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carbohydrate, glycoconjugate, vaccine

Biography

PhD in Synthetic Organic Chemistry (Univ Paris-Orsay, 1994)
Research at the chemistry/biology (immunology) interfaces Studies of carbohydrate /protein interactions; design and preparation of glycoconjugate vaccines

Activities

Works (30)

Multivalent inhibition of the Aspergillus fumigatus KDNase

Organic & Biomolecular Chemistry
2024 | Journal article
Contributors: Mathieu Scalabrini; Denis Loquet; Camille Rochard; Mélyne Baudin Marie; Coralie Assailly; Yoan Brissonnet; Franck Daligault; Amélie Saumonneau; Annie Lambert; Cyrille Grandjean et al.
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Impedimetric Characterization of NanA Structural Domains Activity on Sialoside-Containing Interfaces

Langmuir
2024-10-22 | Journal article
Contributors: Israel Alshanski; Suraj Toraskar; Karin Mor; Franck Daligault; Prashant Jain; Cyrille Grandjean; Raghavendra Kikkeri; Mattan Hurevich; Shlomo Yitzchaik
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Crossref

Multivalent Inhibition of the Aspergillus fumigatus KDNase

2024-04-15 | Preprint
Contributors: Mathieu Scalabrini; Denis Loquet; Camille Rochard; Mélyne Baudin-Marie; Coralie Assailly; Yoan Brissonnet; Franck Daligault; Amélie Saumonneau; Annie Lambert; cyrille grandjean et al.
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Multivalent Inhibition of the Aspergillus fumigatus KDNase

2024-04-12 | Preprint
Contributors: Mathieu Scalabrini; Denis Loquet; Camille Rochard; Coralie Assailly; Yoan Brissonnet; Franck Daligault; Amélie Saumonneau; Annie Lambert; cyrille grandjean; david Deniaud et al.
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Crossref

Isolation and characterisation of an environmental Clostridium beijerinckii strain for biohydrogen production from dairy wastes

International Journal of Hydrogen Energy
2024-01 | Journal article
Contributors: M. Mete; P. Pattyn; A. Robidart; G. Beringuier; H. Thomas; C. Grandjean; R. Irague; Y. Andres
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Crossref

Semisynthetic Pneumococcal Glycoconjugate Nanovaccine

Bioconjugate Chemistry
2023-09-20 | Journal article
Contributors: Maruthi Prasanna; Rubén Varela Calvino; Annie Lambert; Maria Arista Romero; Sylvia Pujals; François Trottein; Emilie Camberlein; Cyrille Grandjean; Noemi Csaba
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Click-electrochemistry for the rapid labeling of virus, bacteria and cell surfaces

Nature Communications
2023-08-23 | Journal article
Contributors: Sébastien Depienne; Mohammed Bouzelha; Emmanuelle Courtois; Karine Pavageau; Pierre-Alban Lalys; Maia Marchand; Dimitri Alvarez-Dorta; Steven Nedellec; Laura Marín-Fernández; Cyrille Grandjean et al.
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Crossref

On the use of adenovirus dodecahedron as a carrier for glycoconjugate vaccines

Glycoconjugate Journal
2021-08-14 | Journal article
Contributors: Maruthi Prasanna; Malgorzata Podsiadla-Bialoskorska; Damian Mielecki; Nicolas Ruffier; Amina Fateh; Annie Lambert; Mathieu Fanuel; Emilie Camberlein; Ewa Szolajska; Cyrille Grandjean
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Crossref

Linear triazole‐linked pseudo oligogalactosides as scaffolds for galectin inhibitor development

Chemical Biology & Drug Design
2020-10 | Journal article
Contributors: Christophe Dussouy; Chandan Kishor; Annie Lambert; Clément Lamoureux; Helen Blanchard; Cyrille Grandjean
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Crossref

Binding of Gold(III) Porphyrin by the Pro-metastatic Regulatory Protein Human Galectin-3

Molecules
2019-12-12 | Journal article
Contributors: Vanya Bogoeva; Miroslav Rangelov; Nadezhda Todorova; Annie Lambert; Clarisse Bridot; Anna Yordanova; Goedele Roos; Cyrille Grandjean; Julie Bouckaert
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Crossref
grade
Preferred source (of 2)‎

Semisynthetic glycoconjugate based on dual role protein/PsaA as a pneumococcal vaccine

European Journal of Pharmaceutical Sciences
2019-03 | Journal article
Contributors: Maruthi Prasanna; Daphnée Soulard; Emilie Camberlein; Nicolas Ruffier; Annie Lambert; François Trottein; Noemi Csaba; Cyrille Grandjean
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Crossref

Biophysical and structural characterization of mono/di-arylated lactosamine derivatives interaction with human galectin-3

Biochemical and Biophysical Research Communications
2017-07 | Journal article
Contributors: Cédric Atmanene; Céline Ronin; Stéphane Téletchéa; François-Moana Gautier; Florence Djedaïni-Pilard; Fabrice Ciesielski; Valérie Vivat; Cyrille Grandjean
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Crossref

Back Cover: Lactosamine‐Based Derivatives as Tools to Delineate the Biological Functions of Galectins: Application to Skin Tissue Repair (ChemBioChem 8/2017)

ChemBioChem
2017-04-18 | Journal article
Contributors: Johann Dion; Frédérique Deshayes; Nataliya Storozhylova; Tamara Advedissian; Annie Lambert; Mireille Viguier; Charles Tellier; Christophe Dussouy; Françoise Poirier; Cyrille Grandjean
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Crossref

Lactosamine‐Based Derivatives as Tools to Delineate the Biological Functions of Galectins: Application to Skin Tissue Repair

ChemBioChem
2017-04-18 | Journal article
Contributors: Johann Dion; Frédérique Deshayes; Nataliya Storozhylova; Tamara Advedissian; Annie Lambert; Mireille Viguier; Charles Tellier; Christophe Dussouy; Françoise Poirier; Cyrille Grandjean
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Crossref

A one dose experimental cholera vaccine

Journal article
DOI:

10.1111/j.1574-695X.2012.00993.x

Source: Self-asserted source
Cyrille Grandjean

Access to Antigens Related to Anthrose Using Pivotal Cyclic Sulfite/Sulfate Intermediates

Journal article
DOI:

10.1021/jo200340q

Source: Self-asserted source
Cyrille Grandjean

Carbopalladation of functionalized allenes: regioselectivity of the reaction of carbonucleophiles with the intermediate -allyl palladium complexes

Journal article | Assignee
Contributors: Cyrille Grandjean
Source: Self-asserted source
Cyrille Grandjean

ChemInform Abstract: Synthesis and Biological Activity of Natural Aminocyclopentitol Glycosidase Inhibitors: Mannostatins, Trehazolin, Allosamidins, and Their Analogues

Journal article
DOI:

10.1002/chin.199921281

Source: Self-asserted source
Cyrille Grandjean

Combined Thioether/Hydrazone Chemoselective Ligation Reactions for the Synthesis of Glycocluster−Antigen Peptide Conjugates

Journal article
DOI:

10.1021/bc025505o

Source: Self-asserted source
Cyrille Grandjean

Convergent synthesis of fluorescein-labelled lysine-based cluster glycosides

Journal article
DOI:

10.1016/S0040-4039(99)01535-X

Source: Self-asserted source
Cyrille Grandjean

Cover Picture

Journal article
DOI:

10.1002/1439-7633(20011001)2:10<717::AID-CBIC717>3.0.CO;2-#

Source: Self-asserted source
Cyrille Grandjean

Efficient preparation of carbohydrate- and related polyol-amphiphiles by hydrazone ligation

Journal article
DOI:

10.1016/j.tetlet.2004.03.011

Source: Self-asserted source
Cyrille Grandjean

Investigation towards bivalent chemically defined glycoconjugate immunogens prepared from acid-detoxified lipopolysaccharide of Vibrio cholerae O1, serotype Inaba

Journal article
DOI:

10.1007/s10719-008-9160-6

Source: Self-asserted source
Cyrille Grandjean

Novel Hyperbranched Glycomimetics Recognized by the Human Mannose Receptor: Quinic or Shikimic Acid Derivatives as Mannose Bioisosteres

Journal article
DOI:

10.1002/1439-7633(20011001)2:10<747::AID-CBIC747>3.0.CO;2-O

Source: Self-asserted source
Cyrille Grandjean

One-Pot Synthesis of Antigen-Bearing, Lysine-Based Cluster Mannosides Using Two Orthogonal Chemoselective Ligation Reactions

Journal article
DOI:

10.1002/(SICI)1521-3773(20000317)39:6<1068::AID-ANIE1068>3.0.CO;2-4

Source: Self-asserted source
Cyrille Grandjean

SN2Displacement of Carbohydrate Triflates by 9-Oximes of Erythromycin A and Of a Tylosin Derivative

Journal article
DOI:

10.1080/07328309608005695

Source: Self-asserted source
Cyrille Grandjean

Synthesis and Biological Activity of Natural Aminocyclopentitol Glycosidase Inhibitors:  Mannostatins, Trehazolin, Allosamidins, and Their Analogues

Journal article
DOI:

10.1021/cr980033l

Source: Self-asserted source
Cyrille Grandjean

Synthesis of Clustered Glycoside-Antigen Conjugates by Two One-Pot, Orthogonal, Chemoselective Ligation Reactions: Scope and Limitations

Journal article
DOI:

10.1002/1521-3765(20010105)7:1<230::AID-CHEM230>3.0.CO;2-L

Source: Self-asserted source
Cyrille Grandjean

Synthesis of Clustered Glycoside–Antigen Conjugates by Two One-Pot, Orthogonal, Chemoselective Ligation Reactions: Scope and Limitations

Journal article
DOI:

10.1002/1521-3765(20010105)7:1<230::AID-CHEM230>3.3.CO;2-C

Source: Self-asserted source
Cyrille Grandjean

The iodosulfonamidation of peracetylated glycals revisited: access to 1,2-di-nitrogenated sugars

Journal article
DOI:

10.1016/j.carres.2011.01.022

Source: Self-asserted source
Cyrille Grandjean

Peer review (9 reviews for 8 publications/grants)

Review activity for ACS infectious diseases. (1)
Review activity for ACS medicinal chemistry letters. (1)
Review activity for ChemBioChem. (1)
Review activity for ChemMedChem. (1)
Review activity for ChemPlusChem. (1)
Review activity for European journal of pharmacology. (1)
Review activity for Glycoconjugate journal. (1)
Review activity for Journal of medicinal chemistry. (2)