Personal information

Germany

Activities

Employment (4)

Anavo Therapeutics BV: Heidelberg, Baden-Württemberg, DE

2021-10-01 to present | SVP Biology
Employment
Source: Self-asserted source
Joe Lewis

EMBL Heidelberg Genomics Core Facility: Heidelberg, Baden-Württemberg, DE

2004-01-01 to 2021-07-31 | Head of Facility (Chemical Biology Core Facility)
Employment
Source: Self-asserted source
Joe Lewis

Elara Pharmaceuticals GmbH: Heidelberg, Baden-Württemberg, DE

2007-02-01 to 2013-03-31 | CEO
Employment
Source: Self-asserted source
Joe Lewis

Anadys Pharmaceuticals GmbH: Heidelberg, Baden-Wuerttemberg, DE

2001-06-01 to 2003-12-31 | Head of Target Discovery
Employment
Source: Self-asserted source
Joe Lewis

Education and qualifications (3)

Mannheim Business School: Mannheim, Baden-Württemberg, DE

2007-09-15 to 2008-06-08
Education
Source: Self-asserted source
Joe Lewis

Research Institute of Molecular Pathology: Vienna, AT

1987-10-01 to 1991-09-31 | Ph.D.
Education
Source: Self-asserted source
Joe Lewis

University of Edinburgh: Edinburgh, Edinburgh, GB

1983-10-15 to 1987-06-01 | B.Sc. (Hons) (Genetics)
Education
Source: Self-asserted source
Joe Lewis

Works (17)

Inferring tumor-specific cancer dependencies through integrating ex-vivo drug response assays and drug-protein profiling

2022-01-12 | Preprint
Contributors: Alina Batzilla; Junyan Lu; Jarno Kivioja; Kerstin Putzker; Joe Lewis; Thorsten Zenz; Wolfgang Huber
Source: check_circle
Crossref

The scaffold protein IQGAP1 links heat-induced stress signals to alternative splicing regulation in gastric cancer cells

Oncogene
2021-09-09 | Journal article
Contributors: Andrada-Maria Birladeanu; Malgorzata Rogalska; Myrto Potiri; Vasiliki Papadaki; Margarita Andreadou; Dimitris L. Kontoyiannis; Joe D. Lewis; Zoi Erpapazoglou; Panagiota Kafasla
Source: check_circle
Crossref

Loss of N-Glycanase 1 Alters Transcriptional and Translational Regulation in K562 Cell Lines.

G3 (Bethesda, Md.)
2020-05 | Journal article
Contributors: Mueller WF; Jakob P; Sun H; Clauder-Münster S; Ghidelli-Disse S; Ordonez D; Boesche M; Bantscheff M; Collier P; Haase B et al.
Source: Self-asserted source
Joe Lewis via Europe PubMed Central

A time-resolved live cell imaging assay to identify small molecule inhibitors of FGF2 signaling.

FEBS letters
2019-06 | Journal article
Contributors: Ahmed M; Legrand C; Yagüe Relimpio A; Beretta CA; Muschko A; Wegehingel S; Müller HM; Sehr P; Will DW; Lewis JD et al.
Source: Self-asserted source
Joe Lewis via Europe PubMed Central

Drug-perturbation-based stratification of blood cancer.

The Journal of clinical investigation
2017-12 | Journal article
Contributors: Dietrich S; Oleś M; Lu J; Sellner L; Anders S; Velten B; Wu B; Hüllein J; da Silva Liberio M; Walther T et al.
Source: Self-asserted source
Joe Lewis via Europe PubMed Central

Small-molecule inhibition of MuRF1 attenuates skeletal muscle atrophy and dysfunction in cardiac cachexia.

Journal of cachexia, sarcopenia and muscle
2017-09 | Journal article
Contributors: Bowen TS; Adams V; Werner S; Fischer T; Vinke P; Brogger MN; Mangner N; Linke A; Sehr P; Lewis J et al.
Source: Self-asserted source
Joe Lewis via Europe PubMed Central

Small Molecule Inhibitors Targeting Tec Kinase Block Unconventional Secretion of Fibroblast Growth Factor 2.

The Journal of biological chemistry
2016-07 | Journal article
Contributors: La Venuta G; Wegehingel S; Sehr P; Müller HM; Dimou E; Steringer JP; Grotwinkel M; Hentze N; Mayer MP; Will DW et al.
Source: Self-asserted source
Joe Lewis via Europe PubMed Central

Specific Inhibitors of HIV Capsid Assembly Binding to the C-Terminal Domain of the Capsid Protein: Evaluation of 2-Arylquinazolines as Potential Antiviral Compounds.

Journal of medicinal chemistry
2016-01 | Journal article
Contributors: Machara A; Lux V; Kožíšek M; Grantz Šašková K; Štěpánek O; Kotora M; Parkan K; Pávová M; Glass B; Sehr P et al.
Source: Self-asserted source
Joe Lewis via Europe PubMed Central

Improved synthesis of N-benzylaminoferrocene-based prodrugs and evaluation of their toxicity and antileukemic activity.

Journal of medicinal chemistry
2015-02 | Journal article
Contributors: Daum S; Chekhun VF; Todor IN; Lukianova NY; Shvets YV; Sellner L; Putzker K; Lewis J; Zenz T; de Graaf IA et al.
Source: Self-asserted source
Joe Lewis via Europe PubMed Central

5-azacytidine inhibits nonsense-mediated decay in a MYC-dependent fashion.

EMBO molecular medicine
2014-12 | Journal article
Contributors: Bhuvanagiri M; Lewis J; Putzker K; Becker JP; Leicht S; Krijgsveld J; Batra R; Turnwald B; Jovanovic B; Hauer C et al.
Source: Self-asserted source
Joe Lewis via Europe PubMed Central

A direct role for ATP1A1 in unconventional secretion of fibroblast growth factor 2.

The Journal of biological chemistry
2014-12 | Journal article
Contributors: Zacherl S; La Venuta G; Müller HM; Wegehingel S; Dimou E; Sehr P; Lewis JD; Erfle H; Pepperkok R; Nickel W
Source: Self-asserted source
Joe Lewis via Europe PubMed Central

New 7-methylguanine derivatives targeting the influenza polymerase PB2 cap-binding domain.

Journal of medicinal chemistry
2013-11 | Journal article
Contributors: Pautus S; Sehr P; Lewis J; Fortuné A; Wolkerstorfer A; Szolar O; Guilligay D; Lunardi T; Décout JL; Cusack S
Source: Self-asserted source
Joe Lewis via Europe PubMed Central

The novel toluidine sulphonamide EL102 shows pre-clinical in vitro and in vivo activity against prostate cancer and circumvents MDR1 resistance.

British journal of cancer
2013-09 | Journal article
Contributors: Toner AP; McLaughlin F; Giles FJ; Sullivan FJ; O'Connell E; Carleton LA; Breen L; Dunne G; Gorman AM; Lewis JD et al.
Source: Self-asserted source
Joe Lewis via Europe PubMed Central

Tripolin A, a novel small-molecule inhibitor of aurora A kinase, reveals new regulation of HURP's distribution on microtubules.

PloS one
2013-03 | Journal article
Contributors: Kesisova IA; Nakos KC; Tsolou A; Angelis D; Lewis J; Chatzaki A; Agianian B; Giannis A; Koffa MD
Source: Self-asserted source
Joe Lewis via Europe PubMed Central

ELR510444 inhibits tumor growth and angiogenesis by abrogating HIF activity and disrupting microtubules in renal cell carcinoma.

PloS one
2012-01 | Journal article
Contributors: Carew JS; Esquivel JA; Espitia CM; Schultes CM; Mülbaier M; Lewis JD; Janssen B; Giles FJ; Nawrocki ST
Source: Self-asserted source
Joe Lewis via Europe PubMed Central

High throughput screening against the peroxidase cascade of African trypanosomes identifies antiparasitic compounds that inactivate tryparedoxin.

The Journal of biological chemistry
2012-01 | Journal article
Contributors: Fueller F; Jehle B; Putzker K; Lewis JD; Krauth-Siegel RL
Source: Self-asserted source
Joe Lewis via Europe PubMed Central

Structure of the hepatitis C virus IRES bound to the human 80S ribosome: remodeling of the HCV IRES.

Structure (London, England : 1993)
2005-11 | Journal article
Contributors: Boehringer D; Thermann R; Ostareck-Lederer A; Lewis JD; Stark H
Source: Self-asserted source
Joe Lewis via Europe PubMed Central