Personal information

Spain

Activities

Employment (1)

Centro de Investigación del Cáncer: Salamanca, Salamanca, ES

2014-09-16 to present | Postdoctoral researcher (Laboratory 01)
Employment
Source: Self-asserted source
Rosula Garcia Navas

Education and qualifications (3)

Universidad Nebrija: Madrid, ES

2002-03-01 to 2023-02-23 | Máster en Formación del Profesorado de ESO y Bachillerato, FP y Enseñanza de Idiomas (Educación)
Education
Source: Self-asserted source
Rosula Garcia Navas

Universidad de Salamanca: Salamanca, Salamanca, ES

2005-10-01 to 2014-01-24 | PhD (Biology)
Education
Source: Self-asserted source
Rosula Garcia Navas

Universidad Simón Bolívar: Caracas, VE

1996-09-10 to 2002-05-23 | Biology (Biology)
Education
Source: Self-asserted source
Rosula Garcia Navas

Works (23)

Pharmacological SOS1 inhibitor BI-3406 demonstratesin vivoanti-tumor activity comparable to SOS1 genetic ablation in KRAS mutant tumors

2024-09-22 | Preprint
Contributors: Fernando C. Baltanas; Maximilian Kramer-Drauberg; Rósula Garcia-Navas; Enrico Patrucco; Ettore Petrini; Heribert Arnhof; Andrea Olarte-San Juan; Pablo Rodríguez-Ramos; Javier Borrajo; Nuria Calzada et al.
Source: check_circle
Crossref

Combined HRAS and NRAS ablation induces a RASopathy phenotype in mice

Cell Communication and Signaling
2024-06-17 | Journal article
Part of ISSN: 1478-811X
Contributors: Rocío Fuentes-Mateos; Rósula García-Navas; Cristina Fernández-Infante; Luis Hernández-Cano; Nuria Calzada-Nieto; Andrea Olarte-San Juan; Carmen Guerrero; Eugenio Santos; Alberto Fernández-Medarde
Source: Self-asserted source
Rosula Garcia Navas

Critical requirement of SOS1 for tumor development and microenvironment modulation in KRASG12D-driven lung adenocarcinoma

Nature Communications
2023-09-20 | Journal article
Part of ISSN: 2041-1723
Contributors: FERNANDO C. BALTANAS; Rósula García-Navas; Pablo Rodríguez-Ramos; Nuria Calzada; Cristina Cuesta; Javier Borrajo; Rocío Fuentes Mateos; Andrea Olarte-San Juan; Nerea Hongfen Vidaña Bedera; Esther Castellano Sanchez et al.
Source: Self-asserted source
Rosula Garcia Navas

Antenatal N-acetylcysteine antioxidant therapy relieves lung oxidative stress and related perinatal lethality in HRas/NRas double-null mutant mice

Research Square
2022 | Other
EID:

2-s2.0-85167492991

Contributors: Fuentes-Mateos, R.; García-Navas, R.; Calzada, N.; Santos, E.; Fernández-Medarde, A.
Source: Self-asserted source
Rosula Garcia Navas via Scopus - Elsevier

Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors

Oncogene
2022-12-07 | Journal article
Part of ISSN: 0950-9232
Part of ISSN: 1476-5594
Contributors: Rosula Garcia Navas; Laura Clavaín; Isabel Fernandez-Pisonero; Nieves Movilla; L. Francisco Lorenzo-Martín; Blanca Nieto; ANTONIO ABAD; Rósula García-Navas; Clara Llorente-González; Manuel Sanchez-Martin et al.
Source: Self-asserted source
Rosula Garcia Navas

Critical Requirement of SOS1 for Development of BCR/ABL-Driven Chronic Myelogenous Leukemia

Cancers
2022-08-11 | Journal article
Contributors: Carmela Gómez; Rósula Garcia-Navas; Fernando C. Baltanás; Rocío Fuentes-Mateos; Alberto Fernández-Medarde; Nuria Calzada; Eugenio Santos
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Crossref
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Anthraquinones as Inhibitors of SOS RAS-GEF Activity

Biomolecules
2021-07-30 | Journal article
Contributors: Alberto Fernández-Medarde; Rocío Fuentes-Mateos; Rósula García-Navas; Andrea Olarte-San Juan; José María Sánchez-López; Antonio Fernández-Medarde; Eugenio Santos
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Crossref

SOS2 Comes to the Fore: Differential Functionalities in Physiology and Pathology

International Journal of Molecular Sciences
2021-06-21 | Journal article
Contributors: Fernando C. Baltanás; Rósula García-Navas; Eugenio Santos
Source: check_circle
Crossref

Neutrophils drive endoplasmic reticulum stress-mediated apoptosis in cancer cells through arginase-1 release.

Scientific reports
2021-06-15 | Journal article
Contributors: García-Navas R; Gajate C; Mollinedo F
Source: Self-asserted source
Rosula Garcia Navas

Critical requirement of SOS1 RAS-GEF function for mitochondrial dynamics, metabolism, and redox homeostasis.

Oncogene
2021-06-12 | Journal article
Contributors: García-Navas R; Liceras-Boillos P; Gómez C; FERNANDO C. BALTANAS; Calzada N; Cristina Nuevo-Tapioles; Jose Manuel Cuezva Marcos; Eugenio Santos
Source: Self-asserted source
Rosula Garcia Navas

Functional Specificity of the Members of the Sos Family of Ras-GEF Activators: Novel Role of Sos2 in Control of Epidermal Stem Cell Homeostasis

Cancers
2021-04-29 | Journal article
Contributors: Fernando C. Baltanás; Cynthia Mucientes-Valdivieso; L. Francisco Lorenzo-Martín; Natalia Fernández-Parejo; Rósula García-Navas; Carmen Segrelles; Nuria Calzada; Rocío Fuentes-Mateos; Jesús M. Paramio; Xosé R. Bustelo et al.
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Crossref
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Differential Role of the RasGEFs Sos1 and Sos2 in Mouse Skin Homeostasis and Carcinogenesis.

Molecular and cellular biology
2018-07-30 | Journal article
Contributors: Liceras-Boillos P; David Jimeno; García-Navas R; L. Francisco Lorenzo-Martín; Menacho-Marquez M; Segrelles C; Gómez C; Calzada N; Rocío Fuentes Mateos; Jesus M Paramio et al.
Source: Self-asserted source
Rosula Garcia Navas
grade
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Ras-GRF2 regulates nestin-positive stem cell density and onset of differentiation during adult neurogenesis in the mouse dentate gyrus.

Molecular and cellular neurosciences
2017-09-28 | Journal article
Contributors: Gómez C; David Jimeno; Fernández-Medarde A; García-Navas R; Calzada N; Santos E
Source: Self-asserted source
Rosula Garcia Navas
grade
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Sos1 disruption impairs cellular proliferation and viability through an increase in mitochondrial oxidative stress in primary MEFs.

Oncogene
2016-05-09 | Journal article
Contributors: Liceras-Boillos P; García-Navas R; Ginel-Picardo A; Anta B; Martin Perez-Andres; Concepcion Lillo; Gómez C; David Jimeno; Fernández-Medarde A; FERNANDO C. BALTANAS et al.
Source: Self-asserted source
Rosula Garcia Navas
grade
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Arginase activity and CD3ζ expression after major surgery

Intensive Care Medicine
2015 | Journal article
EID:

2-s2.0-84939935138

Part of ISSN: 14321238 03424642
Contributors: Palomero Rodríguez, M.Á.; García Navas, R.; Laporta Báez, Y.; de Vicente Sánchez, J.; Moyano Maza, J.C.; Rodríguez López, J.M.; Sánchez Conde, M.P.; Mollinedo, F.
Source: Self-asserted source
Rosula Garcia Navas via Scopus - Elsevier
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Arginase as a new concern in blood transfusion

Blood Transfusion
2014 | Journal article
EID:

2-s2.0-84883753176

Part of ISSN: 17232007
Contributors: Mollinedo, F.; Palomero-Rodríguez, M.A.; Sánchez-Conde, P.; Garcia-Navas, R.; Laporta-Báez, Y.; De Vicente-Sánchez, J.; Suarez-Gonzalo, L.
Source: Self-asserted source
Rosula Garcia Navas via Scopus - Elsevier
grade
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Endowing indole-based tubulin inhibitors with an anchor for derivatization: Highly potent 3-substituted indolephenstatins and indoleisocombretastatins

Journal of Medicinal Chemistry
2013 | Journal article
EID:

2-s2.0-84876236530

Part of ISSN: 00222623 15204804
Contributors: Álvarez, R.; Puebla, P.; Díaz, J.F.; Bento, A.C.; García-Navas, R.; De La Iglesia-Vicente, J.; Mollinedo, F.; Andreu, J.M.; Medarde, M.; Peláez, R.
Source: Self-asserted source
Rosula Garcia Navas via Scopus - Elsevier
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Antitumor activity of new enantiopure pybox-ruthenium complexes.

Dalton transactions (Cambridge, England : 2003)
2013-08-08 | Journal article
Contributors: Menéndez-Pedregal E; Díez J; Ángel Manteca Fernández; Sánchez J; Bento AC; García-Navas R; Mollinedo F; Gamasa MP; Lastra E
Source: Self-asserted source
Rosula Garcia Navas
grade
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Depletion of L-arginine induces autophagy as a cytoprotective response to endoplasmic reticulum stress in human T lymphocytes

Autophagy
2012 | Journal article
EID:

2-s2.0-84869486265

Part of ISSN: 15548635 15548627
Contributors: García-Navas, R.; Munder, M.; Mollinedo, F.
Source: Self-asserted source
Rosula Garcia Navas via Scopus - Elsevier
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Relationship between arginase activity and the storage time of packed red blood cells,Relación entre la actividad arginasa y el tiempo de conservación de los concentrados de hematíes

Revista Espanola de Anestesiologia y Reanimacion
2012 | Journal article
EID:

2-s2.0-84868289979

Part of ISSN: 00349356
Contributors: Palomero Rodríguez, M.A.; García Navas, R.; Laporta Báez, Y.; Al Kassam Martínez, D.; de Vicente Sánchez, J.; Cacharro Moras, L.M.; Sánchez Conde, P.; Mollinedo, F.; Muriel Villoria, C.
Source: Self-asserted source
Rosula Garcia Navas via Scopus - Elsevier
grade
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The metalloprotease ADAM8 is associated with and regulates the function of the adhesion receptor PSGL-1 through ERM proteins

European Journal of Immunology
2011 | Journal article
EID:

2-s2.0-82255194221

Part of ISSN: 00142980 15214141
Contributors: Domínguez-Luis, M.; Lamana, A.; Vazquez, J.; García-Navas, R.; Mollinedo, F.; Sánchez-Madrid, F.; Díaz-González, F.; Urzainqui, A.
Source: Self-asserted source
Rosula Garcia Navas via Scopus - Elsevier
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Antitumor activity of new hydridotris(pyrazolyl)borate ruthenium(II) complexes containing the phosphanes PTA and 1-CH3-PTA.

Dalton transactions (Cambridge, England : 2003)
2010-09-30 | Journal article
Contributors: Almudena García-Fernández; Díez J; Manteca A; Sánchez J; García-Navas R; Sierra BG; Mollinedo F; Gamasa MP; Lastra E
Source: Self-asserted source
Rosula Garcia Navas
grade
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Mycobacterium tuberculosis transporter MmpL7 is a potential substrate for kinase PknD

Biochemical and Biophysical Research Communications
2006 | Journal article
EID:

2-s2.0-33746680377

Part of ISSN: 0006291X 10902104
Contributors: Pérez, J.; Garcia, R.; Bach, H.; de Waard, J.H.; Jacobs Jr., W.R.; Av-Gay, Y.; Bubis, J.; Takiff, H.E.
Source: Self-asserted source
Rosula Garcia Navas via Scopus - Elsevier
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Peer review (2 reviews for 2 publications/grants)

Review activity for European journal of cell biology. (1)
Review activity for Molecular biology reports. (1)