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Scopus Author ID: 56650577300

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Employment (7)

Northumbria University: N/A, GB

Employment
Source: check_circle
Northumbria University

Northumbria University: Newcastle upon Tyne, GB

2022-09-01 to present | Assistant Professor (Applied Biosciences)
Employment
Source: Self-asserted source
Ruchi Shukla

Newcastle University Centre for Cancer: Newcastle upon Tyne, Newcastle upon Tyne, GB

2016-02-01 to 2022-08-31 | Research Fellow
Employment
Source: Self-asserted source
Ruchi Shukla

MRC Human Genetics Unit: Edinburgh, Edinburgh, GB

2013-04 to 2016-01 | Postdoctoral fellow
Employment
Source: Self-asserted source
Ruchi Shukla

University of Edinburgh Roslin Institute: Roslin, Midlothian, GB

2011-08 to 2012-11 | Postdoctoral fellow
Employment
Source: Self-asserted source
Ruchi Shukla

INSERM U1052: Lyon, FR

2010-02 to 2011-03 | Postdoctoral Fellow
Employment
Source: Self-asserted source
Ruchi Shukla

International Agency for Research on Cancer: Lyon, Rhône-Alpes, FR

2007-05 to 2010-01 | Postdoctoral Fellow
Employment
Source: Self-asserted source
Ruchi Shukla

Education and qualifications (1)

National Centre For Cell Science: Pune, Maharashtra, IN

2002-09 to 2007-04 | Ph D
Education
Source: Self-asserted source
Ruchi Shukla

Works (24)

Endogenous retroelement activation is implicated in IFN-α production and anti-CCP autoantibody generation in early Rheumatoid Arthritis

Arthritis and Rheumatism
2024-12-16 | Journal article | Author
DOI: 10.1002/art.43083
SOURCE-WORK-ID:

fed06ebb-b7dd-4b1f-b376-6d3ba7e70367

EID:

2-s2.0-85216557174
Contributors: Faye A. H. Cooles; Gemma Vidal Pedrola; Najib Naamane; Arthur G. Pratt; Ben Barron‐Millar; Amy E. Anderson; Catharien M. U. Hilkens; John Casement; Vincent Bondet; Darragh Duffy et al.
Source: check_circle
Northumbria University

Impact of retrotransposon protein L1 ORF1p expression on oncogenic pathways in hepatocellular carcinoma

British Journal of Cancer
2023-03-30 | Journal article | Author
DOI: 10.1038/s41416-023-02154-9
SOURCE-WORK-ID:

4d649cc5-e4a3-4e7d-90b2-0e71377ce6dc

PMID: 36707636
EID:

2-s2.0-85146946323

WOSUID:

000923130800001
Contributors: Bassier Zadran; Praveen Dhondurao Sudhindar; Daniel Wainwright; Yvonne Bury; Saimir Luli; Rachel Howarth; Misti Vanette McCain; Robyn Watson; Hannah Huet; Fanni Palinkas et al.
Source: check_circle
Northumbria University

Identification of TIAM1 as a Potential Synthetic-Lethal-like Gene in a Defined Subset of Hepatocellular Carcinoma

International Journal of Molecular Sciences
2023-03-28 | Journal article | Author
DOI: 10.3390/ijms24076387
SOURCE-WORK-ID:

e9293f5e-6fdb-4a13-ab07-4c133403e0df

EID:

2-s2.0-85152777698
Contributors: Chalermsin Permtermsin; H. Lalchungnunga; Sirintra Nakjang; John Casement; Laura Frances Ogle; Helen L. Reeves; Gordon Strathdee; Ruchi Shukla; Michael Welsh
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Northumbria University

Sulfatase-2 from Cancer Associated Fibroblasts

Liver Cancer
2022-12-13 | Journal article | Author
DOI: 10.1159/000525375
SOURCE-WORK-ID:

7cf28a49-f515-4b42-aeb1-04a890055efe

EID:

2-s2.0-85143905303
Contributors: Marco Y.W. Zaki; Sari F. Alhasan; Ruchi Shukla; Misti McCain; Maja Laszczewska; Daniel Geh; Gillian L. Patman; Despina Televantou; Anna Whitehead; João P. Maurício et al.
Source: check_circle
Northumbria University
grade
Preferred source (of 2)‎

Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway

Biochemical Journal
2022-10-14 | Journal article | Author
DOI: 10.1042/BCJ20220102
SOURCE-WORK-ID:

d1c3f062-1205-4fa1-80f6-5d7a3ebd600b

EID:

2-s2.0-85139885179

PMID: 36240066
Contributors: Jill E. Hunter; Amy E. Campbell; Nicola L. Hannaway; Scott Kerridge; Saimir Luli; Jacqueline A. Butterworth; Helene Sellier; Reshmi Mukherjee; Nikita Dhillon; Praveen D. Sudhindar et al.
Source: check_circle
Northumbria University

Key features of the environment promoting liver cancer in the absence of cirrhosis

Scientific Reports
2021-12-01 | Journal article | Author
DOI: 10.1038/s41598-021-96076-2
SOURCE-WORK-ID:

a241f8ad-bf47-4ad5-8c8e-7dec17b23f25

EID:

2-s2.0-85113182589

PMID: 34408183
Contributors: Marco Youssef William Zaki; Ahmed Khairallah Mahdi; Gillian Lucinda Patman; Anna Whitehead; João Pais Maurício; Misti Vanette McCain; Despina Televantou; Sameh Abou-Beih; Erik Ramon-Gil; Robyn Watson et al.
Source: check_circle
Northumbria University

HCV Activates Somatic L1 Retrotransposition—A Potential Hepatocarcinogenesis Pathway

Cancers
2021-10 | Journal article | Author
DOI: 10.3390/cancers13205079
Contributors: Praveen Dhondurao Sudhindar; Daniel Wainwright; Santu Saha; Rachel Howarth; Misti McCain; Yvonne Bury; Sweta S. Saha; Stuart McPherson; Helen Reeves; Arvind Patel et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

A PDCD1 Role in the Genetic Predisposition to NAFLD-HCC?

Cancers
2021-03-19 | Journal article | Author
DOI: 10.3390/cancers13061412
SOURCE-WORK-ID:

338ceb49-3aa5-432d-8e03-099be841f5f5

EID:

2-s2.0-85102680921
Contributors: Nardeen Eldafashi; Rebecca Darlay; Ruchi Shukla; Misti Vanette McCain; Robyn Watson; Yang Lin Liu; Nikki McStraw; Moustafa Fathy; Michael Atef Fawzy; Marco Y.W. Zaki et al.
Source: check_circle
Northumbria University

L1 retrotransposition is a common feature of mammalian hepatocarcinogenesis

Genome Research
2018-05 | Journal article | Author
DOI: 10.1101/gr.226993.117
SOURCE-WORK-ID:

4ad3450b-8901-4370-8498-01b638be2b78

EID:

2-s2.0-85046619387

PMID: 29643204
Contributors: Stephanie N. Schauer; Patricia E. Carreira; Ruchi Shukla; Daniel J. Gerhardt; Patricia Gerdes; Francisco J. Sanchez-Luque; Paola Nicoli; Michaela Kindlova; Serena Ghisletti; Alexandre D. Dos Santos et al.
Source: check_circle
Northumbria University

Mutual epithelium-macrophage dependency in liver carcinogenesis mediated by ST18

Hepatology
2017-05 | Journal article | Author
DOI: 10.1002/hep.28942
SOURCE-WORK-ID:

75d71a3e-c224-41c1-a507-cb47a4de10a0

EID:

2-s2.0-85007442882

PMID: 27859418
Contributors: Micol Ravà; Aleco D'Andrea; Mirko Doni; Theresia R. Kress; Renato Ostuni; Valerio Bianchi; Marco J. Morelli; Agnese Collino; Serena Ghisletti; Paola Nicoli et al.
Source: check_circle
Northumbria University

Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells

Nature Communications
2016-01-08 | Journal article | Author
DOI: 10.1038/ncomms10286
SOURCE-WORK-ID:

c1485a6a-1d0e-49b7-9689-e50d10387bfc

EID:

2-s2.0-84953911769

PMID: 26743714
Contributors: Sabine Klawitter; Nina V. Fuchs; Kyle R. Upton; Martin Muñoz-Lopez; Ruchi Shukla; Jichang Wang; Marta Garcia-Cañadas; Cesar Lopez-Ruiz; Daniel J. Gerhardt; Attila Sebe et al.
Source: check_circle
Northumbria University

Endogenous retrotransposition activates oncogenic pathways in hepatocellular carcinoma

Cell
2013-03-28 | Journal article | Author
DOI: 10.1016/j.cell.2013.02.032
SOURCE-WORK-ID:

ec3c7d94-bd95-4abe-b797-4789b226fb5c

EID:

2-s2.0-84875698271

PMID: 23540693
Contributors: Ruchi Shukla; Kyle R. Upton; Martin Muñoz-Lopez; Daniel J. Gerhardt; Malcolm E. Fisher; Thu Nguyen; Paul M. Brennan; J. Kenneth Baillie; Agnese Collino; Serena Ghisletti et al.
Source: check_circle
Northumbria University

Extensive somatic L1 retrotransposition in colorectal tumors

Genome Research
2012-12 | Journal article | Author
DOI: 10.1101/gr.145235.112
SOURCE-WORK-ID:

5a6989eb-902d-4a6a-b28a-2230ca9a7ff0

EID:

2-s2.0-84870482898

PMID: 22968929
Contributors: Szilvia Solyom; Adam D. Ewing; Eric P. Rahrmann; Tara Doucet; Heather H. Nelson; Michael B. Burns; Reuben S. Harris; David F. Sigmon; Alex Casella; Bracha Erlanger et al.
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Northumbria University

Transcriptional regulation of the human tumor suppressor DOK1 by E2F1

Molecular and Cellular Biology
2012-12 | Journal article | Author
DOI: 10.1128/MCB.01050-12
SOURCE-WORK-ID:

9a97745e-474d-46df-8f1e-be75e363d638

EID:

2-s2.0-84871894593

PMID: 23028047
Contributors: Maha Siouda; Jiping Yue; Ruchi Shukla; Sophie Guillermier; Zdenko Herceg; Marion Creveaux; Rosita Accardi; Massimo Tommasino; Bakary S. Sylla
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Northumbria University

Inactivation of the putative suppressor gene DOK1 by promoter hypermethylation in primary human cancers

International Journal of Cancer
2012-06-01 | Journal article | Author
DOI: 10.1002/ijc.26299
SOURCE-WORK-ID:

44c48fab-b421-456a-a129-9d0f487727aa

EID:

2-s2.0-84859162851

PMID: 21796618
Contributors: Amandine Saulnier; Thomas Vaissière; Jiping Yue; Maha Siouda; Marine Malfroy; Rosita Accardi; Marion Creveaux; Sinto Sebastian; Naveed Shahzad; Tarik Gheit et al.
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Northumbria University

Cutaneous human papillomavirus type 38 E7 regulates actin cytoskeleton structure for increasing cell proliferation through CK2 and the eukaryotic elongation factor 1A

Journal of Virology
2011-09 | Journal article | Author
DOI: 10.1128/JVI.02561-10
SOURCE-WORK-ID:

ee9dc747-416a-4011-9023-82806874adde

EID:

2-s2.0-80052293913

PMID: 21697493
Contributors: Jiping Yue; Ruchi Shukla; Rosita Accardi; Isabelle Zanella-Cleon; Maha Siouda; Marie Pierre Cros; Vladimir Krutovskikh; Ishraq Hussain; Yamei Niu; Shiqiong Hu et al.
Source: check_circle
Northumbria University

NF-κB protects human papillomavirus type 38 E6/E7-immortalized human keratinocytes against tumor necrosis factor alpha and UV-mediated apoptosis

Journal of Virology
2011-09 | Journal article | Author
DOI: 10.1128/JVI.00002-11
SOURCE-WORK-ID:

1df63b31-254a-49a1-97c7-5506290ddf9e

EID:

2-s2.0-80052286626

PMID: 21715489
Contributors: Ishraq Hussain; Ikbal Fathallah; Rosita Accardi; Jiping Yue; Djamel Saidj; Ruchi Shukla; Uzma Hasan; Tarik Gheit; Yamei Niu; Massimo Tommasino et al.
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Northumbria University

Proinflammatory cytokine TNF-α increases the stability of hepatitis B virus X protein through NF-κB signaling

Carcinogenesis
2011-07-01 | Journal article | Author
DOI: 10.1093/carcin/bgr057
SOURCE-WORK-ID:

b09c1098-776d-4c21-9d54-863e298bd1fa

EID:

2-s2.0-79960040702

PMID: 21459755
Contributors: Ruchi Shukla; Jiping Yue; Maha Siouda; Tarik Gheit; Olivier Hantz; Philippe Merle; Fabien Zoulim; Vladimir Krutovskikh; Massimo Tommasino; Bakary S. Sylla
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Northumbria University

Adipogenic action of vanadium

BioMetals
2008-04 | Journal article | Author
DOI: 10.1007/s10534-007-9109-4
SOURCE-WORK-ID:

b222cba1-0f40-4f0b-a21b-76227c2b747e

EID:

2-s2.0-41049083130

PMID: 17671828
Contributors: Ruchi Shukla; Ramesh R. Bhonde
Source: check_circle
Northumbria University

Mouse recombinant leptin protects human hepatoma HepG2 against apoptosis, TNF-α response and oxidative stress induced by the hepatotoxin-ethanol

Biochimica et Biophysica Acta - General Subjects
2007-08 | Journal article | Author
DOI: 10.1016/j.bbagen.2007.04.009
SOURCE-WORK-ID:

6632b000-d55a-4726-8409-0691543e8c76

EID:

2-s2.0-34347252655

PMID: 17543459
Contributors: Vairappan Balasubramaniyan; Ruchi Shukla; Gopal Murugaiyan; Ramchandra Ramesh Bhonde; Namasivayam Nalini
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Northumbria University

Bis(quercetinato)oxovanadium IV reverses metabolic changes in streptozotocin-induced diabetic mice

Review of Diabetic Studies
2007-03 | Journal article | Author
DOI: 10.1900/RDS.2007.4.33
SOURCE-WORK-ID:

2f1dd62c-31c0-4b81-8426-7ca1a6645c9f

EID:

2-s2.0-34548821581
Contributors: Ruchi Shukla; Subhash Padhye; Manisha Modak; Saroj S. Ghaskadbi; Ramesh R. Bhonde
Source: check_circle
Northumbria University

Leptin downregulates ethanol-induced secretion of proinflammatory cytokines and growth factor

Cytokine
2007-01 | Journal article | Author
DOI: 10.1016/j.cyto.2007.02.017
SOURCE-WORK-ID:

a0e4b3c3-ed8d-4bed-ab4b-31f691f4dfea

EID:

2-s2.0-34147136667

PMID: 17391979
Contributors: Vairappan Balasubramaniyan; Gopal Murugaiyan; Ruchi Shukla; Ramachandra Ramesh Bhonde; Namasivayam Nalini
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Northumbria University

Reduction of oxidative stress induced vanadium toxicity by complexing with a flavonoid, quercetin

BioMetals
2006-12 | Journal article | Author
DOI: 10.1007/s10534-006-9005-3
SOURCE-WORK-ID:

fa4604fb-21b6-4b93-978b-f50eb087aad4

EID:

2-s2.0-33750616036

PMID: 16703281
Contributors: Ruchi Shukla; Vivek Barve; Subhash Padhye; Ramesh Bhonde
Source: check_circle
Northumbria University

Synthesis, structural properties and insulin-enhancing potential of bis(quercetinato)oxovanadium(IV) conjugate

Bioorganic and Medicinal Chemistry Letters
2004-10-04 | Journal article | Author
DOI: 10.1016/j.bmcl.2004.07.020
SOURCE-WORK-ID:

280e9191-b10d-4322-935a-88c8e24e85a0

EID:

2-s2.0-4444258815

PMID: 15341960
Contributors: Ruchi Shukla; Vivek Barve; Subhash Padhye; Ramesh Bhonde
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Northumbria University

Peer review (7 reviews for 4 publications/grants)

Review activity for Cellular & Molecular Biology Letters. (1)
Review activity for JHEP reports. (2)
Review activity for Journal of experimental & clinical cancer research. (2)
Review activity for Nature structural & molecular biology. (2)
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