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ResearcherID: C-9881-2013
Loop profile: 83390
Scopus Author ID: 55337618900
SciProfiles: 702362

Keywords

exosomes, catalytic antibodies, antibody polyreactivity, human milk, covid-19

Countries

Russia

Biography

Ph.D. in Biochemistry

Activities

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Employment (2)

Novosibirsk State University: Novosibirsk, RU

2009-09-01 to present | Researcher (Faculty of Natural Sciences)
Employment
Source: Self-asserted source
sirozha

Institute of Chemical Biology and Fundamental Medicine: Novosibirsk, RU

2006-09-01 to present | Researcher (Laboratory of Repair Enzymes)
Employment
Source: Self-asserted source
sirozha

Education and qualifications (1)

Novosibirsk State University: Novosibirsk, RU

2003-09-01 to 2008-06-30 | Master of Biology (Faculty of Natural Scinces)
Education
Source: Self-asserted source
sirozha

Funding (4)

Природные биспецифичные иммуноглобулины при ВИЧ-инфекции: анализ биологической активности и диагностического потенциала

2020-01-01 to 2020-12-31 | Grant
Russian Foundation for Basic Research (Moscow, RU)
URL: https://app.dimensions.ai/details/grant/grant.8719060
GRANT_NUMBER:

20-34-70115
Source: Self-asserted source
sirozha via DimensionsWizard

Analysis of the structural components of exosomes obtained from human and domestic animals milk

2018-01-01 to 2020-12-31 | Grant
Russian Science Foundation (Moscow, RU)
URL: https://app.dimensions.ai/details/grant/grant.8411693
GRANT_NUMBER: 18-74-10055
Source: Self-asserted source
sirozha via DimensionsWizard

Новые биохимические маркеры аутоиммунных патологий и патологий беременности – биспецифичные иммуноглобулины крови и плаценты человека

2016-01-01 to 2016-12-31 | Grant
Russian Foundation for Basic Research (Moscow, RU)
URL: https://app.dimensions.ai/details/grant/grant.6738179
GRANT_NUMBER: 16-34-60066
Source: Self-asserted source
sirozha via DimensionsWizard

Фактор молока человека, стимулирующий обмен иммуноглобулинов HL-фрагментами

2016-01-01 to 2016-12-31 | Grant
Russian Foundation for Basic Research (Moscow, RU)
URL: https://app.dimensions.ai/details/grant/grant.6739263
GRANT_NUMBER: 16-34-00163
Source: Self-asserted source
sirozha via DimensionsWizard

Works (50 of 72)

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Antibodies Specific to Rheumatologic and Neurologic Pathologies Found in Patient with Long COVID

Rheumato
2025-01-20 | Journal article
DOI: 10.3390/rheumato5010001
Contributors: Anna M. Timofeeva; Nataliya A. Klyaus; Sergey E. Sedykh; Georgy A. Nevinsky
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Catalase Activity of IgG and κκ-IgG, λλ-IgG, and κλ-IgG Subfractions in HIV-Infected Patients and Healthy Donors

Frontiers in Bioscience-Landmark
2024 | Journal article
DOI: 10.31083/J.FBL2905191
WOSUID: WOS:001238337400035
Contributors: Tolmacheva, Anna S.; Sedykh, Sergey E.; Onvumere, Margarita K.; Timofeeva, Anna M.; V. Maksimenko, Lada; Gashnikova, Natalya M.; Nevinsky, Georgy A.
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Investigation of Antibiotic Resistance of E. coli Associated with Farm Animal Feces with Participation of Citizen Scientists

Microorganisms
2024-11-13 | Journal article
DOI: 10.3390/microorganisms12112308
Contributors: Anna M. Timofeeva; Maria R. Galyamova; Dmitriy M. Krivosheev; Sergey Yu. Karabanov; Sergey E. Sedykh
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How Do Plant Growth-Promoting Bacteria Use Plant Hormones to Regulate Stress Reactions?

Plants
2024-08 | Journal article | Author
DOI: 10.3390/plants13172371
Contributors: Timofeeva Anna; Maria R. Galyamova; sirozha
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Multidisciplinary Digital Publishing Institute

Comparison of miR-106b, miR-191, and miR-30d expression dynamics in milk with regard to its composition in Holstein and Ayrshire cows

Animal Bioscience
2024-06-01 | Journal article
DOI: 10.5713/ab.23.0427
Contributors: Marina V. Pozovnikova; Viktoria B. Leibova; Olga V. Tulinova; Elena A. Romanova; Artem P. Dysin; Natalia V. Dementieva; Anastasiia I. Azovtseva; Sergey E. Sedykh
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Natural Antibodies Produced in Vaccinated Patients and COVID-19 Convalescents Hydrolyze Recombinant RBD and Nucleocapsid (N) Proteins

Biomedicines
2024-05 | Journal article | Author
DOI: 10.3390/biomedicines12051007
Contributors: Timofeeva Anna; Liliya Shayakhmetova; Артем Олегович Никитин; Tatyana Sedykh; Andrey Matveev; Даниил Шаньшин; Ekaterina A. Volosnikova; Iuliia Merkuleva; Dmitry Shcherbakov; Nina V. Tikunova et al.
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Multidisciplinary Digital Publishing Institute

Binding of Natural Antibodies Generated after COVID-19 and Vaccination with Individual Peptides Corresponding to the SARS-CoV-2 S-Protein

Vaccines
2024-04-17 | Journal article
DOI: 10.3390/vaccines12040426
Contributors: Anna M. Timofeeva; Sergey E. Sedykh; Ekaterina A. Litvinova; Sergey A. Dolgushin; Andrey L. Matveev; Nina V. Tikunova; Georgy A. Nevinsky
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Novel B-Cell Epitopes of Non-Neutralizing Antibodies in the Receptor-Binding Domain of the SARS-CoV-2 S-Protein with Different Effects on the Severity of COVID-19

Biochemistry. Biokhimiia
2023 | Journal article
DOI: 10.1134/S000629792309002X
WOSUID: WOS:001075625300002
Contributors: Matveev, Andrey L.; Pyankov, Oleg V.; Khlusevich, Yana A.; Tyazhelkova, Olga V.; Emelyanova, Ljudmila A.; Timofeeva, Anna M.; Shipovalov, Andrey V.; Chechushkov, Anton V.; Zaitseva, Natalia S.; Kudrov, Gleb A. et al.
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Scientific volunteering of students and organization of genetic research in agriculture

Tomsk State University Journal
2023 | Journal article
DOI: 10.17223/15617793/497/26
WOSUID: WOS:001200194800026
Contributors: Antsifirov, Sergey V.; Galyamova, Maria R.; Sedykh, Sergey E.; Gichgeldieva, Maya O.; Doroshenko, Alexander S.
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Plant Growth-Promoting Soil Bacteria: Nitrogen Fixation, Phosphate Solubilization, Siderophore Production, and Other Biological Activities

Plants
2023-12-05 | Journal article
DOI: 10.3390/plants12244074
Contributors: Anna M. Timofeeva; Maria R. Galyamova; Sergey E. Sedykh
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Plant Growth-Promoting Bacteria of Soil: Designing of Consortia Beneficial for Crop Production

Microorganisms
2023-11-26 | Journal article
DOI: 10.3390/microorganisms11122864
Contributors: Anna M. Timofeeva; Maria R. Galyamova; Sergey E. Sedykh
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Identification of Antibody-Mediated Hydrolysis Sites of Oligopeptides Corresponding to the SARS-CoV-2 S-Protein by MALDI-TOF Mass Spectrometry

International Journal of Molecular Sciences
2023-09-20 | Journal article
DOI: 10.3390/ijms241814342
Contributors: Anna M. Timofeeva; Sergey E. Sedykh; Pavel S. Dmitrenok; Georgy A. Nevinsky
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Natural Antibodies Produced in Vaccinated Patients and COVID-19 Convalescents Recognize and Hydrolyze Oligopeptides Corresponding to the S-Protein of SARS-CoV-2

Vaccines
2023-09-15 | Journal article
DOI: 10.3390/vaccines11091494
Contributors: Anna M. Timofeeva; Sergey E. Sedykh; Tatyana A. Sedykh; Georgy A. Nevinsky
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Isolation of Extracellular Vesicles of Holothuria (Sea Cucumber Eupentacta fraudatrix)

International Journal of Molecular Sciences
2023-08-17 | Journal article
DOI: 10.3390/ijms241612907
Contributors: Anastasiya V. Tupitsyna; Alina E. Grigorieva; Svetlana E. Soboleva; Nadezhda A. Maltseva; Sergey E. Sedykh; Julia Poletaeva; Pavel S. Dmitrenok; Elena I. Ryabchikova; Georgy A. Nevinsky
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Antibodies Capable of Enhancing SARS-CoV-2 Infection Can Circulate in Patients with Severe COVID-19

International Journal of Molecular Sciences
2023-06 | Journal article | Author
DOI: 10.3390/ijms241310799
Contributors: Andrey Matveev; Oleg Pyankov; Yana Khlusevich; Olga Tyazhelkova; Lyudmila Emelyanova; Timofeeva Anna; Andrey Shipovalov; Anton Chechushkov; Natalia Zaitseva; Gleb Kudrov et al.
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Multidisciplinary Digital Publishing Institute

Milk Exosomes: Next-Generation Agents for Delivery of Anticancer Drugs and Therapeutic Nucleic Acids

International Journal of Molecular Sciences
2023-06-15 | Journal article
DOI: 10.3390/ijms241210194
Contributors: Anna M. Timofeeva; Anastasia P. Paramonik; Sergey S. Sedykh; Georgy A. Nevinsky
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Catalase Activity of IgGs of Patients Infected with SARS-CoV-2

International Journal of Molecular Sciences
2023-06-13 | Journal article
DOI: 10.3390/ijms241210081
Contributors: Anna S. Tolmacheva; Margarita K. Onvumere; Sergey E. Sedykh; Anna M. Timofeeva; Georgy A. Nevinsky
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Antibody response to SARS-CoV-2 infection and Sputnik V vaccination

FEBS Open Bio
2022 | Journal article
WOSUID: WOS:000821444602093
Contributors: Timofeeva, A.; Sedykh, S.; Nevinsky, G.
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Immunological and biochemical changes in transgenic mice - a model of human multiple sclerosis

FEBS Open Bio
2022 | Journal article
WOSUID: WOS:000821444602098
Contributors: Aulova, K.; Urusov, A.; Sedykh, S.; Buneva, V.; Nevinsky, G.
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Microbe hunters - an educational program on soil microbiology and biochemistry for schoolchildren and their teachers

FEBS Open Bio
2022 | Journal article
WOSUID: WOS:000821444603217
Contributors: Paramonik, A.; Galyamova, M.; Voronina, E.; Sedykh, S.
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MicroRNA of the bovine milk lipid fraction

FEBS Open Bio
2022 | Journal article
WOSUID: WOS:000821444603058
Contributors: Paramonik, A.; Sedykh, S.; Nevinsky, G.
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SARS-CoV-2 infection as a risk factor for the development of autoimmune pathology

Molekulyarnaya Meditsina (Molecular medicine)
2022 | Journal article
DOI: 10.29296/24999490-2022-05-01
Contributors: Anna Mikhailovna Timofeeva; Sergey Evgenievich Sedykh; Georgy Alexandrovich Nevinsky
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Analysis of Proteins and Peptides of Highly Purified CD9+ and CD63+ Horse Milk Exosomes Isolated by Affinity Chromatography

International Journal of Molecular Sciences
2022-12-17 | Journal article
DOI: 10.3390/ijms232416106
Contributors: Sergey E. Sedykh; Lada V. Purvinsh; Evgeniya E. Burkova; Pavel S. Dmitrenok; Elena I. Ryabchikova; Georgy A. Nevinsky
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Bacterial Siderophores: Classification, Biosynthesis, Perspectives of Use in Agriculture

Plants
2022-11-12 | Journal article
DOI: 10.3390/plants11223065
Contributors: Anna M. Timofeeva; Maria R. Galyamova; Sergey E. Sedykh
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Natural IgG against S-Protein and RBD of SARS-CoV-2 Do Not Bind and Hydrolyze DNA and Are Not Autoimmune

International Journal of Molecular Sciences
2022-11-08 | Journal article
DOI: 10.3390/ijms232213681
Contributors: Anna M. Timofeeva; Sergey E. Sedykh; Evgeny A. Ermakov; Andrey L. Matveev; Eva I. Odegova; Tatiana A. Sedykh; Dmitry N. Shcherbakov; Iuliia A. Merkuleva; Ekaterina A. Volosnikova; Valentina S. Nesmeyanova et al.
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Prospects for Using Phosphate-Solubilizing Microorganisms as Natural Fertilizers in Agriculture

Plants
2022-08-15 | Journal article
DOI: 10.3390/plants11162119
Contributors: Anna Timofeeva; Maria Galyamova; Sergey Sedykh
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Milk exosomes as delivery agents for therapy of cancer diseases

Advances in Molecular Oncology
2022-06-24 | Journal article
DOI: 10.17650/2313-805X-2022-9-2-23-31
Contributors: S. E. Sedykh; A. M. Timofeeva; A. E. Kuleshova; G. A. Nevinskiy
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Cell Differentiation and Proliferation in the Bone Marrow and Other Organs of 2D2 Mice during Spontaneous Development of EAE Leading to the Production of Abzymes

Molecules
2022-03-28 | Journal article
DOI: 10.3390/molecules27072195
Contributors: Kseniya S. Aulova; Andrey E. Urusov; Ludmila B. Toporkova; Sergey E. Sedykh; Juliya A. Shevchenko; Valeriy P. Tereshchenko; Sergei V. Sennikov; Irina A. Orlovskaya; Georgy A. Nevinsky
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Post-Immune Antibodies in HIV-1 Infection in the Context of Vaccine Development: A Variety of Biological Functions and Catalytic Activities

Vaccines
2022-03-02 | Journal article
DOI: 10.3390/vaccines10030384
Contributors: Anna Timofeeva; Sergey Sedykh; Georgy Nevinsky
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Secretory immunoglobulin A from human milk hydrolyzes 5 histones and myelin basic protein

Journal of Dairy Science
2022-02 | Journal article
DOI: 10.3168/jds.2021-20917
Contributors: Ivan Yu. Kompaneets; Sergey E. Sedykh; Valentina N. Buneva; Pavel S. Dmitrenok; Georgy A. Nevinsky
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The Blood of the HIV-Infected Patients Contains κ-IgG, λ-IgG, and Bispecific κλ-IgG, Which Possess DNase and Amylolytic Activity

Life
2022-02-17 | Journal article
DOI: 10.3390/life12020304
Contributors: Anna Timofeeva; Sergey Sedykh; Lada Maksimenko; Tatyana Sedykh; Sergey Skudarnov; Tatyana Ostapova; Svetlana Yaschenko; Natalya Gashnikova; Georgy Nevinsky
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Antibodies from human milk hydrolyze microRNAs

FEBS Open Bio
2021 | Journal article
DOI: 10.1002/2211-5463.13205
WOSUID: WOS:000668898600355
Contributors: Kompaneets, I.; Ermakov, E.; Sedykh, S.; Nevinsky, G.
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Catalytic antibodies in the bone marrow and other organs of Th mice during spontaneous development of experimental autoimmune encephalomyelitis associated with cell differentiation

Molecular Biology Reports
2021 | Journal article
DOI: 10.1007/S11033-020-06117-8
WOSUID: WOS:000618917500002
Contributors: Aulova, Kseniya S.; Urusov, Andrey E.; Toporkova, Ludmila B.; Sedykh, Sergey E.; Shevchenko, Yuliya A.; Tereshchenko, Valery P.; Sennikov, Sergei V.; Budde, Thomas; Meuth, Sven G.; Orlovskaya, Irina A. et al.
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Human and horse milk extracellular vesicles: proteins and peptides

FEBS Open Bio
2021 | Journal article
WOSUID: WOS:000668898601357
Contributors: Sedykh, S.; Kuleshova, A.; Purvinsh, L.; Nevinsky, G.
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New biochemical markers of HIV infection - bispecific antibodies and its catalytic activity

FEBS Open Bio
2021 | Journal article
WOSUID: WOS:000668898602093
Contributors: Baranova, S.; Sedykh, S.; Nevinsky, G. A.
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Study of milk exosome nucleic acids

FEBS Open Bio
2021 | Journal article
WOSUID: WOS:000668898600352
Contributors: Kuleshova, A. E.; Purvinsh, L. V.; Burkova, E. E.; Sedykh, S. E.; Nevinsky, G. A.
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The association between EAE development in mice and the production of autoantibodies and abzymes after immunization of mice with different antigens

Journal of Cellular and Molecular Medicine
2021 | Journal article
DOI: 10.1111/JCMM.16183
WOSUID: WOS:000616352100001
Contributors: Aulova, Kseniya S.; Urusov, Andrey A.; Sedykh, Sergey E.; Toporkova, Ludmila B.; Lopatnikova, Julia A.; Buneva, Valentina N.; Sennikov, Sergei V.; Budde, Thomas; Meuth, Sven G.; Popova, Nelly A. et al.
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Analysis of peptides and small proteins in preparations of horse milk exosomes, purified on anti-CD81-Sepharose

International Dairy Journal
2021-06 | Journal article
DOI: 10.1016/j.idairyj.2021.104994
Contributors: Sergey E. Sedykh; Lada V. Purvinish; Evgeniya E. Burkova; Pavel S. Dmitrenok; Valentin V. Vlassov; Elena I. Ryabchikova; Georgy A. Nevinsky
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Human Placenta Exosomes: Biogenesis, Isolation, Composition, and Prospects for Use in Diagnostics

International Journal of Molecular Sciences
2021-02-22 | Journal article
DOI: 10.3390/ijms22042158
Contributors: Evgeniya E. Burkova; Sergey E. Sedykh; Georgy A. Nevinsky
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HIV-Infected Patients: Cross Site-Specific Hydrolysis of H3 and H4 Histones and Myelin Basic Protein with Antibodies against These Three Proteins

Molecules
2021-01-09 | Journal article
DOI: 10.3390/molecules26020316
Contributors: Svetlana V. Baranova; Pavel S. Dmitrenok; Valentina N. Buneva; Sergey E. Sedykh; Georgy A. Nevinsky
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How Human H1 Histone Recognizes DNA

Molecules
2020-10-05 | Journal article
DOI: 10.3390/molecules25194556
Contributors: Olesya P. Luzhetskaya; Sergey E. Sedykh; Georgy A. Nevinsky
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Milk Exosomes: Perspective Agents for Anticancer Drug Delivery

International Journal of Molecular Sciences
2020-09-11 | Journal article
DOI: 10.3390/ijms21186646
Contributors: Sergey Sedykh; Anna Kuleshova; Georgy Nevinsky
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Secretory immunoglobulin A from human milk hydrolyzes microRNA

Journal of Dairy Science
2020-08 | Journal article
DOI: 10.3168/jds.2019-17823
Contributors: Ivan Y. Kompaneets; Evgeny A. Ermakov; Sergey E. Sedykh; Valentina N. Buneva; Georgy A. Nevinsky
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IgGs from Human Milk Hydrolyze microRNAs

Molecules
2020-05-20 | Journal article
DOI: 10.3390/molecules25102366
Contributors: Ivan Yu. Kompaneets; Evgeny A. Ermakov; Sergey E. Sedykh; Valentina N. Buneva; Georgy A. Nevinsky
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Analysis of proteins and peptides of milk exosomes

FEBS Open Bio
2019 | Journal article
WOSUID: WOS:000486972406118
Contributors: Purvinsh, L.; Sedykh, S.; Nevinsky, G.
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DNase and RNase activities of fresh cow milk lactoferrin

Journal of Molecular Recognition
2019 | Journal article
DOI: 10.1002/JMR.2777
WOSUID: WOS:000473668400001
Contributors: Soboleva, Svetlana E.; Zakharova, Ol'ga D.; Sedykh, Sergey E.; Ivanisenko, Nikita, V; Buneva, Valentina N.; Nevinsky, Georgy A.
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MicroRNA content in human milk exosomes: isolation, detection, normalization

FEBS Open Bio
2019 | Journal article
WOSUID: WOS:000486972403151
Contributors: Sedykh, S.; Purvinsh, L.; Nevinsky, G.
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Production of Abzymes in Th, CBA, and C57BL/6 Mice before and after MOG Treatment: Comparing Changes in Cell Differentiation and Proliferation

Biomolecules
2019-12-28 | Journal article
DOI: 10.3390/biom10010053
Contributors: Kseniya S. Aulova; Andrey E. Urusov; Ludmila B. Toporkova; Sergey E. Sedykh; Yuliya A. Shevchenko; Valery P. Tereshchenko; Sergei V. Sennikov; Thomas Budde; Sven G. Meuth; Nelly A. Popova et al.
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Extra Purified Exosomes from Human Placenta Contain an Unpredictable Small Number of Different Major Proteins

International Journal of Molecular Sciences
2019-05 | Journal article | Author
DOI: 10.3390/ijms20102434
Contributors: Evgeniya E. Burkova; Alina E. Grigor’eva; Dmitrii V. Bulgakov; Pavel S. Dmitrenok; Valentin V. Vlassov; Elena Ryabchikova; sirozha; Georgy A. Nevinsky
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Cow Milk Lactoferrin Possesses Several Catalytic Activities

Biomolecules
2019-05-29 | Journal article
DOI: 10.3390/biom9060208
Contributors: Svetlana Soboleva; Sergey Sedykh; Ludmila Alinovskaya; Valentina Buneva; Georgy Nevinsky
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Peer review (444 reviews for 66 publications/grants)

Review activity for Access microbiology. (1)
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