Personal information

Other IDs

ResearcherID: K-5394-2018
Scopus Author ID: 56713056900

Keywords

RNA, Metabolism, sRNA, RNA-binding proteins, Post-transcriptional regulation, Mitochondria, Riboswitch

Countries

Spain, Netherlands

Activities

Collapse all

Employment (5)

Universidad Complutense de Madrid: Madrid, Comunidad de Madrid, ES

2017-11 to present | Assistant Professor (Department of Cell Biology)
Employment
Source: Self-asserted source
Alvaro D Ortega

University of Groningen: Groningen, Groningen, NL

2013-10 to 2017-09 | Postdoctoral researcher (Molecular Systems Biology)
Employment
Source: Self-asserted source
Alvaro D Ortega

Centro Nacional de Biotecnología: Madrid, Madrid, ES

2009-10 to 2013-09 | Post-doctoral researcher (Microbial biotechnology)
Employment
Source: Self-asserted source
Alvaro D Ortega

Centro de Investigación Biomédica en Red de Enfermedades Raras: Madrid, Madrid, ES

2008-05 to 2009-09 | Post-doctoral researcher
Employment
Source: Self-asserted source
Alvaro D Ortega

Universidad Autónoma de Madrid: Madrid, Madrid, ES

2003-01 to 2008-04 | PhD student (Molecular Biology)
Employment
Source: Self-asserted source
Alvaro D Ortega

Education and qualifications (2)

Universidad Autónoma de Madrid: Madrid, Madrid, ES

2003-01 to 2008-04 | PhD (Molecular Biology)
Education
Source: Self-asserted source
Alvaro D Ortega

Universidad Autónoma de Madrid: Madrid, Madrid, ES

1997-09 to 2002-07 | MSc (Molecular Biology)
Education
Source: Self-asserted source
Alvaro D Ortega

Works (24)

Rli51 Attenuates Transcription of the Listeria Pathogenicity Island 1 Gene mpl and Functions as a Trans-Acting sRNA in Intracellular Bacteria

International Journal of Molecular Sciences
2024-08-29 | Journal article
DOI: 10.3390/ijms25179380
Contributors: Álvaro Morón; Laura Ortiz-Miravalles; Marcos Peñalver; Francisco García-del Portillo; M. Graciela Pucciarelli; Alvaro Darío Ortega
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Real-Time Assessment of Intracellular Metabolites in Single Cells through RNA-Based Sensors

Biomolecules
2023-04-28 | Journal article
DOI: 10.3390/biom13050765
Contributors: Alvaro Darío Ortega
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Pathogenicity and virulence of Listeria monocytogenes: A trip from environmental to medical microbiology

Virulence
2021-12-31 | Journal article
DOI: 10.1080/21505594.2021.1975526
Contributors: Juan J. Quereda; Alvaro Morón-García; Carla Palacios-Gorba; Charlotte Dessaux; Francisco García-del Portillo; M. Graciela Pucciarelli; Alvaro D. Ortega
Source: check_circle
Crossref

A synthetic RNA-based biosensor for fructose-1,6-bisphosphate that reports glycolytic flux

Cell Chemical Biology
2021-11 | Journal article
DOI: 10.1016/j.chembiol.2021.04.006
Contributors: Alvaro Darío Ortega; Vakil Takhaveev; Silke Roelie Vedelaar; Yi Long; Neus Mestre-Farràs; Danny Incarnato; Franziska Ersoy; Lars Folke Olsen; Günter Mayer; Matthias Heinemann
Source: check_circle
Crossref

Assessment of the interaction between the flux-signaling metabolite fructose-1,6-bisphosphate and the bacterial transcription factors CggR and Cra.

Molecular microbiology
2018-08 | Journal article
DOI: 10.1111/mmi.14008
PMID: 29923648
Contributors: Bley Folly B; Ortega AD; Hubmann G; Bonsing-Vedelaar S; Wijma HJ; van der Meulen P; Milias-Argeitis A; Heinemann M
Source: Self-asserted source
Alvaro D Ortega via Europe PubMed Central

Metabolic-flux dependent regulation of microbial physiology.

Current opinion in microbiology
2018-04 | Journal article
DOI: 10.1016/j.mib.2017.10.029
PMID: 29154077
Contributors: Litsios A; Ortega ÁD; Wit EC; Heinemann M
Source: Self-asserted source
Alvaro D Ortega via Europe PubMed Central

Bacterial persistence is an active σS stress response to metabolic flux limitation.

Molecular systems biology
2016-09 | Journal article
DOI: 10.15252/msb.20166998
PMID: 27655400
PMC: PMC5043093
Contributors: Radzikowski JL; Vedelaar S; Siegel D; Ortega ÁD; Schmidt A; Heinemann M
Source: Self-asserted source
Alvaro D Ortega via Europe PubMed Central

Non-coding RNA regulation in pathogenic bacteria located inside eukaryotic cells.

Frontiers in cellular and infection microbiology
2014 | Journal article
DOI: 10.3389/fcimb.2014.00162
PMID: 25429360
PMC: PMC4228915
Contributors: Ortega AD; Quereda JJ; Pucciarelli MG; García-del Portillo F
Source: Self-asserted source
Alvaro D Ortega via Europe PubMed Central

The Listeria Small RNA Rli27 Regulates a Cell Wall Protein inside Eukaryotic Cells by Targeting a Long 5'-UTR Variant.

PLoS genetics
2014-10 | Journal article
DOI: 10.1371/journal.pgen.1004765
PMID: 25356775
PMC: PMC4214639
Contributors: Quereda JJ; Ortega AD; Pucciarelli MG; García-Del Portillo F
Source: Self-asserted source
Alvaro D Ortega via Europe PubMed Central

A novel antisense RNA from the Salmonella virulence plasmid pSLT expressed by non-growing bacteria inside eukaryotic cells.

PloS one
2013 | Journal article
DOI: 10.1371/journal.pone.0077939
PMID: 24205037
PMC: PMC3815029
Contributors: Gonzalo-Asensio J; Ortega AD; Rico-Pérez G; Pucciarelli MG; García-Del Portillo F
Source: Self-asserted source
Alvaro D Ortega via Europe PubMed Central

An RpoS-dependent sRNA regulates the expression of a chaperone involved in protein folding.

RNA (New York, N.Y.)
2013-09 | Journal article
DOI: 10.1261/rna.039537.113
PMID: 23893734
PMC: PMC3753932
Contributors: Silva IJ; Ortega AD; Viegas SC; García-Del Portillo F; Arraiano CM
Source: Self-asserted source
Alvaro D Ortega via Europe PubMed Central

Genome expression analysis of nonproliferating intracellular Salmonella enterica serovar Typhimurium unravels an acid pH-dependent PhoP-PhoQ response essential for dormancy.

Infection and immunity
2013-01 | Journal article
DOI: 10.1128/iai.01080-12
PMID: 23090959
PMC: PMC3536153
Contributors: Núñez-Hernández C; Tierrez A; Ortega AD; Pucciarelli MG; Godoy M; Eisman B; Casadesús J; García-del Portillo F
Source: Self-asserted source
Alvaro D Ortega via Europe PubMed Central

Dynamics of Salmonella small RNA expression in non-growing bacteria located inside eukaryotic cells.

RNA biology
2012-04 | Journal article
DOI: 10.4161/rna.19317
PMID: 22336761
Contributors: Ortega AD; Gonzalo-Asensio J; García-del Portillo F
Source: Self-asserted source
Alvaro D Ortega via Europe PubMed Central

Human G3BP1 interacts with beta-F1-ATPase mRNA and inhibits its translation.

Journal of cell science
2010-08 | Journal article
DOI: 10.1242/jcs.065920
PMID: 20663914
Contributors: Ortega AD; Willers IM; Sala S; Cuezva JM
Source: Self-asserted source
Alvaro D Ortega via Europe PubMed Central

Up-regulation of the ATPase inhibitory factor 1 (IF1) of the mitochondrial H+-ATP synthase in human tumors mediates the metabolic shift of cancer cells to a Warburg phenotype.

The Journal of biological chemistry
2010-08 | Journal article
DOI: 10.1074/jbc.m110.146480
PMID: 20538613
PMC: PMC2919093
Contributors: Sánchez-Cenizo L; Formentini L; Aldea M; Ortega AD; García-Huerta P; Sánchez-Aragó M; Cuezva JM
Source: Self-asserted source
Alvaro D Ortega via Europe PubMed Central

Selective inhibition of beta-F1-ATPase mRNA translation in human tumours.

The Biochemical journal
2010-03 | Journal article
DOI: 10.1042/bj20091570
PMID: 20028336
Contributors: Willers IM; Isidoro A; Ortega AD; Fernández PL; Cuezva JM
Source: Self-asserted source
Alvaro D Ortega via Europe PubMed Central

The tumor suppressor function of mitochondria: translation into the clinics.

Biochimica et biophysica acta
2009-12 | Journal article
DOI: 10.1016/j.bbadis.2009.01.006
PMID: 19419707
Contributors: Cuezva JM; Ortega AD; Willers I; Sánchez-Cenizo L; Aldea M; Sánchez-Aragó M
Source: Self-asserted source
Alvaro D Ortega via Europe PubMed Central

Cancer abolishes the tissue type-specific differences in the phenotype of energetic metabolism.

Translational oncology
2009-08 | Journal article
DOI: 10.1593/tlo.09106
PMID: 19701498
PMC: PMC2730139
Contributors: Acebo P; Giner D; Calvo P; Blanco-Rivero A; Ortega AD; Fernández PL; Roncador G; Fernández-Malavé E; Chamorro M; Cuezva JM
Source: Self-asserted source
Alvaro D Ortega via Europe PubMed Central

Glucose avidity of carcinomas.

Cancer letters
2009-04 | Journal article
DOI: 10.1016/j.canlet.2008.08.007
PMID: 18790562
Contributors: Ortega AD; Sánchez-Aragó M; Giner-Sánchez D; Sánchez-Cenizo L; Willers I; Cuezva JM
Source: Self-asserted source
Alvaro D Ortega via Europe PubMed Central

HuR and the bioenergetic signature of breast cancer: a low tumor expression of the RNA-binding protein predicts a higher risk of disease recurrence.

Carcinogenesis
2008-11 | Journal article
DOI: 10.1093/carcin/bgn185
PMID: 18687667
Contributors: Ortega AD; Sala S; Espinosa E; González-Barón M; Cuezva JM
Source: Self-asserted source
Alvaro D Ortega via Europe PubMed Central

Loss of the mitochondrial bioenergetic capacity underlies the glucose avidity of carcinomas.

Cancer research
2007-10 | Journal article
DOI: 10.1158/0008-5472.can-07-1678
PMID: 17909002
Contributors: López-Ríos F; Sánchez-Aragó M; García-García E; Ortega AD; Berrendero JR; Pozo-Rodríguez F; López-Encuentra A; Ballestín C; Cuezva JM
Source: Self-asserted source
Alvaro D Ortega via Europe PubMed Central

A message emerging from development: the repression of mitochondrial beta-F1-ATPase expression in cancer.

Journal of bioenergetics and biomembranes
2007-06 | Journal article
DOI: 10.1007/s10863-007-9087-9
PMID: 17712532
Contributors: Cuezva JM; Sánchez-Aragó M; Sala S; Blanco-Rivero A; Ortega AD
Source: Self-asserted source
Alvaro D Ortega via Europe PubMed Central

Biogenesis and dynamics of mitochondria during the cell cycle: significance of 3'UTRs.

PloS one
2006 | Journal article
DOI: 10.1371/journal.pone.0000107
PMID: 17205111
PMC: PMC1762426
Contributors: Martínez-Diez M; Santamaría G; Ortega AD; Cuezva JM
Source: Self-asserted source
Alvaro D Ortega via Europe PubMed Central

Alteration of the bioenergetic phenotype of mitochondria is a hallmark of breast, gastric, lung and oesophageal cancer.

The Biochemical journal
2004-02 | Journal article
DOI: 10.1042/bj20031541
PMID: 14683524
PMC: PMC1223948
Contributors: Isidoro A; Martínez M; Fernández PL; Ortega AD; Santamaría G; Chamorro M; Reed JC; Cuezva JM
Source: Self-asserted source
Alvaro D Ortega via Europe PubMed Central

Peer review (1 review for 1 publication/grant)

Review activity for Nature communications (1)
How many people are using ORCID?