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Organic chemistry, medicinal chemistry, chemical biology
United States

Activities

Employment (3)

University of Tennessee Health Science Center: Memphis, US

2024-08-01 to present | Associate Professor (Pharmaceutical Sciences)
Employment
Source: Self-asserted source
Sudeshna Roy

University of Mississippi: Oxford, US

2024-07-01 to 2024-07-31 | Associate Professor (BioMolecular Sciences)
Employment
Source: Self-asserted source
Sudeshna Roy

University of Mississippi: Oxford, US

2017-07-01 to 2024-06-30 | Assistant Professor (BioMolecular Sciences)
Employment
Source: Self-asserted source
Sudeshna Roy

Education and qualifications (1)

University of Missouri-St. Louis: St. Louis, MO, US

2007-08-05 to 2012-08-04 | PhD (Chemistry and Biochemistry)
Education
Source: Self-asserted source
Sudeshna Roy

Works (28)

Plant antibacterials: The challenges and opportunities

Heliyon
2024-05 | Journal article
Contributors: Tomayo Berida; Yemi Adekunle; Hannah Dada-Adegbola; Ayoub Kdimy; Satyajit Sarker
Source: check_circle
UTHSC - Digital Measures

The challenges and opportunities of developing small molecule inhibitors of MraY

Elsevier
2023 | Book chapter
Contributors: Destinee Manning; Tzu-Yu Huang; Tomayo Berida
Source: check_circle
UTHSC - Digital Measures

Discovery, Synthesis, and Optimization of 1,2,4-Triazolyl Pyridines Targeting \textitMycobacterium tuberculosis

ACS Infectious Diseases
2023-11 | Journal article
Contributors: Tomayo Berida; Samuel McKee; Shamba Chatterjee; Destinee Manning; Wei Li; Pankaj Pandey; Siddharth Tripathi; Yassin Mreyoud; Asya Smirnov; Robert Doerksen et al.
Source: check_circle
UTHSC - Digital Measures

Morpholine-mediated defluorinative cycloaddition of \textitgem -difluoroalkenes and organic azides

Beilstein Journal of Organic Chemistry
2023-10 | Journal article
Contributors: Tzu-Yu Huang; Mario Djugovski; Sweta Adhikari; Destinee Manning
Source: check_circle
UTHSC - Digital Measures
grade
Preferred source (of 2)‎

Morpholine-mediated defluorinative cycloaddition of gem-difluoroalkenes and organic azides

2023-06-29 | Preprint
Contributors: Tzu-Yu Huang; Mario Djugovski; Sweta Adhikari; Destinee Manning; Sudeshna Roy
Source: check_circle
Crossref

Small Molecules Targeting the RNA-Binding Protein HuR Inhibit Tumor Growth in Xenografts

Journal of Medicinal Chemistry
2023-02 | Journal article
Contributors: Xiaoqing Wu; Remya Ramesh; Jinan Wang; Youguang Zheng; Ahlam Armaly; Lanjing Wei; Minli Xing; Lan Lan; Fei Gao; Yinglong Miao et al.
Source: check_circle
UTHSC - Digital Measures
grade
Preferred source (of 2)‎

HuR inhibition reduces post-ischemic cardiac remodeling by dampening acute inflammatory gene expression and the innate immune response

2023-01 | Other
Contributors: Samuel Slone; Sarah Anthony; Lisa Green; Michelle Nieman; Perwez Alam; Xiaoqing Wu; Jeffrey Aube; Liang Xu; John Lorenz; A. Owens et al.
Source: check_circle
UTHSC - Digital Measures

HuR-dependent expression of Wisp1 is necessary for TGFβ-induced cardiac myofibroblast activity

Journal of Molecular and Cellular Cardiology
2023-01 | Journal article
Contributors: Lisa Green; Samuel Slone; Sarah Anthony; Adrienne Guarnieri; Sharon Parkins; Shannon Shearer; Michelle Nieman; Jeffrey Aube; Xiaoqing Wu; Liang Xu et al.
Source: check_circle
UTHSC - Digital Measures

Discovery, Synthesis, and Optimization of 1,2,4-Triazolyl Pyridines Targeting Mycobacterium tuberculosis

2022-11-15 | Preprint
Contributors: Sudeshna Roy; Tomayo Berida; Samuel R. McKee; Shamba Chatterjee; Wei Li; Pankaj Pandey; Siddharth K. Tripathi; Robert J Doerksen; Mary Jackson; Chrsitian Ducho et al.
Source: check_circle
Crossref

Identification of potential non-nucleoside MraY inhibitors for tuberculosis chemotherapy using structure-based virtual screening

Journal of Biomolecular Structure and Dynamics
2022-07 | Journal article
Contributors: Pankaj Pandey; Shamba Chatterjee; Tomayo Berida; Robert Doerksen
Source: check_circle
UTHSC - Digital Measures

Regioselective synthesis of 4-fluoro-1,5-disubstituted-1,2,3-triazoles from synthetic surrogates of α-fluoroalkynes

Chemical Communications
2020 | Journal article
Contributors: Sampad Jana; Sweta Adhikari; Michael Cox
Source: check_circle
UTHSC - Digital Measures
grade
Preferred source (of 2)‎

Optimization Rules for SARS-CoV-2 Mpro Antivirals: Ensemble Docking and Exploration of the Coronavirus Protease Active Site

Viruses
2020-08 | Journal article
Contributors: Shana Stoddard; Serena Stoddard; Benjamin Oelkers; Kennedi Fitts; Kellen Whalum; Kaylah Whalum; Alexander Hemphill; Jithin Manikonda; Linda Martinez; Elizabeth Riley et al.
Source: check_circle
UTHSC - Digital Measures
grade
Preferred source (of 2)‎

Targeting the interaction between RNA-binding protein HuR and FOXQ1 suppresses breast cancer invasion and metastasis

Communications Biology
2020-04 | Journal article
Contributors: Xiaoqing Wu; Gulhumay Gardashova; Lan Lan; Shuang Han; Cuncong Zhong; Rebecca Marquez; Lanjing Wei; Spencer Wood; Ragul Gowthaman; John Karanicolas et al.
Source: check_circle
UTHSC - Digital Measures
grade
Preferred source (of 2)‎

HuR Reduces Radiation-Induced DNA Damage by Enhancing Expression of ARID1A

Cancers
2019-12 | Journal article
Contributors: Daniel Andrade; Meghna Mehta; James Griffith; Sangphil Oh; Joshua Corbin; Anish Babu; Supriyo De; Allshine Chen; Yan Zhao; Sanam Husain et al.
Source: check_circle
UTHSC - Digital Measures

Regioselective synthesis of 4-fluoro-1,5-substituted-1,2,3-triazoles from synthetic surrogates of 1-fluoroalkynes

2019-12-02 | Other
Contributors: Sampad Jana; Sweta Adhikari; Michael Cox; Sudeshna Roy
Source: check_circle
Crossref

Regioselective synthesis of 4-fluoro-1,5-substituted-1,2,3-triazoles from synthetic surrogates of 1-fluoroalkynes

2019-12-02 | Other
Contributors: Sampad Jana; Sweta Adhikari; Michael Cox; Sudeshna Roy
Source: check_circle
Crossref

Fluorinated 1,2,3-Triazoles from α-Fluoronitroalkenes as Surrogates of α-Fluoroalkynes via Regioselective Cycloaddition Reactions with Organic Azides

2019-09-30 | Other
Contributors: Sampad Jana; Sweta Adhikari; Michael Cox; Sudeshna Roy
Source: check_circle
Crossref

Fluorinated 1,2,3-Triazoles from α-Fluoronitroalkenes as Surrogates of α-Fluoroalkynes via Regioselective Cycloaddition Reactions with Organic Azides

2019-09-03 | Other
Contributors: Sampad Jana; Sweta Adhikari; Michael Cox; Sudeshna Roy
Source: check_circle
Crossref

The HuR CMLD-2 inhibitor exhibits antitumor effects via MAD2 downregulation in thyroid cancer cells

Scientific Reports
2019-05 | Journal article
Contributors: Lorenzo Allegri; Federica Baldan; Jeffrey Aubé; Diego Russo; Sebastiano Filetti; Giuseppe Damante
Source: check_circle
UTHSC - Digital Measures

Human antigen R as a therapeutic target in pathological cardiac hypertrophy

JCI Insight
2019-02 | Journal article
Contributors: Lisa Green; Sarah Anthony; Samuel Slone; Lindsey Lanzillotta; Michelle Nieman; Xiaoqing Wu; Nathan Robbins; Shannon Jones; A. Owens; Jeffrey Aube et al.
Source: check_circle
UTHSC - Digital Measures
grade
Preferred source (of 2)‎

Identification of Antimalarial Inhibitors Using Late-Stage Gametocytes in a Phenotypic Live/Dead Assay

SLAS Discovery
2019-01 | Journal article
Contributors: Timothy Spicer; Donald Gardiner; Frank Schoenen; Patrick Griffin; Peter Chase; Louis Scampavia; Peter Hodder; Katharine Trenholme
Source: check_circle
UTHSC - Digital Measures

Hexafluoroisopropanol and Acetyl Chloride Promoted Catalytic Hydroarylation with Phenols

European Journal of Organic Chemistry
2018-01 | Journal article
Contributors: Hashim Motiwala; Karl Koshlap; Jeffrey Aubé
Source: check_circle
UTHSC - Digital Measures

\textitN ‐Phenylbenzamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore

ChemMedChem
2016-02 | Journal article
Contributors: Justina Šileikytė; Benjamin Neuenswander; Michael Hedrick; Thomas Chung; Jeffrey Aubé; Frank Schoenen; Michael Forte; Paolo Bernardi
Source: check_circle
UTHSC - Digital Measures

A Practical and Scalable Synthesis of (S)- and (R)-1-(Dimethoxyphosphoryl)allyl Methyl Carbonates

Synthesis
2015-10 | Journal article
Contributors: Nongnuch Sutivisedsak; Bruce Hamper; Alexander Lyss; Christopher Spilling
Source: check_circle
UTHSC - Digital Measures

Discovery, Synthesis, and Optimization of Diarylisoxazole‐3‐carboxamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore

ChemMedChem
2015-10 | Journal article
Contributors: Justina Šileikytė; Marco Schiavone; Benjamin Neuenswander; Francesco Argenton; Jeffrey Aubé; Michael Hedrick; Thomas Chung; Michael Forte; Paolo Bernardi; Frank Schoenen
Source: check_circle
UTHSC - Digital Measures

Development of ( \textitE )-2-((1,4-Dimethylpiperazin-2-ylidene)amino)-5-nitro- \textitN -phenylbenzamide, ML336: Novel 2-Amidinophenylbenzamides as Potent Inhibitors of Venezuelan Equine Encephalitis Virus

Journal of Medicinal Chemistry
2014-10 | Journal article
Contributors: Chad Schroeder; Tuanli Yao; Julie Sotsky; Robert Smith; Yong-Kyu Chu; Haixun Guo; Nichole Tower; James Noah; Sara McKellip; Melinda Sosa et al.
Source: check_circle
UTHSC - Digital Measures

An Expeditious Total Synthesis of Both Diastereoisomeric Lipid Dihydroxytetrahydrofurans from \textitNotheia anomala

Organic Letters
2012-05 | Journal article
Contributors: Christopher Spilling
Source: check_circle
UTHSC - Digital Measures

Synthesis of the C(18)−C(34) Fragment of Amphidinolide C and the C(18)−C(29) Fragment of Amphidinolide F

Organic Letters
2010-11 | Journal article
Contributors: Christopher Spilling
Source: check_circle
UTHSC - Digital Measures

Peer review (6 reviews for 6 publications/grants)

Review activity for ACS infectious diseases. (1)
Review activity for ACS medicinal chemistry letters. (1)
Review activity for Chemical research in toxicology. (1)
Review activity for Journal of natural products. (1)
Review activity for Nature communications (1)
Review activity for Organic letters. (1)