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Works (12)

The Antitumor Effect of the DNA Polymerase Alpha Inhibitor ST1926 in Glioblastoma: A Proteomics Approach

International Journal of Molecular Sciences
2023-09-14 | Journal article
DOI: 10.3390/ijms241814069
Contributors: Chirine El-Baba; Zeinab Ayache; Mona Goli; Berthe Hayar; Zeinab Kawtharani; Claudio Pisano; Firas Kobeissy; Yehia Mechref; Nadine Darwiche
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Mannose Inhibits the Pentose Phosphate Pathway in Colorectal Cancer and Enhances Sensitivity to 5-Fluorouracil Therapy

Cancers
2023-04-13 | Journal article
DOI: 10.3390/cancers15082268
Contributors: Sadaf Al Hadeethi; Chirine El-Baba; Khaled Araji; Berthe Hayar; Israa Ahmad Cheikh; Riyad El-Khoury; Julnar Usta; Nadine Darwiche
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Lessons learned from the discovery and development of the sesquiterpene lactones in cancer therapy and prevention

Expert Opinion on Drug Discovery
2022-12-02 | Journal article
DOI: 10.1080/17460441.2023.2147920
Contributors: Israa A. Cheikh; Chirine El-Baba; Ali Youssef; Najat A. Saliba; Akram Ghantous; Nadine Darwiche
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The Pentose Phosphate Pathway in Cancer: Regulation and Therapeutic Opportunities

Chemotherapy
2021 | Journal article
DOI: 10.1159/000519784
Contributors: Noorhan Ghanem; Chirine El-Baba; Khaled Araji; Riyad El-Khoury; Julnar Usta; Nadine Darwiche
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Crossref

Terpenoids’ anti-cancer effects: focus on autophagy

Apoptosis
2021-10 | Journal article
DOI: 10.1007/s10495-021-01684-y
Contributors: Chirine El-Baba; Amro Baassiri; Georges Kiriako; Batoul Dia; Sukayna Fadlallah; Sara Moodad; Nadine Darwiche
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Synthesis of Novel Hybrids of Thymoquinone and Artemisinin with High Activity and Selectivity Against Colon Cancer.

2016-12 | Journal article
DOI: 10.1002/cmdc.201600594
PMID: 27973725
Contributors: Fröhlich T; Ndreshkjana B; Muenzner JK; Reiter C; Hofmeister E; Mederer S; Fatfat M; El-Baba C; Gali-Muhtasib H; Schneider-Stock R et al.
Source: Self-asserted source
Chirine El-Baba via Europe PubMed Central
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Gallotannin is a DNA damaging compound that induces senescence independently of p53 and p21 in human colon cancer cells.

2015-10 | Journal article
DOI: 10.1002/mc.22172
PMID: 24798519
Contributors: Al-Halabi R; Abou Merhi R; Chakilam S; El-Baba C; Hamade E; Di Fazio P; Ocker M; Schneider-Stock R; Gali-Muhtasib H
Source: Self-asserted source
Chirine El-Baba via Europe PubMed Central

Thymoquinone-induced conformational changes of PAK1 interrupt prosurvival MEK-ERK signaling in colorectal cancer.

2014 | Journal article
DOI: 10.1186/1476-4598-13-201
PMID: 25174975
PMC: PMC4158125
Contributors: El-Baba C; Mahadevan V; Fahlbusch FB; Mohan S S; Rau TT; Gali-Muhtasib H; Schneider-Stock R
Source: Self-asserted source
Chirine El-Baba via Europe PubMed Central

Thymoquinone: fifty years of success in the battle against cancer models.

2014-01 | Journal article
DOI: 10.1016/j.drudis.2013.08.021
PMID: 24001594
Contributors: Schneider-Stock R; Fakhoury IH; Zaki AM; El-Baba CO; Gali-Muhtasib HU
Source: Self-asserted source
Chirine El-Baba via Europe PubMed Central

Thymoquinone induces apoptosis in malignant T-cells via generation of ROS.

2013 | Journal article
DOI: 10.2741/e651
PMID: 23277025
Contributors: Dergarabetian EM; Ghattass KI; El-Sitt SB; Al-Mismar RM; El-Baba CO; Itani WS; Melhem NM; El-Hajj HA; Bazarbachi AA; Schneider-Stock R et al.
Source: Self-asserted source
Chirine El-Baba via Europe PubMed Central

Sage components enhance cell death through nuclear factor kappa-B signaling.

2011 | Journal article
DOI: 10.2741/e256
PMID: 21196321
Contributors: Deeb SJ; El-Baba CO; Hassan SB; Larsson RL; Gali-Muhtasib HU
Source: Self-asserted source
Chirine El-Baba via Europe PubMed Central

Absence of mutation in the SLC2A1 gene in a cohort of patients with alternating hemiplegia of childhood (AHC).

2010-12 | Journal article
DOI: 10.1055/s-0031-1271767
PMID: 21445818
Contributors: Vuillaumier-Barrot S; Panagiotakaki E; Le Bizec C; El Baba C; ENRAHs for SME Consortium; Fontaine B; Arzimanoglou A; Seta N; Nicole S
Source: Self-asserted source
Chirine El-Baba via Europe PubMed Central
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