rajesh K. Singh; Inna Grosheva; Haley Hoffner; Estibaliz Capetillo-Zarate; Harvey F. Chin; Niroshana Anandasabapathy; Frederick R. Maxfield
Source: Self-asserted source
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Accumulation of Intraneuronal β-Amyloid 42 Peptides Is Associated with Early Changes in Microtubule-Associated Protein 2 in Neurites and Synapses

PLoS ONE
2013-01 | Journal article
DOI: 10.1371/journal.pone.0051965
Part of ISSN: 1932-6203
Contributors: Reisuke H. Takahashi; Estibaliz Capetillo-Zarate; Michael T. Lin; Teresa A. Milner; Gunnar K. Gouras; Koichi M. Iijima
Source: Self-asserted source
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Intraneuronal Aß Accumulation, Amyloid Plaques, and Synapse Pathology in Alzheimer’s Disease

Neurodegenerative Diseases
2012 | Journal article
DOI: 10.1159/000334762
Part of ISSN: 1660-2862
Contributors: Estibaliz Capetillo-Zarate; Luis Gracia; Davide Tampellini; Gunnar K. Gouras
Source: Self-asserted source
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Transgenic expression of intraneuronal Aβ42 but not Aβ40 leads to cellular Aβ lesions, degeneration, and functional impairment without typical Alzheimer's disease pathology

Journal of Neuroscience
2012 | Journal article
DOI: 10.1523/JNEUROSCI.4586-11.2012
EID:

2-s2.0-84856296092
Contributors: Abramowski, D.; Rabe, S.; Upadhaya, A.R.; Reichwald, J.; Danner, S.; Staab, D.; Capetillo-Zarate, E.; Yamaguchi, H.; Saido, T.C.; Wiederhold, K.-H. et al.
Source: Self-asserted source
Estibaliz Capetillo-Zarate via Scopus - Elsevier

Dispersible amyloid β-protein oligomers, protofibrils, and fibrils represent diffusible but not soluble aggregates: their role in neurodegeneration in amyloid precursor protein (APP) transgenic mice

Neurobiology of Aging
2012-11 | Journal article
DOI: 10.1016/j.neurobiolaging.2011.12.032
Part of ISSN: 0197-4580
Contributors: Ajeet Rijal Upadhaya; Estibaliz Capetillo-Zarate; Irina Kosterin; Dorothee Abramowski; Sathish Kumar; Haruyasu Yamaguchi; Jochen Walter; Marcus Fändrich; Matthias Staufenbiel; Dietmar Rudolf Thal
Source: Self-asserted source
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High-Resolution 3D Reconstruction Reveals Intra-Synaptic Amyloid Fibrils

The American Journal of Pathology
2011-11 | Journal article
DOI: 10.1016/j.ajpath.2011.07.045
Part of ISSN: 0002-9440
Contributors: Estibaliz Capetillo-Zarate; Luis Gracia; Fangmin Yu; Jason R. Banfelder; Michael T. Lin; Davide Tampellini; Gunnar K. Gouras
Source: Self-asserted source
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Impaired  -Amyloid Secretion in Alzheimer's Disease Pathogenesis

Journal of Neuroscience
2011-10 | Journal article
DOI: 10.1523/jneurosci.2986-11.2011
Part of ISSN: 0270-6474
Contributors: D. Tampellini; N. Rahman; M. T. Lin; E. Capetillo-Zarate; G. K. Gouras
Source: Self-asserted source
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Degradation of Alzheimer's amyloid fibrils by microglia requires delivery of ClC-7 to lysosomes

Molecular Biology of the Cell
2011-05 | Journal article
DOI: 10.1091/mbc.e10-09-0745
Part of ISSN: 1059-1524
Contributors: Amitabha Majumdar; Estibaliz Capetillo-Zarate; Dana Cruz; Gunnar K. Gouras; Frederick R. Maxfield; Keith E. Mostov
Source: Self-asserted source
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Effects of synaptic modulation on β-amyloid, synaptophysin, and memory performance in Alzheimer's disease transgenic mice

Journal of Neuroscience
2010 | Journal article
DOI: 10.1523/JNEUROSCI.3383-10.2010
EID:

2-s2.0-78049349176
Contributors: Tampellini, D.; Capetillo-Zarate, E.; Dumont, M.; Huang, Z.; Yu, F.; Lin, M.T.; Gouras, G.K.
Source: Self-asserted source
Estibaliz Capetillo-Zarate via Scopus - Elsevier

Dysregulation of the mTOR Pathway Mediates Impairment of Synaptic Plasticity in a Mouse Model of Alzheimer's Disease

PLoS ONE
2010-09 | Journal article
DOI: 10.1371/journal.pone.0012845
Part of ISSN: 1932-6203
Contributors: Tao Ma; Charles A. Hoeffer; Estibaliz Capetillo-Zarate; Fangmin Yu; Helen Wong; Michael T. Lin; Davide Tampellini; Eric Klann; Robert D. Blitzer; Gunnar K. Gouras et al.
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Co-occurrence of Alzheimer's disease β-amyloid and tau pathologies at synapses

Neurobiology of Aging
2010-07 | Journal article
DOI: 10.1016/j.neurobiolaging.2008.07.021
Part of ISSN: 0197-4580
Contributors: Reisuke H. Takahashi; Estibaliz Capetillo-Zarate; Michael T. Lin; Teresa A. Milner; Gunnar K. Gouras
Source: Self-asserted source
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Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease

Acta Neuropathologica
2010-03 | Journal article
DOI: 10.1007/s00401-010-0679-9
Part of ISSN: 0001-6322
Contributors: Gunnar K. Gouras; Davide Tampellini; Reisuke H. Takahashi; Estibaliz Capetillo-Zarate
Source: Self-asserted source
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Capillary cerebral amyloid angiopathy is associated with vessel occlusion and cerebral blood flow disturbances

Neurobiology of Aging
2009 | Journal article
DOI: 10.1016/j.neurobiolaging.2008.01.017
Part of ISSN: 0197-4580
Contributors: Dietmar Rudolf Thal; Estibaliz Capetillo-Zarate; Sergey Larionov; Matthias Staufenbiel; Stefan Zurbruegg; Nicolau Beckmann
Source: Self-asserted source
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Synaptic Activity Reduces Intraneuronal A , Promotes APP Transport to Synapses, and Protects against A -Related Synaptic Alterations

Journal of Neuroscience
2009-08-05 | Journal article
DOI: 10.1523/jneurosci.2292-09.2009
Part of ISSN: 0270-6474
Contributors: D. Tampellini; N. Rahman; E. F. Gallo; Z. Huang; M. Dumont; E. Capetillo-Zarate; T. Ma; R. Zheng; B. Lu; D. M. Nanus et al.
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Inter-laboratory comparison of neuropathological assessments of β-amyloid protein: a study of the BrainNet Europe consortium

Acta Neuropathologica
2008-03 | Journal article
DOI: 10.1007/s00401-008-0358-2
Part of ISSN: 0001-6322
Contributors: Irina Alafuzoff; Maria Pikkarainen; Thomas Arzberger; Dietmar R. Thal; Safa Al-Sarraj; Jeanne Bell; Istvan Bodi; Herbert Budka; Estibaliz Capetillo-Zarate; Isidro Ferrer et al.
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Tracing of temporo-entorhinal connections in the human brain: cognitively impaired argyrophilic grain disease cases show dendritic alterations but no axonal disconnection of temporo-entorhinal association neurons

Acta Neuropathologica
2007 | Journal article
DOI: 10.1007/s00401-007-0330-6
Part of ISSN: 0001-6322
Contributors: Dietmar Rudolf Thal; Estibaliz Capetillo-Zarate; Ralf A. Galuske
Source: Self-asserted source
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Occurrence and co-localization of amyloid β-protein and apolipoprotein E in perivascular drainage channels of wild-type and APP-transgenic mice

Neurobiology of Aging
2007-08 | Journal article
DOI: 10.1016/j.neurobiolaging.2006.05.029
Part of ISSN: 0197-4580
Contributors: Dietmar Rudolf Thal; Sergey Larionov; Dorothee Abramowski; Karl-Heinz Wiederhold; Tom Van Dooren; Haruyasu Yamaguchi; Christian Haass; Fred Van Leuven; Matthias Staufenbiel; Estibaliz Capetillo-Zarate
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Vesicular glutamate release from axons in white matter

Nature Neuroscience
2007-02-11 | Journal article
DOI: 10.1038/nn1850
Part of ISSN: 1097-6256
Contributors: Maria Kukley; Estibaliz Capetillo-Zarate; Dirk Dietrich
Source: Self-asserted source
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The development of amyloid beta protein deposits in the aged brain.

Science of aging knowledge environment : SAGE KE
2006 | Journal article
DOI: 10.1126/sageke.2006.6.re1
EID:

2-s2.0-33645226129
Contributors: Thal, D.R.; Capetillo-Zarate, E.; Del Tredici, K.; Braak, H.
Source: Self-asserted source
Estibaliz Capetillo-Zarate via Scopus - Elsevier

Selective vulnerability of different types of commissural neurons for amyloid  -protein-induced neurodegeneration in APP23 mice correlates with dendritic tree morphology

Brain
2006-09 | Journal article
DOI: 10.1093/brain/awl176
Part of ISSN: 0006-8950
Contributors: E. Capetillo-Zarate; M. Staufenbiel; D. Abramowski; C. Haass; A. Escher; C. Stadelmann; H. Yamaguchi; O. D. Wiestler; D. R. Thal
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Apolipoprotein E co-localizes with newly formed amyloid β-protein (Aβ) deposits lacking immunoreactivity against N-terminal epitopes of Aβ in a genotype-dependent manner

Acta Neuropathologica
2005-09 | Journal article
DOI: 10.1007/s00401-005-1053-1
Part of ISSN: 0001-6322
Contributors: Dietmar Rudolf Thal; Estibaliz Capetillo-Zarate; Christian Schultz; Udo Rüb; Takaomi C. Saido; Haruyasu Yamaguchi; Christian Haass; W. Sue T. Griffin; Kelly Del Tredici; Heiko Braak et al.
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