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Italy

Activities

Employment (4)

University of Padua: Padova, Padova - PD, IT

2023-03-08 to present | PhD (Assistant Professor)
Employment
Source: Self-asserted source
Emanuela Ruggiero

Università degli Studi di Padova Scuola di Medicina e Chirurgia: Padova, Veneto, IT

2016-05-01 to 2023-03-07 | Postdoctoral fellow (Diaprtimento di Medicina Molecolare)
Employment
Source: Self-asserted source
Emanuela Ruggiero

Università di Padova : Padova, IT

2015-11-01 to 2016-04-30 | Research Fellow (Dipartimento di Medicina Molecolare)
Employment
Source: Self-asserted source
Emanuela Ruggiero

Università di Ferrara : Ferrara, Emilia Romagna, IT

2014-02-15 to 2015-07-31 | Research Fellow (Department of Chemical and Pharmaceutical Sciences)
Employment
Source: Self-asserted source
Emanuela Ruggiero

Education and qualifications (3)

Universita degli Studi di Ferrara: Ferrara, Emilia-Romagna, IT

2011-01-01 to 2014-03-26 | PhD (Dipartimento di Scienze Chimiche e Farmaceutiche)
Education
Source: Self-asserted source
Emanuela Ruggiero

Università degli Studi di Napoli Federico II: Napoli, Campania, IT

2005-10-01 to 2010-07-23 | Laurea specialistica in Chimica e Tecnologia Farmaceutiche (Chimica Farmaceutica e Tossicologica)
Education
Source: Self-asserted source
Emanuela Ruggiero

Universidad de Alcalá de Henares: Alcalà de Henares, ES

2008-09-20 to 2009-05-20 | Erasmus student (Facultad de Farmacia)
Education
Source: Self-asserted source
Emanuela Ruggiero

Professional activities (2)

European Society of Clinical Microbiology and Infectious Diseases: Basel, Basel-Stadt, CH

2020-09-14 to present | Young Scientist
Membership
Source: Self-asserted source
Emanuela Ruggiero

International Society of Nucleotides, Nucleosides and Nucleic Acids: Baltimore, Maryland, US

2017-05-08 to present | Postdoc Membership
Membership
Source: Self-asserted source
Emanuela Ruggiero

Funding (1)

ESCMID Research Grant 2021

Source: Self-asserted source
Emanuela Ruggiero

Works (20)

G-quadruplexes in an SVA retrotransposon cause aberrant TAF1 gene expression in X-linked dystonia parkinsonism

Nucleic Acids Research
2024-10-28 | Journal article
Contributors: Giulia Nicoletto; Marianna Terreri; Ilaria Maurizio; Emanuela Ruggiero; Filippo M Cernilogar; Christine A Vaine; Maria Vittoria Cottini; Irina Shcherbakova; Ellen B Penney; Irene Gallina et al.
Source: check_circle
Crossref

Human genomic DNA is widely interspersed with i-motif structures

The EMBO Journal
2024-08-29 | Journal article
Contributors: Cristian David Peña Martinez; Mahdi Zeraati; Romain Rouet; Ohan Mazigi; Jake Y Henry; Brian Gloss; Jessica A Kretzmann; Cameron W Evans; Emanuela Ruggiero; Irene Zanin et al.
Source: check_circle
Crossref

Genome-wide mapping of i-motifs reveals their association with transcription regulation in live human cells

Nucleic Acids Research
2023-09-08 | Journal article
Contributors: Irene Zanin; Emanuela Ruggiero; Giulia Nicoletto; Sara Lago; Ilaria Maurizio; Irene Gallina; Sara N Richter
Source: check_circle
Crossref

Human Virus Genomes Are Enriched in Conserved Adenine/Thymine/Uracil Multiple Tracts That Pause Polymerase Progression

Frontiers in Microbiology
2022-06-01 | Journal article
Part of ISSN: 1664-302X
Source: Self-asserted source
Emanuela Ruggiero

Fused in Liposarcoma Protein, a New Player in the Regulation of HIV-1 Transcription, Binds to Known and Newly Identified LTR G-Quadruplexes

ACS Infectious Diseases
2022-05-13 | Journal article
Contributors: Emanuela Ruggiero; Ilaria Frasson; Elena Tosoni; Matteo Scalabrin; Rosalba Perrone; Maja Marušič; Janez Plavec; Sara N. Richter
Source: check_circle
Crossref

G-Quadruplex Targeting in the Fight against Viruses: An Update

International Journal of Molecular Sciences
2021-10-12 | Journal article
Contributors: Emanuela Ruggiero; Irene Zanin; Marianna Terreri; Sara N. Richter
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Antiviral Activity of the G-Quadruplex Ligand TMPyP4 against Herpes Simplex Virus-1

Viruses
2021-01-28 | Journal article
Contributors: Sara Artusi; Emanuela Ruggiero; Matteo Nadai; Beatrice Tosoni; Rosalba Perrone; Annalisa Ferino; Irene Zanin; Luigi Xodo; Louis Flamand; Sara N. Richter
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

The MDM2 inducible promoter folds into four-tetrad antiparallel G-quadruplexes targetable to fight malignant liposarcoma

Nucleic Acids Research
2021-01-25 | Journal article
Contributors: Sara Lago; Matteo Nadai; Emanuela Ruggiero; Martina Tassinari; Maja Marušič; Beatrice Tosoni; Ilaria Frasson; Filippo M Cernilogar; Valentina Pirota; Filippo Doria et al.
Source: check_circle
Crossref

Viral G-quadruplexes: New frontiers in virus pathogenesis and antiviral therapy

Annual Reports in Medicinal Chemistry
2020 | Book chapter
Part of ISSN: 0065-7743
Source: Self-asserted source
Emanuela Ruggiero

A dynamic i-motif with a duplex stem-loop in the long terminal repeat promoter of the HIV-1 proviral genome modulates viral transcription

Nucleic Acids Research
2019-12-02 | Journal article
Contributors: Emanuela Ruggiero; Sara Lago; Primož Šket; Matteo Nadai; Ilaria Frasson; Janez Plavec; Sara N Richter
Source: check_circle
Crossref

Stable and Conserved G-Quadruplexes in the Long Terminal Repeat Promoter of Retroviruses

ACS Infectious Diseases
2019-07-12 | Journal article
Contributors: Emanuela Ruggiero; Martina Tassinari; Rosalba Perrone; Matteo Nadai; Sara N. Richter
Source: check_circle
Crossref

G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy

Nucleic Acids Research
2018-04-20 | Journal article
Contributors: Emanuela Ruggiero; Sara N Richter
Source: check_circle
Crossref

Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors.

Journal of medicinal chemistry
2018-01 | Journal article
Contributors: Aghazadeh Tabrizi M; Baraldi PG; Baraldi S; Ruggiero E; De Stefano L; Rizzolio F; Di Cesare Mannelli L; Ghelardini C; Chicca A; Lapillo M et al.
Source: Self-asserted source
Emanuela Ruggiero via Europe PubMed Central

The cellular protein hnRNP A2/B1 enhances HIV-1 transcription by unfolding LTR promoter G-quadruplexes

Scientific Reports
2017 | Journal article
EID:

2-s2.0-85016137546

Contributors: Scalabrin, M.; Frasson, I.; Ruggiero, E.; Perrone, R.; Tosoni, E.; Lago, S.; Tassinari, M.; Palù, G.; Richter, S.N.
Source: Self-asserted source
Emanuela Ruggiero via Scopus - Elsevier
grade
Preferred source (of 2)‎

Synthesis and structure activity relationship investigation of triazolo[1,5-a]pyrimidines as CB<inf>2</inf> cannabinoid receptor inverse agonists

European Journal of Medicinal Chemistry
2016 | Journal article
EID:

2-s2.0-84959131120

Contributors: Aghazadeh Tabrizi, M.; Baraldi, P.G.; Ruggiero, E.; Saponaro, G.; Baraldi, S.; Poli, G.; Tuccinardi, T.; Ravani, A.; Vincenzi, F.; Borea, P.A. et al.
Source: Self-asserted source
Emanuela Ruggiero via Scopus - Elsevier

One-Pot Reaction to Obtain N,N′-Disubstituted Guanidines of Pyrazolo[4,3- e ][1,2,4]triazolo[1,5- c ]pyrimidine Scaffold as Human A<inf>3</inf> Adenosine Receptor Antagonists

Journal of Medicinal Chemistry
2015 | Journal article
EID:

2-s2.0-84937425325

Contributors: Baraldi, P.G.; Baraldi, S.; Saponaro, G.; Aghazadeh Tabrizi, M.; Romagnoli, R.; Ruggiero, E.; Vincenzi, F.; Borea, P.A.; Varani, K.
Source: Self-asserted source
Emanuela Ruggiero via Scopus - Elsevier

Pyrazole phenylcyclohexylcarbamates as inhibitors of human fatty acid amide hydrolases (FAAH)

European Journal of Medicinal Chemistry
2015 | Journal article
EID:

2-s2.0-84929611978

Contributors: Aghazadeh Tabrizi, M.; Baraldi, P.G.; Ruggiero, E.; Saponaro, G.; Baraldi, S.; Romagnoli, R.; Martinelli, A.; Tuccinardi, T.
Source: Self-asserted source
Emanuela Ruggiero via Scopus - Elsevier

New synthesis of diazepino[3,2,1-ij]quinoline and pyrido[1,2,3-de] quinoxalines via addition-elimination followed by cycloacylation

Journal of Heterocyclic Chemistry
2014 | Journal article
EID:

2-s2.0-84894901508

Contributors: Baraldi, P.G.; Ruggiero, E.; Tabrizi, M.A.
Source: Self-asserted source
Emanuela Ruggiero via Scopus - Elsevier

Discovery of 7-oxopyrazolo[1,5-a]pyrimidine-6-carboxamides as potent and selective CB2 cannabinoid receptor inverse agonists

Journal of Medicinal Chemistry
2013 | Journal article
EID:

2-s2.0-84879065619

Contributors: Aghazadeh Tabrizi, M.; Baraldi, P.G.; Saponaro, G.; Moorman, A.R.; Romagnoli, R.; Preti, D.; Baraldi, S.; Ruggiero, E.; Tintori, C.; Tuccinardi, T. et al.
Source: Self-asserted source
Emanuela Ruggiero via Scopus - Elsevier

7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB 2 cannabinoid receptor ligands: Structural investigations around a novel class of full agonists

Journal of Medicinal Chemistry
2012 | Journal article
EID:

2-s2.0-84864245035

Contributors: Baraldi, P.G.; Saponaro, G.; Moorman, A.R.; Romagnoli, R.; Preti, D.; Baraldi, S.; Ruggiero, E.; Varani, K.; Targa, M.; Vincenzi, F. et al.
Source: Self-asserted source
Emanuela Ruggiero via Scopus - Elsevier

Peer review (3 reviews for 3 publications/grants)

Review activity for Drug discovery today. (1)
Review activity for Nature communications (1)
Review activity for Pathogens. (1)