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Scopus Author ID: 55490434900

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Universiteit Utrecht: Utrecht, NL

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Utrecht University

Utrecht University: Utrecht, Utrecht, NL

2020-02-01 to present | Assistant professor (Chemistry)
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MP Baggelaar

Works (35)

Site-Specific Competitive Kinase Inhibitor Target Profiling Using Phosphonate Affinity Tags

Molecular & Cellular Proteomics
2025-02 | Journal article
DOI: 10.1016/j.mcpro.2025.100906
Contributors: Wouter van Bergen; Anneroos E. Nederstigt; Albert J.R. Heck; Marc P. Baggelaar
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Crossref
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A palmitoyl transferase chemical-genetic system to map ZDHHC-specific S-acylation

Nature Biotechnology
2024-10 | Journal article | Author
DOI: 10.1038/s41587-023-02030-0
SOURCE-WORK-ID:

3fa64068-375e-4eec-810c-05c2f9a8ff3b

PMID: 38191663
EID:

2-s2.0-85181695602
Contributors: Cory A Ocasio; MP Baggelaar; James Sipthorp; Ana Losada de la Lastra; Manuel Tavares; Jana Volarić; Christelle Soudy; Elisabeth M Storck; Jack W Houghton; Susana A Palma-Duran et al.
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Utrecht University
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Dual-Probe Activity-Based Protein Profiling Reveals Site-Specific Differences in Protein Binding of EGFR-Directed Drugs

ACS Chemical Biology
2024-08-16 | Journal article
DOI: 10.1021/acschembio.3c00637
Contributors: Wouter van Bergen; Kristina Žuna; Jan Fiala; Elena E. Pohl; Albert J.R. Heck; Marc P. Baggelaar
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Crossref
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Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis

Cell Reports
2024-05-28 | Journal article | Author
DOI: 10.1016/j.celrep.2024.114224
SOURCE-WORK-ID:

5b5fde43-711c-4222-b66b-b78a8339200f

PMID: 38733589
EID:

2-s2.0-85192773456
Contributors: Goran Tomić; Clare Sheridan; Alice Y Refermat; MP Baggelaar; James Sipthorp; Bhuvana Sudarshan; Cory A Ocasio; Alejandro Suárez-Bonnet; Simon L Priestnall; Eleanor Herbert et al.
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Utrecht University

Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders

Brain
2024-04 | Journal article | Author
DOI: 10.1093/brain/awad380
SOURCE-WORK-ID:

b012e576-b3fe-4bee-87fb-66580295423c

PMID: 37951597
EID:

2-s2.0-85190176151
Contributors: Rauan Kaiyrzhanov; Aboulfazl Rad; Sheng-Jia Lin; Aida Bertoli-Avella; Wouter W Kallemeijn; Annie Godwin; Maha S Zaki; Kevin Huang; Tracy Lau; Cassidy Petree et al.
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Utrecht University

Dual-Probe Activity-Based Protein Profiling Reveals Site-Specific Differences in Protein Binding of EGFR-Directed Drugs

2023-10-19 | Working paper | Author
DOI: 10.1101/2023.10.19.562725
SOURCE-WORK-ID:

d7bace55-c033-4b0c-9864-4e16fa37c28d
Contributors: Wouter van Bergen; Jan Fiala; Albert Heck; MP Baggelaar
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Utrecht University
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S‑Palmitoylation during Retinoic Acid-Induced Neuronal Differentiation of SH-SY5Y Neuroblastoma Cells

Journal of Proteome Research
2023-07-07 | Journal article | Author
DOI: 10.1021/acs.jproteome.3c00151
SOURCE-WORK-ID:

cc0e60ca-b18f-4e2f-bc21-46005fbb254c

EID:

2-s2.0-85164249976
Contributors: Samiksha Sardana; Anneroos E Nederstigt; MP Baggelaar
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Utrecht University
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A palmitoyl transferase chemical genetic system to map ZDHHC-specific S-acylation

bioRxiv
2023-04-18 | Working paper | Author
DOI: 10.1101/2023.04.18.537386v1
SOURCE-WORK-ID:

c66d2873-d9ff-40bf-a277-20e78d6b8b48
Contributors: Cory A. Ocasio; MP Baggelaar; James Sipthorp; Ana Losada de la Lastra; Jana Volarić; Christelle Soudy; Elisabeth M. Storck; Susana A. Palma-Duran; James I. MacRae; Goran Tomic et al.
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Utrecht University

Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis

bioRxiv
2023-02-08 | Working paper | Author
DOI: 10.1101/2023.02.08.527637v2
SOURCE-WORK-ID:

65e34cd5-6439-4fd5-8af2-e7bbc3b5e887
Contributors: Goran Tomic; Alice Y. Refermat; Clare Sheridan; MP Baggelaar; James Sipthorp; Bhuvana Sudarshan; Cory A. Ocasio; Alejandro Suárez-Bonnet; Simon L. Priestnall ; Eleanor Herbert et al.
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Utrecht University

Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis

2023-02-08 | Preprint
DOI: 10.1101/2023.02.08.527637
Contributors: Goran Tomić; Clare Sheridan; Alice Y. Refermat; Marc P. Baggelaar; James Sipthorp; Bhuvana Sudarshan; Cory A. Ocasio; Alejandro Suárez-Bonnet; Simon L. Priestnall; Eleanor Herbert et al.
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Crossref

Site-specific Activity-based Protein Profiling Using Phosphonate Handles

Molecular and Cellular Proteomics
2023-01-01 | Journal article | Author
DOI: 10.1016/j.mcpro.2022.100455
SOURCE-WORK-ID:

c588482d-3a01-4de8-84bb-400e24d2b38d

PMID: 36435334
EID:

2-s2.0-85145307168

WOSUID:

001003130000001
Contributors: Wouter van Bergen; Johannes F Hevler; Wei Wu; MP Baggelaar; Albert Heck
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Utrecht University
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Recent advancements in mass spectrometry-based tools to investigate newly synthesized proteins

Current Opinion in Chemical Biology
2022-02 | Journal article | Author
DOI: 10.1016/j.cbpa.2021.07.001
SOURCE-WORK-ID:

f79c6dab-e618-49a7-94e0-89bf70f54f1d

PMID: 34364788
EID:

2-s2.0-85111995296
Contributors: Wouter van Bergen; Albert Heck; MP Baggelaar
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Utrecht University
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ABHD2 Inhibitor Identified by Activity-Based Protein Profiling Reduces Acrosome Reaction

ACS Chemical Biology
2019-12-20 | Journal article | Author
DOI: 10.1021/acschembio.9b00824
SOURCE-WORK-ID:

2e9da2b8-b569-48ee-a038-783a9298c64c

PMID: 31697462
EID:

2-s2.0-85074952592
Contributors: MP Baggelaar; Hans den Dulk; Bogdan I Florea; Domenico Fazio; Davide Perruzza; Nicola Bernabò; Marcello Raspa; Antonius P A Janssen; Ferdinando Scavizzi; Barbara Barboni et al.
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Utrecht University
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ABHD2 Inhibitor Identified by Activity-Based Protein Profiling Reduces Acrosome Reaction

ACS Chemical Biology
2019-10 | Journal article
DOI: 10.1021/acschembio.9b00640
Contributors: Marc P. Baggelaar; Hans den Dulk; Bogdan I. Florea; Domenico Fazio; Nicola Bernabò; Marcello Raspa; Antonius P. A. Janssen; Ferdinando Scavizzi; Barbara Barboni; Hermen S. Overkleeft et al.
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Crossref

Activity-Based Protein Profiling Identifies α-Ketoamides as Inhibitors for Phospholipase A2 Group XVI

ACS Chemical Biology
2019-02-15 | Journal article | Author
DOI: 10.1021/acschembio.8b00969
SOURCE-WORK-ID:

3e5abe01-b739-429a-b969-b765c9e9297c

PMID: 30620559
EID:

2-s2.0-85060631643
Contributors: Juan Zhou; Elliot D Mock; Andrea Martella; Vasudev Kantae; Xinyu Di; Lindsey Burggraaff; MP Baggelaar; Karol Al-Ayed; Alexander Bakker; Bogdan I Florea et al.
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Utrecht University

2-Arachidonoylglycerol

Progress in Lipid Research
2018-07 | Journal article | Author
DOI: 10.1016/j.plipres.2018.05.002
SOURCE-WORK-ID:

f10331ec-6598-40f7-ba27-381110ffed53

PMID: 29751000
EID:

2-s2.0-85047214083
Contributors: MP Baggelaar; Mauro Maccarrone; Mario van der Stelt
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Utrecht University
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Chemical Proteomic Analysis of Serine Hydrolase Activity in Niemann-Pick Type C Mouse Brain

Frontiers in Neuroscience
2018-07 | Journal article | Author
DOI: 10.3389/fnins.2018.00440
SOURCE-WORK-ID:

a54aaa75-6b53-4261-8d25-a9ec8ede5ba6

PMID: 30018533
EID:

2-s2.0-85049992979
Contributors: Eva J van Rooden; Annelot C M van Esbroeck; MP Baggelaar; Hui Deng; Bogdan I Florea; André R A Marques; Roelof Ottenhoff; Rolf G Boot; Herman S Overkleeft; Johannes M F G Aerts et al.
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Utrecht University
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Mapping in vivo target interaction profiles of covalent inhibitors using chemical proteomics with label-free quantification

Nature protocols
2018-04 | Journal article | Author
DOI: 10.1038/nprot.2017.159
SOURCE-WORK-ID:

5273e472-3a96-4f28-873e-5600d81e91ba

PMID: 29565900
EID:

2-s2.0-85044270875
Contributors: Eva J van Rooden; Bogdan I Florea; Hui Deng; MP Baggelaar; Annelot C M van Esbroeck; Juan Zhou; Herman S Overkleeft; Mario van der Stelt
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Utrecht University
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Competitive ABPP of Serine Hydrolases

Methods in Molecular Biology
2017 | Journal article | Author
DOI: 10.1007/978-1-4939-6439-0_12
SOURCE-WORK-ID:

fc21c3f5-bea3-44c6-bd6f-1704b8fae563

PMID: 27778288
EID:

2-s2.0-84992530822
Contributors: MP Baggelaar; Mario Van der Stelt
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Utrecht University
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Novel activity-based probes for N-acylethanolamine acid amidase

Chemical communications (Cambridge, England)
2017-08-22 | Journal article | Author
DOI: 10.1039/c7cc06838g
SOURCE-WORK-ID:

a27a0901-3b00-4acd-a4fa-ebb796e9d5f8

PMID: 29035406
EID:

2-s2.0-85032455903
Contributors: Rita Petracca; Elisa Romeo; MP Baggelaar; Marta Artola; Silvia Pontis; Stefano Ponzano; Herman S Overkleeft; Mario van der Stelt; Daniele Piomelli
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Utrecht University
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Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474

Science (New York, N.Y.)
2017-06-09 | Journal article | Author
DOI: 10.1126/science.aaf7497
SOURCE-WORK-ID:

99f5abf8-787f-458e-83a0-d9d00d1fcbc5

PMID: 28596366
EID:

2-s2.0-85020735085
Contributors: Annelot C M van Esbroeck; Antonius P A Janssen; Armand B Cognetta; Daisuke Ogasawara; Guy Shpak; Mark van der Kroeg; Vasudev Kantae; MP Baggelaar; Femke M S de Vrij; Hui Deng et al.
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Utrecht University
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Chiral disubstituted piperidinyl ureas

MedChemComm
2017-05-01 | Journal article | Author
DOI: 10.1039/c7md00029d
SOURCE-WORK-ID:

66da3d04-523d-4528-8dab-6f1b40215733

PMID: 30108813
EID:

2-s2.0-85022100143
Contributors: Hui Deng; Tom van der Wel; Richard J B H N van den Berg; Adrianus M C H van den Nieuwendijk; Freek J Janssen; MP Baggelaar; Hermen S Overkleeft; Mario van der Stelt
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Utrecht University
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Chemical Proteomics Maps Brain Region Specific Activity of Endocannabinoid Hydrolases

ACS Chemical Biology
2017-03-17 | Journal article | Author
DOI: 10.1021/acschembio.6b01052
SOURCE-WORK-ID:

7f276529-3b43-4811-8db7-94fc960440e5

PMID: 28106377
EID:

2-s2.0-85015726009
Contributors: MP Baggelaar; Annelot C M van Esbroeck; Eva J van Rooden; Bogdan I Florea; Herman S Overkleeft; Giovanni Marsicano; Francis Chaouloff; Mario van der Stelt
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Utrecht University
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Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding

Journal of Medicinal Chemistry
2017-01-12 | Journal article | Author
DOI: 10.1021/acs.jmedchem.6b01482
SOURCE-WORK-ID:

b72fc9bf-f507-42a8-93e6-b36b52e6942a

PMID: 27992221
EID:

2-s2.0-85018503392
Contributors: Hui Deng; Sander Kooijman; Adrianus M C H van den Nieuwendijk; Daisuke Ogasawara; Tom van der Wel; Floris van Dalen; MP Baggelaar; Freek J Janssen; Richard J B H N van den Berg; Hans den Dulk et al.
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Utrecht University
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Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity

Nature Communications
2017-01-03 | Journal article | Author
DOI: 10.1038/ncomms13958
SOURCE-WORK-ID:

3f0eee1c-5f2e-45c9-b67b-ba713127b9d5

PMID: 28045021
EID:

2-s2.0-85008415005
Contributors: Marjolein Soethoudt; Uwe Grether; Jürgen Fingerle; Travis W Grim; Filomena Fezza; Luciano de Petrocellis; Christoph Ullmer; Benno Rothenhäusler; Camille Perret; Noortje van Gils et al.
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Utrecht University
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The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity

British Journal of Pharmacology
2016-02 | Journal article | Author
DOI: 10.1111/bph.13338
SOURCE-WORK-ID:

552c6757-1462-4592-bbbd-2dc26c5eecbe

PMID: 26398481
EID:

2-s2.0-84956664895
Contributors: Partha Mukhopadhyay; MP Baggelaar; Katalin Erdelyi; Zongxian Cao; Resat Cinar; Filomena Fezza; Bogna Ignatowska-Janlowska; Jenny Wilkerson; Noortje van Gils; Thomas Hansen et al.
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Utrecht University
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Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition

Proceedings of the National Academy of Sciences of the United States of America
2016-01-05 | Journal article | Author
DOI: 10.1073/pnas.1522364112
SOURCE-WORK-ID:

a729c83c-a9f0-4061-bbe7-4876b707baec

PMID: 26668358
EID:

2-s2.0-84953225327
Contributors: Daisuke Ogasawara; Hui Deng; Andreu Viader; MP Baggelaar; Arjen Breman; Hans den Dulk; Adrianus M C H van den Nieuwendijk; Marjolein Soethoudt; Tom van der Wel; Juan Zhou et al.
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Utrecht University
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Comprehensive Analysis of Structure-Activity Relationships of α-Ketoheterocycles as sn-1-Diacylglycerol Lipase α Inhibitors

Journal of Medicinal Chemistry
2015-12-24 | Journal article | Author
DOI: 10.1021/acs.jmedchem.5b01627
SOURCE-WORK-ID:

3862fe97-009c-4cf9-8755-876b21145555

EID:

2-s2.0-84953215126

PMID: 26584396
Contributors: Freek J. Janssen; MP Baggelaar; Jessica J.A. Hummel; Herman S. Overkleeft; Benjamin F. Cravatt; Dale L. Boger; Mario Van Der Stelt
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Utrecht University
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Highly Selective, Reversible Inhibitor Identified by Comparative Chemoproteomics Modulates Diacylglycerol Lipase Activity in Neurons

Journal of the American Chemical Society
2015-07-15 | Journal article | Author
DOI: 10.1021/jacs.5b04883
SOURCE-WORK-ID:

57d89eaf-3ce0-45c9-8900-f7f7d58c2bed

EID:

2-s2.0-84937133298

PMID: 26083464
Contributors: MP Baggelaar; Pascal J.P. Chameau; Vasudev Kantae; Jessica Hummel; Ku Lung Hsu; Freek Janssen; Tom Van Der Wel; Marjolein Soethoudt; Hui Deng; Hans Den Dulk et al.
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Utrecht University
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A natural substrate-based fluorescence assay for inhibitor screening on diacylglycerol lipase α

Journal of Lipid Research
2015-04 | Journal article | Author
DOI: 10.1194/jlr.D056390
SOURCE-WORK-ID:

1a7b73ce-36ff-4344-a12b-b4f966ee868a

PMID: 25684760
EID:

2-s2.0-84927534632
Contributors: Tom van der Wel; Freek J Janssen; MP Baggelaar; Hui Deng; Hans den Dulk; Herman S Overkleeft; Mario van der Stelt
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Utrecht University
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Development of an acid ceramidase activity-based probe

Chemical communications (Cambridge, England)
2015-04-11 | Journal article | Author
DOI: 10.1039/c5cc00356c
SOURCE-WORK-ID:

49575389-4a0e-4129-8b76-fcdaf4a245b5

PMID: 25748248
EID:

2-s2.0-84925673044
Contributors: Cécile M J Ouairy; Maria J Ferraz; Rolf G Boot; MP Baggelaar; Mario van der Stelt; Monique Appelman; Gijsbert A van der Marel; Bogdan I Florea; Johannes M F G Aerts; Herman S Overkleeft
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Utrecht University
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Discovery of glycine sulfonamides as dual inhibitors of sn-1-diacylglycerol lipase α and α/β-hydrolase domain 6

Journal of Medicinal Chemistry
2014-08-14 | Journal article | Author
DOI: 10.1021/jm500681z
SOURCE-WORK-ID:

59784795-b26d-4702-9224-2a5552cfb4bd

PMID: 24988361
EID:

2-s2.0-84906091270
Contributors: Freek J Janssen; Hui Deng; MP Baggelaar; Marco Allarà; Tom van der Wel; Hans den Dulk; Alessia Ligresti; Annelot C M van Esbroeck; Ross McGuire; Vincenzo Di Marzo et al.
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Utrecht University
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Development of an activity-based probe and in silico design reveal highly selective inhibitors for diacylglycerol lipase-α in brain

Angewandte Chemie-International Edition
2013-11-11 | Journal article | Author
DOI: 10.1002/anie.201306295
SOURCE-WORK-ID:

6366c843-9c7f-44c3-b887-0e84ca7fa61e

PMID: 24173880
EID:

2-s2.0-84887498917
Contributors: MP Baggelaar; Freek J Janssen; Annelot C M van Esbroeck; Hans den Dulk; Marco Allarà; Sascha Hoogendoorn; Ross McGuire; Bogdan I Florea; Nico Meeuwenoord; Hans van den Elst et al.
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Utrecht University
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Catalytic asymmetric total synthesis of (S)-(-)-zearalenone, a novel lipoxygenase inhibitor

Bioorganic & Medicinal Chemistry
2013-09-01 | Journal article | Author
DOI: 10.1016/j.bmc.2013.06.024
SOURCE-WORK-ID:

38094f7d-3a1a-40ca-94b1-d91a673fcc4a

PMID: 23867388
EID:

2-s2.0-84881377781
Contributors: MP Baggelaar; Yange Huang; Ben L Feringa; Frank J Dekker; Adriaan J Minnaard
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Utrecht University
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Total synthesis of the triglycosyl phenolic glycolipid PGL-tb1 from Mycobacterium tuberculosis

Angewandte Chemie-International Edition
2012-11-19 | Journal article | Author
DOI: 10.1002/anie.201206221
SOURCE-WORK-ID:

8afcb207-7623-42d1-b3d4-dd11a4186cb2

PMID: 23086739
EID:

2-s2.0-84869389626
Contributors: Santiago Barroso; Riccardo Castelli; MP Baggelaar; Danny Geerdink; Bjorn ter Horst; Eva Casas-Arce; Herman S Overkleeft; Gijsbert A van der Marel; Jeroen D C Codée; Adriaan J Minnaard
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Utrecht University
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Peer review (2 reviews for 2 publications/grants)

Review activity for Accounts of chemical research. (1)
Review activity for Current opinion in chemical biology. (1)
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