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Employment (4)

The University of Arizona College of Medicine Phoenix: Phoenix, AZ, US

2019-04-01 to present | Research Assistant Professor (Neurosurgery)
Employment
Source: Self-asserted source
Artak Tovmasyan

Barrow Neurological Institute: Phoenix, AZ, US

2019-01-09 to present | Associate Professor (Neurobiology)
Employment
Source: Self-asserted source
Artak Tovmasyan

Duke University School of Medicine: Durham, NC, US

2009 to 2018-12-31 | Research Associate (Radiation Oncology)
Employment
Source: Self-asserted source
Artak Tovmasyan

Yerevan State Medical University Named after Mkhitar Heratsi: Yerevan, AM

2008 to 2009 | Assistant Professor (Organic Chemistry)
Employment
Source: Self-asserted source
Artak Tovmasyan

Education and qualifications (4)

Yerevan State Medical University Named after Mkhitar Heratsi: Yerevan, AM

2005 to 2008 | PhD (Pharmaceutical Chemistry)
Education
Source: Self-asserted source
Artak Tovmasyan

Yerevan State Medical University Named after Mkhitar Heratsi: Yerevan, AM

2004 to 2005 | Residency (Pharmaceutical Chemistry)
Education
Source: Self-asserted source
Artak Tovmasyan

Yerevan State Medical University Named after Mkhitar Heratsi: Yerevan, AM

2003 to 2004 | Internship (Pharmaceutical Chemistry)
Education
Source: Self-asserted source
Artak Tovmasyan

Yerevan State Medical University Named after Mkhitar Heratsi: Yerevan, AM

1998-09-01 to 2003-06 | MS (School of Pharmacy)
Education
Source: Self-asserted source
Artak Tovmasyan

Works (44)

Minibeam Spatially-Fractionated Radiation Therapy Is Superior to Uniform Dose Radiation Therapy for Abscopal Effect When Combined with PD-L1 Checkpoint Inhibitor Immunotherapy in a Dual Tumor Murine Mammary Carcinoma Model

Radiation
2025-01-02 | Journal article
Contributors: Judith N. Rivera; Keith Laemont; Artak Tovmasyan; Stefan Stryker; Kenneth Young; Theresa Charity; Gregory M. Palmer; Sha Chang
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Mechanistic Modeling of Spatial Heterogeneity of Drug Penetration and Exposure in the Human Central Nervous System and Brain Tumors

Clinical Pharmacology & Therapeutics
2024-11-22 | Journal article
Contributors: Jing Li; Charuka Wickramasinghe; Jun Jiang; Andrew Wu; Yuanyuan Jiang; Artak Tovmasyan; Seongho Kim; Nader Sanai
Source: check_circle
Crossref

Folic Acid Improves Parkin-Null Drosophila Phenotypes and Transiently Reduces Vulnerable Dopaminergic Neuron Mitochondrial Hydrogen Peroxide Levels and Glutathione Redox Equilibrium

Antioxidants
2022-10-20 | Journal article
Contributors: Katherine L. Houlihan; Petros P. Keoseyan; Amber N. Juba; Tigran Margaryan; Max E. Voss; Alexander M. Babaoghli; Justin M. Norris; Greg J. Adrian; Artak Tovmasyan; Lori M. Buhlman
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Crossref
grade
Preferred source (of 2)‎

Simultaneous determination of LY3214996, abemaciclib, and M2 and M20 metabolites in human plasma, cerebrospinal fluid, and brain tumor by LC-MS/MS

Journal of Pharmaceutical Analysis
2022-08 | Journal article
Contributors: Tigran Margaryan; Mackenna Elliott; Nader Sanai; Artak Tovmasyan
Source: check_circle
Crossref

A Redox-active Mn Porphyrin, MnTnBuOE-2-PyP5+, Synergizes with Carboplatin in Treatment of Chemoresistant Ovarian Cell Line

Oxidative Medicine and Cellular Longevity
2022-05-09 | Journal article
Contributors: Luksana Chaiswing; Chontida Yarana; William St. Clair; Artak Tovmasyan; Ines Batinic-Haberle; Ivan Spasojevic; Daret St. Clair; Dilipkumar Pal
Source: check_circle
Crossref

H2O2‐Driven Anticancer Activity of Mn Porphyrins and the Underlying Molecular Pathways

Oxidative Medicine and Cellular Longevity
2021-01 | Journal article
Contributors: Ines Batinic-Haberle; Artak Tovmasyan; Zhiqing Huang; Weina Duan; Li Du; Sharareh Siamakpour-Reihani; Zhipeng Cao; Huaxin Sheng; Ivan Spasojevic; Angeles Alvarez Secord et al.
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Crossref

Antibacterial Activity of Synthetic Cationic Iron Porphyrins

Antioxidants
2020-10 | Journal article | Author
Contributors: Artak Tovmasyan; Ines Batinic-Haberle; Ludmil Benov
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Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Manganese porphyrin redox state in endothelial cells: Resonance Raman studies and implications for antioxidant protection towards peroxynitrite

Free Radical Biology and Medicine
2018-10 | Journal article
Contributors: Sebastián Carballal; Valeria Valez; Damián Alvarez-Paggi; Artak Tovmasyan; Ines Batinic-Haberle; Gerardo Ferrer-Sueta; Daniel H. Murgida; Rafael Radi
Source: check_circle
Crossref

Robust rat pulmonary radioprotection by a lipophilic Mn N-alkylpyridylporphyrin, MnTnHex-2-PyP5+

2014 | Journal article
DOI:

10.1016/j.redox.2013.12.017

Part of ISSN:

2213-2317

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search

Comprehensive pharmacokinetic studies and oral bioavailability of two Mn porphyrin-based SOD mimics, MnTE-2-PyP5+ and MnTnHex-2-PyP 5+

Free Radical Biology and Medicine
2013 | Journal article
DOI:

10.1016/j.freeradbiomed.2013.01.006

Contributors: Weitner, T.; Kos, I.; Sheng, H.; Tovmasyan, A.; Reboucas, J.S.; Fan, P.; Warner, D.S.; Vujaskovic, Z.; Batinic-Haberle, I.; Spasojevic, I.
Source: Self-asserted source
Artak Tovmasyan via Scopus - Elsevier

Design, mechanism of action, bioavailability and therapeutic effects of Mn porphyrin-based redox modulators

Medical Principles and Practice
2013 | Journal article
DOI:

10.1159/000341715

Contributors: Tovmasyan, A.; Sheng, H.; Weitner, T.; Arulpragasam, A.; Lu, M.; Warner, D.S.; Vujaskovic, Z.; Spasojevic, I.; Batinic-Haberle, I.
Source: Self-asserted source
Artak Tovmasyan via Scopus - Elsevier

Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology

Inorganic Chemistry
2013 | Journal article
DOI:

10.1021/ic3012519

Contributors: Tovmasyan, A.; Weitner, T.; Sheng, H.; Lu, M.; Rajic, Z.; Warner, D.S.; Spasojevic, I.; Reboucas, J.S.; Benov, L.; Batinic-Haberle, I.
Source: Self-asserted source
Artak Tovmasyan via Scopus - Elsevier

Effect of molecular characteristics on cellular uptake, subcellular localization, and phototoxicity of Zn(2) N-Alkylpyridylporphyrins

Journal of Biological Chemistry
2013 | Journal article
DOI:

10.1074/jbc.M113.511642

Contributors: Ezzeddine, R.; Al-Banaw, A.; Tovmasyan, A.; Craik, J.D.; Batinic-Haberle, I.; Benov, L.T.
Source: Self-asserted source
Artak Tovmasyan via Scopus - Elsevier

Late administration of Mn porphyrin-based SOD mimic enhances diabetic complications

Redox Biology
2013 | Journal article
DOI:

10.1016/j.redox.2013.09.005

Contributors: Ali, D.K.; Oriowo, M.; Tovmasyan, A.; Batinic-Haberle, I.; Benov, L.
Source: Self-asserted source
Artak Tovmasyan via Scopus - Elsevier

Manganese-Based Superoxide Dismutase Mimics Modify Both Acute and Long-Term Outcome Severity in a Drosophila melanogaster Model of Classic Galactosemia

2013 | Journal article
DOI:

10.1089/ars.2012.5122

Part of ISSN:

1523-0864

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search

Metalloporphyrins as Therapeutic Catalytic Oxidoreductants in Central Nervous System Disorders

2013 | Journal article
DOI:

10.1089/ars.2013.5413

Part of ISSN:

1523-0864

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search

Mn porphyrin in combination with ascorbate acts as a pro-oxidant and mediates caspase-independent cancer cell death

2013 | Journal article
DOI:

10.1016/j.freeradbiomed.2013.11.031

Part of ISSN:

0891-5849

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search
grade
Preferred source (of 2)‎

Mn porphyrin regulation of aerobic glycolysis: Implications on the activation of diabetogenic immune cells

Antioxidants and Redox Signaling
2013 | Journal article
DOI:

10.1089/ars.2012.5167

Contributors: Delmastro-Greenwood, M.M.; Votyakova, T.; Goetzman, E.; Marre, M.L.; Previte, D.M.; Tovmasyan, A.; Batinic-Haberle, I.; Trucco, M.M.; Piganelli, J.D.
Source: Self-asserted source
Artak Tovmasyan via Scopus - Elsevier

Simple Biological Systems for Assessing the Activity of Superoxide Dismutase Mimics

2013 | Journal article
DOI:

10.1089/ars.2013.5576

Part of ISSN:

1523-0864

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search

SOD Therapeutics: Latest Insights into Their Structure-Activity Relationships and Impact on the Cellular Redox-Based Signaling Pathways

2013 | Journal article
DOI:

10.1089/ars.2012.5147

Part of ISSN:

1523-0864

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search

Superoxide dismutase mimic, MnTE-2-PyP5+ ameliorates acute and chronic proctitis following focal proton irradiation of the rat rectum

2013 | Journal article
DOI:

10.1016/j.redox.2013.10.002

Part of ISSN:

2213-2317

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search

A new SOD mimic, Mn(III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity

Free Radical Biology and Medicine
2012 | Journal article
DOI:

10.1016/j.freeradbiomed.2012.02.006

Contributors: Rajic, Z.; Tovmasyan, A.; Spasojevic, I.; Sheng, H.; Lu, M.; Li, A.M.; Gralla, E.B.; Warner, D.S.; Benov, L.; Batinic-Haberle, I.
Source: Self-asserted source
Artak Tovmasyan via Scopus - Elsevier

Comprehensive Pharmacokinetic Studies and Biodistribution of Two Cationic Mn Porphyrin-Based Catalysts, MnTE-2-PyP5+ and MnTnHex-2-PyP5+: Plasma and Organ Oral Availability, Mitochondrial, Cytosolic, Whole Brain, Hippocampus and Cortex Distribution

2012 | Journal article
DOI:

10.1016/j.freeradbiomed.2012.10.291

Part of ISSN:

0891-5849

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search

Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities

Amino Acids
2012 | Journal article
DOI:

10.1007/s00726-010-0603-6

Contributors: Batinic-Haberle, I.; Spasojevic, I.; Tse, H.M.; Tovmasyan, A.; Rajic, Z.; Clair, D.K.St.; Vujaskovic, Z.; Dewhirst, M.W.; Piganelli, J.D.
Source: Self-asserted source
Artak Tovmasyan via Scopus - Elsevier

Erratum to: Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities

2012 | Journal article
DOI:

10.1007/s00726-010-0821-y

Part of ISSN:

0939-4451

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search

Manganese superoxide dismutase, MnSOD and its mimics

2012 | Journal article
DOI:

10.1016/j.bbadis.2011.12.002

Part of ISSN:

0925-4439

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search

Mn porphyrins as novel molecular magnetic resonance imaging contrast agents

Journal of Endourology
2012 | Journal article
DOI:

10.1089/end.2012.0171

Contributors: Mouraviev, V.; Venkatraman, T.N.; Tovmasyan, A.; Kimura, M.; Tsivian, M.; Mouravieva, V.; Polascik, T.J.; Wang, H.; Amrhein, T.J.; Batinic-Haberle, I. et al.
Source: Self-asserted source
Artak Tovmasyan via Scopus - Elsevier

Understanding Differences in Mechanisms of Action of Fe vs Mn Porphyrins: Comparison of Their Reactivities Towards Cellular Reductants and Reactive Species

2012 | Journal article
DOI:

10.1016/j.freeradbiomed.2012.10.297

Part of ISSN:

0891-5849

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search

A Breakthrough in the Development of SOD Mimics/Cellular Redox Modulators: a Superior Mn porphyrin, MnTnBuOE-2-PyP5+ With Finely Tuned Properties

2011 | Journal article
DOI:

10.1016/j.freeradbiomed.2011.10.462

Part of ISSN:

0891-5849

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search

Cytotoxic effects of Mn(III) N -alkylpyridylporphyrins in the presence of cellular reductant, ascorbate

2011 | Journal article
DOI:

10.3109/10715762.2011.616199

Part of ISSN:

1071-5762

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search

Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics

Free Radical Biology and Medicine
2011 | Journal article
DOI:

10.1016/j.freeradbiomed.2011.04.046

Contributors: Batinic-Haberle, I.; Rajic, Z.; Tovmasyan, A.; Reboucas, J.S.; Ye, X.; Leong, K.W.; Dewhirst, M.W.; Vujaskovic, Z.; Benov, L.; Spasojevic, I.
Source: Self-asserted source
Artak Tovmasyan via Scopus - Elsevier

Experimental and Computational Studies on Mn Porphyrin-Based Therapeutics: Unforeseen Intramolecular Rearrangements on Methoxyalkyl Analogues of MnTE-2-PyP5+ and MnTnHex-2-PyP5+

2011 | Journal article
DOI:

10.1016/j.freeradbiomed.2011.10.256

Part of ISSN:

0891-5849

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search

Fe porphyrins Revisited: Synthesis, Characterization and the Effects of Ortho and Meta Fe(III) N-Alkylpyridylporphyrins Upon the Growth of E. Coli in the Presence and Absence of Ascorbate

2011 | Journal article
DOI:

10.1016/j.freeradbiomed.2011.10.475

Part of ISSN:

0891-5849

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search

Lipophilic Mn Porphyrins in the Treatment of Brain Tumors

2011 | Journal article
DOI:

10.1016/j.freeradbiomed.2011.10.309

Part of ISSN:

0891-5849

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search

Lipophilicity of Mn(III) N-Alkylpyridylporphyrins Dominates Their Accumulation Within Mitochondria and Therefore in Vivo Efficacy: a Mouse Study

2011 | Journal article
DOI:

10.1016/j.freeradbiomed.2011.10.473

Part of ISSN:

0891-5849

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search

Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(iii) N-methoxyalkylpyridylporphyrins

Dalton Transactions
2011 | Journal article
DOI:

10.1039/c0dt01321h

Contributors: Tovmasyan, A.G.; Rajic, Z.; Spasojevic, I.; Reboucas, J.S.; Chen, X.; Salvemini, D.; Sheng, H.; Warner, D.S.; Benov, L.; Batinic-Haberle, I.
Source: Self-asserted source
Artak Tovmasyan via Scopus - Elsevier

Mn-porphyrins as novel molecular magnetic resonance imaging contrast agents.

Journal of endourology / Endourological Society
2011 | Journal article
Contributors: Mouraviev, V.; Venkatraman, T.N.; Tovmasyan, A.; Kimura, M.; Tsivian, M.; Mouravieva, V.; Polascik, T.J.; Wang, H.; Amrhein, T.J.; Batinic-Haberle, I. et al.
Source: Self-asserted source
Artak Tovmasyan via Scopus - Elsevier

Accumulation of Porphyrin-based SOD Mimics in Mitochondria is Proportional to Their Lipophilicity: S. cerevisiae Study of ortho Mn(III) N-alkylpyridylporphyrins

2010 | Journal article
DOI:

10.1016/j.freeradbiomed.2010.10.576

Part of ISSN:

0891-5849

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search

Cationic Mn Porphyrins Change Their Action from anti- to pro-oxidative in the Presence of Cellular Reductants: Relevance to understanding the beneficial therapeutic effects of SOD mimics in vivo

2010 | Journal article
DOI:

10.1016/j.freeradbiomed.2010.10.560

Part of ISSN:

0891-5849

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search

Structural Modification Diminishes Toxicity of Lipophilic Longer Mn(III) N-alkylpyridyl porphyrin-based Powerful SOD Mimics: Synthesis, Characterization and SOD-deficient E. coli and S. cerevisiae studies

2010 | Journal article
DOI:

10.1016/j.freeradbiomed.2010.10.583

Part of ISSN:

0891-5849

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search

<title>Photodynamic inactivation of Gram (-) and Gram (+) microorganisms by cationic porphyrins and metalloporphyrins</title>

2009 | Conference paper
DOI:

10.1117/12.823002

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search

Synthesis and in vitro anticancer activity of water-soluble cationic pyridylporphyrins and their metallocomplexes

2008 | Journal article
DOI:

10.1142/s1088424608000467

Part of ISSN:

1088-4246

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search
grade
Preferred source (of 2)‎

In vitro testing of cyto- and genotoxicity of new porphyrin water-soluble metal derivatives

International Journal of Toxicology
2007 | Journal article
DOI:

10.1080/10915810701707056

Contributors: Gasparyan, G.; Hovhannisyan, G.; Ghazaryan, R.; Sahakyan, L.; Tovmasyan, A.; Grigoryan, R.; Sarkissyan, N.; Haroutiunian, S.; Aroutiounian, R.
Source: Self-asserted source
Artak Tovmasyan via Scopus - Elsevier

The complex mechanistic aspects of redox-active compounds, commonly regarded as SOD mimics

Journal article
DOI:

10.1515/irm-2013-0004

Part of ISSN:

2191-2491

Source: Self-asserted source
Artak Tovmasyan via Crossref Metadata Search