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Scopus Author ID: 57878437300
SciProfiles: 2356831

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Works (12)

Development of selective sigma-1 receptor ligands with antiallodynic activity: A focus on piperidine and piperazine scaffolds

European Journal of Medicinal Chemistry
2025 | Journal article
DOI: 10.1016/j.ejmech.2024.117037
EID:

2-s2.0-85208762120

Part of ISSN: 17683254 02235234
Contributors: Cosentino, G.; Dichiara, M.; Ambrosio, F.A.; Leotta, C.G.; Costa, G.; Procopio, F.; Costanzo, G.; Raffa, A.; Artacho-Cordón, A.; Ruiz-Cantero, M.C. et al.
Source: Self-asserted source
Costanzo Giuliana via Scopus - Elsevier

Novel sigma 1-antagonists with cis-(+)-normetazocine scaffold: synthesis, molecular modeling, and antinociceptive effect

RSC Medicinal Chemistry
2025 | Journal article
DOI: 10.1039/D4MD00397G
Contributors: Giuliana Costanzo; Giuseppe Cosentino; Margherita Grasso; Vincenzo Patamia; Sara Zuccalà; Alessandro Coco; Elisabetta Novello; Mahmoud Al-Khrasani; Raffaele Morrone; Giovanni Mario Pitari et al.
Source: check_circle
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Designing drugs optimized for both blood–brain barrier permeation and intra-cerebral partition

Expert Opinion on Drug Discovery
2024 | Journal article
DOI: 10.1080/17460441.2023.2294118
EID:

2-s2.0-85180482119

Part of ISSN: 1746045X 17460441
Contributors: Dichiara, M.; Cosentino, G.; Giordano, G.; Pasquinucci, L.; Marrazzo, A.; Costanzo, G.; Amata, E.
Source: Self-asserted source
Costanzo Giuliana via Scopus - Elsevier

From Plant to Chemistry: Sources of Antinociceptive Non-Opioid Active Principles for Medicinal Chemistry and Drug Design

Molecules
2024 | Journal article
DOI: 10.3390/molecules29040815
EID:

2-s2.0-85186265653

Part of ISSN: 14203049
Contributors: Turnaturi, R.; Piana, S.; Spoto, S.; Costanzo, G.; Reina, L.; Pasquinucci, L.; Parenti, C.
Source: Self-asserted source
Costanzo Giuliana via Scopus - Elsevier
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Sigma-1 Receptor Inhibition Reduces Mechanical Allodynia and Modulate Neuroinflammation in Chronic Neuropathic Pain

Molecular Neurobiology
2024 | Journal article
DOI: 10.1007/s12035-023-03717-w
EID:

2-s2.0-85175625246

Part of ISSN: 15591182 08937648
Contributors: Denaro, S.; Pasquinucci, L.; Turnaturi, R.; Alberghina, C.; Longhitano, L.; Giallongo, S.; Costanzo, G.; Spoto, S.; Grasso, M.; Zappalà, A. et al.
Source: Self-asserted source
Costanzo Giuliana via Scopus - Elsevier

Two-Step Synthesis of Enantiomerically Pure Morphans from (R)-Carvone

ChemMedChem
2024 | Journal article
DOI: 10.1002/cmdc.202400596
EID:

2-s2.0-85207562900

Part of ISSN: 18607187 18607179
Contributors: Costanzo, G.; Cosentino, G.; Pasquinucci, L.; Amata, E.; Schepmann, D.; Wünsch, B.
Source: Self-asserted source
Costanzo Giuliana via Scopus - Elsevier

Design, Synthesis, and Evaluation of Novel (−)‐cis‐N‐Normetazocine Derivatives: In Vitro and Molecular Modeling Insights

Chemical Biology & Drug Design
2024-12 | Journal article
DOI: 10.1111/cbdd.70037
Contributors: Giuliana Costanzo; Alessandro Coco; Giuseppe Cosentino; Vincenzo Patamia; Carmela Parenti; Emanuele Amata; Agostino Marrazzo; Antonio Rescifina; Lorella Pasquinucci
Source: check_circle
Crossref

Design, synthesis, in vitro evaluation, and molecular modeling studies of N-substituted benzomorphans, analogs of LP2, as novel MOR ligands

Chemical Biology and Drug Design
2023 | Journal article
DOI: 10.1111/cbdd.14220
EID:

2-s2.0-85150289416

Part of ISSN: 17470285 17470277
Contributors: Costanzo, G.; Patamia, V.; Turnaturi, R.; Parenti, C.; Zagni, C.; Lombino, J.; Amata, E.; Marrazzo, A.; Pasquinucci, L.; Rescifina, A.
Source: Self-asserted source
Costanzo Giuliana via Scopus - Elsevier

Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity

Journal of Medicinal Chemistry
2023 | Journal article
DOI: 10.1021/acs.jmedchem.3c00959
EID:

2-s2.0-85168325923

Part of ISSN: 15204804 00222623
Contributors: Dichiara, M.; Ambrosio, F.A.; Lee, S.M.; Ruiz-Cantero, M.C.; Lombino, J.; Coricello, A.; Costa, G.; Shah, D.; Costanzo, G.; Pasquinucci, L. et al.
Source: Self-asserted source
Costanzo Giuliana via Scopus - Elsevier

From Plant to Chemistry: Sources of Active Opioid Antinociceptive Principles for Medicinal Chemistry and Drug Design

Molecules
2023 | Journal article
DOI: 10.3390/molecules28207089
EID:

2-s2.0-85175056003

Part of ISSN: 14203049
Contributors: Turnaturi, R.; Piana, S.; Spoto, S.; Costanzo, G.; Reina, L.; Pasquinucci, L.; Parenti, C.
Source: Self-asserted source
Costanzo Giuliana via Scopus - Elsevier
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New Insights into the Opioid Analgesic Profile of cis-(−)-N-Normetazocine-derived Ligands

Molecules
2023 | Journal article
DOI: 10.3390/molecules28124827
EID:

2-s2.0-85164005071

Part of ISSN: 14203049
Contributors: Costanzo, G.; Turnaturi, R.; Parenti, C.; Spoto, S.; Piana, S.; Dichiara, M.; Zagni, C.; Galambos, A.R.; Essmat, N.; Marrazzo, A. et al.
Source: Self-asserted source
Costanzo Giuliana via Scopus - Elsevier
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Novel N-normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics in Inflammatory Pain

Molecules
2022 | Journal article
DOI: 10.3390/molecules27165135
EID:

2-s2.0-85137483599

Part of ISSN: 14203049
Contributors: Turnaturi, R.; Chiechio, S.; Pasquinucci, L.; Spoto, S.; Costanzo, G.; Dichiara, M.; Piana, S.; Grasso, M.; Amata, E.; Marrazzo, A. et al.
Source: Self-asserted source
Costanzo Giuliana via Scopus - Elsevier
grade
Preferred source (of 3)‎
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