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Works (24)

Targeting the P2Y13 Receptor Suppresses IL-33 and HMGB1 Release and Ameliorates Experimental Asthma

American Journal of Respiratory and Critical Care Medicine
2022-02-01 | Journal article
Contributors: Rhiannon B. Werder; Md Ashik Ullah; Muhammed Mahfuzur Rahman; Jennifer Simpson; Jason P. Lynch; Natasha Collinson; Sonja Rittchen; Ridwan B. Rashid; Md Al Amin Sikder; Herlina Y. Handoko et al.
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Crossref

HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling

PLOS Pathogens
2020-07-13 | Journal article
Contributors: Zhixuan Loh; Mark T. Heise; Jennifer Simpson; Ashik Ullah; Vivian Zhang; Wan J. Gan; Jason P. Lynch; Rhiannon B. Werder; Al Amin Sikder; Katie Lane et al.
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Crossref

Chronic IL-33 expression predisposes to virus-induced asthma exacerbations by increasing type 2 inflammation and dampening antiviral immunity

Journal of Allergy and Clinical Immunology
2018 | Journal article
EID:

2-s2.0-85033460423

Contributors: Werder, R.B.; Zhang, V.; Lynch, J.P.; Snape, N.; Upham, J.W.; Spann, K.; Phipps, S.
Source: Self-asserted source
Jason Lynch via Scopus - Elsevier

Host-pathogen interactions: What the EHEC are we learning from host genome-wide screens?

mBio
2018 | Journal article
EID:

2-s2.0-85054777199

Contributors: Lynch, J.P.; Lesser, C.F.
Source: Self-asserted source
Jason Lynch via Scopus - Elsevier

PGD2/DP2 receptor activation promotes severe viral bronchiolitis by suppressing IFN-λ production.

Science translational medicine
2018-05-01 | Journal article
Source: Self-asserted source
Jason Lynch
grade
Preferred source (of 2)‎

Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a–mediated T reg expansion

Journal of Experimental Medicine
2018-02-05 | Journal article
Contributors: Jason P. Lynch; Rhiannon B. Werder; Zhixuan Loh; Md. Al Amin Sikder; Bodie Curren; Vivian Zhang; Matthew J. Rogers; Katie Lane; Jennifer Simpson; Stuart B. Mazzone et al.
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Crossref
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Critical role of plasmacytoid dendritic cells in regulating gene expression and innate immune responses to human rhinovirus-16

Frontiers in Immunology
2017 | Journal article
EID:

2-s2.0-85032171740

Contributors: Xi, Y.; Troy, N.M.; Anderson, D.; Pena, O.M.; Lynch, J.P.; Phipps, S.; Bosco, A.; Upham, J.W.
Source: Self-asserted source
Jason Lynch via Scopus - Elsevier

The influence of the microbiome on early-life severe viral lower respiratory infections and asthma-Food for thought?

Frontiers in Immunology
2017 | Journal article
EID:

2-s2.0-85014418684

Contributors: Lynch, J.P.; Sikder, M.A.A.; Curren, B.F.; Werder, R.B.; Simpson, J.; Cuív, P.; Dennis, P.G.; Everard, M.L.; Phipps, S.
Source: Self-asserted source
Jason Lynch via Scopus - Elsevier

The Absence of Interferon-β Promotor Stimulator-1 (IPS-1) Predisposes to Bronchiolitis and Asthma-like Pathology in Response to Pneumoviral Infection in Mice

Scientific Reports
2017-05-24 | Journal article
Contributors: Jennifer Simpson; Jason P. Lynch; Zhixuan Loh; Vivian Zhang; Rhiannon B. Werder; Kirsten Spann; Simon Phipps
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Crossref
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Aeroallergen-induced IL-33 predisposes to respiratory virus–induced asthma by dampening antiviral immunity

Journal of Allergy and Clinical Immunology
2016 | Journal article
EID:

2-s2.0-84973444977

Contributors: Lynch, J.P.; Werder, R.B.; Simpson, J.; Loh, Z.; Zhang, V.; Haque, A.; Spann, K.; Sly, P.D.; Mazzone, S.B.; Upham, J.W. et al.
Source: Self-asserted source
Jason Lynch via Scopus - Elsevier

Th2/Th17 reciprocal regulation: Twists and turns in the complexity of asthma phenotypes

Annals of Translational Medicine
2016 | Journal article
EID:

2-s2.0-85011356939

Contributors: Lynch, J.P.; Ferreira, M.A.; Phipps, S.
Source: Self-asserted source
Jason Lynch via Scopus - Elsevier

AEROALLERGEN-INDUCED IL-33 PREDISPOSES TO RESPIRATORY VIRUS-INDUCED ASTHMA BY DAMPENING TYPE I AND III INTERFERON PRODUCTION

Respirology
2015 | Journal article
WOSUID:

WOS:000351464400368

Contributors: Werder, R.; Lynch, J.; Simpson, J.; Loh, Z.; Zhang, V; Spann, K.; Sly, P.; Mazzone, S.; Upham, J.; Phipps, S.
Source: Self-asserted source
Jason Lynch via ResearcherID

Immunomodulation of Airway Epithelium Cell Activation by Mesenchymal Stromal Cells Ameliorates House Dust Mite-Induced Airway Inflammation in Mice

American Journal of Respiratory Cell and Molecular Biology
2015 | Journal article
WOSUID:

WOS:000368418700004

Contributors: Duong, Khang M.; Arikkatt, Jaisy; Ullah, M. Ashik; Lynch, Jason P.; Zhang, Vivian; Atkinson, Kerry; Sly, Peter D.; Phipps, Simon
Source: Self-asserted source
Jason Lynch via ResearcherID
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INTERFERON REGULATORY FACTOR 7 PROTECTS AGAINST PNEUMOVIRUS-INDUCED AIRWAY SMOOTH MUSCLE GROWTH IN EARLY LIFE

Respirology
2015 | Journal article
WOSUID:

WOS:000351464400068

Contributors: Loh, Z.; Ullah, A.; Zhang, V; Lynch, J.; Werder, R.; Simpson, J.; Upham, J.; Mazzone, S.; Spann, K.; Phipps, S.
Source: Self-asserted source
Jason Lynch via ResearcherID

PDC EXPANSION OF NTREG LIMITS SEVERE PNEUMOVIRUS-INDUCED BRONCHIOLITIS AND ATTENUATES THE ONSET OF VIRUS-PROVOKED ASTHMA

Respirology
2015 | Journal article
WOSUID:

WOS:000351464400367

Contributors: Lynch, J.; Rogers, M.; Lane, K.; Werder, R.; Loh, Z.; Diener, K.; Hayball, J.; Hill, G.; Haque, A.; Spann, K. et al.
Source: Self-asserted source
Jason Lynch via ResearcherID

Regulatory T Cells Prevent Inducible BALT Formation by Dampening Neutrophilic Inflammation

Journal of Immunology
2015 | Journal article
WOSUID:

WOS:000353727400055

Contributors: Foo, Shen Yun; Zhang, Vivian; Lalwani, Amit; Lynch, Jason P.; Zhuang, Aowen; Lam, Chuan En; Foster, Paul S.; King, Cecile; Steptoe, Raymond J.; Mazzone, Stuart B. et al.
Source: Self-asserted source
Jason Lynch via ResearcherID
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Anti-IL-33 ameliorates asthma onset and progression in response to virus and allergen co-exposure

Immunology
2014 | Journal article
WOSUID:

WOS:000345702600087

Contributors: Lynch, J.; Werder, R. B.; Simpson, J.; Loh, Z.; Zhang, V.; Sly, P. D.; Mazzone, S.; Upham, J. W.; Phipps, S.
Source: Self-asserted source
Jason Lynch via ResearcherID

Critical role for IL-33 in the onset and progression of experimental asthma induced by concomitant virus infection and allergen exposure

Cytokine
2014 | Journal article
WOSUID:

WOS:000343021700226

Contributors: Werder, Rhiannon B.; Lynch, Jason P.; Simpson, Jennifer; Loh, Ken; Zhang, Vivian; Spann, Kirsten; Sly, Peter D.; Mazzone, Stuart; Upham, John W.; Phipps, Simon
Source: Self-asserted source
Jason Lynch via ResearcherID

IRF-3, IRF-7, and IPS-1 Promote Host Defense against Acute Human Metapneumovirus Infection in Neonatal Mice

American Journal of Pathology
2014 | Journal article
WOSUID:

WOS:000336948700017

Contributors: Spann, Kirsten M.; Loh, Zhixuan; Lynch, Jason P.; Ullah, Ashik; Zhang, Vivian; Baturcam, Engin; Werder, Rhiannon B.; Khajornjiraphan, Natthida; Rudd, Penny; Loo, Yeuh-Ming et al.
Source: Self-asserted source
Jason Lynch via ResearcherID
grade
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pDC expansion of nTreg limits severe Pneumovirus-induced bronchiolitis and attenuates the onset of virus-provoked asthma

Immunology
2014 | Journal article
WOSUID:

WOS:000345702600360

Contributors: Lynch, J. P.; Werder, R. B.; Rogers, M. J.; Lane, K.; Loh, Z.; Simpson, J.; Diener, K.; Hayball, J.; Zhang, P.; Swiecki, M. et al.
Source: Self-asserted source
Jason Lynch via ResearcherID

The plasmacytoid dendritic cell: at the cross-roads in asthma

European Respiratory Journal
2014 | Journal article
WOSUID:

WOS:000329552200032

Contributors: Lynch, Jason P.; Mazzone, Stuart B.; Rogers, Matthew J.; Arikkatt, Jaisy J.; Loh, Zhixuan; Pritchard, Antonia L.; Upham, John W.; Phipps, Simon
Source: Self-asserted source
Jason Lynch via ResearcherID
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HMGB1-RAGE AXIS MEDIATES HOUSE DUST MITE INDUCED ALLERGIC SENSITIZATION AND AIRWAY INFLAMMATION

Respirology
2013 | Journal article
WOSUID:

WOS:000315589700089

Contributors: Ullah, M. A.; Loh, Z.; Gan, W. J.; Zhang, V.; Lynch, J.; Eacharath, J.; Hughes, J. M.; Armour, C. L.; Phipps, S.; Sukkar, M. B.
Source: Self-asserted source
Jason Lynch via ResearcherID

The receptor for complement component C3a mediates protection from intestinal ischemia-reperfusion injuries by inhibiting neutrophil mobilization

Proceedings of the National Academy of Sciences of the United States of America
2013 | Journal article
WOSUID:

WOS:000320503000058

Contributors: Wu, Mike C. L.; Brennan, Faith H.; Lynch, Jason P. L.; Mantovani, Susanna; Phipps, Simon; Wetsel, Rick A.; Ruitenberg, Marc J.; Taylor, Stephen M.; Woodruff, Trent M.
Source: Self-asserted source
Jason Lynch via ResearcherID
grade
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Toll-like receptor 7 gene deficiency and early-life Pneumovirus infection interact to predispose toward the development of asthma-like pathology in mice

Journal of Allergy and Clinical Immunology
2013 | Journal article
WOSUID:

WOS:000318912200009

Contributors: Kaiko, Gerard E.; Loh, Zhixuan; Spann, Kirsten; Lynch, Jason P.; Lalwani, Amit; Zheng, Zhenglong; Davidson, Sophia; Uematsu, Satoshi; Akira, Shizuo; Hayball, John et al.
Source: Self-asserted source
Jason Lynch via ResearcherID
grade
Preferred source (of 2)‎

Peer review (1 review for 1 publication/grant)

Review activity for Communications biology. (1)