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Works (16)

Challenges and compromises: Predicting unbound antibody structures with deep learning

Current Opinion in Structural Biology
2025-02 | Journal article
Contributors: Alexander Greenshields-Watson; Odysseas Vavourakis; Fabian C. Spoendlin; Matteo Cagiada; Charlotte M. Deane
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Crossref

PLAbDab-nano: a database of camelid and shark nanobodies from patents and literature

Nucleic Acids Research
2025-01-06 | Journal article
Contributors: Gemma L Gordon; Alexander Greenshields-Watson; Parth Agarwal; Ashley Wong; Fergus Boyles; Alissa Hummer; Ana G Lujan Hernandez; Charlotte M Deane
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Crossref

The Observed T Cell Receptor Space database enables paired-chain repertoire mining, coherence analysis, and language modeling

Cell Reports
2024-09 | Journal article
Part of ISSN: 2211-1247
Contributors: Matthew Raybould; Alexander Greenshields-Watson; Parth Agarwal; Broncio Aguilar-Sanjuan; Tobias H. Olsen; Oliver M. Turnbull; Nele P. Quast; Charlotte Deane
Source: Self-asserted source
Alexander Greenshields-Watson

Tebentafusp Induces a T-Cell–Driven Rash in Melanocyte-Bearing Skin as an Adverse Event Consistent with the Mechanism of Action

Journal of Investigative Dermatology
2024-07 | Journal article
Contributors: Jessica C. Hassel; Sarah Stanhope; Alexander Greenshields-Watson; Devayani Machiraju; Alexander Enk; Christopher Holland; Shaad E. Abdullah; Adel Benlahrech; Marlana Orloff; Paul Nathan et al.
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Crossref

PLAbDab-nano: a database of camelid and shark nanobodies from patents and literature

2024-07-23 | Preprint
Contributors: Gemma L. Gordon; Alexander Greenshields-Watson; Parth Agarwal; Ashley Wong; Fergus Boyles; Alissa Hummer; Ana G. Lujan Hernandez; Charlotte M. Deane
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Crossref

The Observed T cell receptor Space database enables paired-chain repertoire mining, coherence analysis and language modelling

2024-05-21 | Preprint
Contributors: Matthew I. J. Raybould; Alexander Greenshields-Watson; Parth Agarwal; Broncio Aguilar-Sanjuan; Tobias H. Olsen; Oliver M. Turnbull; Nele P. Quast; Charlotte M. Deane
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Crossref

Investigating the ability of deep learning-based structure prediction to extrapolate and/or enrich the set of antibody CDR canonical forms

2023-12-09 | Preprint
Contributors: Alexander Greenshields-Watson; Brennan Abanades; Charlotte M Deane
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Crossref

Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4<sup>+</sup> T cell immunity.

Cell reports
2023-07-19 | Journal article
Contributors: Chen Y; Mason GH; Scourfield DO; Greenshields-Watson A; Haigh TA; Andrew Sewell; Long HM; Gallimore AM; Pierre J. Rizkallah; Bruce J. MacLachlan et al.
Source: Self-asserted source
Alexander Greenshields-Watson

Molecular characterization of HLA class II binding to the LAG-3 T cell co-inhibitory receptor.

European journal of immunology
2020-10-09 | Journal article
Contributors: Bruce J. MacLachlan; Georgina H Mason ; Greenshields-Watson A; Triebel F; Awen Gallimore; David Cole; Godkin A
Source: Self-asserted source
Alexander Greenshields-Watson

Immune Remodeling of the Extracellular Matrix Drives Loss of Cancer Stem Cells and Tumor Rejection.

Cancer immunology research
2020-10-06 | Journal article
Contributors: Ana Pires; Greenshields-Watson A; Jones E; Smart K; Sarah Lauder; Somerville M; Milutinovic S; Kendrick H; James Hindley; French R et al.
Source: Self-asserted source
Alexander Greenshields-Watson

CD4<sup>+</sup> T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features.

Cell reports
2020-07-01 | Journal article
Contributors: Greenshields-Watson A; Attaf M; Bruce J. MacLachlan; Whalley T; Rius C; Wall A; Lloyd A; Hughes H; Kathryn Strange; Georgina H Mason et al.
Source: Self-asserted source
Alexander Greenshields-Watson

VDJdb in 2019: database extension, new analysis infrastructure and a T-cell receptor motif compendium.

Nucleic acids research
2020-01-01 | Journal article
Contributors: Bagaev DV; Vroomans RMA; Jerome Samir; Stervbo U; Rius C; Dolton G; Greenshields-Watson A; Attaf M; Egorov ES; Ivan Zvyagin et al.
Source: Self-asserted source
Alexander Greenshields-Watson

Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope

Journal of Biological Chemistry
2019-12 | Journal article
Contributors: Bruce J. MacLachlan; Garry Dolton; Athanasios Papakyriakou; Alexander Greenshields-Watson; Georgina H. Mason; Andrea Schauenburg; Matthieu Besneux; Barbara Szomolay; Tim Elliott; Andrew K. Sewell et al.
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Crossref

The nature of the human T cell response to the cancer antigen 5T4 is determined by the balance of regulatory and inflammatory T cells of the same antigen-specificity: implications for vaccine design

Cancer Immunology, Immunotherapy
2019-02-07 | Journal article
Contributors: Matthieu Besneux; Alexander Greenshields-Watson; Martin J. Scurr; Bruce J. MacLachlan; Adam Christian; Michael M. Davies; Rachel Hargest; Simon Phillips; Andrew Godkin; Awen Gallimore
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Crossref

Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions

2018-09-03 | Other
Contributors: Alexander T. Baker; Alexander Greenshields-Watson; Lynda Coughlan; James A. Davies; Hanni Uusi-Kerttula; David K. Cole; Pierre J. Rizkallah; Alan L. Parker
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Crossref

T-cell libraries allow simple parallel generation of multiple peptide-specific human T-cell clones.

Journal of immunological methods
2016-01-28 | Journal article
Contributors: Theaker SM; Rius C; Greenshields-Watson A; Lloyd A; Trimby A; Anna Fuller; John Miles; David Cole; Peakman M; Andrew Sewell et al.
Source: Self-asserted source
Alexander Greenshields-Watson

Peer review (1 review for 1 publication/grant)

Review activity for Cell systems. (1)