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Employment (4)

Genentech Inc: South San Francisco, CA, US

2008 to 2019 | Vice President, Neuroscience (Research and Early Development)
Employment
Source: Self-asserted source
Morgan Sheng

Massachusetts Institute of Technology: Cambridge, MA, US

2001 to 2008 | Professor of Neuroscience (Brain and Cognitive Sciences; and Biology)
Employment
Source: Self-asserted source
Morgan Sheng

Howard Hughes Medical Institute: Chevy Chase, MD, US

1994 to 2008 | Investigator
Employment
Source: Self-asserted source
Morgan Sheng

Massachusetts General Hospital and Harvard Medical School, Boston MA US: Boston, MA, US

1994 to 2001 | Assistant Professor/Associate Professor (Neurobiology)
Employment
Source: Self-asserted source
Morgan Sheng

Professional activities (7)

Society for Neuroscience: Washington, DC, US

1995 to present | Regular
Membership
Source: Self-asserted source
Morgan Sheng

University of Oxford Corpus Christi College: Oxford, Oxfordshire, GB

2010 | Honorary Fellow
Distinction
Source: Self-asserted source
Morgan Sheng

Academy of Medical Sciences: London, London, GB

2009 | Fellow
Distinction
Source: Self-asserted source
Morgan Sheng

Royal Society: London, GB

2007 | Fellow
Distinction
Source: Self-asserted source
Morgan Sheng

Fondation IPSEN: Boulogne-Billancourt, FR

2006 | Neuronal Plasticity Prize
Distinction
Source: Self-asserted source
Morgan Sheng

American Association For The Advancement of Science: Washington D.C., District of Columbia, US

2004 | Fellow
Distinction
Source: Self-asserted source
Morgan Sheng

Society for Neuroscience: Washington, DC, US

1999 | Young Investigator Award
Distinction
Source: Self-asserted source
Morgan Sheng

Works (50 of 198)

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Page 1 of 4

Grin2aHypofunction Disrupts Hippocampal Network Oscillations and E/I Balance Contributing to Cognitive Deficits

2024-11-10 | Preprint
Contributors: Hassan Hosseini; Jean C. Rodríguez Díaz; Dominique L. Pritchett; Morgan Sheng; Kevin S. Jones
Source: check_circle
Crossref

Synaptic composition, activity, mRNA translation and dynamics in combined single-synapse profiling using multimodal imaging

2024-10-28 | Preprint
Contributors: Reuven Falkovich; Sameer Aryal; Jasmine Wang; Morgan Sheng; Mark Bathe
Source: check_circle
Crossref

Targeting synapse function and loss for treatment of neurodegenerative diseases

Nature Reviews Drug Discovery
2024-01 | Journal article
Contributors: Borislav Dejanovic; Morgan Sheng; Jesse E. Hanson
Source: check_circle
Crossref

Differential Functional Consequences ofGRIN2AMutations Associated with Schizophrenia and Neurodevelopmental Disorders

2023-08-03 | Preprint
Contributors: Nate Shepard; David Baez-Nieto; Sumaiya Iqbal; Erkin Kurganov; Nikita Budnik; Arthur J. Campbell; Jen Q Pan; Morgan Sheng; Zohreh Farsi
Source: check_circle
Crossref

The neuronal pentraxin Nptx2 regulates complement activity and restrains microglia-mediated synapse loss in neurodegeneration

Science Translational Medicine
2023-03-29 | Journal article
Contributors: Jiechao Zhou; Sarah D. Wade; David Graykowski; Mei-Fang Xiao; Binhui Zhao; Lucia A. A. Giannini; Jesse E. Hanson; John C. van Swieten; Morgan Sheng; Paul F. Worley et al.
Source: check_circle
Crossref

Mouse mutants in schizophrenia risk genes GRIN2A and AKAP11 show EEG abnormalities in common with schizophrenia patients

Translational Psychiatry
2023-03-13 | Journal article
Contributors: Linnea E. Herzog; Lei Wang; Eunah Yu; Soonwook Choi; Zohreh Farsi; Bryan J. Song; Jen Q. Pan; Morgan Sheng
Source: check_circle
Crossref

Deep proteomics identifies shared molecular pathway alterations in synapses of schizophrenia and bipolar disorder patients and mouse model

2022-09-22 | Preprint
Contributors: Sameer Aryal; Kevin Bonanno; Bryan Song; D.R. Mani; Hasmik Keshishian; Steven A. Carr; Morgan Sheng; Borislav Dejanovic
Source: check_circle
Crossref

Perturbations of a causal synaptic molecular network in autism and schizophrenia revealed with multiplexed imaging

2022-07-11 | Preprint
Contributors: Reuven Falkovich; Eric W. Danielson; Karen Perez de-Arce; Eike C. Wamhoff; Jeffrey Cottrell; Morgan Sheng; Mark Bathe
Source: check_circle
Crossref

Mouse mutants in schizophrenia risk genes GRIN2A and AKAP11 show EEG abnormalities in common with schizophrenia patients

2022-04-07 | Preprint
Contributors: Linnea E. Herzog; Lei Wang; Eunah Yu; Soonwook Choi; Zohreh Farsi; Bryan Song; Jen Q. Pan; Morgan Sheng
Source: check_circle
Crossref

PCDH7 interacts with GluN1 and regulates dendritic spine morphology and synaptic function

Scientific Reports
2020-07-02 | Journal article
Contributors: Yuanyuan Wang; Meghan Kerrisk Campbell; Irene Tom; Oded Foreman; Jesse E. Hanson; Morgan Sheng
Source: check_circle
Crossref

Microglia in Brain Development, Homeostasis, and Neurodegeneration

Annual Review of Genetics
2019 | Journal article
Part of ISSN: 0066-4197
Contributors: Christopher J. Bohlen; Brad A. Friedman; Borislav Dejanovic; Morgan Sheng
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

PTCD1 Is Required for Mitochondrial Oxidative-Phosphorylation: Possible Genetic Association with Alzheimer's Disease

The Journal of Neuroscience
2019-04-04 | Journal article
Part of ISSN: 0270-6474
Contributors: Daniel Fleck; Lilian Phu; Erik Verschueren; Trent Hinkle; Mike Reichelt; Tushar Bhangale; Benjamin Haley; Yuanyuan Wang; Robert Graham; Donald S. Kirkpatrick et al.
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies

Neuron
2018 | Journal article
Part of ISSN: 0896-6273
Contributors: Borislav Dejanovic; Melanie A. Huntley; Ann De Mazière; William J. Meilandt; Tiffany Wu; Karpagam Srinivasan; Zhiyu Jiang; Vineela Gandham; Brad A. Friedman; Hai Ngu et al.
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Morgan Sheng

Neuron
2018-06 | Journal article
Part of ISSN: 0896-6273
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

USP8 Deubiquitinates SHANK3 to Control Synapse Density and SHANK3 Activity-Dependent Protein Levels

The Journal of Neuroscience
2018-06-06 | Journal article
Contributors: Meghan Kerrisk Campbell; Morgan Sheng
Source: check_circle
Crossref

Microglia in Alzheimer’s disease

Journal of Cell Biology
2018-02-05 | Journal article
Contributors: David V. Hansen; Jesse E. Hanson; Morgan Sheng
Source: check_circle
Crossref

Morgan Sheng

Nature Reviews Drug Discovery
2018-01 | Journal article
Part of ISSN: 1474-1776
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Progranulin deficiency causes impairment of autophagy and TDP-43 accumulation

Journal of Experimental Medicine
2017-09-04 | Journal article
Contributors: Michael C. Chang; Karpagam Srinivasan; Brad A. Friedman; Eric Suto; Zora Modrusan; Wyne P. Lee; Joshua S. Kaminker; David V. Hansen; Morgan Sheng
Source: check_circle
Crossref

TREM2, Microglia, and Neurodegenerative Diseases

Trends in Molecular Medicine
2017-06 | Journal article
Part of ISSN: 1471-4914
Contributors: Felix L. Yeh; David V. Hansen; Morgan Sheng
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Diverse modes of NMDA receptor positive allosteric modulation: Mechanisms and consequences

Neuropharmacology
2017-01 | Journal article
Part of ISSN: 0028-3908
Contributors: David H. Hackos; Jesse E. Hanson
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Mechanisms of mitophagy: PINK1, Parkin, USP30 and beyond

Free Radical Biology and Medicine
2016-11 | Journal article
Part of ISSN: 0891-5849
Contributors: Baris Bingol; Morgan Sheng
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Interfering with the Chronic Immune Response Rescues Chronic Degeneration After Traumatic Brain Injury

Journal of Neuroscience
2016-09 | Journal article
Part of ISSN: 0270-6474
Contributors: A. Erturk; S. Mentz; E. E. Stout; M. Hedehus; S. L. Dominguez; L. Neumaier; F. Krammer; G. Llovera; K. Srinivasan; D. V. Hansen et al.
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia

Neuron
2016-07 | Journal article
Part of ISSN: 0896-6273
Contributors: Felix L. Yeh; Yuanyuan Wang; Irene Tom; Lino C. Gonzalez; Morgan Sheng
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function

Neuron
2016-03 | Journal article
Part of ISSN: 0896-6273
Contributors: David H. Hackos; Patrick J. Lupardus; Teddy Grand; Yelin Chen; Tzu-Ming Wang; Paul Reynen; Amy Gustafson; Heidi J.A. Wallweber; Matthew Volgraf; Benjamin D. Sellers et al.
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Characterization of Social Behaviors in caspase-3 deficient mice

Scientific Reports
2016-01 | Journal article
Part of ISSN: 2045-2322
Contributors: Shih-Ching Lo; Kimberly Scearce-Levie; Morgan Sheng
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Caspase-3 Deficiency Results in Disrupted Synaptic Homeostasis and Impaired Attention Control

Journal of Neuroscience
2015-02-04 | Journal article
Part of ISSN: 0270-6474
Contributors: S.-C. Lo; Y. Wang; M. Weber; J. L. Larson; K. Scearce-Levie; M. Sheng
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

A Septin-Dependent Diffusion Barrier at Dendritic Spine Necks

PLoS ONE
2014 | Journal article
Part of ISSN: 1932-6203
Contributors: Helge Ewers; Tomoko Tada; Jennifer D. Petersen; Bence Racz; Morgan Sheng; Daniel Choquet; Lin Mei
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Regulation of Neuronal Gene Expression and Survival by Basal NMDA Receptor Activity: A Role for Histone Deacetylase 4

Journal of Neuroscience
2014-11 | Journal article
Part of ISSN: 0270-6474
Contributors: Y. Chen; Y. Wang; Z. Modrusan; M. Sheng; J. S. Kaminker
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Activity-Induced Nr4a1 Regulates Spine Density and Distribution Pattern of Excitatory Synapses in Pyramidal Neurons

Neuron
2014-07 | Journal article
Part of ISSN: 0896-6273
Contributors: Yelin Chen; Yuanyuan Wang; Ali Ertürk; Dara Kallop; Zhiyu Jiang; Robby M. Weimer; Joshua Kaminker; Morgan Sheng
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy

Nature
2014-06-04 | Journal article
Part of ISSN: 0028-0836
Contributors: Baris Bingol; Joy S. Tea; Lilian Phu; Mike Reichelt; Corey E. Bakalarski; Qinghua Song; Oded Foreman; Donald S. Kirkpatrick; Morgan Sheng
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Local Pruning of Dendrites and Spines by Caspase-3-Dependent and Proteasome-Limited Mechanisms

Journal of Neuroscience
2014-01 | Journal article
Part of ISSN: 0270-6474
Contributors: A. Erturk; Y. Wang; M. Sheng
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Long-term depression: a cell biological view

Philosophical Transactions of the Royal Society B: Biological Sciences
2014-01-05 | Journal article
Part of ISSN: 0962-8436
Contributors: Morgan Sheng; Ali Ertürk
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

NMDA receptors in nervous system diseases

Neuropharmacology
2013-11 | Journal article
Part of ISSN: 0028-3908
Contributors: Qiang Zhou; Morgan Sheng
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

GPR3 Stimulates Aβ Production via Interactions with APP and β-Arrestin2

PLoS ONE
2013-09 | Journal article
Part of ISSN: 1932-6203
Contributors: Christopher D. Nelson; Morgan Sheng; Zhongcong Xie
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Phosphorylation of Threonine-19 of PSD-95 by GSK-3  is Required for PSD-95 Mobilization and Long-Term Depression

Journal of Neuroscience
2013-07 | Journal article
Part of ISSN: 0270-6474
Contributors: C. D. Nelson; M. J. Kim; H. Hsin; Y. Chen; M. Sheng
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

GluN2B Antagonism Affects Interneurons and Leads to Immediate and Persistent Changes in Synaptic Plasticity, Oscillations, and Behavior

Neuropsychopharmacology
2013-01 | Journal article
Part of ISSN: 0893-133X
Contributors: Jesse E Hanson; Martin Weber; William J Meilandt; Tiffany Wu; Tom Luu; Lunbin Deng; Mehrdad Shamloo; Morgan Sheng; Kimberly Scearce-Levie; Qiang Zhou
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Strength in numbers

Nature
2013-01 | Journal article
Part of ISSN: 0028-0836
Contributors: Morgan Sheng; Roberto Malinow; Richard Huganir
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Caspases in synaptic plasticity

Molecular Brain
2012 | Journal article
Part of ISSN: 1756-6606
Contributors: Zheng Li; Morgan Sheng
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Caspase-3 in the central nervous system: beyond apoptosis

Trends in Neurosciences
2012-11 | Journal article
Part of ISSN: 0166-2236
Contributors: Marcello D’Amelio; Morgan Sheng; Francesco Cecconi
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

GKAP orchestrates activity-dependent postsynaptic protein remodeling and homeostatic scaling

Nature Neuroscience
2012-11-11 | Journal article
Part of ISSN: 1097-6256
Contributors: Seung Min Shin; Nanyan Zhang; Jonathan Hansen; Nashaat Z Gerges; Daniel T S Pak; Morgan Sheng; Sang H Lee
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Synaptic structure and function

Current Opinion in Neurobiology
2012-06 | Journal article
Part of ISSN: 0959-4388
Contributors: Antoine Triller; Morgan Sheng
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Synapses and Alzheimer's Disease

Cold Spring Harbor Perspectives in Biology
2012-04-04 | Journal article
Part of ISSN: 1943-0264
Contributors: M. Sheng; B. L. Sabatini; T. C. Sudhof
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

NMDA receptors and BAX are essential for Aβ impairment of LTP

Scientific Reports
2012-01 | Journal article
Part of ISSN: 2045-2322
Contributors: Kimberly Moore Olsen; Morgan Sheng
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Communication Impairments in Mice Lacking Shank1: Reduced Levels of Ultrasonic Vocalizations and Scent Marking Behavior

PLoS ONE
2011-06-09 | Journal article
Part of ISSN: 1932-6203
Contributors: Markus Wöhr; Florence I. Roullet; Albert Y. Hung; Morgan Sheng; Jacqueline N. Crawley; Wim E. Crusio
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior

Molecular Psychiatry
2011-04-05 | Journal article
Part of ISSN: 1359-4184
Contributors: M Carlén; K Meletis; J H Siegle; J A Cardin; K Futai; D Vierling-Claassen; C Rühlmann; S R Jones; K Deisseroth; M Sheng et al.
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Sociability and motor functions in Shank1 mutant mice

Brain Research
2011-03 | Journal article
Part of ISSN: 0006-8993
Contributors: Jill L. Silverman; Sarah M. Turner; Charlotte L. Barkan; Seda S. Tolu; Roheeni Saxena; Albert Y. Hung; Morgan Sheng; Jacqueline N. Crawley
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Deconstruction for Reconstruction: The Role of Proteolysis in Neural Plasticity and Disease

Neuron
2011-01 | Journal article
Part of ISSN: 0896-6273
Contributors: Baris Bingol; Morgan Sheng
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

MINK and TNIK Differentially Act on Rap2-Mediated Signal Transduction to Regulate Neuronal Structure and AMPA Receptor Function

Journal of Neuroscience
2010-11-03 | Journal article
Part of ISSN: 0270-6474
Contributors: N. K. Hussain; H. Hsin; R. L. Huganir; M. Sheng
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132

Neuron
2010-10 | Journal article
Part of ISSN: 0896-6273
Contributors: Dieter Edbauer; Joel R. Neilson; Kelly A. Foster; Chi-Fong Wang; Daniel P. Seeburg; Matthew N. Batterton; Tomoko Tada; Bridget M. Dolan; Phillip A. Sharp; Morgan Sheng
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search

Muscarinic receptors induce LTD of NMDAR EPSCs via a mechanism involving hippocalcin, AP2 and PSD-95

Nature Neuroscience
2010-09 | Journal article
Part of ISSN: 1097-6256
Contributors: Jihoon Jo; Gi Hoon Son; Bryony L Winters; Myung Jong Kim; Daniel J Whitcomb; Bryony A Dickinson; Youn-Bok Lee; Kensuke Futai; Mascia Amici; Morgan Sheng et al.
Source: Self-asserted source
Morgan Sheng via Crossref Metadata Search
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Page 1 of 4

Peer review (3 reviews for 2 publications/grants)

Review activity for Nature neuroscience. (2)
Review activity for Neuron. (1)