Personal information

Websites & social links

The Vogel Group
SDU profile page

Other IDs

Web of Science Researcher ID: DYC-4832-2022
Scopus Author ID: 14066157700

Keywords

Nucleic Acid Chemistry, Liposomes, Organic Synthesis, RNA World, Biopolymer conjugates

Countries

Denmark

Activities

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Employment (3)

University of Southern Denmark: Odense, DK

2019-07-01 to present | Assistant Professor (Department of Physics, Chemistry and Pharmacy)
Employment
Source: Self-asserted source
Philipp M. G. Löffler

University of Soutern Denmark: Odense, DK

2014-09-01 to present | Postdoc. at the Biomolecular Nanoscale Engineering Centerr (Physics, Chemistry and Pharmacy)
Employment
Source: Self-asserted source
Philipp M. G. Löffler

SDU: N/A, DK

2022-10-15
Employment
Source: check_circle
University of Southern Denmark

Education and qualifications (2)

University of Southern Denmark: Odense, DK

2011-02-15 to 2014-06-24 | Ph.D. Chemistry (Physics, Chemistry and Pharmacy)
Education
Source: Self-asserted source
Philipp M. G. Löffler

University of Southern Denmark: Odense, DK

2008-09-01 to 2010-12-01 | M.Sc. Nanobioscience (Physics, Chemistry and Pharmacy)
Education
Source: Self-asserted source
Philipp M. G. Löffler

Works (32)

Programmable RNA Loading of Extracellular Vesicles with Toehold-Release Purification

Journal of the American Chemical Society
2024-05-08 | Journal article | Author
DOI: 10.1021/jacs.3c13123
SOURCE-WORK-ID:

75d732b8-5ec3-4695-8a69-40ea4fb8271a

PMID: 38669207
EID:

2-s2.0-85191787511
Contributors: Mette Galsgaard Malle; Ping Song; Philipp M. G. Löffler; Nazmie Kalisi; Yan Yan; Julián Valero; Stefan Vogel; Jørgen Kjems
Source: check_circle
University of Southern Denmark
grade
Preferred source (of 2)‎

Label-free observation of DNA-encoded liposome fusion by surface plasmon resonance

Chemical Communications
2023 | Journal article | Author
DOI: 10.1039/d3cc02793g
SOURCE-WORK-ID:

eee990a1-f863-41b1-aa40-e53d0ece93ab

EID:

2-s2.0-85168566080

PMID: 37566388
Contributors: Philipp M. G. Löffler; Nikolaj Alexander Risgaard; Bettina L. Svendsen; Katrine A. Jepsen; Alexander Rabe; Stefan Vogel
Source: check_circle
University of Southern Denmark
grade
Preferred source (of 2)‎

DNA-Programmed Lipid Nanoreactors for Synthesis of Carbohydrate Mimetics by Fusion of Aqueous Sub-attoliter Compartments

Journal of the American Chemical Society
2023-08-24 | Journal article | Author
DOI: 10.1021/jacs.3c04093
SOURCE-WORK-ID:

43d42faa-128a-43e4-a00f-85d0d0ea2381

EID:

2-s2.0-85169907012

PMID: 37619973
Contributors: Xinwei Tian; Nikolaj Alexander Risgaard; Philipp M. G. Löffler; Stefan Vogel
Source: check_circle
University of Southern Denmark
grade
Preferred source (of 2)‎

Development of a Molecular Aptamer Beacon Applied to Magnetic-Assisted RNA Extraction for Detection of Dengue and Zika Viruses Using Clinical Samples

International Journal of Molecular Sciences
2022-11-10 | Journal article
DOI: 10.3390/ijms232213866
Contributors: Amanda Gabrielle da Silva; Luiz Ricardo Goulart; Philipp Löffler; Christian Code; Adriana Freitas Neves
Source: check_circle
Crossref
grade
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Photosensitization of pancreatic cancer cells by cationic alkyl-porphyrins in free form or engrafted into POPC liposomes

Journal of Photochemistry and Photobiology B: Biology
2022-06 | Journal article | Author
DOI: 10.1016/j.jphotobiol.2022.112449
SOURCE-WORK-ID:

0fbf4570-8079-4f09-848c-d08b0ab34c15

EID:

2-s2.0-85129066472

PMID: 35504235
Contributors: Eros Di Giorgio; Annalisa Ferino; Himanshi Choudhary; Philipp M. G. Löffler; Francesca D'Este; Valentina Rapozzi; Alexander Tikhomirov; Andrey Shchekotikhin; Stefan Vogel; Luigi E. Xodo
Source: check_circle
University of Southern Denmark

Single-particle combinatorial multiplexed liposome fusion mediated by DNA

Nature Chemistry
2022-05 | Journal article
DOI: 10.1038/s41557-022-00912-5
Contributors: Mette Galsgaard Malle; Philipp M. G. Löffler; Søren S.-R. Bohr; Magnus Berg Sletfjerding; Nikolaj Alexander Risgaard; Simon Bo Jensen; Min Zhang; Per Hedegård; Stefan Vogel; Nikos S. Hatzakis
Source: check_circle
Crossref
grade
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Targeting SARS-CoV-2 spike protein by stapled hACE2 peptides

Chemical Communications
2021 | Journal article | Author
DOI: 10.1039/D0CC08387A
SOURCE-WORK-ID:

15d33c7e-fdf3-48f9-b220-b36fbcc6bc7d

EID:

2-s2.0-85103436148
Contributors: Marijn Maas; Jordi C. J. Hintzen; Philipp M. G. Löffler; Jasmin Mecinovic
Source: check_circle
University of Southern Denmark
grade
Preferred source (of 2)‎

Single particle combinatorial multiplexed liposome fusion mediated by DNA

2021-01-20 | Preprint
DOI: 10.1101/2021.01.19.427313
Contributors: Mette Galsgaard Malle; Philipp M. G. Löffler; Søren S.-R. Bohr; Magnus Berg Sletfjerding; Nikolaj Alexander Risgaard; Simon Bo Jensen; Min Zhang; Per Hedegaard; Stefan Vogel; Nikos S. Hatzakis
Source: check_circle
Crossref

DNA-Mediated Liposome Fusion Observed by Fluorescence Spectrometry

Nucleic Acid Detection and Structural Investigations
2020 | Book chapter | Author
DOI: 10.1007/978-1-0716-0138-9_9
SOURCE-WORK-ID:

4ee25a58-81ad-481a-b0ec-9dbab2ca0693

EID:

2-s2.0-85074341693

PMID: 31667766
Part of ISBN: 978-1-0716-0138-9
Part of ISBN: 978-1-0716-0137-2
Contributors: Philipp M. G. Löffler; Oliver Ries; Stefan Vogel
Source: check_circle
University of Southern Denmark

Lipid-Modified Peptide Nucleic Acids

Peptide Nucleic Acids
2020 | Book chapter | Author
DOI: 10.1007/978-1-0716-0243-0_5
SOURCE-WORK-ID:

8b126417-7bb6-48be-8ae9-f4aa2acf4b6c

EID:

2-s2.0-85079912672

PMID: 32088865
Part of ISBN: 978-1-0716-0243-0
Part of ISBN: 978-1-0716-0242-3
Contributors: Philipp M. G. Löffler; Alexander Rabe; Stefan Vogel
Source: check_circle
University of Southern Denmark

Lipidated Polyaza Crown Ethers as Membrane Anchors for DNA-Controlled Content Mixing between Liposomes

Scientific Reports
2019-09-25 | Journal article | Author
DOI: 10.1038/s41598-019-49862-y
SOURCE-WORK-ID:

75475aca-366a-4932-8822-c5b84ba2e631

EID:

2-s2.0-85072683768

PMID: 31554826
Contributors: Philipp M. G. Löffler; Anders Højgaard Hansen; Oliver Ries; Ulla Jakobsen; Alexander Rabe; Kristian T. Sørensen; Kasper Glud; Stefan Vogel
Source: check_circle
University of Southern Denmark
grade
Preferred source (of 2)‎

Efficient liposome fusion mediated by lipid-nucleic acid conjugates

Organic & Biomolecular Chemistry
2017 | Journal article | Author
DOI: 10.1039/c7ob01939d
SOURCE-WORK-ID:

49f2719a-9675-4379-be9f-5e63064ba8ec

PMID: 29043358
EID:

2-s2.0-85032723012
Contributors: O Ries; Philipp M. G. Löffler; A Rabe; J J Malavan; Stefan Vogel
Source: check_circle
University of Southern Denmark
grade
Preferred source (of 2)‎

Fusion von Liposomen in einer DNA‐programmierten Kaskade

Angewandte Chemie
2017 | Journal article | Author
DOI: 10.1002/ange.201703243
SOURCE-WORK-ID:

334c3a31-ce6e-40be-85ed-bd731c63674a
Contributors: Philipp M. G. Löffler; Oliver Ries; Alexander Rabe; Anders Hauge Okholm; Rasmus P Thomsen; Jørgen Kjems; Stefan Vogel
Source: check_circle
University of Southern Denmark

Programmable fusion of liposomes mediated by lipidated PNA

Chemical Communications
2017 | Journal article | Author
DOI: 10.1039/c7cc06058k
SOURCE-WORK-ID:

9e2ae5da-87ad-4bc8-991e-f55d3101d51c

PMID: 29044250
EID:

2-s2.0-85032632422
Contributors: A Rabe; Philipp M. G. Löffler; O Ries; Stefan Vogel
Source: check_circle
University of Southern Denmark
grade
Preferred source (of 2)‎

Synthesis of Lipophilic Guanine N-9 Derivatives

Bioconjugate Chemistry
2017 | Journal article | Author
DOI: 10.1021/acs.bioconjchem.7b00228
SOURCE-WORK-ID:

a060b061-ea91-47f8-8fa9-bf1827451986

PMID: 28587449
EID:

2-s2.0-85025147857
Contributors: Michael C Wamberg; Pernille L Pedersen; Philipp M. G. Löffler; Anders N Albertsen; Sarah E Maurer; Kent A Nielsen; Pierre-Alain Monnard
Source: check_circle
University of Southern Denmark
grade
Preferred source (of 2)‎

A DNA-programmed liposome fusion cascade

Angewandte Chemie International Edition
2017-10-16 | Journal article | Author
DOI: 10.1002/anie.201703243
SOURCE-WORK-ID:

a93a3159-327f-437c-bbb7-71f2c27de47a

PMID: 28598002
EID:

2-s2.0-85028576102
Contributors: Philipp M. G. Löffler; Oliver Ries; Alexander Rabe; Anders Hauge Okholm; Rasmus P Thomsen; Jørgen Kjems; Stefan Vogel
Source: check_circle
University of Southern Denmark
grade
Preferred source (of 2)‎

Optimizing DNA-controlled Membrane Fusion - Efficient Lipid and Content Mixing

Nucleic acids Chemistry & Biology 7th Cambridge Symposium, Cambridge, United Kingdom, 03/09/2017
2017-09 | Conference poster | Author
SOURCE-WORK-ID:

f1a639ba-8e76-4a71-9d52-0ae2beec2845
Contributors: Philipp M. G. Löffler; Stefan Vogel
Source: check_circle
University of Southern Denmark

Lipid membrane anchors in Lipid-Nucleic acid (LiNA) conjugates for liposome fusion

Danish Chemical Society Meeting 2016, Odense, Denmark, 09/06/2016
2016-06-09 | Conference poster | Author
SOURCE-WORK-ID:

857f1890-7c19-4f2a-800c-3ab274a47777
Contributors: Philipp M. G. Löffler; Oliver Ries
Source: check_circle
University of Southern Denmark

Convenient synthesis and application of versatile nucleic acid lipid membrane anchors in the assembly and fusion of liposomes.

Organic & Biomolecular Chemistry
2015-10 | Journal article
DOI: 10.1039/c5ob01207d
PMID: 26264076
Source: Self-asserted source
Philipp M. G. Löffler
grade
Preferred source (of 3)‎

Non-enzymatic nucleic acid replication supported by self-assembled interfaces

2014 | Dissertation or Thesis | Author
SOURCE-WORK-ID:

04348f55-7dde-4fee-8510-741b688c7a70
Contributors: Philipp M. G. Löffler
Source: check_circle
University of Southern Denmark

Bottom–Up Protocell Design: Gaining Insights in the Emergence of Complex Functions

Evolutionary Biology: Exobiology and Evolutionary Mechanisms
2013 | Other
DOI: 10.1007/978-3-642-38212-3_6
Contributors: Rafał Wieczorek; Michael C. Wamberg; Anders N. Albertsen; Philipp M. G. Löffler; Pierre-Alain Monnard
Source: Self-asserted source
Philipp M. G. Löffler via Crossref Metadata Search
grade
Preferred source (of 2)‎

Sliding over the blocks in enzyme-free RNA copying--one-pot primer extension in ice.

2013 | Journal article
DOI: 10.1371/journal.pone.0075617
PMID: 24058695
PMC: PMC3776762
Contributors: Löffler PM; Groen J; Dörr M; Monnard PA
Source: Self-asserted source
Philipp M. G. Löffler via Europe PubMed Central
grade
Preferred source (of 2)‎

Towards protocell embedded replication of nucleic acids

Artificial Life 13: Proceedings of the Thirteenth International Conference on the Synthesis and Simulation of Living Systems
2012 | Conference paper | Author
SOURCE-WORK-ID:

422fbc66-9c6d-4137-ba99-b4b6ed596676
Contributors: Philipp M. G. Löffler; Rafal Wieczorek; Michael Chr. Wamberg; Mark Dörr; Pernille Lykke Pedersen; Carsten Svaneborg; Harold Fellermann; Joseph B. Edson; Jonathan Cape; Hans-Joachim Ziock et al.
Source: check_circle
University of Southern Denmark

Non-enzymatic Polymerization of Nucleic Acids from Monomers: Monomer Self- Condensation and Template-Directed Reactions

Current Organic Synthesis
2012-11-01 | Journal article
DOI: 10.2174/157017912803901691
Source: Self-asserted source
Philipp M. G. Löffler
grade
Preferred source (of 3)‎

Bottom up assembly of minimal life

6th Danish Conference on Biotechnology and Molecular Biology: Synthetic Biology and Cell Factories, Vejle, Denmark, 26/05/2011
2011 | Conference abstract | Author
SOURCE-WORK-ID:

e1325655-8518-4d8f-b7d5-e54f86607630
Contributors: Steen Rasmussen; Pierre-Alain Monnard; Martin Hanczyc; Anders N. Albertsen; Eva Bönzli; Filippo Caschera; Mark Dörr; Harold Fellermann; Wendie Hagedorn Jørgensen; Philipp M. G. Löffler et al.
Source: check_circle
University of Southern Denmark

Stable vesicles composed of monocarboxylic or dicarboxylic fatty acids and trimethylammonium amphiphiles.

2011-12 | Journal article
DOI: 10.1021/la203057b
PMID: 21932777
Contributors: Caschera F; Bernardino de la Serna J; Löffler PM; Rasmussen TE; Hanczyc MM; Bagatolli LA; Monnard PA
Source: Self-asserted source
Philipp M. G. Löffler via Europe PubMed Central
grade
Preferred source (of 2)‎

A review of one approach to bottom up assembly of minimal life

Advances in Artificial Life, ECAL 2011: Proceedings of the Eleventh European Conference on the Synthesis and Simulation of Living Systems
2011-08 | Conference paper | Author
SOURCE-WORK-ID:

4ef3fad1-035a-4664-92c7-9ca52a6f4471

Part of ISBN: 978-0-262-29714-1
Contributors: Steen Rasmussen; Pierre-Alain Monnard; Martin Hanczyc; Anders N. Albertsen; Eva Bönzli; Filippo Caschera; Mark Dörr; Harold Fellermann; Wendie Hagedorn Jørgensen; Philipp M. G. Löffler et al.
Source: check_circle
University of Southern Denmark

Eutectic phases in water-ice : an efficient medium for biopolymerization

ISSOL 2011, Montpellier, France, 03/07/2011
2011-07-03 | Conference poster | Author
SOURCE-WORK-ID:

4ecfb212-891c-42b1-a464-2b0ccd6bd2f2
Contributors: Pierre-Alain Monnard; Mark Dörr; Philipp M. G. Löffler; Rafal Wieczorek
Source: check_circle
University of Southern Denmark

Template Directed Oligomer Ligation in Eutectic Phases in Water-Ice

2011-07-03 | Conference poster | Author
SOURCE-WORK-ID:

e9e775a0-184f-42e3-868d-8b42b00a09b2
Contributors: Mark Dörr; Philipp M. G. Löffler; Rafal Wieczorek; Pierre-Alain Monnard
Source: check_circle
University of Southern Denmark

Possible Role of Ice in the Synthesis of Polymeric Compounds

Proceedings of the 12th international conference on Artificial Life
2010 | Book chapter | Author
SOURCE-WORK-ID:

05984d41-bc3d-4363-bd24-f449685f34a6

Part of ISBN: 978-0-262-29075-3
Contributors: Pierre-Alain Monnard; Mark Dörr; Philipp M. G. Löffler
Source: check_circle
University of Southern Denmark

Ethyl 2-(1,2,3,4-tetrahydro-spiro-[carba-zole-3,2'-[1,3]dioxolan]-9-yl)acetate.

2009 | Journal article
DOI: 10.1107/S160053680900748X
PMID: 21582427
PMC: PMC2969037
Contributors: Löffler PM; Ulven T; Bond AD
Source: Self-asserted source
Philipp M. G. Löffler via Europe PubMed Central
grade
Preferred source (of 2)‎

Tetra-μ 2 -acetato-bis({1-[5-(dimethylamino)naphthylsulfonyl]imidazole-κ N 3 }rhodium)( Rh — Rh ) acetonitrile disolvate

Acta Crystallogr Sect E Struct Rep Online
2006-07 | Journal article
DOI: 10.1107/s1600536806025311
Contributors: Philipp M. G. Löffler; Henrik H. Petersen; Signe Skovsgaard; Christine J. McKenzie; Andrew D. Bond
Source: Self-asserted source
Philipp M. G. Löffler via Crossref Metadata Search
grade
Preferred source (of 2)‎
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