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Employment (1)

Enveda Biosciences: Salt Lake City, UT, US

2021-02-01 to present | VP Data Science (Data Science)
Employment
Source: Self-asserted source
David Healey

Education and qualifications (1)

Massachusetts Institute of Technology: Cambridge, Massachusetts, US

2010-09-01 to 2015-05-01 | Ph.D. (Biology)
Education
Source: Self-asserted source
David Healey

Works (24)

Evaluating the generalizability of graph neural networks for predicting collision cross section

Journal of Cheminformatics
2024 | Journal article
Contributors: Engler Hart, Chloe; Preto, António José; Chanana, Shaurya; Healey, David; Kind, Tobias; Domingo-Fernández, Daniel
Source: Self-asserted source
David Healey

Natural Products Have Increased Rates of Clinical Trial Success throughout the Drug Development Process

Journal of Natural Products
2024 | Journal article
Contributors: Domingo-Fernández, Daniel; Gadiya, Yojana; Preto, António José; Krettler, Christoph A; Mubeen, Sarah; Allen, August; Healey, David; Colluru, Viswa
Source: Self-asserted source
David Healey

Weighting Low-Intensity MS/MS Ions and m/z Frequency for Spectral Library Annotation

Journal of the American Society for Mass Spectrometry
2024 | Journal article
Contributors: Engler Hart, Chloe; Kind, Tobias; Dorrestein, Pieter C; Healey, David; Domingo-Fernández, Daniel
Source: Self-asserted source
David Healey

Systems and methods for high throughput compound library creation

2024-06 | Other
Contributors: Gibson, Chris; Borgeson, Blake C; Victors, Mason L; Healey, David; Quigley, Ian; Alfa, Ronald Wakim
Source: Self-asserted source
David Healey

Efficiently predicting high resolution mass spectra with graph neural networks

International Conference on Machine Learning
2023 | Conference paper
Contributors: Murphy, Michael; Jegelka, Stefanie; Fraenkel, Ernest; Kind, Tobias; Healey, David; Butler, Thomas
Source: Self-asserted source
David Healey

Exploring the known chemical space of the plant kingdom: insights into taxonomic patterns, knowledge gaps, and bioactive regions

Journal of Cheminformatics
2023 | Journal article
Contributors: Domingo-Fernández, Daniel; Gadiya, Yojana; Mubeen, Sarah; Healey, David; Norman, Bryan H; Colluru, Viswa
Source: Self-asserted source
David Healey

Human nuclear hormone receptor activity contributes to malaria parasite liver stage development

Cell chemical biology
2023 | Journal article
Contributors: Mittal, Nimisha; Davis, Chadwick; McLean, Peter; Calla, Jaeson; Godinez-Macias, Karla P; Gardner, Alison; Healey, David; Orjuela-Sanchez, Pamela; Ottilie, Sabine; Chong, Yolanda et al.
Source: Self-asserted source
David Healey

Modern drug discovery using ethnobotany: a large-scale cross-cultural analysis of traditional medicine reveals common therapeutic uses

Iscience
2023 | Journal article
Contributors: Domingo-Fernández, Daniel; Gadiya, Yojana; Mubeen, Sarah; Bollerman, Thomas Joseph; Healy, Matthew D; Chanana, Shaurya; Sadovsky, Rotem Gura; Healey, David; Colluru, Viswa
Source: Self-asserted source
David Healey

MS2Mol: A transformer model for illuminating dark chemical space from mass spectra

2023 | Journal article
Contributors: Butler, Thomas; Frandsen, Abraham; Lightheart, Rose; Bargh, Brian; Taylor, James; Bollerman, TJ; Kerby, Thomas; West, Kiana; Voronov, Gennady; Moon, Kevin et al.
Source: Self-asserted source
David Healey

On the correspondence between the transcriptomic response of a compound and its effects on its targets

BMC bioinformatics
2023 | Journal article
Contributors: Engler Hart, Chloe; Ence, Daniel; Healey, David; Domingo-Fernández, Daniel
Source: Self-asserted source
David Healey

Causal reasoning over knowledge graphs leveraging drug-perturbed and disease-specific transcriptomic signatures for drug discovery

PLoS computational biology
2022 | Journal article
Contributors: Domingo-Fernández, Daniel; Gadiya, Yojana; Patel, Abhishek; Mubeen, Sarah; Rivas-Barragan, Daniel; Diana, Chris W; Misra, Biswapriya B; Healey, David; Rokicki, Joe; Colluru, Viswa
Source: Self-asserted source
David Healey

Ensembles of knowledge graph embedding models improve predictions for drug discovery

Briefings in Bioinformatics
2022 | Journal article
Contributors: Rivas-Barragan, Daniel; Domingo-Fernández, Daniel; Gadiya, Yojana; Healey, David
Source: Self-asserted source
David Healey

MS2Prop: A machine learning model that directly generates de novo predictions of drug-likeness of natural products from unannotated MS/MS spectra

bioRxiv
2022 | Journal article
Contributors: Voronov, Gennady; Lightheart, Rose; Frandsen, Abe; Bargh, Brian; Haynes, Sarah E; Spencer, Elizabeth; Schoenhardt, Katherine E; Davidson, Christina; Schaum, Andre; Macherla, Venkat R et al.
Source: Self-asserted source
David Healey

Multi-scale sinusoidal embeddings enable learning on high resolution mass spectrometry data

arXiv preprint arXiv:2207.02980
2022 | Journal article
Contributors: Voronov, Gennady; Lightheart, Rose; Davison, Joe; Krettler, Christoph A; Healey, David; Butler, Thomas
Source: Self-asserted source
David Healey

Ensembles of knowledge graph embedding models improve predictions for drug discovery

Briefings in Bioinformatics
2022-11-19 | Journal article
Contributors: Daniel Rivas-Barragan; Daniel Domingo-Fernández; Yojana Gadiya; David Healey
Source: check_circle
Crossref

Systems and methods for high throughput compound library creation

2022-07 | Other
Contributors: Gibson, Chris; Borgeson, Blake C; Victors, Mason L; Healey, David; Quigley, Ian; Alfa, Ronald Wakim
Source: Self-asserted source
David Healey

Causal reasoning over knowledge graphs leveraging drug-perturbed and disease-specific transcriptomic signatures for drug discovery

PLOS Computational Biology
2022-02-25 | Journal article
Contributors: Daniel Domingo-Fernández; Carl Herrmann; Yojana Gadiya; Abhishek Patel; Sarah Mubeen; Daniel Rivas-Barragan; Chris W. Diana; Biswapriya B. Misra; David Healey; Joe Rokicki et al.
Source: check_circle
Crossref

Negative frequency-dependent interactions can underlie phenotypic heterogeneity in a clonal microbial population

Molecular systems biology
2016 | Journal article
Contributors: Healey, David; Axelrod, Kevin; Gore, Jeff
Source: Self-asserted source
David Healey

Nascent peptides that block protein synthesis in bacteria

Proceedings of the National Academy of Sciences
2013 | Journal article
Contributors: Woolstenhulme, Christopher J; Parajuli, Shankar; Healey, David W; Valverde, Diana P; Petersen, E Nicholas; Starosta, Agata L; Guydosh, Nicholas R; Johnson, W Evan; Wilson, Daniel N; Buskirk, Allen R
Source: Self-asserted source
David Healey

The mechanism by which tmRNA rescues stalled ribosomes

Ribosomes: Structure, Function, and Dynamics
2011 | Book chapter
Contributors: Healey, David; Miller, Mickey; Woolstenhulme, Christopher; Buskirk, Allen
Source: Self-asserted source
David Healey

Rapid behavior-based identification of neuroactive small molecules in the zebrafish

Nature chemical biology
2010 | Journal article
Contributors: Kokel, David; Bryan, Jennifer; Laggner, Christian; White, Rick; Cheung, Chung Yan J; Mateus, Rita; Healey, David; Kim, Sonia; Werdich, Andreas A; Haggarty, Stephen J et al.
Source: Self-asserted source
David Healey

SmpB Contributes to Reading Frame Selection in the Translation of Transfer--Messenger RNA

Journal of molecular biology
2009 | Journal article
Contributors: Watts, Talina; Cazier, DeAnna; Healey, David; Buskirk, Allen
Source: Self-asserted source
David Healey

The role of tmRNA nucleotides and the SmpB protein in setting the translational frame on tmRNA

2008 | Other
Contributors: Watts, Talina; Healey, David; Jones, DeAnna; Buskirk, Allen
Source: Self-asserted source
David Healey

The role of upstream sequences in selecting the reading frame on tmRNA

BMC biology
2008 | Journal article
Contributors: Miller, Mickey R; Healey, David W; Robison, Stephen G; Dewey, Jonathan D; Buskirk, Allen R
Source: Self-asserted source
David Healey