Personal information

metabolomics, GC-MS, protein nanovehicles, biocatalysis, green chemistry
Italy

Activities

Employment (2)

Sapienza University of Rome: Rome, Lazio, IT

2019-12-29 to present | Associate Professor (Department of Biochemical Sciences)
Employment
Source: Self-asserted source
Alberto Macone

Università degli Studi di Roma La Sapienza: Roma, Lazio, IT

2008-11-01 to present | Researcher (Dipartimento di Scienze Biochimiche "A. Rossi Fanelli")
Employment
Source: Self-asserted source
Alberto Macone

Education and qualifications (3)

Sapienza University of Rome: Rome, Lazio, IT

2004 to 2007 | Ph.D. in Biochemistry (Department of Biochemical Sciences)
Qualification
Source: Self-asserted source
Alberto Macone

Sapienza Università di Roma: Rome, IT

1998-10-01 to 2003-11-22 | Clninical Pathology residency
Education
Source: Self-asserted source
Alberto Macone

Università degli Studi di Roma La Sapienza: Roma, Lazio, IT

1989-10-01 to 1995-11-22 | master degree in Biological Sciences
Education
Source: Self-asserted source
Alberto Macone

Works (50 of 85)

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Page 1 of 2

Aged Garlic Extract (AGE) and Its Constituent S-Allyl-Cysteine (SAC) Inhibit the Expression of Pro-Inflammatory Genes Induced in Bronchial Epithelial IB3-1 Cells by Exposure to the SARS-CoV-2 Spike Protein and the BNT162b2 Vaccine

Molecules
2024-12-16 | Journal article
Contributors: Jessica Gasparello; Chiara Papi; Giovanni Marzaro; Alberto Macone; Matteo Zurlo; Alessia Finotti; Enzo Agostinelli; Roberto Gambari
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Off-Target Inhibition of Human Dihydroorotate Dehydrogenase (hDHODH) Highlights Challenges in the Development of Fat Mass and Obesity-Associated Protein (FTO) Inhibitors

ACS Pharmacology & Translational Science
2024-12-13 | Journal article
Contributors: Marco Tarullo; Guillermo Fernandez Rodriguez; Alessia Iaiza; Sara Venezia; Alberto Macone; Alessio Incocciati; Silvia Masciarelli; Marcella Marchioni; Marta Giorgis; Marco Lucio Lolli et al.
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Aged Garlic Extract (AGE) and Its Constituents S‐allyl‐cysteine (SAC) Inhibit the Expression of Pro‐Inflammatory Genes Induced in Bronchial Epithelial IB3‐1 Cells by Exposure to the SARS‐CoV‐2 Spike Protein and the BNT162b2 Vaccine

2024-11-08 | Preprint
Contributors: Jessica Gasparello; Chiara Papi; Giovanni Marzaro; Alberto Macone; Matteo Zurlo; Alessia Finotti; Enzo Agostinelli; Roberto Gambari
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A Solanum lycopersicum polyamine oxidase contributes to the control of plant growth, xylem differentiation, and drought stress tolerance

The Plant Journal
2024-07 | Journal article
Contributors: Riccardo D'Incà; Roberto Mattioli; Martina Tomasella; Raffaela Tavazza; Alberto Macone; Alessio Incocciati; Damiano Martignago; Fabio Polticelli; Ilaria Fraudentali; Alessandra Cona et al.
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Thymic-Epithelial-Cell-Dependent Microenvironment Influences Proliferation and Apoptosis of Leukemic Cells

International Journal of Molecular Sciences
2024-01-24 | Journal article
Contributors: Sandesh Kumar Patel; Nadezda Zhdanovskaya; Ilaria Sergio; Antonella Cardinale; Marco Rosichini; Claudia Varricchio; Eleonora Pace; Carlo Capalbo; Franco Locatelli; Alberto Macone et al.
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Hydrophobicity‐enhanced ferritin nanoparticles for efficient encapsulation and targeted delivery of hydrophobic drugs to tumor cells

Protein Science
2023-12 | Journal article
Contributors: Alessio Incocciati; Jan Kubeš; Roberta Piacentini; Chiara Cappelletti; Sofia Botta; Lucia Bertuccini; Tomáš Šimůnek; Alberto Boffi; Alberto Macone; Alessandra Bonamore
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Characterization of the Chemopreventive Properties of Cannabis sativa L. Inflorescences from Monoecious Cultivars Grown in Central Italy

Plants
2023-11-09 | Journal article
Contributors: Silvia Di Giacomo; Ester Percaccio; Annabella Vitalone; Cinzia Ingallina; Luisa Mannina; Alberto Macone; Antonella Di Sotto
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Harnessing Buffer Solutions to Modify the Association State of Ferritin Nanoparticles

Separations
2023-07-20 | Journal article
Contributors: Alessio Incocciati; Chiara Cappelletti; Alberto Boffi; Alberto Macone; Alessandra Bonamore
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Unlocking the Treasure Box: The Role of HEPES Buffer in Disassembling an Uncommon Ferritin Nanoparticle

Separations
2022-08-17 | Journal article
Contributors: Alessio Incocciati; Lucia Bertuccini; Alberto Boffi; Alberto Macone; Alessandra Bonamore
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Phytochemical Composition and Cytoprotective Properties of the Endemic Sideritis sipylea Boiss Greek Species: A Valorization Study

Pharmaceuticals
2022-08-11 | Journal article
Contributors: Silvia Di Giacomo; Antonella Di Sotto; Apostolis Angelis; Ester Percaccio; Annabella Vitalone; Marco Gullì; Alberto Macone; Evangelos Axiotis; Alexios Leandros Skaltsounis
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Immobilization of Lathyrus cicera Amine Oxidase on Magnetic Microparticles for Biocatalytic Applications

International Journal of Molecular Sciences
2022-06-10 | Journal article
Contributors: Elisa Di Fabio; Antonia Iazzetti; Alessio Incocciati; Valentina Caseli; Giancarlo Fabrizi; Alberto Boffi; Alessandra Bonamore; Alberto Macone
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Characterization of the Phytochemical Composition and Bioactivities of Anacyclus maroccanus Ball. and Anacyclus radiatus Loisel Aerial Parts: Preliminary Evidence for the Possible Development of Moroccan Plants

Molecules
2022-01-21 | Journal article
Contributors: Saida Sissi; Silvia Di Giacomo; Claudio Ferrante; Paola Angelini; Alberto Macone; Anna Maria Giusti; Chiara Toniolo; Annabella Vitalone; Aghraz Abdellah; Mustapha Larhsini et al.
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Rapid and Simultaneous Determination of Free Aromatic Carboxylic Acids and Phenols in Commercial Juices by GC-MS after Ethyl Chloroformate Derivatization

Separations
2021-12-30 | Journal article
Contributors: Alessio Incocciati; Elisa Di Fabio; Alberto Boffi; Alessandra Bonamore; Alberto Macone
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Tomato and Olive Bioactive Compounds: A Natural Shield against the Cellular Effects Induced by β-Hexachlorocyclohexane-Activated Signaling Pathways

Molecules
2021-11 | Journal article | Author
Contributors: Elisabetta Rubini; Marco Minacori; Giuliano Paglia; Alberto Macone; Silvia Chichiarelli; Fabio ALTIERI; Margherita EUFEMI
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Multidisciplinary Digital Publishing Institute
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Biocatalytic Production of Aldehydes: Exploring the Potential of Lathyrus cicera Amine Oxidase

Biomolecules
2021-10-18 | Journal article
Contributors: Elisa Di Fabio; Alessio Incocciati; Alberto Boffi; Alessandra Bonamore; Alberto Macone
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The Fatty Acid and Protein Profiles of Circulating CD81-Positive Small Extracellular Vesicles Are Associated with Disease Stage in Melanoma Patients

Cancers
2021-08-18 | Journal article
Contributors: Giovanni Paolino; Veronica Huber; Serena Camerini; Marialuisa Casella; Alberto Macone; Lucia Bertuccini; Francesca Iosi; Elisa Moliterni; Serena Cecchetti; Irene Ruspantini et al.
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The Emerging Role of Amino Acids of the Brain Microenvironment in the Process of Metastasis Formation

Cancers
2021-06-09 | Journal article
Contributors: Francesca Cutruzzolà; Amani Bouzidi; Francesca Romana Liberati; Sharon Spizzichino; Giovanna Boumis; Alberto Macone; Serena Rinaldo; Giorgio Giardina; Alessio Paone
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Fatty acid and proteomic signatures of circulating CD81 positive small extracellular vesicles define the disease stage in melanoma patients

2021-05-24 | Other
Contributors: Giovanni Paolino; Veronica Huber; Serena Camerini; Marialuisa Casella; Alberto Macone; Lucia Bertuccini; Francesca Iosi; Elisa Moliterni; Serena Cecchetti; Irene Ruspantini et al.
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β-Hexachlorocyclohexane: A Small Molecule with a Big Impact on Human Cellular Biochemistry

Biomedicines
2020-11-16 | Journal article
Contributors: Elisabetta Rubini; Giuliano Paglia; David Cannella; Alberto Macone; Antonella Di Sotto; Marco Gullì; Fabio Altieri; Margherita Eufemi
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Ethylchloroformate Derivatization for GC–MS Analysis of Resveratrol Isomers in Red Wine

Molecules
2020-10 | Journal article | Author
Contributors: Elisa Di Fabio; Alessio Incocciati; Federica Palombarini; Alberto Boffi; Alessandra Bonamore; Alberto Macone
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Multidisciplinary Digital Publishing Institute
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Dissecting the Cytochrome P450 OleP Substrate Specificity: Evidence for a Preferential Substrate

Biomolecules
2020-10-06 | Journal article
Contributors: Giacomo Parisi; Ida Freda; Cécile Exertier; Cristina Cecchetti; Elena Gugole; Gabriele Cerutti; Lucia D’Auria; Alberto Macone; Beatrice Vallone; Carmelinda Savino et al.
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Nanotechnology-Based Strategies to Develop New Anticancer Therapies

Biomolecules
2020-05-08 | Journal article
Contributors: Massimiliano Magro; Andrea Venerando; Alberto Macone; Gianluca Canettieri; Enzo Agostinelli; Fabio Vianello
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Modulation of STAT3 Signaling, Cell Redox Defenses and Cell Cycle Checkpoints by β-Caryophyllene in Cholangiocarcinoma Cells: Possible Mechanisms Accounting for Doxorubicin Chemosensitization and Chemoprevention

Cells
2020-04-02 | Journal article
Contributors: Antonella Di Sotto; Silvia Di Giacomo; Elisabetta Rubini; Alberto Macone; Marco Gulli; Caterina Loredana Mammola; Margherita Eufemi; Romina Mancinelli; Gabriela Mazzanti
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Ferritin Nanocages for Protein Delivery to Tumor Cells

Molecules
2020-02-13 | Journal article
Contributors: Federica Palombarini; Elisa Di Fabio; Alberto Boffi; Alberto Macone; Alessandra Bonamore
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Statins interfere with the attachment of S. cerevisiae mtDNA to the inner mitochondrial membrane

Journal of Enzyme Inhibition and Medicinal Chemistry
2020-01-01 | Journal article
Contributors: Angela Cirigliano; Antonia Amelina; Beatrice Biferali; Alberto Macone; Chiara Mozzetta; Michele Maria Bianchi; Mattia Mori; Bruno Botta; Elah Pick; Rodolfo Negri et al.
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Application of crossflow ultrafiltration for scaling up the purification of a recombinant ferritin

Protein Expression and Purification
2019 | Journal article
EID:

2-s2.0-85068569345

Contributors: Palombarini, F.; Ghirga, F.; Boffi, A.; Macone, A.; Bonamore, A.
Source: Self-asserted source
Alberto Macone via Scopus - Elsevier

Ergosterol reduction impairs mitochondrial DNA maintenance in S. cerevisiae

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
2019 | Journal article
EID:

2-s2.0-85058856892

Contributors: Cirigliano, A.; Macone, A.; Bianchi, M.M.; Oliaro-Bosso, S.; Balliano, G.; Negri, R.; Rinaldi, T.
Source: Self-asserted source
Alberto Macone via Scopus - Elsevier

Ferritin nanovehicle for targeted delivery of cytochrome C to cancer cells

Scientific Reports
2019 | Journal article
EID:

2-s2.0-85070764634

Contributors: Macone, A.; Masciarelli, S.; Palombarini, F.; Quaglio, D.; Boffi, A.; Trabuco, M.C.; Baiocco, P.; Fazi, F.; Bonamore, A.
Source: Self-asserted source
Alberto Macone via Scopus - Elsevier

Substrate-induced conformational change in cytochrome P450 OleP

FASEB Journal
2019 | Journal article
EID:

2-s2.0-85061063966

Contributors: Parisi, G.; Montemiglio, L.C.; Giuffrè, A.; Macone, A.; Scaglione, A.; Cerutti, G.; Exertier, C.; Savino, C.; Vallone, B.
Source: Self-asserted source
Alberto Macone via Scopus - Elsevier

The moonlighting RNA-binding activity of cytosolic serine hydroxymethyltransferase contributes to control compartmentalization of serine metabolism

Nucleic Acids Research
2019 | Journal article
EID:

2-s2.0-85067847112

Contributors: Guiducci, G.; Paone, A.; Tramonti, A.; Giardina, G.; Rinaldo, S.; Bouzidi, A.; Magnifico, M.C.; Marani, M.; Menendez, J.A.; Fatica, A. et al.
Source: Self-asserted source
Alberto Macone via Scopus - Elsevier

Linking Infection and Prostate Cancer Progression: Toll-like Receptor3 Stimulation Rewires Glucose Metabolism in Prostate Cells

Anticancer Research
2019-10 | Journal article
Part of ISSN: 0250-7005
Part of ISSN: 1791-7530
Source: Self-asserted source
Alberto Macone
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Gas Chromatographic–Mass Spectrometric Method for the Simultaneous Determination of Resveratrol Isomers and 2,4,6-Trihydroxyphenanthrene in Red Wines Exposed to UV-Light

Journal of Agricultural and Food Chemistry
2019-10-23 | Journal article
Contributors: Antonio Francioso; Lenka Laštovičková; Luciana Mosca; Alberto Boffi; Alessandra Bonamore; Alberto Macone
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Shmt2: A Stat3 Signaling New Player in Prostate Cancer Energy Metabolism

Cells
2019-09-06 | Journal article
Part of ISSN: 2073-4409
Source: Self-asserted source
Alberto Macone
grade
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Hypoglycemic, Antiglycation, and Cytoprotective Properties of a Phenol-Rich Extract From Waste Peel of Punica granatum L. var. Dente di Cavallo DC2

Molecules
2019-08-27 | Journal article
Contributors: Antonella Di Sotto; Marcello Locatelli; Alberto Macone; Chiara Toniolo; Stefania Cesa; Simone Carradori; Margherita Eufemi; Gabriela Mazzanti; Silvia Di Giacomo
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STAT3 Post-Translational Modifications Drive Cellular Signaling Pathways in Prostate Cancer Cells

International Journal of Molecular Sciences
2019-04-12 | Journal article
Contributors: Rossana Cocchiola; Elisabetta Rubini; Fabio Altieri; Silvia Chichiarelli; Giuliano Paglia; Donatella Romaniello; Stefania Carissimi; Alessandra Giorgi; Flavia Giamogante; Alberto Macone et al.
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Linear Cyclodextrin Polymer Prodrugs as Novel Therapeutics for Niemann-Pick Type C1 Disorder

Scientific Reports
2018 | Journal article
EID:

2-s2.0-85048964523

Contributors: Kulkarni, A.; Caporali, P.; Dolas, A.; Johny, S.; Goyal, S.; Dragotto, J.; Macone, A.; Jayaraman, R.; Fiorenza, M.T.
Source: Self-asserted source
Alberto Macone via Scopus - Elsevier

STAT3, a Hub Protein of Cellular Signaling Pathways, Is Triggered by β-Hexaclorocyclohexane

International Journal of Molecular Sciences
2018-07-20 | Journal article
Contributors: Elisabetta Rubini; Fabio Altieri; Silvia Chichiarelli; Flavia Giamogante; Stefania Carissimi; Giuliano Paglia; Alberto Macone; Margherita Eufemi
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Glucose metabolism in the progression of prostate cancer

Frontiers in Physiology
2017 | Journal article
EID:

2-s2.0-85014162527

Contributors: Cutruzzolà, F.; Giardina, G.; Marani, M.; Macone, A.; Paiardini, A.; Rinaldo, S.; Paone, A.
Source: Self-asserted source
Alberto Macone via Scopus - Elsevier

The Arabidopsis polyamine oxidase/dehydrogenase 5 interferes with cytokinin and auxin signaling pathways to control xylem differentiation

Journal of Experimental Botany
2017 | Journal article
EID:

2-s2.0-85019000707

Contributors: Alabdallah, O.; Ahou, A.; Mancuso, N.; Pompili, V.; Macone, A.; Pashkoulov, D.; Stano, P.; Cona, A.; Angelini, R.; Tavladoraki, P.
Source: Self-asserted source
Alberto Macone via Scopus - Elsevier

Green Routes for the Production of Enantiopure Benzylisoquinoline Alkaloids

International Journal of Molecular Sciences
2017-11 | Journal article
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Multidisciplinary Digital Publishing Institute
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A Novel Enzymatic Strategy for the Synthesis of Substituted Tetrahydroisoquinolines

ChemistrySelect
2016 | Journal article
EID:

2-s2.0-85029937881

Contributors: Bonamore, A.; Calisti, L.; Calcaterra, A.; Ismail, O.H.; Gargano, M.; D'Acquarica, I.; Botta, B.; Boffi, A.; Macone, A.
Source: Self-asserted source
Alberto Macone via Scopus - Elsevier

A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells

Oncotarget
2016 | Journal article
EID:

2-s2.0-84958012663

Contributors: Marani, M.; Paone, A.; Fiascarelli, A.; Macone, A.; Gargano, M.; Rinaldo, S.; Giardina, G.; Pontecorvi, V.; Koes, D.; McDermott, L. et al.
Source: Self-asserted source
Alberto Macone via Scopus - Elsevier

Influence of dietary vitamin E supplementation on cholesterol oxidation and fresh colour in beef aged for 3 and 14 days

Italian Journal of Animal Science
2016 | Journal article
EID:

2-s2.0-85048074578

Contributors: Vincenti, F.; Giusti, A.M.; Danieli, P.P.; Ronchi, B.; Perer, F.; Macone, A.; Filippi, E.; Iacurto, M.
Source: Self-asserted source
Alberto Macone via Scopus - Elsevier

Ternary Hybrid γ-Fe<inf>2</inf>O<inf>3</inf>/Cr<sup>VI</sup>/Amine Oxidase Nanostructure for Electrochemical Sensing: Application for Polyamine Detection in Tumor Tissue

Chemistry - A European Journal
2016 | Journal article
EID:

2-s2.0-84963773435

Contributors: Bonaiuto, E.; Magro, M.; Baratella, D.; Jakubec, P.; Sconcerle, E.; Terzo, M.; Miotto, G.; MacOne, A.; Agostinelli, E.; Fasolato, S. et al.
Source: Self-asserted source
Alberto Macone via Scopus - Elsevier

A novel enzyme with spermine oxidase properties in bovine liver mitochondria: Identification and kinetic characterization

Free Radical Biology and Medicine
2015 | Journal article
EID:

2-s2.0-84923555031

Contributors: Bonaiuto, E.; Grancara, S.; Martinis, P.; Stringaro, A.; Colone, M.; Agostinelli, E.; Macone, A.; Stevanato, R.; Vianello, F.; Toninello, A. et al.
Source: Self-asserted source
Alberto Macone via Scopus - Elsevier

Amine oxidase-based biosensors for spermine and spermidine determination

Analytical and Bioanalytical Chemistry
2015 | Journal article
EID:

2-s2.0-84938220367

Contributors: Boffi, A.; Favero, G.; Federico, R.; Macone, A.; Antiochia, R.; Tortolini, C.; Sanzó, G.; Mazzei, F.
Source: Self-asserted source
Alberto Macone via Scopus - Elsevier

Ethylene production in Botrytis cinerea- and oligogalacturonide-induced immunity requires calcium-dependent protein kinases

Plant Journal
2015 | Journal article
EID:

2-s2.0-84961340608

Contributors: Gravino, M.; Savatin, D.V.; MacOne, A.; De Lorenzo, G.
Source: Self-asserted source
Alberto Macone via Scopus - Elsevier

Non-canonical Hedgehog/AMPK-Mediated Control of Polyamine Metabolism Supports Neuronal and Medulloblastoma Cell Growth

Developmental Cell
2015 | Journal article
EID:

2-s2.0-84945252145

Contributors: D'Amico, D.; Antonucci, L.; Di Magno, L.; Coni, S.; Sdruscia, G.; Macone, A.; Miele, E.; Infante, P.; Di Marcotullio, L.; De Smaele, E. et al.
Source: Self-asserted source
Alberto Macone via Scopus - Elsevier

A plant spermine oxidase/dehydrogenase regulated by the proteasome and polyamines

Journal of Experimental Botany
2014 | Journal article
EID:

2-s2.0-84897431191

Contributors: Ahou, A.; Martignago, D.; Alabdallah, O.; Tavazza, R.; Stano, P.; Macone, A.; Pivato, M.; Masi, A.; Rambla, J.L.; Vera-Sirera, F. et al.
Source: Self-asserted source
Alberto Macone via Scopus - Elsevier

Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth

Cell Cycle
2014 | Journal article
EID:

2-s2.0-84915795126

Contributors: Di Magno, L.; Manzi, D.; D'Amico, D.; Coni, S.; Macone, A.; Infante, P.; Di Marcotullio, L.; De Smaele, E.; Ferretti, E.; Screpanti, I. et al.
Source: Self-asserted source
Alberto Macone via Scopus - Elsevier
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Page 1 of 2

Peer review (3 reviews for 3 publications/grants)

Review activity for ACS nano. (1)
Review activity for Catalysts. (1)
Review activity for Organic letters. (1)